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The map label for this gene is pyrR [H]

Identifier: 77461534

GI number: 77461534

Start: 5977981

End: 5978484

Strand: Direct

Name: pyrR [H]

Synonym: Pfl01_5313

Alternate gene names: 77461534

Gene position: 5977981-5978484 (Clockwise)

Preceding gene: 77461533

Following gene: 77461535

Centisome position: 92.85

GC content: 66.67

Gene sequence:

>504_bases
ATGAGCCTGCCCAATCCCGCCGATCTGATCAGCCAGATGGCGACCCGCCTCAAGGCGCACCTTGCCCAGCGTAATATCAG
CGAACCGCGTTACATCGGCATCCGCACCGGCGGCGTCTGGGTCGCCCAGGCCCTGCTCGCAGAGCTGGGTAGCGACGCGC
CATTGGGCACGCTGGATGTTTCCTTCTACCGCGACGACTTCAGCCAGAACGGCCTGCACCCGCAGGTGCGCCCGTCCGCC
CTGCCCTTCGAAATCGAAGGCCAGCATCTGGTGCTGATCGACGACGTACTGATGAGCGGCCGGACCATCCGCGCCGCCAT
GAACGAACTGTTCGACTACGGCCGCCCGGCCAGCGTGACGCTGGTCTGCCTGCTGGACCTGGATGCCGGCGAACTGCCGA
TCCGCCCGAACGTGGTCGGCGCGACCCTGTCGCTGGCCGCCCACGAGCGGGTCAAGCTGTCCGGGCCGGAGCTGGCCCTC
GAACTGCAAGACCTTGCCCTTTAA

Upstream 100 bases:

>100_bases
CGCACTATTTGAATCCTGACAAGCGCTACGGCGCTTTTCTTTTGGTTACAACCCGAGCCCCGGTTCGCGAGAACCGGCTC
GACCCCGAGAAGGAGCAACC

Downstream 100 bases:

>100_bases
TCCGCCCTATTGAGAGTCCCCCTCGCGATGACGCCTCTAGATACCAAGCGCCCGCTGCAGCTCAATGATCAGGGCCAGCT
GCGCCACTTCCTCTCGCTCG

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 167; Mature: 166

Protein sequence:

>167_residues
MSLPNPADLISQMATRLKAHLAQRNISEPRYIGIRTGGVWVAQALLAELGSDAPLGTLDVSFYRDDFSQNGLHPQVRPSA
LPFEIEGQHLVLIDDVLMSGRTIRAAMNELFDYGRPASVTLVCLLDLDAGELPIRPNVVGATLSLAAHERVKLSGPELAL
ELQDLAL

Sequences:

>Translated_167_residues
MSLPNPADLISQMATRLKAHLAQRNISEPRYIGIRTGGVWVAQALLAELGSDAPLGTLDVSFYRDDFSQNGLHPQVRPSA
LPFEIEGQHLVLIDDVLMSGRTIRAAMNELFDYGRPASVTLVCLLDLDAGELPIRPNVVGATLSLAAHERVKLSGPELAL
ELQDLAL
>Mature_166_residues
SLPNPADLISQMATRLKAHLAQRNISEPRYIGIRTGGVWVAQALLAELGSDAPLGTLDVSFYRDDFSQNGLHPQVRPSAL
PFEIEGQHLVLIDDVLMSGRTIRAAMNELFDYGRPASVTLVCLLDLDAGELPIRPNVVGATLSLAAHERVKLSGPELALE
LQDLAL

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 18090; Mature: 17959

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPNPADLISQMATRLKAHLAQRNISEPRYIGIRTGGVWVAQALLAELGSDAPLGTLDV
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCEEEH
SFYRDDFSQNGLHPQVRPSALPFEIEGQHLVLIDDVLMSGRTIRAAMNELFDYGRPASVT
HEECCCCCCCCCCCCCCCCCCCEEECCCEEEEEEHHHHCCCHHHHHHHHHHHCCCCCCEE
LVCLLDLDAGELPIRPNVVGATLSLAAHERVKLSGPELALELQDLAL
EEEEEECCCCCCCCCCCCCCCEEEHHHCCEEEECCCCEEEEEHHHCC
>Mature Secondary Structure 
SLPNPADLISQMATRLKAHLAQRNISEPRYIGIRTGGVWVAQALLAELGSDAPLGTLDV
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCEEEH
SFYRDDFSQNGLHPQVRPSALPFEIEGQHLVLIDDVLMSGRTIRAAMNELFDYGRPASVT
HEECCCCCCCCCCCCCCCCCCCEEECCCEEEEEEHHHHCCCHHHHHHHHHHHCCCCCCEE
LVCLLDLDAGELPIRPNVVGATLSLAAHERVKLSGPELALELQDLAL
EEEEEECCCCCCCCCCCCCCCEEEHHHCCEEEECCCCEEEEEHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA