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The map label for this gene is cocE [H]

Identifier: 77465049

GI number: 77465049

Start: 69625

End: 71628

Strand: Direct

Name: cocE [H]

Synonym: RSP_3036

Alternate gene names: 77465049

Gene position: 69625-71628 (Clockwise)

Preceding gene: 77465048

Following gene: 77465055

Centisome position: 7.38

GC content: 67.81

Gene sequence:

>2004_bases
ATGCAGAACTATTCCGTCAGCGTCACCAGTGACAGGCCGGCGCCCTTCCAGCAGATCACCATCCCGCTGGCCGATGGCAC
GGTGCTGCACGCCCGGCTGTGGCTGCCGCAGACGCCGCTGGCCGACAGGGTGCCGCTGGTCCTCGAATGGATCCCCTATC
GCCAGAGCGACGGCACCGCGCTGGCCGACAGCATGATGCATGGCTACTTCGCCGAACAGGGCATCGCCGCCGCCCGCGTC
GACATCCGCGGATCGGGCAATTCCGACGGACTTCTGCACGACGAATATCTGAAACAGGAACAGGATGACGCCTGCGAGGT
CATCGCCTGGTTCGCTCGGCAGGACTGGTGCAACGGCAATGTCGGGCTGATCGGCATTTCCTGGGGCGGTTTCGCCGGGC
TGCAGATCGCGGCGCGCCGGCCGCCGGCGCTGAAATGCATCATTACCGCCTGTTCCACCGACAACCGCTATACCGATGAC
GTCCACTACATGGGCGGCGCCCTTCTGTCGGACGGCATGCAATGGGGCAGCGGCCTGTTCGCGCAGCTGGGCCGGCCCGC
CGATCCCAAGCATGTGGGCGACCGCTGGCGCGAGATGTGGATGAACCGGCTGGAAGGCATCAAGGAGCCGCCGCTGGCCA
CCTGGATGCAGCACACGACCTACGACGACTTCTGGAAGCACGGGTCGGTCTGCGAGGATTACGACGAGATCCAATGCGCG
GTCTGGGCAGTCGGCGGCTGGGTCGACGGCTATACCGACCCGATCCTGCGGCTGATGGAGAAGCTCAGCGTCCCGAAGAA
GGCGCTGATCGGGCCCTGGACGCATATGTATCCGACCTGGGGCCAGCCCGGCCCGCAGATCGGCTTCCTGCAGGAGGCGA
TGCGCTGGTGGCGCCACTGGCTGATGGACGAGGACACCGGCATCATGGACGAGCCGCAGCTGACCCTGTGGCTGGGCAAG
GATCCGAAGCCCGACACCCGCGCGCCGGATATCGGCGGCCGCTGGATCGGCCTGCCGGCCTGGCCGCCTGCCGCGCCGGC
ACAGACGCTCTTTGCCGACGATCGCCGCCTGGCCTCCGCGCCGGGGCCGGTCGAGCCAGAGATCGTCGTCGACAGTCCGC
TGTCGCTCGGCACCCAGGGGGGCGAATGGTGCCCGCTGGATGGCGGCGGCAACGGCCCGGAATTCGCCGGCGATGCGCGG
ATGGATGACGGCATGTCGCTCTGCTTCGACACCACTCCGCTGGCCGAGGCCTTCCATCTGGTCGGCATGCCGGTGCTGCG
CCTGCGGCTCGCGTTCGAGGGCGACCATGCGCTGATCGTCCTGCGTCTGAACGAGGTCTGGCCGGACGGACTGTCGGGCC
GCGTCACCTATGGCATTCGCCGCCTTGCCCGCCCCGAAGGCGTCGCGCCGGGCGAGATGCACGAGGTGGAACTGCCGCTG
AAGGGCGTCGCGCATGAATTCAGCCCGGGCCGCCGCATCCGGCTGGCGATCTCGACCAGCTACTGGCCGCTGGTCTGGCC
GGAACCGCGGCTGAACGCGATCACCCTCGATCCCGCCTCGCTGCGGTTCGATCTGCCGGGCATGCCGCCCGAGGCCAGCC
ATGACCAGCCGGCCTTCGGCCCGGCGATCCACGCCTGCCCAGTGCCCTCGCAGGTGCTGGTCCCGGGCGAGATCAGCCGC
AAGGTCCATCAGGATCTGGCCGGCGGCAAGGTCGAGCTGGTCTCGACCTCGCACCGCGCGACATGGGAACTGGGCGGTCT
GGTCATGGGCGGCTATGGCGGCCACAGCTATTCCGTCATGCCCGATGACGGCGCATCGGCCCGGGCACGCTTCTTCTCGG
TTCAGACCTACGAGCGCGAGGCCCTGGGCTGGAAGATCCGCCTTGAATCGAGCTCGGAAGTCAGCTGGCAGGACGGCCGC
ATGGTCCTTGCCTCGCACTACGAGGCCTTCGAGGGCGATGAGAAGGTCTTTGCCCGCAACTGGCTGCATCGGATCGATTA
TTGA

Upstream 100 bases:

>100_bases
GGTATCCCGGCCCCGACCTCATGGCCGCCGATCCTGACCCCTCTTCCGCGTCGCGGGCCTGAGTTCCCTCCACGCCCGCG
CCTCCTGAAAGGACCCCGAT

Downstream 100 bases:

>100_bases
CCCGATGGCCGCCGCCGGAACAGGGGCGGCGGCCATGGTTCGTGCCCCGGGATGGCGCGCTCCGACCGATCACGCCCGGC
GATCTGCGTCGTGACCCCGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 667; Mature: 667

Protein sequence:

>667_residues
MQNYSVSVTSDRPAPFQQITIPLADGTVLHARLWLPQTPLADRVPLVLEWIPYRQSDGTALADSMMHGYFAEQGIAAARV
DIRGSGNSDGLLHDEYLKQEQDDACEVIAWFARQDWCNGNVGLIGISWGGFAGLQIAARRPPALKCIITACSTDNRYTDD
VHYMGGALLSDGMQWGSGLFAQLGRPADPKHVGDRWREMWMNRLEGIKEPPLATWMQHTTYDDFWKHGSVCEDYDEIQCA
VWAVGGWVDGYTDPILRLMEKLSVPKKALIGPWTHMYPTWGQPGPQIGFLQEAMRWWRHWLMDEDTGIMDEPQLTLWLGK
DPKPDTRAPDIGGRWIGLPAWPPAAPAQTLFADDRRLASAPGPVEPEIVVDSPLSLGTQGGEWCPLDGGGNGPEFAGDAR
MDDGMSLCFDTTPLAEAFHLVGMPVLRLRLAFEGDHALIVLRLNEVWPDGLSGRVTYGIRRLARPEGVAPGEMHEVELPL
KGVAHEFSPGRRIRLAISTSYWPLVWPEPRLNAITLDPASLRFDLPGMPPEASHDQPAFGPAIHACPVPSQVLVPGEISR
KVHQDLAGGKVELVSTSHRATWELGGLVMGGYGGHSYSVMPDDGASARARFFSVQTYEREALGWKIRLESSSEVSWQDGR
MVLASHYEAFEGDEKVFARNWLHRIDY

Sequences:

>Translated_667_residues
MQNYSVSVTSDRPAPFQQITIPLADGTVLHARLWLPQTPLADRVPLVLEWIPYRQSDGTALADSMMHGYFAEQGIAAARV
DIRGSGNSDGLLHDEYLKQEQDDACEVIAWFARQDWCNGNVGLIGISWGGFAGLQIAARRPPALKCIITACSTDNRYTDD
VHYMGGALLSDGMQWGSGLFAQLGRPADPKHVGDRWREMWMNRLEGIKEPPLATWMQHTTYDDFWKHGSVCEDYDEIQCA
VWAVGGWVDGYTDPILRLMEKLSVPKKALIGPWTHMYPTWGQPGPQIGFLQEAMRWWRHWLMDEDTGIMDEPQLTLWLGK
DPKPDTRAPDIGGRWIGLPAWPPAAPAQTLFADDRRLASAPGPVEPEIVVDSPLSLGTQGGEWCPLDGGGNGPEFAGDAR
MDDGMSLCFDTTPLAEAFHLVGMPVLRLRLAFEGDHALIVLRLNEVWPDGLSGRVTYGIRRLARPEGVAPGEMHEVELPL
KGVAHEFSPGRRIRLAISTSYWPLVWPEPRLNAITLDPASLRFDLPGMPPEASHDQPAFGPAIHACPVPSQVLVPGEISR
KVHQDLAGGKVELVSTSHRATWELGGLVMGGYGGHSYSVMPDDGASARARFFSVQTYEREALGWKIRLESSSEVSWQDGR
MVLASHYEAFEGDEKVFARNWLHRIDY
>Mature_667_residues
MQNYSVSVTSDRPAPFQQITIPLADGTVLHARLWLPQTPLADRVPLVLEWIPYRQSDGTALADSMMHGYFAEQGIAAARV
DIRGSGNSDGLLHDEYLKQEQDDACEVIAWFARQDWCNGNVGLIGISWGGFAGLQIAARRPPALKCIITACSTDNRYTDD
VHYMGGALLSDGMQWGSGLFAQLGRPADPKHVGDRWREMWMNRLEGIKEPPLATWMQHTTYDDFWKHGSVCEDYDEIQCA
VWAVGGWVDGYTDPILRLMEKLSVPKKALIGPWTHMYPTWGQPGPQIGFLQEAMRWWRHWLMDEDTGIMDEPQLTLWLGK
DPKPDTRAPDIGGRWIGLPAWPPAAPAQTLFADDRRLASAPGPVEPEIVVDSPLSLGTQGGEWCPLDGGGNGPEFAGDAR
MDDGMSLCFDTTPLAEAFHLVGMPVLRLRLAFEGDHALIVLRLNEVWPDGLSGRVTYGIRRLARPEGVAPGEMHEVELPL
KGVAHEFSPGRRIRLAISTSYWPLVWPEPRLNAITLDPASLRFDLPGMPPEASHDQPAFGPAIHACPVPSQVLVPGEISR
KVHQDLAGGKVELVSTSHRATWELGGLVMGGYGGHSYSVMPDDGASARARFFSVQTYEREALGWKIRLESSSEVSWQDGR
MVLASHYEAFEGDEKVFARNWLHRIDY

Specific function: Hydrolyzes cocaine to benzoate and ecgonine methyl ester, endowing the bacteria with the ability to utilize cocaine as a sole source of carbon and energy for growth, as this bacterium lives in the rhizosphere of coca plants [H]

COG id: COG2936

COG function: function code R; Predicted acyl esterases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha/beta hydrolase family. Carboxylesterase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005674
- InterPro:   IPR008979
- InterPro:   IPR013736
- InterPro:   IPR000383 [H]

Pfam domain/function: PF02129 Peptidase_S15; PF08530 PepX_C [H]

EC number: NA

Molecular weight: Translated: 74005; Mature: 74005

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNYSVSVTSDRPAPFQQITIPLADGTVLHARLWLPQTPLADRVPLVLEWIPYRQSDGTA
CCCCEEEEECCCCCCCEEEEEEECCCEEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCH
LADSMMHGYFAEQGIAAARVDIRGSGNSDGLLHDEYLKQEQDDACEVIAWFARQDWCNGN
HHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHCCCCCC
VGLIGISWGGFAGLQIAARRPPALKCIITACSTDNRYTDDVHYMGGALLSDGMQWGSGLF
EEEEEEECCCCCCEEEECCCCCCEEEEEEEECCCCCCCCHHHHHCCHHHHCCHHHCCHHH
AQLGRPADPKHVGDRWREMWMNRLEGIKEPPLATWMQHTTYDDFWKHGSVCEDYDEIQCA
HHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHCCCCCCCCHHHCEEE
VWAVGGWVDGYTDPILRLMEKLSVPKKALIGPWTHMYPTWGQPGPQIGFLQEAMRWWRHW
EEEECCCCCCCHHHHHHHHHHHCCCHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHH
LMDEDTGIMDEPQLTLWLGKDPKPDTRAPDIGGRWIGLPAWPPAAPAQTLFADDRRLASA
HCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHCCCCHHCCC
PGPVEPEIVVDSPLSLGTQGGEWCPLDGGGNGPEFAGDARMDDGMSLCFDTTPLAEAFHL
CCCCCCCEEECCCHHCCCCCCCEECCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHH
VGMPVLRLRLAFEGDHALIVLRLNEVWPDGLSGRVTYGIRRLARPEGVAPGEMHEVELPL
HCCCEEEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEECCH
KGVAHEFSPGRRIRLAISTSYWPLVWPEPRLNAITLDPASLRFDLPGMPPEASHDQPAFG
HHHHHCCCCCCEEEEEEECCCCEEECCCCCCCEEEECHHHEEEECCCCCCCCCCCCCCCC
PAIHACPVPSQVLVPGEISRKVHQDLAGGKVELVSTSHRATWELGGLVMGGYGGHSYSVM
CCEECCCCCCCEECCHHHHHHHHHHHCCCEEEEEECCCCCEEEECCEEEECCCCCEEEEC
PDDGASARARFFSVQTYEREALGWKIRLESSSEVSWQDGRMVLASHYEAFEGDEKVFARN
CCCCCCCCEEEEEEEEEHHHHCEEEEEECCCCCCCCCCCCEEEEEHHHHHCCCHHHHHHH
WLHRIDY
HHHHCCC
>Mature Secondary Structure
MQNYSVSVTSDRPAPFQQITIPLADGTVLHARLWLPQTPLADRVPLVLEWIPYRQSDGTA
CCCCEEEEECCCCCCCEEEEEEECCCEEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCH
LADSMMHGYFAEQGIAAARVDIRGSGNSDGLLHDEYLKQEQDDACEVIAWFARQDWCNGN
HHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHCCCCCC
VGLIGISWGGFAGLQIAARRPPALKCIITACSTDNRYTDDVHYMGGALLSDGMQWGSGLF
EEEEEEECCCCCCEEEECCCCCCEEEEEEEECCCCCCCCHHHHHCCHHHHCCHHHCCHHH
AQLGRPADPKHVGDRWREMWMNRLEGIKEPPLATWMQHTTYDDFWKHGSVCEDYDEIQCA
HHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHCCCCCCCCHHHCEEE
VWAVGGWVDGYTDPILRLMEKLSVPKKALIGPWTHMYPTWGQPGPQIGFLQEAMRWWRHW
EEEECCCCCCCHHHHHHHHHHHCCCHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHH
LMDEDTGIMDEPQLTLWLGKDPKPDTRAPDIGGRWIGLPAWPPAAPAQTLFADDRRLASA
HCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHCCCCHHCCC
PGPVEPEIVVDSPLSLGTQGGEWCPLDGGGNGPEFAGDARMDDGMSLCFDTTPLAEAFHL
CCCCCCCEEECCCHHCCCCCCCEECCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHH
VGMPVLRLRLAFEGDHALIVLRLNEVWPDGLSGRVTYGIRRLARPEGVAPGEMHEVELPL
HCCCEEEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEECCH
KGVAHEFSPGRRIRLAISTSYWPLVWPEPRLNAITLDPASLRFDLPGMPPEASHDQPAFG
HHHHHCCCCCCEEEEEEECCCCEEECCCCCCCEEEECHHHEEEECCCCCCCCCCCCCCCC
PAIHACPVPSQVLVPGEISRKVHQDLAGGKVELVSTSHRATWELGGLVMGGYGGHSYSVM
CCEECCCCCCCEECCHHHHHHHHHHHCCCEEEEEECCCCCEEEECCEEEECCCCCEEEEC
PDDGASARARFFSVQTYEREALGWKIRLESSSEVSWQDGRMVLASHYEAFEGDEKVFARN
CCCCCCCCEEEEEEEEEHHHHCEEEEEECCCCCCCCCCCCEEEEEHHHHHCCCHHHHHHH
WLHRIDY
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10698749; 11742345; 12369817 [H]