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The map label for this gene is rpiA [H]

Identifier: 77461603

GI number: 77461603

Start: 6045114

End: 6045788

Strand: Direct

Name: rpiA [H]

Synonym: Pfl01_5382

Alternate gene names: 77461603

Gene position: 6045114-6045788 (Clockwise)

Preceding gene: 77461600

Following gene: 77461608

Centisome position: 93.89

GC content: 64.15

Gene sequence:

>675_bases
ATGACCCAGGATCAACTCAAACAGGCCGTGGCCCAGGCCGCCGTCGACTTCATCCTTCCGAAACTCGACGACAAGAGCAT
CGTCGGTGTCGGCACCGGCTCCACCGCCAACTGCTTCATCGACGCCCTGGCCCAGCACAAGGGCGCGTTCGATGGCGCGG
TCGCGAGCTCCGAAGCCACCGCCGCGCGCCTCAAGGGCCACGGGATTCCGGTGTACGAGCTGAACACCGTGAGCAACCTG
GAGTTCTACGTCGACGGCGCCGATGAAAGCGACGAACACCTGAACCTGATCAAGGGCGGCGGCGCAGCCCTGACCCGCGA
GAAGATCGTCGCGGCCGTGGCCCAGACCTTCATCTGCATCGCCGACGCCAGCAAACTGGTGCCGGTGCTGGGCGCGTTCC
CGCTGCCGGTGGAAGTGATCCCGATGGCCCGCAGCCACGTGGCCCGCCAACTGGTAAAACTGGGCGGCGACCCGGTCTAC
CGCGAAGGCGTGCTGACCGACAACGGCAACATCATCCTCGACGTGCACAACCTGCAGATCACCAATCCGGTGGAGCTGGA
AGCGCAGATCAACGCGATCGTCGGCGTGGTCACCAACGGCCTGTTCGCGGCGCGTCCGGCGGATTTGTTGTTGCTGGGTA
CTTCCGAAGGTGTGAAAACACTGAAGGCTGAGTAA

Upstream 100 bases:

>100_bases
GGTTTCGGCCGGACGACCACACGAATCCAGAGGTTTTAGCCCGGCTTGAGGCTATAATGCCGGCCTTTCCGTTCTTACCT
TGCCCGCTTCCGGAGCCCGC

Downstream 100 bases:

>100_bases
GCCGAAACTGCCCGTATTTTGGTGGGCAGATGAAAAAACTGTGGGAGCCAGTTTGCTAGCTCCCACATTGTTAGATGGTG
CTGGTTAGTTCTGCGCAGGC

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MTQDQLKQAVAQAAVDFILPKLDDKSIVGVGTGSTANCFIDALAQHKGAFDGAVASSEATAARLKGHGIPVYELNTVSNL
EFYVDGADESDEHLNLIKGGGAALTREKIVAAVAQTFICIADASKLVPVLGAFPLPVEVIPMARSHVARQLVKLGGDPVY
REGVLTDNGNIILDVHNLQITNPVELEAQINAIVGVVTNGLFAARPADLLLLGTSEGVKTLKAE

Sequences:

>Translated_224_residues
MTQDQLKQAVAQAAVDFILPKLDDKSIVGVGTGSTANCFIDALAQHKGAFDGAVASSEATAARLKGHGIPVYELNTVSNL
EFYVDGADESDEHLNLIKGGGAALTREKIVAAVAQTFICIADASKLVPVLGAFPLPVEVIPMARSHVARQLVKLGGDPVY
REGVLTDNGNIILDVHNLQITNPVELEAQINAIVGVVTNGLFAARPADLLLLGTSEGVKTLKAE
>Mature_223_residues
TQDQLKQAVAQAAVDFILPKLDDKSIVGVGTGSTANCFIDALAQHKGAFDGAVASSEATAARLKGHGIPVYELNTVSNLE
FYVDGADESDEHLNLIKGGGAALTREKIVAAVAQTFICIADASKLVPVLGAFPLPVEVIPMARSHVARQLVKLGGDPVYR
EGVLTDNGNIILDVHNLQITNPVELEAQINAIVGVVTNGLFAARPADLLLLGTSEGVKTLKAE

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=234, Percent_Identity=34.1880341880342, Blast_Score=96, Evalue=4e-20,
Organism=Escherichia coli, GI1789280, Length=221, Percent_Identity=64.2533936651584, Blast_Score=280, Evalue=8e-77,
Organism=Caenorhabditis elegans, GI17551758, Length=206, Percent_Identity=33.495145631068, Blast_Score=90, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6324669, Length=232, Percent_Identity=34.9137931034483, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI281364072, Length=197, Percent_Identity=32.48730964467, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 23431; Mature: 23300

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDQLKQAVAQAAVDFILPKLDDKSIVGVGTGSTANCFIDALAQHKGAFDGAVASSEAT
CCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCHH
AARLKGHGIPVYELNTVSNLEFYVDGADESDEHLNLIKGGGAALTREKIVAAVAQTFICI
HHHHCCCCCCEEEECCCCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
ADASKLVPVLGAFPLPVEVIPMARSHVARQLVKLGGDPVYREGVLTDNGNIILDVHNLQI
HCCHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCEEECCCCEEEEEECEEE
TNPVELEAQINAIVGVVTNGLFAARPADLLLLGTSEGVKTLKAE
CCCEEEHHHHHHHHHHHHCCEEECCCCCEEEEECCCCCEEECCC
>Mature Secondary Structure 
TQDQLKQAVAQAAVDFILPKLDDKSIVGVGTGSTANCFIDALAQHKGAFDGAVASSEAT
CHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCHH
AARLKGHGIPVYELNTVSNLEFYVDGADESDEHLNLIKGGGAALTREKIVAAVAQTFICI
HHHHCCCCCCEEEECCCCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
ADASKLVPVLGAFPLPVEVIPMARSHVARQLVKLGGDPVYREGVLTDNGNIILDVHNLQI
HCCHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCEEECCCCEEEEEECEEE
TNPVELEAQINAIVGVVTNGLFAARPADLLLLGTSEGVKTLKAE
CCCEEEHHHHHHHHHHHHCCEEECCCCCEEEEECCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA