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The map label for this gene is yciR [C]

Identifier: 77461476

GI number: 77461476

Start: 5915751

End: 5917874

Strand: Reverse

Name: yciR [C]

Synonym: Pfl01_5255

Alternate gene names: 77461476

Gene position: 5917874-5915751 (Counterclockwise)

Preceding gene: 77461480

Following gene: 77461475

Centisome position: 91.92

GC content: 60.88

Gene sequence:

>2124_bases
ATGGAATGCGCGCAACCCCAGCCAGGTGAAGGCAGCTCAGTCCTTTTGATCGTTGATGACTACCCTGAAAATCTGATCAG
CATGCGCGCATTGCTGCAGCGCCAGGACTGGCAGGTGATTACCGCGGCTTCCGGTTTCGAAGCCCTCAGTCTGCTGCTCG
AACACGACGTTGATCTGGTGTTGCTGGATGTGCAGATGCCGGGCATGGACGGCTTCGAAGTCGCGCGCCTGATGCGCGGC
AGTCAGCGCACGCGCCTGACCCCGATCATTTTCCTCACCGCCAACGAGCAGTCCCAGGACGCCGTGATCAAGGGCTACGC
CAGTGGTGCGGTGGATTATCTGTTCAAACCGTTCGATCCGCAGATTCTCAAGCCCAAAGTCCAGGCGCTGCTCGAACACC
AGCGCAATCGCCGGGCCTTGCAGCGTTTGAGTCAGGATCTGGAATCGGCGCGGGCCTTCAATGCTTCGGTGCTGGACAAC
GCTGCCGAAGGCATTCTGGTGTTGGGCGAGGATGGCTTGATTCGCTTCGCCAACCCGGCGATTTCCCGGCTGCTCAATGC
GCCGGTGAAGGAACTGGAAGGGCAGGAGTTTCTTGATTTCCTGCAGAAACCGCACATTCCGCTGTGGGCCGATTCCGAGT
TTTATGCCAGTTACAAACGTGGCGAGACGTTGCGCTTACACGACGCGTTGCTGCGTACCGCGCCGGGCCAGCAAGTGCCG
GTGGCCTTGTCCTGCGCGCCGCTGCCGAGTGAACAGCACGCGATGGTGGTGACGGTGCTGGACATGTCGGTGGTGCGCCA
TCTGCATCAACAGCTGGAATTTCAGGCGGTCACCGACCCGCTGACCGGGCTGCTCAATCGCCGGGGTTTCTACCAGACTG
TGGAAAACCTGCTGCTGCGCGGCGAGCGCACGGACAGCAGTTGGGTGTTGATGTACCTCGATCTCGACGGCTTCAAAAGG
GTCAACGATTCCCTCGGCCATGATGCCGGGGACCGGGTGTTGCGCTGGGTCTCCGAACAATTGAAAGCCTGCCTGCGGCC
ATTCGACATTCTGGCGCGGATGGGCGGCGATGAGTTCACCGCGCTGCTGGATCTGGAATTCCCCGAACAAGCGGCGAAGA
TTGCTGAAAAACTCATCGAGCGGGTGTCGATCTGTCAGCAGATCGAAGGCCTCGATATCGCTCTGGGTGCAAGTATCGGC
ATCGCCACCTACCCGGATTGCGGCAACAACCTCGATGGTTTGCTGCGCGCCTCGGACATCGCCATGTACGAAGCCAAGCG
CGCGGGGCGGCAGCAATATCGCTTCTACGATCATGAAATGAACGGCCGCGCGCGCTCGCGGTTGATGCTGGAAGAGAGCG
TGCGCAACGCCATCGAGAACCGCGATTTCAATCTGGTGTATCAGCCGCAGGTGGCGATTGGCGACGGCCGGATTCGAGGT
TTCGAGGCGCTGCTGCGCTGGCAGCACCCGAGCGTCGGCGATGTGCCGCCGGGGCTATTCCTGCCGTTGCTGGAAGAGGC
AACGTTGATCAGCCGGCTCGGCAGCTGGATCTATCACCGCAGCGCCGGGCAGCGTAAGGCGTGGGAATCCGAGTTCTCCC
AGGATCTGGTGATCGGCGTGAGCCTGAGCAACACCCAGTTCGGCCTGCCGAATCTGGTCACCGAATTGCGCCAGGTGCTG
GAGCGCCATGGATTGCAGCCGCACCAGATGGAAGTGGAAGTGACCGAAGAGGCGCTGACGATCAACCCAGACGAGACCCG
CAAACAGCTGAAGCTGCTGCGCAATCTCGGGGTGCGGGTGGCACTGGACGATTTCGGTTCCGGGTCCTGCTCGCTGGCGC
ATTTGCGCGATCTGGAACTGGATACCCTCAAACTCGATCGGCACCTGATCGCCCGATTGCCGGACTCGTCTCGCGACGCT
TCGCTGGTGCGCACGGTCATCGATTTATGCAAGGAATACGGCTTACTGGTGATTGCCGAAGGCGTGGAAACCGTCGAGCA
ATACCAGTGGCTGCAAGCTCATGGTTGCGAGTACGTGCAAGGGTTTCTGGTGGCGCGGCCGTTGGTCGCCGAGGACACCG
CACGCTTTACCGAGCCGTTCGACTGGAGCGCGTTGGCCGGTTGA

Upstream 100 bases:

>100_bases
CTAGAGTGAAGGCTCAGTGACTGTACGGTTTTCACGAGGAACCGCCCGGAACGCTGATCCGAGATGCCCCGACACGAGAT
GTCCCGACAAGAGAAGCAGC

Downstream 100 bases:

>100_bases
ATTCGCTACACTGGCGGCCTTTTCATGACCCGTGCCGCCCCATGACTGCGTTGAAATACCTCCAGGCCTATCCCGCGAAT
CTGCAGGATCAGGTGCGCCA

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 707; Mature: 707

Protein sequence:

>707_residues
MECAQPQPGEGSSVLLIVDDYPENLISMRALLQRQDWQVITAASGFEALSLLLEHDVDLVLLDVQMPGMDGFEVARLMRG
SQRTRLTPIIFLTANEQSQDAVIKGYASGAVDYLFKPFDPQILKPKVQALLEHQRNRRALQRLSQDLESARAFNASVLDN
AAEGILVLGEDGLIRFANPAISRLLNAPVKELEGQEFLDFLQKPHIPLWADSEFYASYKRGETLRLHDALLRTAPGQQVP
VALSCAPLPSEQHAMVVTVLDMSVVRHLHQQLEFQAVTDPLTGLLNRRGFYQTVENLLLRGERTDSSWVLMYLDLDGFKR
VNDSLGHDAGDRVLRWVSEQLKACLRPFDILARMGGDEFTALLDLEFPEQAAKIAEKLIERVSICQQIEGLDIALGASIG
IATYPDCGNNLDGLLRASDIAMYEAKRAGRQQYRFYDHEMNGRARSRLMLEESVRNAIENRDFNLVYQPQVAIGDGRIRG
FEALLRWQHPSVGDVPPGLFLPLLEEATLISRLGSWIYHRSAGQRKAWESEFSQDLVIGVSLSNTQFGLPNLVTELRQVL
ERHGLQPHQMEVEVTEEALTINPDETRKQLKLLRNLGVRVALDDFGSGSCSLAHLRDLELDTLKLDRHLIARLPDSSRDA
SLVRTVIDLCKEYGLLVIAEGVETVEQYQWLQAHGCEYVQGFLVARPLVAEDTARFTEPFDWSALAG

Sequences:

>Translated_707_residues
MECAQPQPGEGSSVLLIVDDYPENLISMRALLQRQDWQVITAASGFEALSLLLEHDVDLVLLDVQMPGMDGFEVARLMRG
SQRTRLTPIIFLTANEQSQDAVIKGYASGAVDYLFKPFDPQILKPKVQALLEHQRNRRALQRLSQDLESARAFNASVLDN
AAEGILVLGEDGLIRFANPAISRLLNAPVKELEGQEFLDFLQKPHIPLWADSEFYASYKRGETLRLHDALLRTAPGQQVP
VALSCAPLPSEQHAMVVTVLDMSVVRHLHQQLEFQAVTDPLTGLLNRRGFYQTVENLLLRGERTDSSWVLMYLDLDGFKR
VNDSLGHDAGDRVLRWVSEQLKACLRPFDILARMGGDEFTALLDLEFPEQAAKIAEKLIERVSICQQIEGLDIALGASIG
IATYPDCGNNLDGLLRASDIAMYEAKRAGRQQYRFYDHEMNGRARSRLMLEESVRNAIENRDFNLVYQPQVAIGDGRIRG
FEALLRWQHPSVGDVPPGLFLPLLEEATLISRLGSWIYHRSAGQRKAWESEFSQDLVIGVSLSNTQFGLPNLVTELRQVL
ERHGLQPHQMEVEVTEEALTINPDETRKQLKLLRNLGVRVALDDFGSGSCSLAHLRDLELDTLKLDRHLIARLPDSSRDA
SLVRTVIDLCKEYGLLVIAEGVETVEQYQWLQAHGCEYVQGFLVARPLVAEDTARFTEPFDWSALAG
>Mature_707_residues
MECAQPQPGEGSSVLLIVDDYPENLISMRALLQRQDWQVITAASGFEALSLLLEHDVDLVLLDVQMPGMDGFEVARLMRG
SQRTRLTPIIFLTANEQSQDAVIKGYASGAVDYLFKPFDPQILKPKVQALLEHQRNRRALQRLSQDLESARAFNASVLDN
AAEGILVLGEDGLIRFANPAISRLLNAPVKELEGQEFLDFLQKPHIPLWADSEFYASYKRGETLRLHDALLRTAPGQQVP
VALSCAPLPSEQHAMVVTVLDMSVVRHLHQQLEFQAVTDPLTGLLNRRGFYQTVENLLLRGERTDSSWVLMYLDLDGFKR
VNDSLGHDAGDRVLRWVSEQLKACLRPFDILARMGGDEFTALLDLEFPEQAAKIAEKLIERVSICQQIEGLDIALGASIG
IATYPDCGNNLDGLLRASDIAMYEAKRAGRQQYRFYDHEMNGRARSRLMLEESVRNAIENRDFNLVYQPQVAIGDGRIRG
FEALLRWQHPSVGDVPPGLFLPLLEEATLISRLGSWIYHRSAGQRKAWESEFSQDLVIGVSLSNTQFGLPNLVTELRQVL
ERHGLQPHQMEVEVTEEALTINPDETRKQLKLLRNLGVRVALDDFGSGSCSLAHLRDLELDTLKLDRHLIARLPDSSRDA
SLVRTVIDLCKEYGLLVIAEGVETVEQYQWLQAHGCEYVQGFLVARPLVAEDTARFTEPFDWSALAG

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=436, Percent_Identity=33.4862385321101, Blast_Score=244, Evalue=2e-65,
Organism=Escherichia coli, GI87081921, Length=442, Percent_Identity=31.9004524886878, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI226510982, Length=432, Percent_Identity=32.6388888888889, Blast_Score=191, Evalue=2e-49,
Organism=Escherichia coli, GI87081845, Length=246, Percent_Identity=32.1138211382114, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1788502, Length=243, Percent_Identity=29.6296296296296, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1788381, Length=542, Percent_Identity=27.4907749077491, Blast_Score=130, Evalue=4e-31,
Organism=Escherichia coli, GI87081743, Length=245, Percent_Identity=31.4285714285714, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1790496, Length=241, Percent_Identity=31.1203319502075, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI1787055, Length=259, Percent_Identity=27.027027027027, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1786507, Length=262, Percent_Identity=26.3358778625954, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI87081980, Length=251, Percent_Identity=28.2868525896414, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI87082096, Length=468, Percent_Identity=24.5726495726496, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1788849, Length=261, Percent_Identity=28.735632183908, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI87081881, Length=179, Percent_Identity=36.3128491620112, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI145693134, Length=181, Percent_Identity=33.1491712707182, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1786584, Length=163, Percent_Identity=29.4478527607362, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI87081977, Length=171, Percent_Identity=35.672514619883, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1787262, Length=157, Percent_Identity=33.7579617834395, Blast_Score=90, Evalue=6e-19,
Organism=Escherichia coli, GI87082007, Length=168, Percent_Identity=30.952380952381, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1788085, Length=172, Percent_Identity=33.1395348837209, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI1787802, Length=182, Percent_Identity=26.3736263736264, Blast_Score=80, Evalue=7e-16,
Organism=Escherichia coli, GI1787410, Length=137, Percent_Identity=32.1167883211679, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI87081974, Length=161, Percent_Identity=31.055900621118, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1789650, Length=422, Percent_Identity=23.2227488151659, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1787816, Length=171, Percent_Identity=31.5789473684211, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790863, Length=158, Percent_Identity=29.746835443038, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788550, Length=136, Percent_Identity=35.2941176470588, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1788956, Length=158, Percent_Identity=32.2784810126582, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1789809, Length=131, Percent_Identity=33.587786259542, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788713, Length=144, Percent_Identity=36.1111111111111, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI87082012, Length=97, Percent_Identity=41.2371134020619, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 79332; Mature: 79332

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MECAQPQPGEGSSVLLIVDDYPENLISMRALLQRQDWQVITAASGFEALSLLLEHDVDLV
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCEE
LLDVQMPGMDGFEVARLMRGSQRTRLTPIIFLTANEQSQDAVIKGYASGAVDYLFKPFDP
EEEEECCCCCHHHHHHHHHCCCCCEEEEEEEEEECCCCCCHHHHHHHCCHHHHHCCCCCC
QILKPKVQALLEHQRNRRALQRLSQDLESARAFNASVLDNAAEGILVLGEDGLIRFANPA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEECCCCCEEECCHH
ISRLLNAPVKELEGQEFLDFLQKPHIPLWADSEFYASYKRGETLRLHDALLRTAPGQQVP
HHHHHCCCHHHCCCHHHHHHHHCCCCCEECCCHHHHHHHCCCEEEHHHHHHHCCCCCCCC
VALSCAPLPSEQHAMVVTVLDMSVVRHLHQQLEFQAVTDPLTGLLNRRGFYQTVENLLLR
EEEEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHC
GERTDSSWVLMYLDLDGFKRVNDSLGHDAGDRVLRWVSEQLKACLRPFDILARMGGDEFT
CCCCCCCEEEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
ALLDLEFPEQAAKIAEKLIERVSICQQIEGLDIALGASIGIATYPDCGNNLDGLLRASDI
EEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEECCCCCCCHHHHHHHHHH
AMYEAKRAGRQQYRFYDHEMNGRARSRLMLEESVRNAIENRDFNLVYQPQVAIGDGRIRG
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCHHH
FEALLRWQHPSVGDVPPGLFLPLLEEATLISRLGSWIYHRSAGQRKAWESEFSQDLVIGV
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEE
SLSNTQFGLPNLVTELRQVLERHGLQPHQMEVEVTEEALTINPDETRKQLKLLRNLGVRV
EECCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCEEECCCHHHHHHHHHHHHCCCEE
ALDDFGSGSCSLAHLRDLELDTLKLDRHLIARLPDSSRDASLVRTVIDLCKEYGLLVIAE
EEECCCCCCEEHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEC
GVETVEQYQWLQAHGCEYVQGFLVARPLVAEDTARFTEPFDWSALAG
CHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHCHHHCCCCCCCCCCCC
>Mature Secondary Structure
MECAQPQPGEGSSVLLIVDDYPENLISMRALLQRQDWQVITAASGFEALSLLLEHDVDLV
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCEE
LLDVQMPGMDGFEVARLMRGSQRTRLTPIIFLTANEQSQDAVIKGYASGAVDYLFKPFDP
EEEEECCCCCHHHHHHHHHCCCCCEEEEEEEEEECCCCCCHHHHHHHCCHHHHHCCCCCC
QILKPKVQALLEHQRNRRALQRLSQDLESARAFNASVLDNAAEGILVLGEDGLIRFANPA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEECCCCCEEECCHH
ISRLLNAPVKELEGQEFLDFLQKPHIPLWADSEFYASYKRGETLRLHDALLRTAPGQQVP
HHHHHCCCHHHCCCHHHHHHHHCCCCCEECCCHHHHHHHCCCEEEHHHHHHHCCCCCCCC
VALSCAPLPSEQHAMVVTVLDMSVVRHLHQQLEFQAVTDPLTGLLNRRGFYQTVENLLLR
EEEEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHC
GERTDSSWVLMYLDLDGFKRVNDSLGHDAGDRVLRWVSEQLKACLRPFDILARMGGDEFT
CCCCCCCEEEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
ALLDLEFPEQAAKIAEKLIERVSICQQIEGLDIALGASIGIATYPDCGNNLDGLLRASDI
EEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEECCCCCCCHHHHHHHHHH
AMYEAKRAGRQQYRFYDHEMNGRARSRLMLEESVRNAIENRDFNLVYQPQVAIGDGRIRG
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCHHH
FEALLRWQHPSVGDVPPGLFLPLLEEATLISRLGSWIYHRSAGQRKAWESEFSQDLVIGV
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEE
SLSNTQFGLPNLVTELRQVLERHGLQPHQMEVEVTEEALTINPDETRKQLKLLRNLGVRV
EECCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCEEECCCHHHHHHHHHHHHCCCEE
ALDDFGSGSCSLAHLRDLELDTLKLDRHLIARLPDSSRDASLVRTVIDLCKEYGLLVIAE
EEECCCCCCEEHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEC
GVETVEQYQWLQAHGCEYVQGFLVARPLVAEDTARFTEPFDWSALAG
CHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHCHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]