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The map label for this gene is cysC [H]

Identifier: 77461731

GI number: 77461731

Start: 6175995

End: 6176543

Strand: Direct

Name: cysC [H]

Synonym: Pfl01_5510

Alternate gene names: 77461731

Gene position: 6175995-6176543 (Clockwise)

Preceding gene: 77461730

Following gene: 77461732

Centisome position: 95.92

GC content: 59.74

Gene sequence:

>549_bases
ATGAAATGTAACCCTCACGCGCAGGTGATCTGGATTACGGGCCTTTCAGGCGCCGGCAAATCAACGCTGGCCGGTGATCT
CGTTGACCGTCTGCGCAGCCGCGGCGAATCGGTCGTGATGCTCGACGGCGACGAGCTGCGCGAGGTGTTCGGCGCCACCG
CAGCCAGCTCGCAGAACCATGGCCGCGAAGGGCGACTCGCGCTGGCCATGCAATACGCCCACCTCTGCAGAATGATCGCC
GCACAAGGCCACACCGTGGTGATCGCAACGATTTCGCTGTTTCGTGAAGTTCATGCGTGGAACCGTGCCCACCTGCCCGG
CTATTTCGAGGTTTATCTCAAAGTACCGTTAGAGGAACTCGGTCGCCGGGATCCCAAGGGCATCTACCGTCGGTTTCATG
CCGGTGAACTGCACAACGTTGCCGGTCTCGACCTGCCTGTGGATGAACCGCAGGCAGCGGACTGGCTGGTTGAATTCGAC
CCGCTGCGCTCCAGGCACGACCTGGCAGACGATCTACTCAATAAAATCAATACAAGGAATCCGGCATGA

Upstream 100 bases:

>100_bases
TTGGCAACATCAAAGAACGTGACTGAATACTTGTATCGCGTATTGAACCGGTGCAGGTTCATCACGCCAGGTATCCAAAC
CGGACACTGGTCAGAATGCT

Downstream 100 bases:

>100_bases
AAACCGAATGGGATTACACCACCCTGGCCGACGCTTACCTGAAGCGTCCTGACTACGCCGATGCTGCCATCGATGCCATG
CTCTCGATCGCAGGTGCCGA

Product: adenylylsulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MKCNPHAQVIWITGLSGAGKSTLAGDLVDRLRSRGESVVMLDGDELREVFGATAASSQNHGREGRLALAMQYAHLCRMIA
AQGHTVVIATISLFREVHAWNRAHLPGYFEVYLKVPLEELGRRDPKGIYRRFHAGELHNVAGLDLPVDEPQAADWLVEFD
PLRSRHDLADDLLNKINTRNPA

Sequences:

>Translated_182_residues
MKCNPHAQVIWITGLSGAGKSTLAGDLVDRLRSRGESVVMLDGDELREVFGATAASSQNHGREGRLALAMQYAHLCRMIA
AQGHTVVIATISLFREVHAWNRAHLPGYFEVYLKVPLEELGRRDPKGIYRRFHAGELHNVAGLDLPVDEPQAADWLVEFD
PLRSRHDLADDLLNKINTRNPA
>Mature_182_residues
MKCNPHAQVIWITGLSGAGKSTLAGDLVDRLRSRGESVVMLDGDELREVFGATAASSQNHGREGRLALAMQYAHLCRMIA
AQGHTVVIATISLFREVHAWNRAHLPGYFEVYLKVPLEELGRRDPKGIYRRFHAGELHNVAGLDLPVDEPQAADWLVEFD
PLRSRHDLADDLLNKINTRNPA

Specific function: Catalyzes the synthesis of activated sulfate [H]

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI46094058, Length=159, Percent_Identity=30.8176100628931, Blast_Score=78, Evalue=4e-15,
Organism=Homo sapiens, GI34447231, Length=153, Percent_Identity=30.718954248366, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI62912492, Length=153, Percent_Identity=30.718954248366, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1789107, Length=148, Percent_Identity=33.7837837837838, Blast_Score=79, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17542422, Length=154, Percent_Identity=29.2207792207792, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322852, Length=153, Percent_Identity=29.4117647058824, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24667040, Length=160, Percent_Identity=28.125, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI116007838, Length=160, Percent_Identity=28.125, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24667044, Length=160, Percent_Identity=28.125, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24667032, Length=160, Percent_Identity=28.125, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24667028, Length=160, Percent_Identity=28.125, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24667036, Length=160, Percent_Identity=28.125, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891 [H]

Pfam domain/function: PF01583 APS_kinase [H]

EC number: =2.7.1.25 [H]

Molecular weight: Translated: 20239; Mature: 20239

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCNPHAQVIWITGLSGAGKSTLAGDLVDRLRSRGESVVMLDGDELREVFGATAASSQNH
CCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCCC
GREGRLALAMQYAHLCRMIAAQGHTVVIATISLFREVHAWNRAHLPGYFEVYLKVPLEEL
CCCCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCCCCCCEEHEEECCHHHC
GRRDPKGIYRRFHAGELHNVAGLDLPVDEPQAADWLVEFDPLRSRHDLADDLLNKINTRN
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCC
PA
CC
>Mature Secondary Structure
MKCNPHAQVIWITGLSGAGKSTLAGDLVDRLRSRGESVVMLDGDELREVFGATAASSQNH
CCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCCC
GREGRLALAMQYAHLCRMIAAQGHTVVIATISLFREVHAWNRAHLPGYFEVYLKVPLEEL
CCCCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCCCCCCEEHEEECCHHHC
GRRDPKGIYRRFHAGELHNVAGLDLPVDEPQAADWLVEFDPLRSRHDLADDLLNKINTRN
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCC
PA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]