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The map label for this gene is mauR [H]

Identifier: 77461514

GI number: 77461514

Start: 5955997

End: 5956914

Strand: Direct

Name: mauR [H]

Synonym: Pfl01_5293

Alternate gene names: 77461514

Gene position: 5955997-5956914 (Clockwise)

Preceding gene: 77461512

Following gene: 77461530

Centisome position: 92.51

GC content: 60.68

Gene sequence:

>918_bases
ATGCTGATCGACGAAGAGTTGACCCTGAAGAAACTCGAGGTGTTCCTCGCCTTCATGCGTACCGGCAACCTCGCCCGCGC
CGCCGCCGAGCTGCAGACCAGCAACGTTAGCGTGCACCGCGCGATCCATTCGCTGGAAAGCGCCCTGCGCTGTCCGCTGT
TCAAGCACGAAGGGCGCAACCTGACGCCGCTGGAAAGCGCCTACGTGCTCGAGGAGCGGGCGCAGAAGCTGATTCAGGAC
GTGGTCGAAAGCGTACGCCTGACCCGCGAAGCCGCCGGGTTCTCGGCTGAACGCTTCAAGCTCGGCTCGCTGTATTCGCT
GACGGTGAAAACCGTGCCGCAGCTGATCATGGGCCTGAAGATCCGCCGCAGCGAACTCAATATCGACCTGATCCTCGGCT
CGAACATCGACCTGCTCTACAAGCTGAAAAACATGGAAGTCGACGCGATCCTGGTGTCGCTGGACGAAACCGTCAACGAC
CCGGACTGCGAGCAGATTCCGCTGTTTTCCGACGACATCTTCCTCGCCACCCCGGCGGATTCGCGTTTCGCGCAGCGCAG
CGAAGTGGACCTGGCCGAGGTGCGCGACGAAACCTTCATCACCCTGACCCAAGGCTTCGCCACTCATCAGGACGGTATTC
GGGTGTTCAGGCAGGCGGGGTTCGAGCCGAAGGTGGCGATGCAGGTCAACGACATCTTCACCCTGCTGAGCATGGTCAGC
TCCGGGGTCGGTTATGCGTTGCTGCCGGGGAGGATTGCGGCGGTGTACGAGAACCGGGTGAAGCTGATTCCGTTGCAGGA
GAAATACCGGTTGCAGCAGCACATCGGGGTGGTGTTTTTGAAGGCTAAAGAGCGGGATCCGAATCTGCTGGCGTTGTTGG
CGGAGTGTCGGATGTATGCCAATCGCCAGTCCACCTAA

Upstream 100 bases:

>100_bases
CGGGCCTTGAGCGTAAAAGCGCAATGTTTCCGTTCAACACGGGCCTGCACCTGTCCTGATATTTGGGCACAATCGAGCGA
TACCAAGAAGAGTCCGCGCC

Downstream 100 bases:

>100_bases
CGATCGTTCCCACGCTCAGCGTGGGAACGAGCTTCAGAACCTAGCCAACGATTCCGCGAACAATGAAGAACAGCAGCGAA
GGCCCAAGCAGGCAGCCAAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MLIDEELTLKKLEVFLAFMRTGNLARAAAELQTSNVSVHRAIHSLESALRCPLFKHEGRNLTPLESAYVLEERAQKLIQD
VVESVRLTREAAGFSAERFKLGSLYSLTVKTVPQLIMGLKIRRSELNIDLILGSNIDLLYKLKNMEVDAILVSLDETVND
PDCEQIPLFSDDIFLATPADSRFAQRSEVDLAEVRDETFITLTQGFATHQDGIRVFRQAGFEPKVAMQVNDIFTLLSMVS
SGVGYALLPGRIAAVYENRVKLIPLQEKYRLQQHIGVVFLKAKERDPNLLALLAECRMYANRQST

Sequences:

>Translated_305_residues
MLIDEELTLKKLEVFLAFMRTGNLARAAAELQTSNVSVHRAIHSLESALRCPLFKHEGRNLTPLESAYVLEERAQKLIQD
VVESVRLTREAAGFSAERFKLGSLYSLTVKTVPQLIMGLKIRRSELNIDLILGSNIDLLYKLKNMEVDAILVSLDETVND
PDCEQIPLFSDDIFLATPADSRFAQRSEVDLAEVRDETFITLTQGFATHQDGIRVFRQAGFEPKVAMQVNDIFTLLSMVS
SGVGYALLPGRIAAVYENRVKLIPLQEKYRLQQHIGVVFLKAKERDPNLLALLAECRMYANRQST
>Mature_305_residues
MLIDEELTLKKLEVFLAFMRTGNLARAAAELQTSNVSVHRAIHSLESALRCPLFKHEGRNLTPLESAYVLEERAQKLIQD
VVESVRLTREAAGFSAERFKLGSLYSLTVKTVPQLIMGLKIRRSELNIDLILGSNIDLLYKLKNMEVDAILVSLDETVND
PDCEQIPLFSDDIFLATPADSRFAQRSEVDLAEVRDETFITLTQGFATHQDGIRVFRQAGFEPKVAMQVNDIFTLLSMVS
SGVGYALLPGRIAAVYENRVKLIPLQEKYRLQQHIGVVFLKAKERDPNLLALLAECRMYANRQST

Specific function: Transcriptional regulator of the mau genes for malonate utilization [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=249, Percent_Identity=23.6947791164659, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI2367136, Length=290, Percent_Identity=25.1724137931034, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788887, Length=246, Percent_Identity=21.5447154471545, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34340; Mature: 34340

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIDEELTLKKLEVFLAFMRTGNLARAAAELQTSNVSVHRAIHSLESALRCPLFKHEGRN
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHCCCCC
LTPLESAYVLEERAQKLIQDVVESVRLTREAAGFSAERFKLGSLYSLTVKTVPQLIMGLK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEECCCEEEHHHHHHHHHHHCCE
IRRSELNIDLILGSNIDLLYKLKNMEVDAILVSLDETVNDPDCEQIPLFSDDIFLATPAD
EEECCCCEEEEECCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCC
SRFAQRSEVDLAEVRDETFITLTQGFATHQDGIRVFRQAGFEPKVAMQVNDIFTLLSMVS
HHHHHHCCCCHHHHCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHH
SGVGYALLPGRIAAVYENRVKLIPLQEKYRLQQHIGVVFLKAKERDPNLLALLAECRMYA
CCCCEEECCCHHEEEECCCEEEEECHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHH
NRQST
CCCCC
>Mature Secondary Structure
MLIDEELTLKKLEVFLAFMRTGNLARAAAELQTSNVSVHRAIHSLESALRCPLFKHEGRN
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHCCCCC
LTPLESAYVLEERAQKLIQDVVESVRLTREAAGFSAERFKLGSLYSLTVKTVPQLIMGLK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEECCCEEEHHHHHHHHHHHCCE
IRRSELNIDLILGSNIDLLYKLKNMEVDAILVSLDETVNDPDCEQIPLFSDDIFLATPAD
EEECCCCEEEEECCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCC
SRFAQRSEVDLAEVRDETFITLTQGFATHQDGIRVFRQAGFEPKVAMQVNDIFTLLSMVS
HHHHHHCCCCHHHHCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHH
SGVGYALLPGRIAAVYENRVKLIPLQEKYRLQQHIGVVFLKAKERDPNLLALLAECRMYA
CCCCEEECCCHHEEEECCCEEEEECHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHH
NRQST
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA