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The map label for this gene is creB [H]

Identifier: 77461417

GI number: 77461417

Start: 5845138

End: 5845818

Strand: Reverse

Name: creB [H]

Synonym: Pfl01_5196

Alternate gene names: 77461417

Gene position: 5845818-5845138 (Counterclockwise)

Preceding gene: 77461418

Following gene: 77461416

Centisome position: 90.8

GC content: 62.41

Gene sequence:

>681_bases
ATGCCTCATATCCTGATTGTCGAAGACGAAGCGGCGATTGCCGACACGCTGATTTTTGCCTTGCAGGGCGAGGGCTTCAC
CACGACCTGGCTGAGCCTGGGCGCGGCGGCGCTGGAGCATCAGCGTCAGACTCCGGCCGATCTGATCATCCTCGACATCG
GCCTGCCGGACATCAGCGGCTTCGAGACCTGTAAACAGCTTCGTCGCTTCAGTGAAGTACCGGTGCTGTTCCTCAGCGCG
CGCAATGCCGAAATCGACCGGGTGGTGGGCCTGGAAATCGGAGCCGACGATTACGTCGTCAAACCGTTTTCACCGCGAGA
GGTGGCGGCCCGGGTCCGGGCGATTCTCAAGCGCATGGCGCCACGCCCGGTCATCGAAGCATCCTCGGCGCTGTTTCGCA
TCGATCCCGAACGCGTGCAGATCAGCTATCGCGGCCAGCCCCTGAGCCTGACCCGCCATGAATTCCGATTGTTGCAATGC
CTGCTCGAGCAACCCGAGCGGGTATTCAGCCGCGAGCAATTGCTCGATGCGTTGGGCGTGGCGGCGGATGCCGGATACGA
GCGCAGCATCGACAGCCATATCAAAAGCGTGCGCGCCAAATTGCGTCTCGTACGCGCCGAGGCCGAGCCGATCCAGACCC
ATCGCGGCCTCGGCTACAGCTACAGTCCGGGGAATAGCTGA

Upstream 100 bases:

>100_bases
TTCACGGCGGACAAGCCGGACTGCTAAACCAAGTGGTCTCATTGACGTAACGCCGGGCTTGGGGCACCGTTCGCGCACTT
AACCCACAGGCTCGGACGCC

Downstream 100 bases:

>100_bases
TGACGCTGGGGCTGCGAATTTTCCTGGTGTACGTGCTGTTCATCGGCCTGACCGGGTATTTCGTGCTCAACACGGTGATG
GAAGAAATCCGCCCGGGCGT

Product: DNA-binding response regulator CreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MPHILIVEDEAAIADTLIFALQGEGFTTTWLSLGAAALEHQRQTPADLIILDIGLPDISGFETCKQLRRFSEVPVLFLSA
RNAEIDRVVGLEIGADDYVVKPFSPREVAARVRAILKRMAPRPVIEASSALFRIDPERVQISYRGQPLSLTRHEFRLLQC
LLEQPERVFSREQLLDALGVAADAGYERSIDSHIKSVRAKLRLVRAEAEPIQTHRGLGYSYSPGNS

Sequences:

>Translated_226_residues
MPHILIVEDEAAIADTLIFALQGEGFTTTWLSLGAAALEHQRQTPADLIILDIGLPDISGFETCKQLRRFSEVPVLFLSA
RNAEIDRVVGLEIGADDYVVKPFSPREVAARVRAILKRMAPRPVIEASSALFRIDPERVQISYRGQPLSLTRHEFRLLQC
LLEQPERVFSREQLLDALGVAADAGYERSIDSHIKSVRAKLRLVRAEAEPIQTHRGLGYSYSPGNS
>Mature_225_residues
PHILIVEDEAAIADTLIFALQGEGFTTTWLSLGAAALEHQRQTPADLIILDIGLPDISGFETCKQLRRFSEVPVLFLSAR
NAEIDRVVGLEIGADDYVVKPFSPREVAARVRAILKRMAPRPVIEASSALFRIDPERVQISYRGQPLSLTRHEFRLLQCL
LEQPERVFSREQLLDALGVAADAGYERSIDSHIKSVRAKLRLVRAEAEPIQTHRGLGYSYSPGNS

Specific function: Member of the two-component regulatory system CreC/CreB involved in catabolic regulation [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=51.8018018018018, Blast_Score=227, Evalue=6e-61,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=47.5336322869955, Blast_Score=194, Evalue=6e-51,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=39.0134529147982, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=32.3144104803493, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=33.4862385321101, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=36.5217391304348, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=37.5545851528384, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=35.0877192982456, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=33.1896551724138, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790552, Length=217, Percent_Identity=33.1797235023041, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=35.2941176470588, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=33.7777777777778, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=30.1369863013699, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=28.3898305084746, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25169; Mature: 25038

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHILIVEDEAAIADTLIFALQGEGFTTTWLSLGAAALEHQRQTPADLIILDIGLPDISG
CCCEEEEECCHHHHHHHHEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCH
FETCKQLRRFSEVPVLFLSARNAEIDRVVGLEIGADDYVVKPFSPREVAARVRAILKRMA
HHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEECCCCEEECCCCHHHHHHHHHHHHHHHC
PRPVIEASSALFRIDPERVQISYRGQPLSLTRHEFRLLQCLLEQPERVFSREQLLDALGV
CCCCHHCCCCEEEECHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AADAGYERSIDSHIKSVRAKLRLVRAEAEPIQTHRGLGYSYSPGNS
HHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
PHILIVEDEAAIADTLIFALQGEGFTTTWLSLGAAALEHQRQTPADLIILDIGLPDISG
CCEEEEECCHHHHHHHHEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCH
FETCKQLRRFSEVPVLFLSARNAEIDRVVGLEIGADDYVVKPFSPREVAARVRAILKRMA
HHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEECCCCEEECCCCHHHHHHHHHHHHHHHC
PRPVIEASSALFRIDPERVQISYRGQPLSLTRHEFRLLQCLLEQPERVFSREQLLDALGV
CCCCHHCCCCEEEECHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AADAGYERSIDSHIKSVRAKLRLVRAEAEPIQTHRGLGYSYSPGNS
HHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3531171; 7610040; 9278503 [H]