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The map label for this gene is abcA [H]

Identifier: 77461905

GI number: 77461905

Start: 6370302

End: 6371552

Strand: Direct

Name: abcA [H]

Synonym: Pfl01_5685

Alternate gene names: 77461905

Gene position: 6370302-6371552 (Clockwise)

Preceding gene: 77461904

Following gene: 77461906

Centisome position: 98.94

GC content: 63.39

Gene sequence:

>1251_bases
ATGGGGCACATACGCGTCACTGGCCTGGGCAAGGCCTACAAACAGTACCCAACTCGCTGGAGCCGCCTGGCGGAATGGCT
GATTCCGTTTTCGCCGATGCGCCATCGCCAGCACTGGGTGCTGCAGGACGTGAATTTCGAAATCGCCCCCGGTGAAGCGG
TGGGCATTGTCGGGGTCAACGGCGCCGGAAAAAGCACCTTGCTCAAGATGATCACCGGCACCACCCAACCGACCTGCGGC
CAGATTCAGCTCGAGGGCCGGGTCGCGGCGCTGCTGGAACTGGGCATGGGTTTTCATCCGGACTTCACCGGTCGGCAGAA
TGCAGTGATGGCCGGGCAACTGCTGGGCATGCAGGTCGAAGACATCGAAGCACTCATGCCGGACATTGAACGCTTCGCGG
AAATCGGCGAGGCCATCGATCACCCGGTGCGCACCTACTCCAGCGGCATGCAGATGCGCCTGGCCTTCAGCGTCGCCACC
GCGCGACGCCCGGACATTCTGATCGTCGACGAAGCGCTGTCGGTGGGCGATGCCTACTTCCAGCACAAGAGCTTCGACCG
CATCCGCAGCTTCCGCAAGGCTGGCACCACGCTGCTGATCGTGTCCCACGACCGCTCGGCGATCCAGTCGATCTGCGACT
CGGCGATCCTGCTCGAAGGCGGCCACATGGTGATGCACGACAAGCCCGAAGCGGTCATGGATTACTACAACGCCCTGCTT
GCTGAACGCGAAGGCCAGACCGTGCGCCAGGAACTGCTCGACGGCGGACAAGTGCGCACCGTGTCCGGCACCGGCGAGGC
CGGGATCCTCAGCGTACGCCTGCTCGATGAACGCGAACGTTCCATCGACGCTGCCGAAGTCGGTCAGCCGGTGACCCTGG
AAGTCGAGGTAGAGATTCGCCAGGACATCGAGCGGCTGGTGCTCGGCTTCATGATCAAGGATCGCCTGGGCCAGGCCATG
TACGGCATCAATACCCACCGCCAGAATCAGGCGCTGGAAGACCTGCGTGCGGGCGAGCGCATCACCTATCGCTTCGCGTT
CGTCATGGGCCTGGGCAAGGGCAATTACTCCGTGGCCCTGAGCCTGTCGCGACTGGACTCGCACCTGGACCGCAACTTCG
AATGGCGTGACTACGGGCTGGTGTTCCACGTGATCAACAACCGTCAGGAAGATTTCGTCGGCTGTTCCTGGCTGGGCGCC
AGCACCTCGATCACCCGCCACGCGGACAGCCTCGCGGAGCGTGCGCCATGA

Upstream 100 bases:

>100_bases
GGAGTTCGCTGCTGCCGATCTTCGTGATCGGCCTGCTGTTGTGCGCAGTCGGCCTGCGCCTGTTTCGCCGGCGGGTCGGC
GAAATGGTGGATGAACTCTG

Downstream 100 bases:

>100_bases
CCCGCCTGCTGGTCGAATGCACCCACGTGTTCAAACACCCGAAGGTCAATTCGGGGATTCAGCGGGTGGTGCGCAACGTC
ATCAAACAGCTGCCGCCGAG

Product: ABC transporter-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MGHIRVTGLGKAYKQYPTRWSRLAEWLIPFSPMRHRQHWVLQDVNFEIAPGEAVGIVGVNGAGKSTLLKMITGTTQPTCG
QIQLEGRVAALLELGMGFHPDFTGRQNAVMAGQLLGMQVEDIEALMPDIERFAEIGEAIDHPVRTYSSGMQMRLAFSVAT
ARRPDILIVDEALSVGDAYFQHKSFDRIRSFRKAGTTLLIVSHDRSAIQSICDSAILLEGGHMVMHDKPEAVMDYYNALL
AEREGQTVRQELLDGGQVRTVSGTGEAGILSVRLLDERERSIDAAEVGQPVTLEVEVEIRQDIERLVLGFMIKDRLGQAM
YGINTHRQNQALEDLRAGERITYRFAFVMGLGKGNYSVALSLSRLDSHLDRNFEWRDYGLVFHVINNRQEDFVGCSWLGA
STSITRHADSLAERAP

Sequences:

>Translated_416_residues
MGHIRVTGLGKAYKQYPTRWSRLAEWLIPFSPMRHRQHWVLQDVNFEIAPGEAVGIVGVNGAGKSTLLKMITGTTQPTCG
QIQLEGRVAALLELGMGFHPDFTGRQNAVMAGQLLGMQVEDIEALMPDIERFAEIGEAIDHPVRTYSSGMQMRLAFSVAT
ARRPDILIVDEALSVGDAYFQHKSFDRIRSFRKAGTTLLIVSHDRSAIQSICDSAILLEGGHMVMHDKPEAVMDYYNALL
AEREGQTVRQELLDGGQVRTVSGTGEAGILSVRLLDERERSIDAAEVGQPVTLEVEVEIRQDIERLVLGFMIKDRLGQAM
YGINTHRQNQALEDLRAGERITYRFAFVMGLGKGNYSVALSLSRLDSHLDRNFEWRDYGLVFHVINNRQEDFVGCSWLGA
STSITRHADSLAERAP
>Mature_415_residues
GHIRVTGLGKAYKQYPTRWSRLAEWLIPFSPMRHRQHWVLQDVNFEIAPGEAVGIVGVNGAGKSTLLKMITGTTQPTCGQ
IQLEGRVAALLELGMGFHPDFTGRQNAVMAGQLLGMQVEDIEALMPDIERFAEIGEAIDHPVRTYSSGMQMRLAFSVATA
RRPDILIVDEALSVGDAYFQHKSFDRIRSFRKAGTTLLIVSHDRSAIQSICDSAILLEGGHMVMHDKPEAVMDYYNALLA
EREGQTVRQELLDGGQVRTVSGTGEAGILSVRLLDERERSIDAAEVGQPVTLEVEVEIRQDIERLVLGFMIKDRLGQAMY
GINTHRQNQALEDLRAGERITYRFAFVMGLGKGNYSVALSLSRLDSHLDRNFEWRDYGLVFHVINNRQEDFVGCSWLGAS
TSITRHADSLAERAP

Specific function: Influences the expression of the surface array protein gene (vapA). May have both regulatory and transport activities [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI6005701, Length=207, Percent_Identity=28.9855072463768, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI27477115, Length=215, Percent_Identity=27.4418604651163, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI153792144, Length=204, Percent_Identity=26.4705882352941, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI31657092, Length=224, Percent_Identity=25.4464285714286, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI105990541, Length=190, Percent_Identity=28.4210526315789, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI27436953, Length=233, Percent_Identity=23.6051502145923, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI27262624, Length=193, Percent_Identity=23.8341968911917, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI27262626, Length=193, Percent_Identity=23.8341968911917, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI116734710, Length=227, Percent_Identity=25.1101321585903, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI150417984, Length=204, Percent_Identity=25.4901960784314, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI45446740, Length=187, Percent_Identity=25.1336898395722, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI47078218, Length=187, Percent_Identity=25.1336898395722, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI27881501, Length=199, Percent_Identity=23.6180904522613, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI30795238, Length=199, Percent_Identity=23.6180904522613, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI4557481, Length=226, Percent_Identity=27.4336283185841, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI87081709, Length=208, Percent_Identity=25.9615384615385, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1786398, Length=224, Percent_Identity=23.2142857142857, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788165, Length=203, Percent_Identity=29.5566502463054, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI87081791, Length=210, Percent_Identity=24.7619047619048, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788225, Length=211, Percent_Identity=28.436018957346, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790467, Length=207, Percent_Identity=27.0531400966184, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789751, Length=181, Percent_Identity=28.1767955801105, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI48994997, Length=213, Percent_Identity=28.169014084507, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1789873, Length=199, Percent_Identity=28.1407035175879, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1789032, Length=255, Percent_Identity=23.1372549019608, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082267, Length=193, Percent_Identity=25.9067357512953, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789672, Length=214, Percent_Identity=25.7009345794392, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082268, Length=207, Percent_Identity=27.536231884058, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI48994943, Length=240, Percent_Identity=25, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788761, Length=208, Percent_Identity=25, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI87081834, Length=185, Percent_Identity=28.6486486486486, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789891, Length=212, Percent_Identity=24.5283018867925, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789593, Length=208, Percent_Identity=25.4807692307692, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788210, Length=204, Percent_Identity=28.4313725490196, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787370, Length=206, Percent_Identity=21.8446601941748, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87081782, Length=201, Percent_Identity=27.8606965174129, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI48995001, Length=200, Percent_Identity=29, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786703, Length=202, Percent_Identity=28.7128712871287, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787041, Length=200, Percent_Identity=25, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1788897, Length=214, Percent_Identity=24.7663551401869, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1786319, Length=264, Percent_Identity=23.4848484848485, Blast_Score=62, Evalue=8e-11,
Organism=Escherichia coli, GI1790525, Length=208, Percent_Identity=25.4807692307692, Blast_Score=62, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17565586, Length=192, Percent_Identity=26.5625, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17510237, Length=193, Percent_Identity=24.8704663212435, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=197, Percent_Identity=21.3197969543147, Blast_Score=65, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17569081, Length=199, Percent_Identity=27.6381909547739, Blast_Score=65, Evalue=1e-10,
Organism=Drosophila melanogaster, GI116007184, Length=195, Percent_Identity=27.6923076923077, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI221500365, Length=195, Percent_Identity=27.6923076923077, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24643674, Length=295, Percent_Identity=24.0677966101695, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221512771, Length=197, Percent_Identity=23.8578680203046, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI28573571, Length=302, Percent_Identity=20.1986754966887, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573573, Length=302, Percent_Identity=20.1986754966887, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45550390, Length=205, Percent_Identity=26.8292682926829, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650853, Length=226, Percent_Identity=22.1238938053097, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24650855, Length=226, Percent_Identity=22.1238938053097, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281362751, Length=220, Percent_Identity=24.0909090909091, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI85725262, Length=214, Percent_Identity=26.6355140186916, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI281363262, Length=211, Percent_Identity=26.0663507109005, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24653245, Length=211, Percent_Identity=26.0663507109005, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24666092, Length=194, Percent_Identity=24.7422680412371, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: 3.6.3.30 [C]

Molecular weight: Translated: 46354; Mature: 46222

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHIRVTGLGKAYKQYPTRWSRLAEWLIPFSPMRHRQHWVLQDVNFEIAPGEAVGIVGVN
CCCEEEEECCHHHHHCCHHHHHHHHHHCCCCCHHHCCCEEEEECCEEECCCCEEEEEEEC
GAGKSTLLKMITGTTQPTCGQIQLEGRVAALLELGMGFHPDFTGRQNAVMAGQLLGMQVE
CCCHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHCCCCCCCCCCCCCCEEHHHHHCCCHH
DIEALMPDIERFAEIGEAIDHPVRTYSSGMQMRLAFSVATARRPDILIVDEALSVGDAYF
HHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEEEEEHHCCCCCEEEEECHHHHHHHHH
QHKSFDRIRSFRKAGTTLLIVSHDRSAIQSICDSAILLEGGHMVMHDKPEAVMDYYNALL
HHCCHHHHHHHHHCCCEEEEEECCHHHHHHHCCCEEEEECCEEEEECCCHHHHHHHHHHH
AEREGQTVRQELLDGGQVRTVSGTGEAGILSVRLLDERERSIDAAEVGQPVTLEVEVEIR
HHCCCHHHHHHHHCCCCEEEECCCCCCCEEEEEEECCHHHCCCHHHCCCCEEEEEEEHHH
QDIERLVLGFMIKDRLGQAMYGINTHRQNQALEDLRAGERITYRFAFVMGLGKGNYSVAL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEEEEEEEECCCCEEEEE
SLSRLDSHLDRNFEWRDYGLVFHVINNRQEDFVGCSWLGASTSITRHADSLAERAP
EHHHHHHHHCCCCCEECCCEEEEEECCCCCCCCCEEECCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
GHIRVTGLGKAYKQYPTRWSRLAEWLIPFSPMRHRQHWVLQDVNFEIAPGEAVGIVGVN
CCEEEEECCHHHHHCCHHHHHHHHHHCCCCCHHHCCCEEEEECCEEECCCCEEEEEEEC
GAGKSTLLKMITGTTQPTCGQIQLEGRVAALLELGMGFHPDFTGRQNAVMAGQLLGMQVE
CCCHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHCCCCCCCCCCCCCCEEHHHHHCCCHH
DIEALMPDIERFAEIGEAIDHPVRTYSSGMQMRLAFSVATARRPDILIVDEALSVGDAYF
HHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEEEEEHHCCCCCEEEEECHHHHHHHHH
QHKSFDRIRSFRKAGTTLLIVSHDRSAIQSICDSAILLEGGHMVMHDKPEAVMDYYNALL
HHCCHHHHHHHHHCCCEEEEEECCHHHHHHHCCCEEEEECCEEEEECCCHHHHHHHHHHH
AEREGQTVRQELLDGGQVRTVSGTGEAGILSVRLLDERERSIDAAEVGQPVTLEVEVEIR
HHCCCHHHHHHHHCCCCEEEECCCCCCCEEEEEEECCHHHCCCHHHCCCCEEEEEEEHHH
QDIERLVLGFMIKDRLGQAMYGINTHRQNQALEDLRAGERITYRFAFVMGLGKGNYSVAL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEEEEEEEECCCCEEEEE
SLSRLDSHLDRNFEWRDYGLVFHVINNRQEDFVGCSWLGASTSITRHADSLAERAP
EHHHHHHHHCCCCCEECCCEEEEEECCCCCCCCCEEECCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8491726 [H]