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The map label for this gene is xerC [H]

Identifier: 77461722

GI number: 77461722

Start: 6167295

End: 6168194

Strand: Direct

Name: xerC [H]

Synonym: Pfl01_5501

Alternate gene names: 77461722

Gene position: 6167295-6168194 (Clockwise)

Preceding gene: 77461721

Following gene: 77461723

Centisome position: 95.79

GC content: 64.22

Gene sequence:

>900_bases
ATGGAACGGCAACTGGACGCTTACTGCGAACACCTGCGCAGTGAGCGGCAGGTGTCGCCGCATACGCTGTCGGCCTACCG
GCGCGATCTCGATAAAGTCCTCGGCTGGTGCATCAAACAGAACATCGGCAGCTGGCAGGCGCTCGACATCCAGCGCCTGC
GCAGCCTGATCGCCCGCCTGCATGCCCAAGGCCAGTCCTCGCGCAGTCTGGCCCGCCTGCTCTCGGCGGTGCGCGGGCTC
TATCACTATCTGAATCGCGAATGTCTCTGCGATCACGATCCCGCAACGGGTCTCGCACCACCGAAAGGTGAACGTCGCCT
GCCGAAAACCCTCGATACCGACCGAGCGCTGCAACTGCTCGAAGGCGCAGTCGAGGACGACTTTCTGGCCCGGCGCGATC
AGGCGATTCTGGAATTGTTCTATTCCTCCGGCCTGCGGCTGTCGGAGCTGACCGGGCTCAATCTCGATCAGCTCGATCTG
GCCGACGGCATGGTCCAGGTGCTCGGCAAGGGCAGCAAGACACGCCTGCTGCCCGTCGGCAAAAAGGCTCGGGAAGCGCT
GGAGCAATGGCTGCCGCTGCGGGCGCTGACCAACCCGTCGGACGACGCCGTGTTCGTCAGCCAGCAAGGCCGCCGCCTCG
GCCCGCGAGCGATTCAGGTGCGGGTCAAACTGGCGGGCGAGCGCGAACTGGGGCAGAACCTGCACCCGCACATGCTGCGG
CACTCCTTCGCCAGCCATTTGCTCGAGTCCTCCCAGGACCTGCGTGCGGTGCAGGAACTGCTCGGCCACTCGGACATCAA
GACCACCCAGATCTATACCCACCTGGACTTCCAGCACCTGGCGGCGGTCTATGACAGCGCCCATCCACGGGCCAAACGCA
TGAAAGGCGATGATTCATGA

Upstream 100 bases:

>100_bases
ACAAGAGTTCGGTCGGCACGCTGTTCCTCAGCTACATCGCCGAAGTCATGGGTCGCGTGCTGCCACGGGTCAACAGCTCC
CTGCGCTCGGTACGCTGACC

Downstream 100 bases:

>100_bases
GCATCCAGTTGATCACCTTCGACCTCGACGACACCCTGTGGGATACCGCCCCGGTGATCGTCAGCGCAGAAGCGGTTTTG
CGCGAATGGCTGAGCGAACA

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MERQLDAYCEHLRSERQVSPHTLSAYRRDLDKVLGWCIKQNIGSWQALDIQRLRSLIARLHAQGQSSRSLARLLSAVRGL
YHYLNRECLCDHDPATGLAPPKGERRLPKTLDTDRALQLLEGAVEDDFLARRDQAILELFYSSGLRLSELTGLNLDQLDL
ADGMVQVLGKGSKTRLLPVGKKAREALEQWLPLRALTNPSDDAVFVSQQGRRLGPRAIQVRVKLAGERELGQNLHPHMLR
HSFASHLLESSQDLRAVQELLGHSDIKTTQIYTHLDFQHLAAVYDSAHPRAKRMKGDDS

Sequences:

>Translated_299_residues
MERQLDAYCEHLRSERQVSPHTLSAYRRDLDKVLGWCIKQNIGSWQALDIQRLRSLIARLHAQGQSSRSLARLLSAVRGL
YHYLNRECLCDHDPATGLAPPKGERRLPKTLDTDRALQLLEGAVEDDFLARRDQAILELFYSSGLRLSELTGLNLDQLDL
ADGMVQVLGKGSKTRLLPVGKKAREALEQWLPLRALTNPSDDAVFVSQQGRRLGPRAIQVRVKLAGERELGQNLHPHMLR
HSFASHLLESSQDLRAVQELLGHSDIKTTQIYTHLDFQHLAAVYDSAHPRAKRMKGDDS
>Mature_299_residues
MERQLDAYCEHLRSERQVSPHTLSAYRRDLDKVLGWCIKQNIGSWQALDIQRLRSLIARLHAQGQSSRSLARLLSAVRGL
YHYLNRECLCDHDPATGLAPPKGERRLPKTLDTDRALQLLEGAVEDDFLARRDQAILELFYSSGLRLSELTGLNLDQLDL
ADGMVQVLGKGSKTRLLPVGKKAREALEQWLPLRALTNPSDDAVFVSQQGRRLGPRAIQVRVKLAGERELGQNLHPHMLR
HSFASHLLESSQDLRAVQELLGHSDIKTTQIYTHLDFQHLAAVYDSAHPRAKRMKGDDS

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=292, Percent_Identity=48.2876712328767, Blast_Score=271, Evalue=4e-74,
Organism=Escherichia coli, GI1789261, Length=298, Percent_Identity=41.6107382550336, Blast_Score=195, Evalue=3e-51,
Organism=Escherichia coli, GI1790768, Length=191, Percent_Identity=31.9371727748691, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790767, Length=167, Percent_Identity=29.940119760479, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33780; Mature: 33780

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERQLDAYCEHLRSERQVSPHTLSAYRRDLDKVLGWCIKQNIGSWQALDIQRLRSLIARL
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
HAQGQSSRSLARLLSAVRGLYHYLNRECLCDHDPATGLAPPKGERRLPKTLDTDRALQLL
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
EGAVEDDFLARRDQAILELFYSSGLRLSELTGLNLDQLDLADGMVQVLGKGSKTRLLPVG
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHHCCCCCCEECCCC
KKAREALEQWLPLRALTNPSDDAVFVSQQGRRLGPRAIQVRVKLAGERELGQNLHPHMLR
HHHHHHHHHHCCHHHCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCHHHCCCCCHHHHH
HSFASHLLESSQDLRAVQELLGHSDIKTTQIYTHLDFQHLAAVYDSAHPRAKRMKGDDS
HHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHCCCCHHHCCCCCCC
>Mature Secondary Structure
MERQLDAYCEHLRSERQVSPHTLSAYRRDLDKVLGWCIKQNIGSWQALDIQRLRSLIARL
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
HAQGQSSRSLARLLSAVRGLYHYLNRECLCDHDPATGLAPPKGERRLPKTLDTDRALQLL
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
EGAVEDDFLARRDQAILELFYSSGLRLSELTGLNLDQLDLADGMVQVLGKGSKTRLLPVG
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHHCCCCCCEECCCC
KKAREALEQWLPLRALTNPSDDAVFVSQQGRRLGPRAIQVRVKLAGERELGQNLHPHMLR
HHHHHHHHHHCCHHHCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCHHHCCCCCHHHHH
HSFASHLLESSQDLRAVQELLGHSDIKTTQIYTHLDFQHLAAVYDSAHPRAKRMKGDDS
HHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9618537; 11872710 [H]