Click here to switch to the map view.

The map label for this gene is fabD [H]

Identifier: 77461517

GI number: 77461517

Start: 5958202

End: 5959122

Strand: Reverse

Name: fabD [H]

Synonym: Pfl01_5296

Alternate gene names: 77461517

Gene position: 5959122-5958202 (Counterclockwise)

Preceding gene: 77461518

Following gene: 77461516

Centisome position: 92.56

GC content: 64.06

Gene sequence:

>921_bases
GTGAGCAGTCTGCTGGTGTTTCCCGGTCAGGGCGCGCAACAGCCCGGCATGCTTCAGCGTTTGCCTCGGGAAACGCTGAT
CGAGGCCAGCGACAGCCTCGGTGAAGATGTCTTGCAGTTGGATTCCAGCGAAGCGTTGCGCAGCACGCGGGCGGTTCAGC
TCTGTCTGTTGATCGCAGGGGTCGCAGCCTCGCGGCGATTGTTGCAGGACGGACTCACAGCGGACTACGTCGCCGGCCTG
TCCATCGGTGCCTACCCGGCAGCGGTGGTTGCCGGAGCCTTGAGCTTCAGCGATGCGCTGCATCTGGTCAGCCTGCGCGG
CGAGCTGATGCAGCAGGCTTATCCACAGGGCTTCGGCATGACCGCGATCATCGGCCTGCAATTATCCACCGTCGAAACGC
TGCTGGCGCAGGTGCATGGCGCAGAAACGCCGGTATACCTGGCCAACATCAACGCCGATAACCAGGTGGTGATTGCCGGC
AGCGACAAGGCGATGCAAGCGGTCGCCGAGTTGGCACGCGCTCGTGGCGCCGGTCTGGCAAAACGGCTGGCGGTCAGCGT
GCCGTCGCACTGCCCGTTGCTGGATGAACACGCGCAAACCCTCGCCGAAGCGTTCACCAGGGTTGAACTGAAATCACCAA
AAATCGCTTACCTGAGCGGCAGTCGCGCCAGGCCTGTGACCCAGGTAGAAGCGCTGCGCGACGATCTCGCCTTCAACATG
TGCCGCGTGGTGGACTGGCGCGGCACCGTGCAAAGCGCTTACGAGCGCGGCGTACGTTTACAGATCGAACTGCCGCCCGG
TGCGGTGCTGACCGGGCTGGCGCGCCGGGTGTTTGAACAGGGGACTGTCGCTGCCTTCGACAGTGCCCGGCTCGACACCT
TGCAGGCGCTGTTGCGTGAAGAGGAGGGCCGACGACCCTAG

Upstream 100 bases:

>100_bases
CCCTGCGCGAATGGGCCGGGAACGCTTCGCGGGTGCTGTTGAAAAATGCCCGTGAAGCCTGTCTGGTGTCTGATCCGTGG
AACCCGCAGGAGCAGGCAGC

Downstream 100 bases:

>100_bases
ACCACCGACTCAGGCTTCGAACAACAAAAACAACATTCGACGATGCACTTTGAGGACTACAACAATGATTATTTACGGTG
TGGCGCTGCTGGCGATCTGT

Product: acyl-carrier-protein S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSSLLVFPGQGAQQPGMLQRLPRETLIEASDSLGEDVLQLDSSEALRSTRAVQLCLLIAGVAASRRLLQDGLTADYVAGL
SIGAYPAAVVAGALSFSDALHLVSLRGELMQQAYPQGFGMTAIIGLQLSTVETLLAQVHGAETPVYLANINADNQVVIAG
SDKAMQAVAELARARGAGLAKRLAVSVPSHCPLLDEHAQTLAEAFTRVELKSPKIAYLSGSRARPVTQVEALRDDLAFNM
CRVVDWRGTVQSAYERGVRLQIELPPGAVLTGLARRVFEQGTVAAFDSARLDTLQALLREEEGRRP

Sequences:

>Translated_306_residues
MSSLLVFPGQGAQQPGMLQRLPRETLIEASDSLGEDVLQLDSSEALRSTRAVQLCLLIAGVAASRRLLQDGLTADYVAGL
SIGAYPAAVVAGALSFSDALHLVSLRGELMQQAYPQGFGMTAIIGLQLSTVETLLAQVHGAETPVYLANINADNQVVIAG
SDKAMQAVAELARARGAGLAKRLAVSVPSHCPLLDEHAQTLAEAFTRVELKSPKIAYLSGSRARPVTQVEALRDDLAFNM
CRVVDWRGTVQSAYERGVRLQIELPPGAVLTGLARRVFEQGTVAAFDSARLDTLQALLREEEGRRP
>Mature_305_residues
SSLLVFPGQGAQQPGMLQRLPRETLIEASDSLGEDVLQLDSSEALRSTRAVQLCLLIAGVAASRRLLQDGLTADYVAGLS
IGAYPAAVVAGALSFSDALHLVSLRGELMQQAYPQGFGMTAIIGLQLSTVETLLAQVHGAETPVYLANINADNQVVIAGS
DKAMQAVAELARARGAGLAKRLAVSVPSHCPLLDEHAQTLAEAFTRVELKSPKIAYLSGSRARPVTQVEALRDDLAFNMC
RVVDWRGTVQSAYERGVRLQIELPPGAVLTGLARRVFEQGTVAAFDSARLDTLQALLREEEGRRP

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=322, Percent_Identity=29.8136645962733, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1787334, Length=294, Percent_Identity=36.734693877551, Blast_Score=151, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI17550940, Length=296, Percent_Identity=24.6621621621622, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI71984332, Length=275, Percent_Identity=28.3636363636364, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24665753, Length=313, Percent_Identity=29.3929712460064, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32653; Mature: 32522

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLLVFPGQGAQQPGMLQRLPRETLIEASDSLGEDVLQLDSSEALRSTRAVQLCLLIAG
CCCEEEECCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
VAASRRLLQDGLTADYVAGLSIGAYPAAVVAGALSFSDALHLVSLRGELMQQAYPQGFGM
HHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TAIIGLQLSTVETLLAQVHGAETPVYLANINADNQVVIAGSDKAMQAVAELARARGAGLA
HHEEHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHCCCHH
KRLAVSVPSHCPLLDEHAQTLAEAFTRVELKSPKIAYLSGSRARPVTQVEALRDDLAFNM
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
CRVVDWRGTVQSAYERGVRLQIELPPGAVLTGLARRVFEQGTVAAFDSARLDTLQALLRE
HHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHH
EEGRRP
HHCCCC
>Mature Secondary Structure 
SSLLVFPGQGAQQPGMLQRLPRETLIEASDSLGEDVLQLDSSEALRSTRAVQLCLLIAG
CCEEEECCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
VAASRRLLQDGLTADYVAGLSIGAYPAAVVAGALSFSDALHLVSLRGELMQQAYPQGFGM
HHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TAIIGLQLSTVETLLAQVHGAETPVYLANINADNQVVIAGSDKAMQAVAELARARGAGLA
HHEEHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHCCCHH
KRLAVSVPSHCPLLDEHAQTLAEAFTRVELKSPKIAYLSGSRARPVTQVEALRDDLAFNM
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
CRVVDWRGTVQSAYERGVRLQIELPPGAVLTGLARRVFEQGTVAAFDSARLDTLQALLRE
HHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHH
EEGRRP
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]