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The map label for this gene is uvrY [H]

Identifier: 77461347

GI number: 77461347

Start: 5759348

End: 5759977

Strand: Reverse

Name: uvrY [H]

Synonym: Pfl01_5126

Alternate gene names: 77461347

Gene position: 5759977-5759348 (Counterclockwise)

Preceding gene: 77461348

Following gene: 77461346

Centisome position: 89.46

GC content: 62.7

Gene sequence:

>630_bases
GTGATCCGTGTACTGGTAGCCGAAGACCACACCATCGTTCGCGAAGGCATCAAGCAATTGATCGGCCTGGCCAAGGATCT
GCAAGTGGTGGGGGAGGCGAGCAATGGCGAGCAGTTGCTGGAAACCCTGCGCAACGTGCCCTGCGAAGTGGTGCTGCTGG
ATATCTCGATGCCCGGCGTCAACGGGCTCGAAGCGATTCCGCGGATCCGCGCGCTGAACCATCCGCCGGCGATTCTGGTG
CTGTCGATGCACGACGAAGCGCAGATGGCCGCCCGGGCACTGAAGATCGGCGCCGCCGGGTATGCGACCAAGGACAGTGA
TCCGGCGCTGCTGCTGACGGCAATTCGCAAGGTCGCTGCAGGTGGGCGTTACATCGACCCGGAGCTGGCCGACCGCATGG
TCTTCGAAGTCGGCCTGACCGATGCGCGGCCGCTGCACTCGTTGCTGTCGGAGCGCGAGTTCTCGGTGTTCGAACGGCTG
GCGCAAGGCGCCAACGTCAACGACATCGCCCAGCAATTGGCCCTGAGCAGCAAGACCATCAGCACCCACAAGGCGCGGCT
GATGCAGAAACTCAACATCACTTCGCTCGCCGAGCTGGTGAAGTACGCGATGGAACACAAGCTGCTCTGA

Upstream 100 bases:

>100_bases
CGAGCGGGTGTTGATCATGGGCGGGCAGCTGTCACTCGACAGCGAACCGGGCGAGGGCACCACGCTGAGCGTGCGGGTGC
CACTGGATGAGGAGAAGTAA

Downstream 100 bases:

>100_bases
GCGACATATCCATTAGCGACAGGCGCTTTTGCCGGTTCTGGCGGCTTGAGCCCCGACCCATGCGCCGGGTTTGCCAAAAC
GCGCCATCCGTGTAGGGCAA

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MIRVLVAEDHTIVREGIKQLIGLAKDLQVVGEASNGEQLLETLRNVPCEVVLLDISMPGVNGLEAIPRIRALNHPPAILV
LSMHDEAQMAARALKIGAAGYATKDSDPALLLTAIRKVAAGGRYIDPELADRMVFEVGLTDARPLHSLLSEREFSVFERL
AQGANVNDIAQQLALSSKTISTHKARLMQKLNITSLAELVKYAMEHKLL

Sequences:

>Translated_209_residues
MIRVLVAEDHTIVREGIKQLIGLAKDLQVVGEASNGEQLLETLRNVPCEVVLLDISMPGVNGLEAIPRIRALNHPPAILV
LSMHDEAQMAARALKIGAAGYATKDSDPALLLTAIRKVAAGGRYIDPELADRMVFEVGLTDARPLHSLLSEREFSVFERL
AQGANVNDIAQQLALSSKTISTHKARLMQKLNITSLAELVKYAMEHKLL
>Mature_209_residues
MIRVLVAEDHTIVREGIKQLIGLAKDLQVVGEASNGEQLLETLRNVPCEVVLLDISMPGVNGLEAIPRIRALNHPPAILV
LSMHDEAQMAARALKIGAAGYATKDSDPALLLTAIRKVAAGGRYIDPELADRMVFEVGLTDARPLHSLLSEREFSVFERL
AQGANVNDIAQQLALSSKTISTHKARLMQKLNITSLAELVKYAMEHKLL

Specific function: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. UvrY activates the transcription of the untranslated csrB RNA and of barA, in an autoregulatory loop. Mediates the

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=211, Percent_Identity=39.8104265402844, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1790102, Length=201, Percent_Identity=39.8009950248756, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1786747, Length=206, Percent_Identity=28.6407766990291, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1788521, Length=198, Percent_Identity=33.3333333333333, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1788712, Length=204, Percent_Identity=27.9411764705882, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1787473, Length=184, Percent_Identity=36.9565217391304, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788546, Length=207, Percent_Identity=29.951690821256, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22772; Mature: 22772

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVLVAEDHTIVREGIKQLIGLAKDLQVVGEASNGEQLLETLRNVPCEVVLLDISMPGV
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEEECCCCC
NGLEAIPRIRALNHPPAILVLSMHDEAQMAARALKIGAAGYATKDSDPALLLTAIRKVAA
CHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHC
GGRYIDPELADRMVFEVGLTDARPLHSLLSEREFSVFERLAQGANVNDIAQQLALSSKTI
CCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
STHKARLMQKLNITSLAELVKYAMEHKLL
HHHHHHHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIRVLVAEDHTIVREGIKQLIGLAKDLQVVGEASNGEQLLETLRNVPCEVVLLDISMPGV
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEEECCCCC
NGLEAIPRIRALNHPPAILVLSMHDEAQMAARALKIGAAGYATKDSDPALLLTAIRKVAA
CHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHC
GGRYIDPELADRMVFEVGLTDARPLHSLLSEREFSVFERLAQGANVNDIAQQLALSSKTI
CCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
STHKARLMQKLNITSLAELVKYAMEHKLL
HHHHHHHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]