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The map label for this gene is erpA [H]

Identifier: 77461322

GI number: 77461322

Start: 5736115

End: 5736465

Strand: Reverse

Name: erpA [H]

Synonym: Pfl01_5101

Alternate gene names: 77461322

Gene position: 5736465-5736115 (Counterclockwise)

Preceding gene: 77461323

Following gene: 77461319

Centisome position: 89.1

GC content: 56.7

Gene sequence:

>351_bases
ATGAGCGTCGAATCCTTCACCCCCACGGCTTTGCAATTCACTCAAGGTGCCGCGCACAAGGTGAAGAGCCTGGTCGATGA
AGAGGGGAATGATCGCTTGAAGCTGCGCGTATTCGTTACGGGCGGCGGTTGTTCAGGGTTTCAGTACGGCTTCACCTTCG
ATGAAGATGTGGCCGAGGACGACACCATCGTCGAGCGCGAAGGCGTCAGTCTGGTGGTCGATCCGATGAGCTTCCAGTAC
CTGGCAGGTGCCGAGGTGGATTATCAGGAAGGTCTGGAAGGTTCGCGTTTCGTGATCAAGAACCCGAATGCCACCACCAC
TTGTGGTTGCGGCTCCTCGTTCTCGATCTGA

Upstream 100 bases:

>100_bases
TTATTGATATACCGTAACAATAGTTGACCGATTTTCTAGGACAAGCGGATAATGCGCGTCATCACGCATTATGGCGGCGT
AACGCCGGGAGATAGTCAGC

Downstream 100 bases:

>100_bases
TCGCGCTTCACCGTACACAACAAAACGCCGCAGAACCTCACGGTTCTGCGGCGTTTTGTTATCTGCGATTTGTCAGTTGG
GGTAGATGGCGCCGAGTACG

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 116; Mature: 115

Protein sequence:

>116_residues
MSVESFTPTALQFTQGAAHKVKSLVDEEGNDRLKLRVFVTGGGCSGFQYGFTFDEDVAEDDTIVEREGVSLVVDPMSFQY
LAGAEVDYQEGLEGSRFVIKNPNATTTCGCGSSFSI

Sequences:

>Translated_116_residues
MSVESFTPTALQFTQGAAHKVKSLVDEEGNDRLKLRVFVTGGGCSGFQYGFTFDEDVAEDDTIVEREGVSLVVDPMSFQY
LAGAEVDYQEGLEGSRFVIKNPNATTTCGCGSSFSI
>Mature_115_residues
SVESFTPTALQFTQGAAHKVKSLVDEEGNDRLKLRVFVTGGGCSGFQYGFTFDEDVAEDDTIVEREGVSLVVDPMSFQYL
AGAEVDYQEGLEGSRFVIKNPNATTTCGCGSSFSI

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=83, Percent_Identity=49.3975903614458, Blast_Score=81, Evalue=2e-16,
Organism=Homo sapiens, GI52426768, Length=118, Percent_Identity=33.8983050847458, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1786351, Length=106, Percent_Identity=69.811320754717, Blast_Score=162, Evalue=6e-42,
Organism=Escherichia coli, GI1788877, Length=109, Percent_Identity=36.697247706422, Blast_Score=67, Evalue=4e-13,
Organism=Escherichia coli, GI1787974, Length=114, Percent_Identity=32.4561403508772, Blast_Score=59, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71998452, Length=113, Percent_Identity=38.9380530973451, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25146411, Length=110, Percent_Identity=36.3636363636364, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193209025, Length=107, Percent_Identity=36.4485981308411, Blast_Score=76, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323001, Length=82, Percent_Identity=37.8048780487805, Blast_Score=70, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24649697, Length=83, Percent_Identity=48.1927710843374, Blast_Score=76, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24642263, Length=110, Percent_Identity=35.4545454545455, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 12506; Mature: 12375

Theoretical pI: Translated: 4.04; Mature: 4.04

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVESFTPTALQFTQGAAHKVKSLVDEEGNDRLKLRVFVTGGGCSGFQYGFTFDEDVAED
CCCCCCCCCEEEECCCHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCC
DTIVEREGVSLVVDPMSFQYLAGAEVDYQEGLEGSRFVIKNPNATTTCGCGSSFSI
CCEEECCCCEEEECCCCEEEECCCCCCHHHCCCCCEEEEECCCCCEEECCCCCCCC
>Mature Secondary Structure 
SVESFTPTALQFTQGAAHKVKSLVDEEGNDRLKLRVFVTGGGCSGFQYGFTFDEDVAED
CCCCCCCCEEEECCCHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCC
DTIVEREGVSLVVDPMSFQYLAGAEVDYQEGLEGSRFVIKNPNATTTCGCGSSFSI
CCEEECCCCEEEECCCCEEEECCCCCCHHHCCCCCEEEEECCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA