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The map label for this gene is speD

Identifier: 77461330

GI number: 77461330

Start: 5742343

End: 5743137

Strand: Reverse

Name: speD

Synonym: Pfl01_5109

Alternate gene names: 77461330

Gene position: 5743137-5742343 (Counterclockwise)

Preceding gene: 77461331

Following gene: 77461323

Centisome position: 89.2

GC content: 54.09

Gene sequence:

>795_bases
GTGAAAAGCAAACTCAAGCTCCACGGGTTCAATAACCTGACAAAGACCTTGAGCTTCAACATCTATGACATCTGCTACGC
GGAAACCCCGCAAGACCAGCAGGCTTACGTCGAGTACATCAATCAAGAGTACAACGCCGAACGCCTGACGCAGATCCTCA
CGGAAGTTGTCGAAATCATTGGTGCCAACATTCTGAACATTGCGAGTCAGAACTATGAGCCTCAGGGTGCCAGCGTCACG
ATTCTGATCTCGGAAGAGCCGGTGACCCCGACCGAAAGCCAGATCGAAGAGTCCCCGGGCCCGTTGCCCGAAATCATCCT
GGCCCACCTCGACAAGAGCCACATCACGGTGCACACCTACCCGGAAATCCATCCGGACGCCGGTATTGCGACTTTCCGTG
TGGACATCGACGTGTCGACCTGTGGTGTCATTTCACCGCTCAAAGCGCTCAACTTCCTCATTCACCAGTTCGATTCGGAC
ATCGTGACCGTGGATTACCGTGTGCGCGGCTTCACCCGTGACGTTGAAGGCAACAAGCACTTCATCGACCACGAGATCAA
CTCGATCCAGAACTACCTCTCCGAAGACACCCGCGACGCGTACCAGATGACCGACGTGAACGTGTACCAGGAAAACCTGT
TCCACACCAAAATGCTGTTGAAGAACTTCGAACTGGACAACTACCTGTTCGGCGATGCCACCAGCAACCTGTCGTCCGAG
CAACGTGCTCAGGTGACCGAGCGTGTGAAACACGAAATGCTGGAAATCTTCTACGCGCGCAATATGCCGAGCTAA

Upstream 100 bases:

>100_bases
TCGCGAAGAGGTGTTAACCGTCCTACGCAGGTGCGTTGTTCGCACTTGACGGGCATGCTTGATCACGCGGCCGTGCCGCA
TACATAGAGAGTTTTTAACG

Downstream 100 bases:

>100_bases
GAAGTCCGGGCACAAAAAAAAGGCGACTGCTTTGCGGCAGTTGCCTTTTTTGTGGGCGTTTTTCAGATCCGGTAAGTGCT
CTTGGTCATCACCTTGGCCA

Product: S-adenosylmethionine decarboxylase

Products: NA

Alternate protein names: AdoMetDC; SAMDC

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MKSKLKLHGFNNLTKTLSFNIYDICYAETPQDQQAYVEYINQEYNAERLTQILTEVVEIIGANILNIASQNYEPQGASVT
ILISEEPVTPTESQIEESPGPLPEIILAHLDKSHITVHTYPEIHPDAGIATFRVDIDVSTCGVISPLKALNFLIHQFDSD
IVTVDYRVRGFTRDVEGNKHFIDHEINSIQNYLSEDTRDAYQMTDVNVYQENLFHTKMLLKNFELDNYLFGDATSNLSSE
QRAQVTERVKHEMLEIFYARNMPS

Sequences:

>Translated_264_residues
MKSKLKLHGFNNLTKTLSFNIYDICYAETPQDQQAYVEYINQEYNAERLTQILTEVVEIIGANILNIASQNYEPQGASVT
ILISEEPVTPTESQIEESPGPLPEIILAHLDKSHITVHTYPEIHPDAGIATFRVDIDVSTCGVISPLKALNFLIHQFDSD
IVTVDYRVRGFTRDVEGNKHFIDHEINSIQNYLSEDTRDAYQMTDVNVYQENLFHTKMLLKNFELDNYLFGDATSNLSSE
QRAQVTERVKHEMLEIFYARNMPS
>Mature_264_residues
MKSKLKLHGFNNLTKTLSFNIYDICYAETPQDQQAYVEYINQEYNAERLTQILTEVVEIIGANILNIASQNYEPQGASVT
ILISEEPVTPTESQIEESPGPLPEIILAHLDKSHITVHTYPEIHPDAGIATFRVDIDVSTCGVISPLKALNFLIHQFDSD
IVTVDYRVRGFTRDVEGNKHFIDHEINSIQNYLSEDTRDAYQMTDVNVYQENLFHTKMLLKNFELDNYLFGDATSNLSSE
QRAQVTERVKHEMLEIFYARNMPS

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily

Homologues:

Organism=Escherichia coli, GI1786311, Length=262, Percent_Identity=66.793893129771, Blast_Score=382, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPED_PSEPF (Q3K5V8)

Other databases:

- EMBL:   CP000094
- RefSeq:   YP_350837.1
- ProteinModelPortal:   Q3K5V8
- STRING:   Q3K5V8
- GeneID:   3716449
- GenomeReviews:   CP000094_GR
- KEGG:   pfo:Pfl01_5109
- eggNOG:   COG1586
- HOGENOM:   HBG303125
- OMA:   YNAERLT
- ProtClustDB:   PRK05462
- BioCyc:   PFLU205922:PFL_5109-MONOMER
- HAMAP:   MF_00465
- InterPro:   IPR003826
- InterPro:   IPR009165
- InterPro:   IPR016067
- Gene3D:   G3DSA:3.60.90.10
- PIRSF:   PIRSF001356
- TIGRFAMs:   TIGR03331

Pfam domain/function: PF02675 AdoMet_dc; SSF56276 S-AdenosylMet_decarbase_core

EC number: =4.1.1.50

Molecular weight: Translated: 30207; Mature: 30207

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: ACT_SITE 113-113 ACT_SITE 118-118 ACT_SITE 141-141

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKLKLHGFNNLTKTLSFNIYDICYAETPQDQQAYVEYINQEYNAERLTQILTEVVEII
CCCCEEECCCCCHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
GANILNIASQNYEPQGASVTILISEEPVTPTESQIEESPGPLPEIILAHLDKSHITVHTY
CCHHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHCCCCCHHHHHHHHCCCCCEEEEEC
PEIHPDAGIATFRVDIDVSTCGVISPLKALNFLIHQFDSDIVTVDYRVRGFTRDVEGNKH
CCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECEEECCCCCCE
FIDHEINSIQNYLSEDTRDAYQMTDVNVYQENLFHTKMLLKNFELDNYLFGDATSNLSSE
EHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHH
QRAQVTERVKHEMLEIFYARNMPS
HHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKSKLKLHGFNNLTKTLSFNIYDICYAETPQDQQAYVEYINQEYNAERLTQILTEVVEII
CCCCEEECCCCCHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
GANILNIASQNYEPQGASVTILISEEPVTPTESQIEESPGPLPEIILAHLDKSHITVHTY
CCHHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHCCCCCHHHHHHHHCCCCCEEEEEC
PEIHPDAGIATFRVDIDVSTCGVISPLKALNFLIHQFDSDIVTVDYRVRGFTRDVEGNKH
CCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECEEECCCCCCE
FIDHEINSIQNYLSEDTRDAYQMTDVNVYQENLFHTKMLLKNFELDNYLFGDATSNLSSE
EHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHH
QRAQVTERVKHEMLEIFYARNMPS
HHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA