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The map label for this gene is yggW [H]

Identifier: 77461548

GI number: 77461548

Start: 5988559

End: 5989764

Strand: Direct

Name: yggW [H]

Synonym: Pfl01_5327

Alternate gene names: 77461548

Gene position: 5988559-5989764 (Clockwise)

Preceding gene: 77461547

Following gene: 77461549

Centisome position: 93.01

GC content: 63.1

Gene sequence:

>1206_bases
ATGACCGATAGTTCCTCCGCGTCGTCGCTGATTATCGGCGGCGCCGCCTCCTCGCCTCGGGCGCCGTTGCCGACGCTGCC
GCCCCTGGCGCTGTACATCCACATCCCGTGGTGTGTGCGCAAATGCCCCTATTGCGACTTCAACTCCCACACCGCCAGCC
CGGTGCTGCCGGAGCAGGAGTATGTCGACGCGATGCTGGCCGACCTCGATCAGGATCTGCACGCGGTGTACGGCCGTGAG
TTGAGTTCGATCTTCTTTGGCGGCGGCACGCCGAGCCTGTTCAGTGCCGAAGCCCTTGGTCGCTTGCTGGAAGGCGTCAA
ACAACGCATCCCGTTTGCCGATGACATCGAAATCACCCTGGAAGCCAACCCCGGGACTTTCGAGCAAGAGAAGTTCGTTG
CCTACCGCAAGCTGGGAATCAATCGCCTGTCGATCGGTATCCAGAGCTTCCAGCAGGAAAAGCTCAAGGCCCTCGGCCGA
ATCCACAACGGCGATGAAGCGGTACGCGCCGCCGGCATGGCGCGCCAGGCCGGGTTCGATAACTTCAACCTCGACTTGAT
GCACGGCTTGCCGGACCAGTCACTGGACGATGCCCTGAGCGATCTGCGCCAGGCGATCGAACTGAAGCCGACGCATATTT
CCTGGTATCAGCTGACACTGGAGCCGAACACCGTGTTCTGGAACCAGCCGCCGGTGCTGCCGGAAGACGACACGCTGTGG
GACATTCAAGAGGCCGGGCAGGCGCTGCTGGCCGAGCACGGTTACGCGCAGTACGAAGTTTCGGCCTACGCCCAACCGGG
TCGACCGGCGCGGCACAACCTCAATTACTGGAGCTTCGGCGACTTCATCGGCATCGGCGCCGGCGCCCACGGCAAGCTCA
GTCACCCGGACGGGCGCATCGTGCGTACCTGGAAGACACGCCTGCCGAAGGACTACCTCAACCCGGCCAAAAGCTTCCAG
GCCGGCGAGAAAGCCCTGACCAACGACGAGATGCCGTTCGAGTTCCTGATGAACGCCCTGCGCCTCACCGCCGGCGTCGA
ATCGCGCCTGTACCCGGAGCGCACCGGCCTGTCGCTGGACACGCTTGCCGAAGGTCGGCGCGAGGCCGAACAAAGCGGTC
TGTTGCAGGTCGAACCGTCACGCCTGGCGACCACAGAGCGCGGACAGCTGTTCCTCAACGACTTGCTGCAACAATTTCTG
AACTGA

Upstream 100 bases:

>100_bases
AGCGTAACGTGTCCAGCGCCGAACTGAGCCCGAGCGACAAGAACCAGATCAGTCACCGCGCCCGTGCAATGGATCTGCTG
CGCCAGCGTCTGGGCTTGAA

Downstream 100 bases:

>100_bases
CTTCAGTCCCAAGGGAAAACGCATGGATTTGATACTCGACCTGCTCGCCACCGTCTCCCGCTGGAGCCGCAGCAACCTCT
CGGAAATCGCCCTGGCGCTG

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MTDSSSASSLIIGGAASSPRAPLPTLPPLALYIHIPWCVRKCPYCDFNSHTASPVLPEQEYVDAMLADLDQDLHAVYGRE
LSSIFFGGGTPSLFSAEALGRLLEGVKQRIPFADDIEITLEANPGTFEQEKFVAYRKLGINRLSIGIQSFQQEKLKALGR
IHNGDEAVRAAGMARQAGFDNFNLDLMHGLPDQSLDDALSDLRQAIELKPTHISWYQLTLEPNTVFWNQPPVLPEDDTLW
DIQEAGQALLAEHGYAQYEVSAYAQPGRPARHNLNYWSFGDFIGIGAGAHGKLSHPDGRIVRTWKTRLPKDYLNPAKSFQ
AGEKALTNDEMPFEFLMNALRLTAGVESRLYPERTGLSLDTLAEGRREAEQSGLLQVEPSRLATTERGQLFLNDLLQQFL
N

Sequences:

>Translated_401_residues
MTDSSSASSLIIGGAASSPRAPLPTLPPLALYIHIPWCVRKCPYCDFNSHTASPVLPEQEYVDAMLADLDQDLHAVYGRE
LSSIFFGGGTPSLFSAEALGRLLEGVKQRIPFADDIEITLEANPGTFEQEKFVAYRKLGINRLSIGIQSFQQEKLKALGR
IHNGDEAVRAAGMARQAGFDNFNLDLMHGLPDQSLDDALSDLRQAIELKPTHISWYQLTLEPNTVFWNQPPVLPEDDTLW
DIQEAGQALLAEHGYAQYEVSAYAQPGRPARHNLNYWSFGDFIGIGAGAHGKLSHPDGRIVRTWKTRLPKDYLNPAKSFQ
AGEKALTNDEMPFEFLMNALRLTAGVESRLYPERTGLSLDTLAEGRREAEQSGLLQVEPSRLATTERGQLFLNDLLQQFL
N
>Mature_400_residues
TDSSSASSLIIGGAASSPRAPLPTLPPLALYIHIPWCVRKCPYCDFNSHTASPVLPEQEYVDAMLADLDQDLHAVYGREL
SSIFFGGGTPSLFSAEALGRLLEGVKQRIPFADDIEITLEANPGTFEQEKFVAYRKLGINRLSIGIQSFQQEKLKALGRI
HNGDEAVRAAGMARQAGFDNFNLDLMHGLPDQSLDDALSDLRQAIELKPTHISWYQLTLEPNTVFWNQPPVLPEDDTLWD
IQEAGQALLAEHGYAQYEVSAYAQPGRPARHNLNYWSFGDFIGIGAGAHGKLSHPDGRIVRTWKTRLPKDYLNPAKSFQA
GEKALTNDEMPFEFLMNALRLTAGVESRLYPERTGLSLDTLAEGRREAEQSGLLQVEPSRLATTERGQLFLNDLLQQFLN

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=322, Percent_Identity=34.7826086956522, Blast_Score=184, Evalue=1e-46,
Organism=Escherichia coli, GI1789325, Length=375, Percent_Identity=56, Blast_Score=431, Evalue=1e-122,
Organism=Escherichia coli, GI87082341, Length=278, Percent_Identity=28.7769784172662, Blast_Score=124, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 44480; Mature: 44348

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSSSASSLIIGGAASSPRAPLPTLPPLALYIHIPWCVRKCPYCDFNSHTASPVLPEQE
CCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCCHH
YVDAMLADLDQDLHAVYGRELSSIFFGGGTPSLFSAEALGRLLEGVKQRIPFADDIEITL
HHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEE
EANPGTFEQEKFVAYRKLGINRLSIGIQSFQQEKLKALGRIHNGDEAVRAAGMARQAGFD
ECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
NFNLDLMHGLPDQSLDDALSDLRQAIELKPTHISWYQLTLEPNTVFWNQPPVLPEDDTLW
CCCCHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCEEEECCCCCCCCCCCCH
DIQEAGQALLAEHGYAQYEVSAYAQPGRPARHNLNYWSFGDFIGIGAGAHGKLSHPDGRI
HHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCEECCCEEEECCCCCCCCCCCCCCE
VRTWKTRLPKDYLNPAKSFQAGEKALTNDEMPFEFLMNALRLTAGVESRLYPERTGLSLD
EEHHHHHCCHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHCCCHHCCCCHH
TLAEGRREAEQSGLLQVEPSRLATTERGQLFLNDLLQQFLN
HHHHHHHHHHHCCCEEECHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TDSSSASSLIIGGAASSPRAPLPTLPPLALYIHIPWCVRKCPYCDFNSHTASPVLPEQE
CCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCCHH
YVDAMLADLDQDLHAVYGRELSSIFFGGGTPSLFSAEALGRLLEGVKQRIPFADDIEITL
HHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEE
EANPGTFEQEKFVAYRKLGINRLSIGIQSFQQEKLKALGRIHNGDEAVRAAGMARQAGFD
ECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
NFNLDLMHGLPDQSLDDALSDLRQAIELKPTHISWYQLTLEPNTVFWNQPPVLPEDDTLW
CCCCHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCEEEECCCCCCCCCCCCH
DIQEAGQALLAEHGYAQYEVSAYAQPGRPARHNLNYWSFGDFIGIGAGAHGKLSHPDGRI
HHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCEECCCEEEECCCCCCCCCCCCCCE
VRTWKTRLPKDYLNPAKSFQAGEKALTNDEMPFEFLMNALRLTAGVESRLYPERTGLSLD
EEHHHHHCCHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHCCCHHCCCCHH
TLAEGRREAEQSGLLQVEPSRLATTERGQLFLNDLLQQFLN
HHHHHHHHHHHCCCEEECHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]