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The map label for this gene is rmlA2 [C]

Identifier: 77461735

GI number: 77461735

Start: 6180224

End: 6180937

Strand: Direct

Name: rmlA2 [C]

Synonym: Pfl01_5514

Alternate gene names: 77461735

Gene position: 6180224-6180937 (Clockwise)

Preceding gene: 77461734

Following gene: 77461738

Centisome position: 95.99

GC content: 60.5

Gene sequence:

>714_bases
GTGAAAGCCATTATTCTGGCTGCCGGACGTGGCAGTCGCATGAAAAGCCTCACGGATGAGCGCCCCAAGTGCCTGGTCGA
GCTGCGAGGCAAAGCCCTGCTCGAATGGCAGCTGGAATCCTTGCGCGCGGCGGGCATCAGCGAAATCGCCATAGTGACCG
GCTATAAAAGAGAGTGGCTGGCCGAGCGTGACCTGATCGAATTCCACAACCCACGCTGGGCGGACACCAACATGGTGTCG
TCGCTGGCGTGCGCCGAATCCTGGCTGCAGGGCCAGCCGTGCATCGTGAGTTATTCCGATATTTTCTACAGCCCGGACGC
CGTTCGTTCGTTGGTGACCAACGAAGCATCGCTGGCCGTCACCTACGACCCCCATTGGTTGAAATTGTGGACGCAGCGTT
TCGGCGATCCGTTGCTGGATGCCGAAACGTTCCGCCTGACCGACGCCGGCACGCTGGCCGAAATCGGCAACAAGCCGCAA
TCGGTGGACGAAGTTCAGGGTCAGTATATGGGGCTGCTGCGCTTCACCCCGCAGGGTTGGGCAGAAGTCGTTCGGCTACG
AGCCGAACTGACCCCGGAACAACGCGACAAGATGCACATGACCAACACCCTGCAACGTGTCATCGATGCAGGTCGGGTTC
CGGTCGCGGCCGTGGCCTACAGCGGAGAATGGGGAGAGGTCGACTCCAGCGAAGACCTCTCCGCTTACCAGTAA

Upstream 100 bases:

>100_bases
CCGGAGCGCGAAGCGGATTTTGCCACCCACGACCTAGAACGTATCCGGCAGCTGTTCGGCGAACCTGACTCCATTCAATA
ACCCACGGGATAGACGTGTT

Downstream 100 bases:

>100_bases
GCGGGCACGGCGCCTCAACGGAAGCGGTCGACTTCCTGGCGCAGGTCGGCTGCCAGGCCTTCCAGTTCCTTGGCGGTGAT
TGCCAGGTTCGATACCACTT

Product: nucleotidyl transferase

Products: dTDPglucose; Diphosphate [C]

Alternate protein names: Phosphoenolpyruvate Phosphomutase; Nucleotidyltransferase Family Protein; Transferase; Sugar Nucleotidyltransferase; Glucose-1-Phosphate Cytidylyltransferase; Sugar Metabolism Cluster Protein; Sugar Nucleotidyltransferase-Like Protein; Sugar-Phosphate Nucleotydyltransferase; LicC-Like Protein; Nucleoside-Diphosphate-Sugar Pyrophosphorylase; Nucleotidyl Transferase WchZ; Nucleotidyl Transferase Superfamily; Sugar-1-Phosphate Nucleotidyltransferase; LicC Protein; Phosphoenolpyruvate Mutase; N-Acetylglucosamine-1-Phosphate Uridyltransferase; Hemolysin Erythrocyte Lysis; 2 3-Dimethylmalate Lyase; GDP-Mannose Pyrophosphorylase; Glucose-1-Phosphate Thymidylyltransferase

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MKAIILAAGRGSRMKSLTDERPKCLVELRGKALLEWQLESLRAAGISEIAIVTGYKREWLAERDLIEFHNPRWADTNMVS
SLACAESWLQGQPCIVSYSDIFYSPDAVRSLVTNEASLAVTYDPHWLKLWTQRFGDPLLDAETFRLTDAGTLAEIGNKPQ
SVDEVQGQYMGLLRFTPQGWAEVVRLRAELTPEQRDKMHMTNTLQRVIDAGRVPVAAVAYSGEWGEVDSSEDLSAYQ

Sequences:

>Translated_237_residues
MKAIILAAGRGSRMKSLTDERPKCLVELRGKALLEWQLESLRAAGISEIAIVTGYKREWLAERDLIEFHNPRWADTNMVS
SLACAESWLQGQPCIVSYSDIFYSPDAVRSLVTNEASLAVTYDPHWLKLWTQRFGDPLLDAETFRLTDAGTLAEIGNKPQ
SVDEVQGQYMGLLRFTPQGWAEVVRLRAELTPEQRDKMHMTNTLQRVIDAGRVPVAAVAYSGEWGEVDSSEDLSAYQ
>Mature_237_residues
MKAIILAAGRGSRMKSLTDERPKCLVELRGKALLEWQLESLRAAGISEIAIVTGYKREWLAERDLIEFHNPRWADTNMVS
SLACAESWLQGQPCIVSYSDIFYSPDAVRSLVTNEASLAVTYDPHWLKLWTQRFGDPLLDAETFRLTDAGTLAEIGNKPQ
SVDEVQGQYMGLLRFTPQGWAEVVRLRAELTPEQRDKMHMTNTLQRVIDAGRVPVAAVAYSGEWGEVDSSEDLSAYQ

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1213

COG function: function code M; Predicted sugar nucleotidyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.24 [C]

Molecular weight: Translated: 26606; Mature: 26606

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIILAAGRGSRMKSLTDERPKCLVELRGKALLEWQLESLRAAGISEIAIVTGYKREWL
CCEEEEECCCCCHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHH
AERDLIEFHNPRWADTNMVSSLACAESWLQGQPCIVSYSDIFYSPDAVRSLVTNEASLAV
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHCCHHHHHHHHCCCCEEEE
TYDPHWLKLWTQRFGDPLLDAETFRLTDAGTLAEIGNKPQSVDEVQGQYMGLLRFTPQGW
EECCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHCCCCCHHHHHHHHHEEEEEECCHHH
AEVVRLRAELTPEQRDKMHMTNTLQRVIDAGRVPVAAVAYSGEWGEVDSSEDLSAYQ
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKAIILAAGRGSRMKSLTDERPKCLVELRGKALLEWQLESLRAAGISEIAIVTGYKREWL
CCEEEEECCCCCHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHH
AERDLIEFHNPRWADTNMVSSLACAESWLQGQPCIVSYSDIFYSPDAVRSLVTNEASLAV
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHCCHHHHHHHHCCCCEEEE
TYDPHWLKLWTQRFGDPLLDAETFRLTDAGTLAEIGNKPQSVDEVQGQYMGLLRFTPQGW
EECCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHCCCCCHHHHHHHHHEEEEEECCHHH
AEVVRLRAELTPEQRDKMHMTNTLQRVIDAGRVPVAAVAYSGEWGEVDSSEDLSAYQ
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTTP; D-Glucose 1-phosphate; H+ [C]

Specific reaction: dTTP + D-Glucose 1-phosphate + H+ --> dTDPglucose + Diphosphate [C]

General reaction: Nucleotidyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA