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The map label for this gene is mcpH [H]

Identifier: 77465097

GI number: 77465097

Start: 127418

End: 129103

Strand: Reverse

Name: mcpH [H]

Synonym: RSP_3083

Alternate gene names: 77465097

Gene position: 129103-127418 (Counterclockwise)

Preceding gene: 77465098

Following gene: 77465095

Centisome position: 13.69

GC content: 69.99

Gene sequence:

>1686_bases
ATGATGAAGGCCTCCATGAAACTGACCATAAAGATCAAGCTCGCCATGACCTTCCTTCTGGTGTTCCTGCTCATGGGGGC
AGGCACCATCTTCGGGCTCCTGGACCTGCGCTCCGCGAACCAGACGCTGCGGTCCATCGTGGACGTCCAGGCCGCCCGGG
TCGAGGCCGCCAGCCGGCTCGAGATCCAGCAGAGCGAGTTCAACGTGGTGCTGCGCGATTATGTGACCGCCCCGACGGCG
ACCGAGCGCGCCAAGCTCAAGCAGGACATCACCCGGATCCGCGCCGATATGAGTGCCAGCATCGAGCGGCTCCAGACACT
CGCGGATGCCGAGGGAGAGAAGCTGATCGCCGCCTATGCCGATCAGCGCAAGGCCGCCGCCGCCTTGAACAATCGGGTCT
TCGCGCTGGCGGACGCGGGCGATGTCGCCGGCGCCTCCCGCCTGCTGGCGGGCGAGTCCCGCGCGGGCATGGTGAAGCTC
GCGGCGAACCTCGAGACCTTCCGCACGCTCTACAAGGACCAGATGACCGAGGCCACGGCCGAAGCGGATCGCGAGCTGAC
GGCGAGCCTTGTCAACCTGTCGGCGCTCGCGCTGGCGGGCATTCTCGCCGGAACCATCGCGGCTACCTTCCTCATCCTCT
CCATCGGGCGCAGGCTCGGCCGGGCGCTGGCGCTGTCGCAGCGCGTCGTGCAGGGGGATCTGACCACCCTGGCCGAGGAG
CGCGGCTCGGACGAGATCGCGCAGCTCCTCAAGGCCAACAACGCCATGATCGTGAAACTGCGCGAGGTTCTGGGGCGGGT
GTGGCTCGCCACCGACCAGGTGGCGGCGAACAGCCAGACCATGGCCGCCACCTCCGAACAGCTGTCGCAGGGCAGCAGCG
AACAGGCGGCCTCCACCGAAGAGGCCTCGGCCTCGGTCGAGGAGATGGCCGCCAACATCCGCCAGACCGCCGACAGTGCG
GGTGAGACCGAACGGATCGCCGCAAAATCGGCCGAAGATGCGCGGGCCTCGGGCGATGCCGTGCGCGAGGCGGTGGCAGC
GATGGCCTCCATCGCCGACCGCATCCTCATCGTGCAGGAGATCGCGCGCCAGACCGACCTTCTCGCCCTCAATGCCGCGG
TCGAGGCCGCGCGGGCGGGCGAGCACGGGCGCGGTTTCGCCGTCGTGGCCAGCGAGGTCCGCAAGCTCGCCGAGCGCAGC
CAGGCGGCGGCGGCCGAGATTTCCGCGCTGTCGGCGCGCACCTCCGGCGTGGCGGCCACGGCGGGCGAGATGCTCCAGCG
GCTCGTGCCGGACATCGAGCGCACGTCCGGCCTCGTCTCCTCGATCTCCGTCGCCTCGCGCGAACTGTCGACGGGGGCGC
AGCAGGTGGCGCTCGCCATCCAGCAGCTCGATCAGGTCACCCAGCAGAACAGCACCGCCGCTGAGGCTCTGGCGAGCGGG
GCGGGTGAACTCTCCGTCGAGGCGGACCAGCTGAAGGAGGCGGTGGGCTTCTTCCGCACCGGAGAGACACAGGCCCCGGT
CGCGCCGCAGACGCGCGCAGTTGCGCCGCACGCACGGCCTTCGGCGCGCGCCGTGCCTCAGCCGTCCCTGCGGCCGGTGC
GGTCGTCCAAGGGCTTCGACTTCGACATCGGCGAGAGCGAGTTCGACGAGCTCGACGCGGCCTTCCAGCGCGCGGGCACC
CGCTGA

Upstream 100 bases:

>100_bases
TTCCGCACAGGCAGGGCAAAAATCCCCGAGGCAGCCTACAATTTTAAGGCTCTGGTGCCGTTACTCTTTCCGACCACCGC
CGGATGAGGCGGAACCCCGG

Downstream 100 bases:

>100_bases
GGCCACCCGGTCCGGGGGGCCGCCCCGGTGGGCGGTCCGCTCCAGGCGATGCGCTTCGGGCCGGGCAAACGCCGCACGCC
CGGCCGGTGCGGCCGGGCGC

Product: methyl accepting chemotaxis protein

Products: NA

Alternate protein names: MCP-I; Serine chemoreceptor protein [H]

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MMKASMKLTIKIKLAMTFLLVFLLMGAGTIFGLLDLRSANQTLRSIVDVQAARVEAASRLEIQQSEFNVVLRDYVTAPTA
TERAKLKQDITRIRADMSASIERLQTLADAEGEKLIAAYADQRKAAAALNNRVFALADAGDVAGASRLLAGESRAGMVKL
AANLETFRTLYKDQMTEATAEADRELTASLVNLSALALAGILAGTIAATFLILSIGRRLGRALALSQRVVQGDLTTLAEE
RGSDEIAQLLKANNAMIVKLREVLGRVWLATDQVAANSQTMAATSEQLSQGSSEQAASTEEASASVEEMAANIRQTADSA
GETERIAAKSAEDARASGDAVREAVAAMASIADRILIVQEIARQTDLLALNAAVEAARAGEHGRGFAVVASEVRKLAERS
QAAAAEISALSARTSGVAATAGEMLQRLVPDIERTSGLVSSISVASRELSTGAQQVALAIQQLDQVTQQNSTAAEALASG
AGELSVEADQLKEAVGFFRTGETQAPVAPQTRAVAPHARPSARAVPQPSLRPVRSSKGFDFDIGESEFDELDAAFQRAGT
R

Sequences:

>Translated_561_residues
MMKASMKLTIKIKLAMTFLLVFLLMGAGTIFGLLDLRSANQTLRSIVDVQAARVEAASRLEIQQSEFNVVLRDYVTAPTA
TERAKLKQDITRIRADMSASIERLQTLADAEGEKLIAAYADQRKAAAALNNRVFALADAGDVAGASRLLAGESRAGMVKL
AANLETFRTLYKDQMTEATAEADRELTASLVNLSALALAGILAGTIAATFLILSIGRRLGRALALSQRVVQGDLTTLAEE
RGSDEIAQLLKANNAMIVKLREVLGRVWLATDQVAANSQTMAATSEQLSQGSSEQAASTEEASASVEEMAANIRQTADSA
GETERIAAKSAEDARASGDAVREAVAAMASIADRILIVQEIARQTDLLALNAAVEAARAGEHGRGFAVVASEVRKLAERS
QAAAAEISALSARTSGVAATAGEMLQRLVPDIERTSGLVSSISVASRELSTGAQQVALAIQQLDQVTQQNSTAAEALASG
AGELSVEADQLKEAVGFFRTGETQAPVAPQTRAVAPHARPSARAVPQPSLRPVRSSKGFDFDIGESEFDELDAAFQRAGT
R
>Mature_561_residues
MMKASMKLTIKIKLAMTFLLVFLLMGAGTIFGLLDLRSANQTLRSIVDVQAARVEAASRLEIQQSEFNVVLRDYVTAPTA
TERAKLKQDITRIRADMSASIERLQTLADAEGEKLIAAYADQRKAAAALNNRVFALADAGDVAGASRLLAGESRAGMVKL
AANLETFRTLYKDQMTEATAEADRELTASLVNLSALALAGILAGTIAATFLILSIGRRLGRALALSQRVVQGDLTTLAEE
RGSDEIAQLLKANNAMIVKLREVLGRVWLATDQVAANSQTMAATSEQLSQGSSEQAASTEEASASVEEMAANIRQTADSA
GETERIAAKSAEDARASGDAVREAVAAMASIADRILIVQEIARQTDLLALNAAVEAARAGEHGRGFAVVASEVRKLAERS
QAAAAEISALSARTSGVAATAGEMLQRLVPDIERTSGLVSSISVASRELSTGAQQVALAIQQLDQVTQQNSTAAEALASG
AGELSVEADQLKEAVGFFRTGETQAPVAPQTRAVAPHARPSARAVPQPSLRPVRSSKGFDFDIGESEFDELDAAFQRAGT
R

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=347, Percent_Identity=35.7348703170029, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1788195, Length=328, Percent_Identity=36.5853658536585, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI1787690, Length=318, Percent_Identity=35.8490566037736, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1788194, Length=290, Percent_Identity=35.8620689655172, Blast_Score=131, Evalue=9e-32,
Organism=Escherichia coli, GI1789453, Length=282, Percent_Identity=30.8510638297872, Blast_Score=112, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 59133; Mature: 59133

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKASMKLTIKIKLAMTFLLVFLLMGAGTIFGLLDLRSANQTLRSIVDVQAARVEAASRL
CCCCCEEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIQQSEFNVVLRDYVTAPTATERAKLKQDITRIRADMSASIERLQTLADAEGEKLIAAYA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
DQRKAAAALNNRVFALADAGDVAGASRLLAGESRAGMVKLAANLETFRTLYKDQMTEATA
HHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EADRELTASLVNLSALALAGILAGTIAATFLILSIGRRLGRALALSQRVVQGDLTTLAEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGSDEIAQLLKANNAMIVKLREVLGRVWLATDQVAANSQTMAATSEQLSQGSSEQAASTE
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHCCHH
EASASVEEMAANIRQTADSAGETERIAAKSAEDARASGDAVREAVAAMASIADRILIVQE
HHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
IARQTDLLALNAAVEAARAGEHGRGFAVVASEVRKLAERSQAAAAEISALSARTSGVAAT
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AGEMLQRLVPDIERTSGLVSSISVASRELSTGAQQVALAIQQLDQVTQQNSTAAEALASG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
AGELSVEADQLKEAVGFFRTGETQAPVAPQTRAVAPHARPSARAVPQPSLRPVRSSKGFD
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
FDIGESEFDELDAAFQRAGTR
CCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MMKASMKLTIKIKLAMTFLLVFLLMGAGTIFGLLDLRSANQTLRSIVDVQAARVEAASRL
CCCCCEEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIQQSEFNVVLRDYVTAPTATERAKLKQDITRIRADMSASIERLQTLADAEGEKLIAAYA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
DQRKAAAALNNRVFALADAGDVAGASRLLAGESRAGMVKLAANLETFRTLYKDQMTEATA
HHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EADRELTASLVNLSALALAGILAGTIAATFLILSIGRRLGRALALSQRVVQGDLTTLAEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGSDEIAQLLKANNAMIVKLREVLGRVWLATDQVAANSQTMAATSEQLSQGSSEQAASTE
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHCCHH
EASASVEEMAANIRQTADSAGETERIAAKSAEDARASGDAVREAVAAMASIADRILIVQE
HHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
IARQTDLLALNAAVEAARAGEHGRGFAVVASEVRKLAERSQAAAAEISALSARTSGVAAT
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AGEMLQRLVPDIERTSGLVSSISVASRELSTGAQQVALAIQQLDQVTQQNSTAAEALASG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
AGELSVEADQLKEAVGFFRTGETQAPVAPQTRAVAPHARPSARAVPQPSLRPVRSSKGFD
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
FDIGESEFDELDAAFQRAGTR
CCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6402709; 7610040; 9278503; 8384293; 6213619; 2033064; 10466731 [H]