BacMap

Definition	Rhodobacter sphaeroides 2.4.1 chromosome 2, complete sequence.
Accession	NC_007494
Length	943,016

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The map label for this gene is fabG [H]

Identifier: 77465077

GI number: 77465077

Start: 102341

End: 103036

Strand: Direct

Name: fabG [H]

Synonym: RSP_3062

Alternate gene names: 77465077

Gene position: 102341-103036 (Clockwise)

Preceding gene: 77465076

Following gene: 77465078

Centisome position: 10.85

GC content: 69.11

Gene sequence:

>696_bases
ATGAGCCGCGTCATCGCCATCACCGGCACGCGCAAGGGCATCGGCCGCGCGCTGGCCGAGACCTATCTCGCGCGCGGCTG
GACCGTCGTCGGCTGCTCGCGCGATGCGAGCGACCTCACGCACCCGGCCTATCGCCACTACACGCTCGACGTGGCCGACG
AGCGGGCGGTCGCGGGCATGATGCAGGATGTGCGCCGGACGCATGGACGGCTCGACGCGCTTCTGAACAATGCCGGCATC
GCCTCGATGAACCATGCGCTGCTGACCCCCGGCAGCACGGTCGAGCGGGTGTTCGCGACCAATGTCTTCGGCACCTTCCT
GTTCTGCCGCGAGGCCGCCAAGCTGATGGGCCGCCGCCGCACCGGCCGGATCGTGAACTTCGCCACCGTGGCCACGCCGC
TCAAGCTCGAGGGCGAGGCGGTCTATGCCGCCTCCAAGGCCGCGGTCGTGTCGCTGACCGAGGTGCTGGCGCGCGAGCTG
GCGCCCATGGGCATCACCGTCAATGCCGTGGGGCCGACCCCGGTGCCCACCGACCTCGTCGGCGCCGTGCCCGAGGAGAA
GATGCGCGCGCTGATCGCCCGGCAGGCCATTCCGCGCTACGGCAAGATGGAGGATGTGCTCAACGTCTGCGACTTCTTCC
TGCGCGACGAATCCGATTTCGTGACCGGCCAGACGATCTATCTCGGAGGGGTCTGA

Upstream 100 bases:

>100_bases
TGGCCTCGGAAGCGGCCATGTCGCGCAAGCGCAGCCCCTACCGCAGCCTGCGCAGCCTCGCCGACTATGCGGCCGAATGC
GCCGCCGGAGCGCAGCAGGC

Downstream 100 bases:

>100_bases
GATGGCCGATGCGCTCGCCACGCTCTTCGCCCGGATGGCCGCAGCGGAGGGGAAGACCGCGCTGATCGAGGCCGACGGCA
CGGCGGTCTCCTATGCCGCG

Product: 3-oxoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MSRVIAITGTRKGIGRALAETYLARGWTVVGCSRDASDLTHPAYRHYTLDVADERAVAGMMQDVRRTHGRLDALLNNAGI
ASMNHALLTPGSTVERVFATNVFGTFLFCREAAKLMGRRRTGRIVNFATVATPLKLEGEAVYAASKAAVVSLTEVLAREL
APMGITVNAVGPTPVPTDLVGAVPEEKMRALIARQAIPRYGKMEDVLNVCDFFLRDESDFVTGQTIYLGGV

Sequences:

>Translated_231_residues
MSRVIAITGTRKGIGRALAETYLARGWTVVGCSRDASDLTHPAYRHYTLDVADERAVAGMMQDVRRTHGRLDALLNNAGI
ASMNHALLTPGSTVERVFATNVFGTFLFCREAAKLMGRRRTGRIVNFATVATPLKLEGEAVYAASKAAVVSLTEVLAREL
APMGITVNAVGPTPVPTDLVGAVPEEKMRALIARQAIPRYGKMEDVLNVCDFFLRDESDFVTGQTIYLGGV
>Mature_230_residues
SRVIAITGTRKGIGRALAETYLARGWTVVGCSRDASDLTHPAYRHYTLDVADERAVAGMMQDVRRTHGRLDALLNNAGIA
SMNHALLTPGSTVERVFATNVFGTFLFCREAAKLMGRRRTGRIVNFATVATPLKLEGEAVYAASKAAVVSLTEVLARELA
PMGITVNAVGPTPVPTDLVGAVPEEKMRALIARQAIPRYGKMEDVLNVCDFFLRDESDFVTGQTIYLGGV

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=239, Percent_Identity=30.5439330543933, Blast_Score=104, Evalue=9e-23,
Organism=Homo sapiens, GI7705925, Length=236, Percent_Identity=30.9322033898305, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI15277342, Length=242, Percent_Identity=28.9256198347107, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI4758504, Length=247, Percent_Identity=30.7692307692308, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI66933014, Length=197, Percent_Identity=27.9187817258883, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI20149619, Length=192, Percent_Identity=28.125, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI32483357, Length=241, Percent_Identity=26.1410788381743, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI109715829, Length=194, Percent_Identity=29.8969072164948, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI19923817, Length=249, Percent_Identity=25.7028112449799, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI59889578, Length=221, Percent_Identity=25.7918552036199, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI83715985, Length=247, Percent_Identity=29.5546558704453, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI31542939, Length=198, Percent_Identity=28.7878787878788, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=26.530612244898, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI4503817, Length=204, Percent_Identity=26.9607843137255, Blast_Score=65, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=234, Percent_Identity=30.7692307692308, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI2367175, Length=241, Percent_Identity=35.6846473029046, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI2367365, Length=230, Percent_Identity=33.9130434782609, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI87082100, Length=242, Percent_Identity=30.5785123966942, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1786812, Length=238, Percent_Identity=29.8319327731092, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1790717, Length=237, Percent_Identity=25.7383966244726, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87082160, Length=167, Percent_Identity=29.3413173652695, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789208, Length=242, Percent_Identity=27.6859504132231, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788459, Length=243, Percent_Identity=27.1604938271605, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789057, Length=254, Percent_Identity=26.3779527559055, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI1789378, Length=237, Percent_Identity=27.4261603375527, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787905, Length=240, Percent_Identity=26.6666666666667, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=237, Percent_Identity=32.0675105485232, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17555706, Length=241, Percent_Identity=27.8008298755187, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI25147288, Length=238, Percent_Identity=26.0504201680672, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17538182, Length=252, Percent_Identity=28.968253968254, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=253, Percent_Identity=26.8774703557312, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=253, Percent_Identity=28.0632411067194, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=240, Percent_Identity=25.8333333333333, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=244, Percent_Identity=25.8196721311475, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=254, Percent_Identity=29.1338582677165, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=27.0992366412214, Blast_Score=70, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=30, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=246, Percent_Identity=24.390243902439, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=245, Percent_Identity=26.1224489795918, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=192, Percent_Identity=27.6041666666667, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=256, Percent_Identity=28.125, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17536651, Length=257, Percent_Identity=27.2373540856031, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=217, Percent_Identity=29.4930875576037, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322067, Length=178, Percent_Identity=27.5280898876405, Blast_Score=69, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24639444, Length=238, Percent_Identity=28.1512605042017, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24643142, Length=237, Percent_Identity=30.379746835443, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21355319, Length=240, Percent_Identity=27.0833333333333, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17737361, Length=245, Percent_Identity=31.0204081632653, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21357041, Length=244, Percent_Identity=28.2786885245902, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI28571526, Length=245, Percent_Identity=30.2040816326531, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI23397609, Length=233, Percent_Identity=27.8969957081545, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24644339, Length=244, Percent_Identity=27.0491803278689, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281364892, Length=168, Percent_Identity=29.7619047619048, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28571387, Length=206, Percent_Identity=28.1553398058252, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641388, Length=200, Percent_Identity=29, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21358495, Length=190, Percent_Identity=26.3157894736842, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24648693, Length=207, Percent_Identity=30.4347826086957, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21355889, Length=207, Percent_Identity=30.4347826086957, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 24956; Mature: 24825

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVIAITGTRKGIGRALAETYLARGWTVVGCSRDASDLTHPAYRHYTLDVADERAVAGM
CCEEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCHHHCCCCHHHEEEEECCHHHHHHHH
MQDVRRTHGRLDALLNNAGIASMNHALLTPGSTVERVFATNVFGTFLFCREAAKLMGRRR
HHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TGRIVNFATVATPLKLEGEAVYAASKAAVVSLTEVLARELAPMGITVNAVGPTPVPTDLV
CCCEEEEEECCCCEEECCCEEEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHH
GAVPEEKMRALIARQAIPRYGKMEDVLNVCDFFLRDESDFVTGQTIYLGGV
HCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEECCCEEEECCC
>Mature Secondary Structure 
SRVIAITGTRKGIGRALAETYLARGWTVVGCSRDASDLTHPAYRHYTLDVADERAVAGM
CEEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCHHHCCCCHHHEEEEECCHHHHHHHH
MQDVRRTHGRLDALLNNAGIASMNHALLTPGSTVERVFATNVFGTFLFCREAAKLMGRRR
HHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TGRIVNFATVATPLKLEGEAVYAASKAAVVSLTEVLARELAPMGITVNAVGPTPVPTDLV
CCCEEEEEECCCCEEECCCEEEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHH
GAVPEEKMRALIARQAIPRYGKMEDVLNVCDFFLRDESDFVTGQTIYLGGV
HCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEECCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1556094; 8905232; 9278503; 1314802 [H]