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The map label for this gene is ygjG [C]

Identifier: 77461627

GI number: 77461627

Start: 6069515

End: 6070879

Strand: Reverse

Name: ygjG [C]

Synonym: Pfl01_5406

Alternate gene names: 77461627

Gene position: 6070879-6069515 (Counterclockwise)

Preceding gene: 77461628

Following gene: 77461626

Centisome position: 94.29

GC content: 60.95

Gene sequence:

>1365_bases
ATGACCAGCAACAACCCGCAAACCCGTGAGTGGCAAGCCCTCAGCAGCGATCACCACCTGGCTCCGTTCAGCGACTTCAA
GCAGCTGAAAGAAAAAGGTCCACGGATCATCACCAACGCCAAGGGCGTGTACCTGTGGGACAGCGAGGGCAACAAGATCC
TCGATGGCATGGCGGGTCTGTGGTGTGTGGCGATCGGTTATGGACGCGACGAGCTGGCCGATGCGGCCGCCAAGCAGATG
CGCGAACTGCCTTACTACAACCTGTTCTTCCAGACCGCCCACCCGCCAGCACTGGAGTTGGCCAAGGCCATCGCCGACGT
GGCGCCGGAAGGCATGAACCACGTGTTCTTCACCGGCTCCGGCTCCGAAGGCAACGACACCATGCTGCGTATGGTTCGCC
ACTACTGGGCGATCAAGGGCCAGCCGAACAAGAAGGTCATCATCAGCCGCAAGAACGGCTACCACGGTTCCACCGTGGCC
GGCGCAAGCCTGGGCGGCATGACTTACATGCACGAACAGGGCGACCTGCCGATTCCGGGCATCGTCCACATCGCCCAGCC
GTACTGGTTCGCCGAAGGCGGCGACATGACCCCGGAAGAGTTCGGGATCTGGGCGGCCAATCAGCTGGAGGAAAAGATTC
TGGAAGTCGGCGTGGATAACGTCGGTGCCTTTATTGCCGAGCCGATCCAGGGCGCTGGCGGCGTGATCATTCCGCCGGAC
ACCTACTGGCCGCGCATCAAGGAAATCCTCGCCAAGTACGACATTCTGTTCGTGGCCGATGAAGTGATCTGCGGTTTCGG
CCGTACCGGCCAATGGTTCGGCAGCGATTTCTACGACCTCAAACCACACATGATGACCATCGCCAAAGGCCTGACGTCCG
GCTACATCCCGATGGGTGGCCTGATCGTGCGCGATGAAGTGGTGGCGGTACTCAACGAGGGCGGCGATTTCAACCACGGC
TTCACCTACTCCGGTCACCCGGTGGCGGCGGCGGTGGGTCTGGAAAACATCCGGATTCTGCGCGAAGAGAAAATCATCGA
ACGCGCCCATGAAGAAACGGCACCGTATTTGCAGAAACGTCTGCGCGAACTGAACGATCACCCGTTGGTGGGTGAAGTGC
GCGGGGTCGGTCTGCTGGGGGCCATCGAGCTGGTGCAGGACAAGGCCACTCGCAAGCGTTACGAAGGCAAGGGTGTGGGC
ATGATCTGCCGCCAGTTCTGCTTCGACAACGGGCTGATCATGCGTGCCGTGGGCGACACCATGATCATCGCGCCGCCGCT
GGTGATCAGCAAGGCGGAGATCGATGAGCTGGTGACGAAGGCACGCAAGTGCCTGGACCTGACCCTGAGTGCGTTGCAGG
GCTAA

Upstream 100 bases:

>100_bases
TGATCAGTTCCTGGGAGCGTGAGTACCTGCTCTTCGCCGTCTGATACGCCGGGCGCGGTGGCCAGCCGCCGCGCCTTCAC
CGATAACAAGGAGAATTGGC

Downstream 100 bases:

>100_bases
GTGCTAGGCTCTGAGCGATGGAGCTGTTGCGCTGTCGCTCGGAGCTGTCAGAAAGGCTGGTCTTTTCTTGAAAGACCGCC
TCGGATCTTGCCAGACTAGC

Product: putative aminotransferase

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MTSNNPQTREWQALSSDHHLAPFSDFKQLKEKGPRIITNAKGVYLWDSEGNKILDGMAGLWCVAIGYGRDELADAAAKQM
RELPYYNLFFQTAHPPALELAKAIADVAPEGMNHVFFTGSGSEGNDTMLRMVRHYWAIKGQPNKKVIISRKNGYHGSTVA
GASLGGMTYMHEQGDLPIPGIVHIAQPYWFAEGGDMTPEEFGIWAANQLEEKILEVGVDNVGAFIAEPIQGAGGVIIPPD
TYWPRIKEILAKYDILFVADEVICGFGRTGQWFGSDFYDLKPHMMTIAKGLTSGYIPMGGLIVRDEVVAVLNEGGDFNHG
FTYSGHPVAAAVGLENIRILREEKIIERAHEETAPYLQKRLRELNDHPLVGEVRGVGLLGAIELVQDKATRKRYEGKGVG
MICRQFCFDNGLIMRAVGDTMIIAPPLVISKAEIDELVTKARKCLDLTLSALQG

Sequences:

>Translated_454_residues
MTSNNPQTREWQALSSDHHLAPFSDFKQLKEKGPRIITNAKGVYLWDSEGNKILDGMAGLWCVAIGYGRDELADAAAKQM
RELPYYNLFFQTAHPPALELAKAIADVAPEGMNHVFFTGSGSEGNDTMLRMVRHYWAIKGQPNKKVIISRKNGYHGSTVA
GASLGGMTYMHEQGDLPIPGIVHIAQPYWFAEGGDMTPEEFGIWAANQLEEKILEVGVDNVGAFIAEPIQGAGGVIIPPD
TYWPRIKEILAKYDILFVADEVICGFGRTGQWFGSDFYDLKPHMMTIAKGLTSGYIPMGGLIVRDEVVAVLNEGGDFNHG
FTYSGHPVAAAVGLENIRILREEKIIERAHEETAPYLQKRLRELNDHPLVGEVRGVGLLGAIELVQDKATRKRYEGKGVG
MICRQFCFDNGLIMRAVGDTMIIAPPLVISKAEIDELVTKARKCLDLTLSALQG
>Mature_453_residues
TSNNPQTREWQALSSDHHLAPFSDFKQLKEKGPRIITNAKGVYLWDSEGNKILDGMAGLWCVAIGYGRDELADAAAKQMR
ELPYYNLFFQTAHPPALELAKAIADVAPEGMNHVFFTGSGSEGNDTMLRMVRHYWAIKGQPNKKVIISRKNGYHGSTVAG
ASLGGMTYMHEQGDLPIPGIVHIAQPYWFAEGGDMTPEEFGIWAANQLEEKILEVGVDNVGAFIAEPIQGAGGVIIPPDT
YWPRIKEILAKYDILFVADEVICGFGRTGQWFGSDFYDLKPHMMTIAKGLTSGYIPMGGLIVRDEVVAVLNEGGDFNHGF
TYSGHPVAAAVGLENIRILREEKIIERAHEETAPYLQKRLRELNDHPLVGEVRGVGLLGAIELVQDKATRKRYEGKGVGM
ICRQFCFDNGLIMRAVGDTMIIAPPLVISKAEIDELVTKARKCLDLTLSALQG

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=448, Percent_Identity=28.5714285714286, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI4557809, Length=448, Percent_Identity=26.1160714285714, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI37574042, Length=433, Percent_Identity=27.9445727482679, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI226442705, Length=434, Percent_Identity=28.3410138248848, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI24119277, Length=439, Percent_Identity=26.4236902050114, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI226442709, Length=402, Percent_Identity=28.1094527363184, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI284507298, Length=329, Percent_Identity=28.2674772036474, Blast_Score=125, Evalue=8e-29,
Organism=Escherichia coli, GI145693181, Length=403, Percent_Identity=28.287841191067, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789759, Length=406, Percent_Identity=27.8325123152709, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1786991, Length=414, Percent_Identity=26.8115942028986, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1788044, Length=402, Percent_Identity=27.6119402985075, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789016, Length=417, Percent_Identity=26.1390887290168, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1787560, Length=426, Percent_Identity=27.6995305164319, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1786349, Length=339, Percent_Identity=21.8289085545723, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI32564660, Length=435, Percent_Identity=30.3448275862069, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71992977, Length=433, Percent_Identity=27.9445727482679, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI25144271, Length=411, Percent_Identity=26.5206812652068, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI25144274, Length=295, Percent_Identity=28.8135593220339, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17541228, Length=451, Percent_Identity=22.1729490022173, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6323470, Length=456, Percent_Identity=27.4122807017544, Blast_Score=173, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6324386, Length=424, Percent_Identity=27.3584905660377, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6324432, Length=428, Percent_Identity=27.1028037383178, Blast_Score=122, Evalue=9e-29,
Organism=Saccharomyces cerevisiae, GI6321456, Length=405, Percent_Identity=25.1851851851852, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28574759, Length=445, Percent_Identity=30.3370786516854, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI161085790, Length=447, Percent_Identity=29.7539149888143, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI21357415, Length=416, Percent_Identity=28.3653846153846, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI21356575, Length=430, Percent_Identity=27.906976744186, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI281366494, Length=338, Percent_Identity=23.0769230769231, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24667139, Length=338, Percent_Identity=23.0769230769231, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24667143, Length=338, Percent_Identity=23.0769230769231, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 49986; Mature: 49855

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSNNPQTREWQALSSDHHLAPFSDFKQLKEKGPRIITNAKGVYLWDSEGNKILDGMAGL
CCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHCCCEEEECCCEEEEECCCCCCHHHHHHCE
WCVAIGYGRDELADAAAKQMRELPYYNLFFQTAHPPALELAKAIADVAPEGMNHVFFTGS
EHEEECCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEECC
GSEGNDTMLRMVRHYWAIKGQPNKKVIISRKNGYHGSTVAGASLGGMTYMHEQGDLPIPG
CCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCC
IVHIAQPYWFAEGGDMTPEEFGIWAANQLEEKILEVGVDNVGAFIAEPIQGAGGVIIPPD
CEEECCCEEECCCCCCCHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEECCC
TYWPRIKEILAKYDILFVADEVICGFGRTGQWFGSDFYDLKPHMMTIAKGLTSGYIPMGG
CCHHHHHHHHHHHHHHEEEHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
LIVRDEVVAVLNEGGDFNHGFTYSGHPVAAAVGLENIRILREEKIIERAHEETAPYLQKR
EEEHHHHHHHHHCCCCCCCCCCCCCCCEEEHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRELNDHPLVGEVRGVGLLGAIELVQDKATRKRYEGKGVGMICRQFCFDNGLIMRAVGDT
HHHCCCCCCEEHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCE
MIIAPPLVISKAEIDELVTKARKCLDLTLSALQG
EEECCCCEECHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSNNPQTREWQALSSDHHLAPFSDFKQLKEKGPRIITNAKGVYLWDSEGNKILDGMAGL
CCCCCCCCHHHHHCCCCCCCCHHHHHHHHHCCCEEEECCCEEEEECCCCCCHHHHHHCE
WCVAIGYGRDELADAAAKQMRELPYYNLFFQTAHPPALELAKAIADVAPEGMNHVFFTGS
EHEEECCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEECC
GSEGNDTMLRMVRHYWAIKGQPNKKVIISRKNGYHGSTVAGASLGGMTYMHEQGDLPIPG
CCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCC
IVHIAQPYWFAEGGDMTPEEFGIWAANQLEEKILEVGVDNVGAFIAEPIQGAGGVIIPPD
CEEECCCEEECCCCCCCHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEECCC
TYWPRIKEILAKYDILFVADEVICGFGRTGQWFGSDFYDLKPHMMTIAKGLTSGYIPMGG
CCHHHHHHHHHHHHHHEEEHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
LIVRDEVVAVLNEGGDFNHGFTYSGHPVAAAVGLENIRILREEKIIERAHEETAPYLQKR
EEEHHHHHHHHHCCCCCCCCCCCCCCCEEEHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRELNDHPLVGEVRGVGLLGAIELVQDKATRKRYEGKGVGMICRQFCFDNGLIMRAVGDT
HHHCCCCCCEEHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCE
MIIAPPLVISKAEIDELVTKARKCLDLTLSALQG
EEECCCCEECHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]