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The map label for this gene is fur [C]

Identifier: 77465192

GI number: 77465192

Start: 231397

End: 231837

Strand: Direct

Name: fur [C]

Synonym: RSP_3179

Alternate gene names: 77465192

Gene position: 231397-231837 (Clockwise)

Preceding gene: 77465186

Following gene: 77465193

Centisome position: 24.54

GC content: 66.21

Gene sequence:

>441_bases
ATGCATTTCATGGCAGATGGAATGATGGCACGATCGGCAATCGAACGCGGCACCGACTGGCTGGCGAAGGGCGGCCTGCG
CCCGACGCGGCAGCGCGTGGCGCTGGCGGCGCTTCTGGTCGGCGACGGTCGCGACCGGCATGTGACGGCGGAAAGTCTTT
TCGCCGCAGCCGGCCAGTCCAACGACAAGGTCAGCCTCGCCACCGTCTACAACACGCTGCGCGCCTTCTGCGAAGCGGGC
CTCATGCAGGAGGTCGTGGTGGATGGCGCACGCAGCTATTTCGATACGCGCGTCGACAACCATCCCCACTTCTACTGGGA
AGATACGGCCGACCTCTTCGACGCCCCGGCCGACCAGCTCGAGATCAGCCGCATTCCCGAACTGCCGCCGGGCGCCGAGC
TGAGCCGGGTCGACGTGGTCATCCGCCTCAAGCGTACCTGA

Upstream 100 bases:

>100_bases
GGAAGGGCTGGCAAGGGCGGCGCCCTGCGTCACCGGGGCAGCGGGCCGTCAGAAAAACATGGGTCTTTCCGTTTGAATTT
TGCGCCCGCAATGGGATAAG

Downstream 100 bases:

>100_bases
TCGGCAATTCCCGCTTTATTGCGCAGCGTCTGCCGCTTCTGCGGGCAGGCGTCGCTTTAGCCGGCCCGGCCGCGGAACCG
GTGGCCCGGCCATGTGTTGG

Product: ferric-uptake regulator

Products: NA

Alternate protein names: Ferric Uptake Regulator Fur Family; Transcriptional Regulator Fur Family; FUR Family Transcriptional Regulator; Ferric-Uptake Regulator; Iron Response Regulator; Fe2+/Zn2+ Uptake Regulation Protein; Ferric Uptake Regulator; Fur Family Transcriptional Regulator; Fur Family Ferric Uptake Regulator; Ferric Uptake Regulator FUR Family; Transcriptional Regulator; Ferric Uptake Transcriptional Regulator; Transcriptional Regulator Fur Family Protein; Iron Response Regulator Irr; Transcription Regulator; Iron Transcriptional Regulator Protein

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MHFMADGMMARSAIERGTDWLAKGGLRPTRQRVALAALLVGDGRDRHVTAESLFAAAGQSNDKVSLATVYNTLRAFCEAG
LMQEVVVDGARSYFDTRVDNHPHFYWEDTADLFDAPADQLEISRIPELPPGAELSRVDVVIRLKRT

Sequences:

>Translated_146_residues
MHFMADGMMARSAIERGTDWLAKGGLRPTRQRVALAALLVGDGRDRHVTAESLFAAAGQSNDKVSLATVYNTLRAFCEAG
LMQEVVVDGARSYFDTRVDNHPHFYWEDTADLFDAPADQLEISRIPELPPGAELSRVDVVIRLKRT
>Mature_146_residues
MHFMADGMMARSAIERGTDWLAKGGLRPTRQRVALAALLVGDGRDRHVTAESLFAAAGQSNDKVSLATVYNTLRAFCEAG
LMQEVVVDGARSYFDTRVDNHPHFYWEDTADLFDAPADQLEISRIPELPPGAELSRVDVVIRLKRT

Specific function: Acts As A Global Negative Controlling Element, Employing Fe(2+) As A Cofactor To Bind The Operator Of The Repressed Genes. Regulates The Expression Of Several Outer-Membrane Proteins Including The Iron Transport Operon. [C]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 16174; Mature: 16174

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFMADGMMARSAIERGTDWLAKGGLRPTRQRVALAALLVGDGRDRHVTAESLFAAAGQS
CCCCHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEHHHHHHHHCCCC
NDKVSLATVYNTLRAFCEAGLMQEVVVDGARSYFDTRVDNHPHFYWEDTADLFDAPADQL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHCCCHHHH
EISRIPELPPGAELSRVDVVIRLKRT
HHHCCCCCCCCCCCCEEEEEEEEECC
>Mature Secondary Structure
MHFMADGMMARSAIERGTDWLAKGGLRPTRQRVALAALLVGDGRDRHVTAESLFAAAGQS
CCCCHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEHHHHHHHHCCCC
NDKVSLATVYNTLRAFCEAGLMQEVVVDGARSYFDTRVDNHPHFYWEDTADLFDAPADQL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHCCCHHHH
EISRIPELPPGAELSRVDVVIRLKRT
HHHCCCCCCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA