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The map label for this gene is galM [H]

Identifier: 77465570

GI number: 77465570

Start: 667148

End: 668131

Strand: Direct

Name: galM [H]

Synonym: RSP_3572

Alternate gene names: 77465570

Gene position: 667148-668131 (Clockwise)

Preceding gene: 77465569

Following gene: 77465571

Centisome position: 70.75

GC content: 72.97

Gene sequence:

>984_bases
ATGACCCTCACCCGCTTCGGAACCGCCCCTGACGGGCGGCCCGTCCAGCGCATCGCCCTGGCCGCAGGCGACCTCCGCCT
GGCCCTGCTCGACCGAGGCGCCATCCTGCAGGACCTGCGTCTGGCCGGGATCGACTGGCCGCTCACGGCAGGCGCGTCCG
ACCTCGCGGCCTATCTCGGACCGCTCCGCTGGTTCGGCGCCATCGTCGGTCCGGTCGCGAACCGCATCGGCGGCGCCCGG
GCCTGCATCAATGGCCGGCCGACCCGCTTCGTGCCGAACGAGGGCCGGACGCTCCTCCATTCCGGGGCGGCGGGAACCCA
TGCCCGGCACTGGCAGCCGGTCGAGGTCGAGGCGGGCCGCGCGCTCCTGCGGCTCGAACTCGCGGACGGCATCGACGGAT
TTCCCGGCAACCGGCGGCTCGAGGCCGAGTTCGTGCTGGACCCGCCCGCGACGCTCCGGCTGATCCTGACCGCGGTCACG
GATGCGCCGACGCTGATGAACCTCGCCAACCACAGCTACTGGACCCTCGATCCCGAGCCCGGGATCGGCGGCCAGCAGCT
GCAGATCGCGGCGGAGCACTGGCTTCCGGTCGAGGCCGGCCTGCCTACGGGCGAGATCCGCCCCGTATCCGGAGCGATGG
ACTTCCGCGCGGGCCGCCCCCTCGGAGAGACCGAGGGGATCGACCACAATTTCTGCCTCGCCAGTGCGCAGCGAGACCTG
ACCGAGGTGGCGCGCCTCACCGGCCGGTCGGGCGTCCGTCTCACTCTCGCCACCACCGCCCCGGGCCTGCAGGTCTATAC
CGGCCGCGAGATCGACAGCATGCCCTTCGCGGGCCACGGGGGCCGACCGCTCCGGGCCTTCGACGCCATTGCGCTCGAGC
CGCAGCTCTGGCCGGACGCGCCGAACCGGCCGGAGTTCCCCCCGATCACCCTCGCCCCGGGCGAAACCTTCCGCCAGGAG
ACGCGCTTCTCCTTCTCCGCCTGA

Upstream 100 bases:

>100_bases
GAACCTGATCCGCGGCCTCGCCGACGGCATCCTGTCCTGCGTCGCCCCTTGATCTCGCGCGGCCTCCGGCGCAGCCTGCC
CGCCTGCACCGGAGGCGCCC

Downstream 100 bases:

>100_bases
ACCGAGCCGGGTGCCGCGGCTCCGCGACGGGGGTCGTGCCGAGCGCGTCCACAGCTTGCCCGCTTCGGCAGGGGCAAGAC
GCTCCCGGCATCCCGATCCA

Product: putative aldose 1-epimerase protein

Products: NA

Alternate protein names: Galactose mutarotase; Type-1 mutarotase [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MTLTRFGTAPDGRPVQRIALAAGDLRLALLDRGAILQDLRLAGIDWPLTAGASDLAAYLGPLRWFGAIVGPVANRIGGAR
ACINGRPTRFVPNEGRTLLHSGAAGTHARHWQPVEVEAGRALLRLELADGIDGFPGNRRLEAEFVLDPPATLRLILTAVT
DAPTLMNLANHSYWTLDPEPGIGGQQLQIAAEHWLPVEAGLPTGEIRPVSGAMDFRAGRPLGETEGIDHNFCLASAQRDL
TEVARLTGRSGVRLTLATTAPGLQVYTGREIDSMPFAGHGGRPLRAFDAIALEPQLWPDAPNRPEFPPITLAPGETFRQE
TRFSFSA

Sequences:

>Translated_327_residues
MTLTRFGTAPDGRPVQRIALAAGDLRLALLDRGAILQDLRLAGIDWPLTAGASDLAAYLGPLRWFGAIVGPVANRIGGAR
ACINGRPTRFVPNEGRTLLHSGAAGTHARHWQPVEVEAGRALLRLELADGIDGFPGNRRLEAEFVLDPPATLRLILTAVT
DAPTLMNLANHSYWTLDPEPGIGGQQLQIAAEHWLPVEAGLPTGEIRPVSGAMDFRAGRPLGETEGIDHNFCLASAQRDL
TEVARLTGRSGVRLTLATTAPGLQVYTGREIDSMPFAGHGGRPLRAFDAIALEPQLWPDAPNRPEFPPITLAPGETFRQE
TRFSFSA
>Mature_326_residues
TLTRFGTAPDGRPVQRIALAAGDLRLALLDRGAILQDLRLAGIDWPLTAGASDLAAYLGPLRWFGAIVGPVANRIGGARA
CINGRPTRFVPNEGRTLLHSGAAGTHARHWQPVEVEAGRALLRLELADGIDGFPGNRRLEAEFVLDPPATLRLILTAVTD
APTLMNLANHSYWTLDPEPGIGGQQLQIAAEHWLPVEAGLPTGEIRPVSGAMDFRAGRPLGETEGIDHNFCLASAQRDLT
EVARLTGRSGVRLTLATTAPGLQVYTGREIDSMPFAGHGGRPLRAFDAIALEPQLWPDAPNRPEFPPITLAPGETFRQET
RFSFSA

Specific function: Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose [H]

COG id: COG2017

COG function: function code G; Galactose mutarotase and related enzymes

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldose epimerase family [H]

Homologues:

Organism=Homo sapiens, GI20270355, Length=341, Percent_Identity=33.1378299120235, Blast_Score=160, Evalue=2e-39,
Organism=Escherichia coli, GI1786971, Length=340, Percent_Identity=31.4705882352941, Blast_Score=149, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17557428, Length=317, Percent_Identity=28.391167192429, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI115533334, Length=317, Percent_Identity=28.391167192429, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24659048, Length=337, Percent_Identity=31.4540059347181, Blast_Score=140, Evalue=8e-34,
Organism=Drosophila melanogaster, GI24668278, Length=339, Percent_Identity=25.6637168141593, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24668282, Length=329, Percent_Identity=27.9635258358663, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24583720, Length=326, Percent_Identity=26.6871165644172, Blast_Score=107, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018052
- InterPro:   IPR013458
- InterPro:   IPR008183
- InterPro:   IPR015443
- InterPro:   IPR011013
- InterPro:   IPR014718 [H]

Pfam domain/function: PF01263 Aldose_epim [H]

EC number: =5.1.3.3 [H]

Molecular weight: Translated: 35110; Mature: 34979

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTRFGTAPDGRPVQRIALAAGDLRLALLDRGAILQDLRLAGIDWPLTAGASDLAAYLG
CCEECCCCCCCCCHHHHHEEHHCCEEEEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHH
PLRWFGAIVGPVANRIGGARACINGRPTRFVPNEGRTLLHSGAAGTHARHWQPVEVEAGR
HHHHHHHHHHHHHHHCCCCEEEECCCCCEECCCCCCEEEECCCCCCCCCCCCCEEECCCC
ALLRLELADGIDGFPGNRRLEAEFVLDPPATLRLILTAVTDAPTLMNLANHSYWTLDPEP
EEEEEEECCCCCCCCCCCEEEEEEEECCCHHHEEEEHHHCCCCHHHHHCCCCEEEECCCC
GIGGQQLQIAAEHWLPVEAGLPTGEIRPVSGAMDFRAGRPLGETEGIDHNFCLASAQRDL
CCCCCEEEEEHHHCEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHH
TEVARLTGRSGVRLTLATTAPGLQVYTGREIDSMPFAGHGGRPLRAFDAIALEPQLWPDA
HHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCHHHHEEEECCCCCCCC
PNRPEFPPITLAPGETFRQETRFSFSA
CCCCCCCEEEECCCHHHHHHCCCCCCC
>Mature Secondary Structure 
TLTRFGTAPDGRPVQRIALAAGDLRLALLDRGAILQDLRLAGIDWPLTAGASDLAAYLG
CEECCCCCCCCCHHHHHEEHHCCEEEEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHH
PLRWFGAIVGPVANRIGGARACINGRPTRFVPNEGRTLLHSGAAGTHARHWQPVEVEAGR
HHHHHHHHHHHHHHHCCCCEEEECCCCCEECCCCCCEEEECCCCCCCCCCCCCEEECCCC
ALLRLELADGIDGFPGNRRLEAEFVLDPPATLRLILTAVTDAPTLMNLANHSYWTLDPEP
EEEEEEECCCCCCCCCCCEEEEEEEECCCHHHEEEEHHHCCCCHHHHHCCCCEEEECCCC
GIGGQQLQIAAEHWLPVEAGLPTGEIRPVSGAMDFRAGRPLGETEGIDHNFCLASAQRDL
CCCCCEEEEEHHHCEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHH
TEVARLTGRSGVRLTLATTAPGLQVYTGREIDSMPFAGHGGRPLRAFDAIALEPQLWPDA
HHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCHHHHEEEECCCCCCCC
PNRPEFPPITLAPGETFRQETRFSFSA
CCCCCCCEEEECCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7966338; 8905232; 9278503 [H]