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The map label for this gene is lrp [C]

Identifier: 77461374

GI number: 77461374

Start: 5793893

End: 5794354

Strand: Direct

Name: lrp [C]

Synonym: Pfl01_5153

Alternate gene names: 77461374

Gene position: 5793893-5794354 (Clockwise)

Preceding gene: 77461373

Following gene: 77461375

Centisome position: 89.99

GC content: 59.74

Gene sequence:

>462_bases
ATGTCCAAAATCGCCTCCACAGGTCTTGATGAAATCGACCGCCAGCTGATCGCAGCCCTGCAAATCAACGCCCGCGAAAG
CGTGGCGATGCTGGCCCGGCAATTGGGGATCGCCCGCACGACCGTGACTTCACGACTGGCGCGGCTGGAAAAGGCCAAAG
TCATCACCGGCTACAGCGTGCGTCTGGGCCAGCGCGTGGTGGACGGCGGATTGCAGGCTTACGTCGGGATCAAGGTGCAG
CCACGCTCCGGCAAAGAGGTGTTGCGCCGTTTGAGCGCAATGGCTCAGGTGCAGCAATTGTGCGCGGTGAGTGGCGAATT
CGATTATGTGGCGTGGCTGCGGACCGATTCGCCGGAGCAGCTTGATCAACTTCTGGATCAGATCGGCAGCGTAGACGGTG
TGGAGAAAACCACGACCTCGATCATTCTCAGCAGCAAGATTGATCGCGGCCATCCAGTCTGA

Upstream 100 bases:

>100_bases
GTCGCGCGCCCTCTCCAATAGACAGGAGGTTTGATAGATGCGCTAATTGACTGATTCGCATACGTCGAAGCACGTAGGCA
GGCCAATTCCGAGATAACCC

Downstream 100 bases:

>100_bases
CCAATAAAATCGTCAGATTGCAGCATATGCACTCAAAACGACGACACATTGCGTCTTATTAACGTGTTCTACGCTCCCTA
GAATGGCTGGCATCTTTTCC

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 152

Protein sequence:

>153_residues
MSKIASTGLDEIDRQLIAALQINARESVAMLARQLGIARTTVTSRLARLEKAKVITGYSVRLGQRVVDGGLQAYVGIKVQ
PRSGKEVLRRLSAMAQVQQLCAVSGEFDYVAWLRTDSPEQLDQLLDQIGSVDGVEKTTTSIILSSKIDRGHPV

Sequences:

>Translated_153_residues
MSKIASTGLDEIDRQLIAALQINARESVAMLARQLGIARTTVTSRLARLEKAKVITGYSVRLGQRVVDGGLQAYVGIKVQ
PRSGKEVLRRLSAMAQVQQLCAVSGEFDYVAWLRTDSPEQLDQLLDQIGSVDGVEKTTTSIILSSKIDRGHPV
>Mature_152_residues
SKIASTGLDEIDRQLIAALQINARESVAMLARQLGIARTTVTSRLARLEKAKVITGYSVRLGQRVVDGGLQAYVGIKVQP
RSGKEVLRRLSAMAQVQQLCAVSGEFDYVAWLRTDSPEQLDQLLDQIGSVDGVEKTTTSIILSSKIDRGHPV

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=142, Percent_Identity=28.169014084507, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1790182, Length=143, Percent_Identity=25.1748251748252, Blast_Score=60, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 16662; Mature: 16531

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIASTGLDEIDRQLIAALQINARESVAMLARQLGIARTTVTSRLARLEKAKVITGYSV
CCCCHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RLGQRVVDGGLQAYVGIKVQPRSGKEVLRRLSAMAQVQQLCAVSGEFDYVAWLRTDSPEQ
HHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHH
LDQLLDQIGSVDGVEKTTTSIILSSKIDRGHPV
HHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SKIASTGLDEIDRQLIAALQINARESVAMLARQLGIARTTVTSRLARLEKAKVITGYSV
CCCHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RLGQRVVDGGLQAYVGIKVQPRSGKEVLRRLSAMAQVQQLCAVSGEFDYVAWLRTDSPEQ
HHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHH
LDQLLDQIGSVDGVEKTTTSIILSSKIDRGHPV
HHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]