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The map label for this gene is hcr [H]

Identifier: 77461436

GI number: 77461436

Start: 5863671

End: 5864771

Strand: Reverse

Name: hcr [H]

Synonym: Pfl01_5215

Alternate gene names: 77461436

Gene position: 5864771-5863671 (Counterclockwise)

Preceding gene: 77461438

Following gene: 77461430

Centisome position: 91.09

GC content: 61.94

Gene sequence:

>1101_bases
ATGTCGAACAGCTTCCTGAATCCGGTCACCACCCAGACCTGGGCCAATGGCCGACACATCGTCCGTTGCGTCAAAGTCAT
CCAGGAAACCTGGGATGTGCGCACCTTCTGCTTCATGGCCGACCAGCCGATCCTGTTCTTCTTCAAGCCCGGGCAGTTCG
TGACCCTGGAGCTGGAGATCGAAGGCCAGCCGATCATGCGTTCGTACACCATCTCCAGCTCGCCGTCGGTGCCGTACAGT
TTTTCGGTGACCATCAAGCGCGTGCCGGGGGGCAAGGTCTCCAACTGGTTGCACGACACCCTGCATGAAGGCCAGGAGCT
GGCGGTGCACGGACCGGTCGGGCTGTTCAACGCCATCGATTTCCCGAGCCCGAAAGTGCTCTACCTGAGCGGTGGCGTCG
GAATCACCCCAGTGATGTCCATGGCGCGCTGGTTCTACGACACCAACGGCAACGTCGACATGACGTTCATCCACAGTGCC
CGCTCGCCGAAAGACATCATTTACCACCGCGAGCTGGAACACATGGCGTCGCGGATCGACAACTTCAGCCTGCACCTGAT
CTGCGAAAAGCATGGGCTGGGCGAGCCGTGGGCCGGCTATCGCGGCTACCTCAACCACAAGATGCTCGAACTGATGGTGC
CGGACTTCCTCGAGCGCGAAGTCTTCTGCTGCGGCCCGACGCCGTACATGACGGCGGTCAAACGCCTGCTGGAAAACGCC
GGCTACGACATGAAGCGCTATCACGAGGAATCCTTCGGCGCCACGCCGCCGGAAGCCCGTGCCGATGCGGTGGAGCAGGC
CGAACAGGCAGCGGAAGCACCGGAAGTGCCGGCGGCGGATCTGCACCTGGTGGAATTCACCTCTTCGGACAAGAGCATCC
GTGTCGCGCCGGGCGAGACCGTGCATGCGGCGGCTGCCAAGGTCGGCCTGATGATCCCGAAAGCCTGCGGCATGGGGATC
TGCGGGACGTGCAAGGTGCTCAAGCTGGGCGGCGAGGTGGAGATGGATCACAACGGCGGGATCACCGAGGACGACGAGGC
GGAGGGGTACATTCTTTCTTGCTGCAGTGTGCCGAAGGGGGATGTTCGGATCGAATATTGA

Upstream 100 bases:

>100_bases
GTCGCGATAAGTATGTCAATGTCGCGGATAGGTAAACGGGGCGTTCGCGCTATACGCAGAATCGCCACATGAAGGCCGAC
AGTCGGCCGTGGAGAACAGC

Downstream 100 bases:

>100_bases
ATTCAGTTTGCAGGCTTGGGGGCGATCTCTCGTAGGGGAGATCGTATGAAGTAATTAGTTGCTGTTTTTAAATAACTTCT
AATGCGGCGAGAAGTCCAAA

Product: oxidoreductase FAD-binding region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSNSFLNPVTTQTWANGRHIVRCVKVIQETWDVRTFCFMADQPILFFFKPGQFVTLELEIEGQPIMRSYTISSSPSVPYS
FSVTIKRVPGGKVSNWLHDTLHEGQELAVHGPVGLFNAIDFPSPKVLYLSGGVGITPVMSMARWFYDTNGNVDMTFIHSA
RSPKDIIYHRELEHMASRIDNFSLHLICEKHGLGEPWAGYRGYLNHKMLELMVPDFLEREVFCCGPTPYMTAVKRLLENA
GYDMKRYHEESFGATPPEARADAVEQAEQAAEAPEVPAADLHLVEFTSSDKSIRVAPGETVHAAAAKVGLMIPKACGMGI
CGTCKVLKLGGEVEMDHNGGITEDDEAEGYILSCCSVPKGDVRIEY

Sequences:

>Translated_366_residues
MSNSFLNPVTTQTWANGRHIVRCVKVIQETWDVRTFCFMADQPILFFFKPGQFVTLELEIEGQPIMRSYTISSSPSVPYS
FSVTIKRVPGGKVSNWLHDTLHEGQELAVHGPVGLFNAIDFPSPKVLYLSGGVGITPVMSMARWFYDTNGNVDMTFIHSA
RSPKDIIYHRELEHMASRIDNFSLHLICEKHGLGEPWAGYRGYLNHKMLELMVPDFLEREVFCCGPTPYMTAVKRLLENA
GYDMKRYHEESFGATPPEARADAVEQAEQAAEAPEVPAADLHLVEFTSSDKSIRVAPGETVHAAAAKVGLMIPKACGMGI
CGTCKVLKLGGEVEMDHNGGITEDDEAEGYILSCCSVPKGDVRIEY
>Mature_365_residues
SNSFLNPVTTQTWANGRHIVRCVKVIQETWDVRTFCFMADQPILFFFKPGQFVTLELEIEGQPIMRSYTISSSPSVPYSF
SVTIKRVPGGKVSNWLHDTLHEGQELAVHGPVGLFNAIDFPSPKVLYLSGGVGITPVMSMARWFYDTNGNVDMTFIHSAR
SPKDIIYHRELEHMASRIDNFSLHLICEKHGLGEPWAGYRGYLNHKMLELMVPDFLEREVFCCGPTPYMTAVKRLLENAG
YDMKRYHEESFGATPPEARADAVEQAEQAAEAPEVPAADLHLVEFTSSDKSIRVAPGETVHAAAAKVGLMIPKACGMGIC
GTCKVLKLGGEVEMDHNGGITEDDEAEGYILSCCSVPKGDVRIEY

Specific function: NADH oxidoreductase acting in concert with HCP [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1787098, Length=338, Percent_Identity=28.698224852071, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1787658, Length=359, Percent_Identity=27.0194986072423, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1788903, Length=212, Percent_Identity=25.4716981132075, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788104, Length=339, Percent_Identity=25.9587020648968, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323510, Length=178, Percent_Identity=25.2808988764045, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323552, Length=194, Percent_Identity=24.2268041237113, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 40597; Mature: 40466

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSFLNPVTTQTWANGRHIVRCVKVIQETWDVRTFCFMADQPILFFFKPGQFVTLELEI
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCEEEEECCCCEEEEEEEE
EGQPIMRSYTISSSPSVPYSFSVTIKRVPGGKVSNWLHDTLHEGQELAVHGPVGLFNAID
CCCCEEEEEEECCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCHHHCCC
FPSPKVLYLSGGVGITPVMSMARWFYDTNGNVDMTFIHSARSPKDIIYHRELEHMASRID
CCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCC
NFSLHLICEKHGLGEPWAGYRGYLNHKMLELMVPDFLEREVFCCGPTPYMTAVKRLLENA
CCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHC
GYDMKRYHEESFGATPPEARADAVEQAEQAAEAPEVPAADLHLVEFTSSDKSIRVAPGET
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEECCCCC
VHAAAAKVGLMIPKACGMGICGTCKVLKLGGEVEMDHNGGITEDDEAEGYILSCCSVPKG
HHHHHHHHHEEEHHHCCCCCCCCEEEEEECCEEEECCCCCCCCCCCCCCEEEEECCCCCC
DVRIEY
CEEEEC
>Mature Secondary Structure 
SNSFLNPVTTQTWANGRHIVRCVKVIQETWDVRTFCFMADQPILFFFKPGQFVTLELEI
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCEEEEECCCCEEEEEEEE
EGQPIMRSYTISSSPSVPYSFSVTIKRVPGGKVSNWLHDTLHEGQELAVHGPVGLFNAID
CCCCEEEEEEECCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCHHHCCC
FPSPKVLYLSGGVGITPVMSMARWFYDTNGNVDMTFIHSARSPKDIIYHRELEHMASRID
CCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCC
NFSLHLICEKHGLGEPWAGYRGYLNHKMLELMVPDFLEREVFCCGPTPYMTAVKRLLENA
CCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHC
GYDMKRYHEESFGATPPEARADAVEQAEQAAEAPEVPAADLHLVEFTSSDKSIRVAPGET
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEECCCCC
VHAAAAKVGLMIPKACGMGICGTCKVLKLGGEVEMDHNGGITEDDEAEGYILSCCSVPKG
HHHHHHHHHEEEHHHCCCCCCCCEEEEEECCEEEECCCCCCCCCCCCCCEEEEECCCCCC
DVRIEY
CEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10651802 [H]