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The map label for this gene is iolB [H]

Identifier: 77465291

GI number: 77465291

Start: 343813

End: 344619

Strand: Direct

Name: iolB [H]

Synonym: RSP_3286

Alternate gene names: 77465291

Gene position: 343813-344619 (Clockwise)

Preceding gene: 77465290

Following gene: 77465303

Centisome position: 36.46

GC content: 68.15

Gene sequence:

>807_bases
ATGACGATATTGCTGCACCGGCCCTTCGGCAGCCACGGCAAGGTGCATGAGATCACCCCGGCCTCGGCGGGCTGGCGCTA
TGTGGGCTTCTCTCTCTACCGGCTCCGGCCGGGCGAGGTCGCGGCCGAGACCACGGGGGATCGCGAGGTCATACTGGTCC
TGGTCGAGGGCCGGGCCTCCGTCTCCGGCGGCGGACAGGACTGGGGCGTGCTGGGCGAGCGCTTGTCCGTCTTCGAGAAG
ACGCCGCCGCATTCGCTGTATCTCCCCGACGGCAGCGCGTGGCAGGCGGTGGCCGAGACAGCCTGCACGATCGCCGTCTG
CTCCGCGCCCGGACGCGGCGGCCATGCGGCCCGGCGGATCGGGCCCGAGGGCATCGTGCTCACCGAGCGCGGCAAGGGCA
CGAACCGCCGCCAGATCCACAATATCGCCATGGAGGCGGAGGACGTCTGCGACTCGCTCCTCGTGACCGAGGTCTTCACC
CCGGCGGGTCACTGGTCCTCCTATCCGAGCCACCGCCACGACGAGGACGATTATCCCCGCATCACCTATCTCGAGGAGAC
CTATTATCACCGCCTGAACCCCGCCAACGGGTTCGGCATCCAGCGGGTCTATACCGACGATCTGCGCCTCGACGAGACGA
TGGCGGTGCAGGACGGAGACGTGGTCTGCGTGCCGCGCGGGCACCATCCCTGCGGCGCACCCTACGGGTTCGAGATGTAT
TACCTGAATGTCATGGCCGGCCCGTTGCGCAAATGGCGCTTCGTGGCCGCCCCGGAGGTGGAATGGATCCTGAAGCGGGA
CGCCTGA

Upstream 100 bases:

>100_bases
CCTCTACCGCGTCACTTCGAGGGCGAGGATCCGTTGCGGCTGCGGCCCGGCGCCTGATCCCGGAGGCGGCGGGCCGTGAC
CCTGAGGAGAGGAGAGACCC

Downstream 100 bases:

>100_bases
AGCGGGTCCCGGCCCGCGCCACCGCAGATGCAGGAAGCGCTCCCTTGCGCCAATGCTCTCCGCCAACGGTATCTTGTTTC
AAGGCGGAAAGGCACGGGCG

Product: hypothetical protein

Products: NA

Alternate protein names: 5DG isomerase [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MTILLHRPFGSHGKVHEITPASAGWRYVGFSLYRLRPGEVAAETTGDREVILVLVEGRASVSGGGQDWGVLGERLSVFEK
TPPHSLYLPDGSAWQAVAETACTIAVCSAPGRGGHAARRIGPEGIVLTERGKGTNRRQIHNIAMEAEDVCDSLLVTEVFT
PAGHWSSYPSHRHDEDDYPRITYLEETYYHRLNPANGFGIQRVYTDDLRLDETMAVQDGDVVCVPRGHHPCGAPYGFEMY
YLNVMAGPLRKWRFVAAPEVEWILKRDA

Sequences:

>Translated_268_residues
MTILLHRPFGSHGKVHEITPASAGWRYVGFSLYRLRPGEVAAETTGDREVILVLVEGRASVSGGGQDWGVLGERLSVFEK
TPPHSLYLPDGSAWQAVAETACTIAVCSAPGRGGHAARRIGPEGIVLTERGKGTNRRQIHNIAMEAEDVCDSLLVTEVFT
PAGHWSSYPSHRHDEDDYPRITYLEETYYHRLNPANGFGIQRVYTDDLRLDETMAVQDGDVVCVPRGHHPCGAPYGFEMY
YLNVMAGPLRKWRFVAAPEVEWILKRDA
>Mature_267_residues
TILLHRPFGSHGKVHEITPASAGWRYVGFSLYRLRPGEVAAETTGDREVILVLVEGRASVSGGGQDWGVLGERLSVFEKT
PPHSLYLPDGSAWQAVAETACTIAVCSAPGRGGHAARRIGPEGIVLTERGKGTNRRQIHNIAMEAEDVCDSLLVTEVFTP
AGHWSSYPSHRHDEDDYPRITYLEETYYHRLNPANGFGIQRVYTDDLRLDETMAVQDGDVVCVPRGHHPCGAPYGFEMYY
LNVMAGPLRKWRFVAAPEVEWILKRDA

Specific function: Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate) [H]

COG id: COG3718

COG function: function code G; Uncharacterized enzyme involved in inositol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isomerase iolB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR021120
- InterPro:   IPR014710 [H]

Pfam domain/function: PF04962 KduI [H]

EC number: NA

Molecular weight: Translated: 29743; Mature: 29612

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILLHRPFGSHGKVHEITPASAGWRYVGFSLYRLRPGEVAAETTGDREVILVLVEGRAS
CEEEEECCCCCCCCEEEECCCCCCCEEECEEEEEECCCCEEECCCCCCEEEEEEEECCCC
VSGGGQDWGVLGERLSVFEKTPPHSLYLPDGSAWQAVAETACTIAVCSAPGRGGHAARRI
CCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHCCEEEEEECCCCCCCCHHHHC
GPEGIVLTERGKGTNRRQIHNIAMEAEDVCDSLLVTEVFTPAGHWSSYPSHRHDEDDYPR
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCE
ITYLEETYYHRLNPANGFGIQRVYTDDLRLDETMAVQDGDVVCVPRGHHPCGAPYGFEMY
EEEEEHHHHHHCCCCCCCCEEEEEECCCCCCCEEEECCCCEEEEECCCCCCCCCCCEEEE
YLNVMAGPLRKWRFVAAPEVEWILKRDA
EEEEHHCCHHHEEEEECCCEEEEEECCC
>Mature Secondary Structure 
TILLHRPFGSHGKVHEITPASAGWRYVGFSLYRLRPGEVAAETTGDREVILVLVEGRAS
EEEEECCCCCCCCEEEECCCCCCCEEECEEEEEECCCCEEECCCCCCEEEEEEEECCCC
VSGGGQDWGVLGERLSVFEKTPPHSLYLPDGSAWQAVAETACTIAVCSAPGRGGHAARRI
CCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHCCEEEEEECCCCCCCCHHHHC
GPEGIVLTERGKGTNRRQIHNIAMEAEDVCDSLLVTEVFTPAGHWSSYPSHRHDEDDYPR
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCE
ITYLEETYYHRLNPANGFGIQRVYTDDLRLDETMAVQDGDVVCVPRGHHPCGAPYGFEMY
EEEEEHHHHHHCCCCCCCCEEEEEECCCCCCCEEEECCCCEEEEECCCCCCCCCCCEEEE
YLNVMAGPLRKWRFVAAPEVEWILKRDA
EEEEHHCCHHHEEEEECCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA