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The map label for this gene is rpoB [H]

Identifier: 77461307

GI number: 77461307

Start: 5714594

End: 5718667

Strand: Reverse

Name: rpoB [H]

Synonym: Pfl01_5086

Alternate gene names: 77461307

Gene position: 5718667-5714594 (Counterclockwise)

Preceding gene: 77461308

Following gene: 77461306

Centisome position: 88.82

GC content: 57.39

Gene sequence:

>4074_bases
ATGGCTTACTCATATACTGAGAAAAAACGTATCCGCAAGGACTTTAGCAAGTTGCCGGACGTCATGGATGTGCCTTACCT
CCTGGCCATCCAGCTGGATTCGTATCGTGAATTCTTGCAAGCGGGAGCGACTAAAGATCAGTTCCGCGACGTGGGCCTGC
ATGCGGCCTTCAAATCCGTTTTCCCGATCATCAGCTACTCCGGCAATGCTGCGCTGGAGTACGTCGGTTATCGCCTGGGC
GAACCGGCATTTGATGTCAAAGAATGCGTATTGCGCGGTGTAACTTTCGCCGTACCTTTGCGGGTAAAAGTGCGCCTGAT
CATTTTCGACAAAGAATCGTCGAACAAAGCGATCAAGGACATCAAAGAGCAAGAAGTCTACATGGGTGAAATCCCATTGA
TGACTGAGAACGGTACCTTCGTAATCAACGGTACCGAGCGTGTTATCGTTTCCCAGCTGCACCGTTCCCCGGGCGTGTTC
TTCGACCACGACCGTGGCAAGACGCACAGCTCCGGCAAGCTGCTGTACTCCGCGCGCATCATTCCTTACCGCGGTTCGTG
GCTGGACTTCGAGTTCGACCCGAAAGACTGCGTATTCGTGCGTATCGACCGTCGTCGCAAGCTGCCGGCCTCGGTACTGC
TGCGCGCGCTCGGTTATACCACCGAGGAAGTGCTGGACGCGTTCTACACTACCAACGTATTCCACGTGAAAGGCGAAGGC
CTGAGCCTGGAGCTGGTACCTCAGCGTCTGCGTGGTGAAGTTGCGGTTCTCGATATCCAGGACGACAAAGGCAAGGTGAT
CGTTGAGCAGGGCCGTCGTATTACTGCCCGCCACATCAACCAGCTGGAAAAAGCCGGGATCAAAGAGCTGGACGTGCCTC
TGGACTACGTTCTGGGTCGTACCACCGCCAAGGCCATCGTGCACCCGGCTACCGGTGAGATCCTGGCAGAGTGCAACACC
GAGCTTTCGACCGAGATCCTGGCGAAAATCGCCAAGGCCGGCGTCGTACGCATCGAAACTCTGTACACCAACGACATCGA
CTGCGGTCCGTTCGTCTCCGACACGCTGAAGATCGACTCCACCAGTAACCAATTGGAAGCGCTGGTCGAGATCTATCGCA
TGATGCGTCCGGGTGAACCGCCAACCAAAGACGCTGCCGAGACCCTGTTCAACAACCTGTTCTTCAGTCCTGAGCGCTAT
GACCTGTCTGCGGTCGGCCGGATGAAGTTCAACCGTCGTATCGGTCGTACCGAGATCGAAGGTTCGGGCGTGCTGTGCAA
GGAAGACATCGTCGCGGTACTGAAGACTCTGGTCGACATCCGTAACGGTAAAGGCATCGTCGACGACATCGACCACCTGG
GTAACCGTCGTGTTCGCTGCGTAGGCGAAATGGCCGAGAACCAGTTCCGCGTTGGCCTGGTACGTGTTGAGCGTGCGGTC
AAAGAGCGTCTGTCGATGGCTGAAAGCGAAGGCCTGATGCCGCAAGATCTGATCAACGCCAAGCCAGTGGCTGCGGCGGT
GAAAGAGTTCTTCGGTTCCAGCCAGCTGTCGCAGTTCATGGACCAGAACAACCCGCTGTCCGAGATCACCCACAAGCGTC
GTGTCTCTGCACTCGGCCCTGGCGGTCTGACTCGTGAGCGCGCGGGCTTCGAAGTCCGTGACGTACACCCGACTCACTAT
GGTCGTGTCTGCCCGATTGAAACGCCGGAAGGTCCGAACATCGGGCTGATCAACTCCCTGGCTGCTTACGCTCGCACCAA
CCAGTACGGCTTCCTCGAGAGCCCGTACCGCGTGGTGAAAGAGGGTGTGGTCACCGACGACATCGTGTTCCTGTCCGCCA
TTGAAGAAGCTGATCACGTGATCGCGCAGGCTTCGGCGACCATGAACGAGCAGAAAGTCCTGATCGATGAACTGGTGGCC
GTGCGTCACCTGAACGAATTCACCGTCAAGGCGCCGGAAGACGTCACCTTGATGGACGTTTCGCCGAAGCAGGTAGTTTC
TGTTGCAGCGTCGCTGATTCCGTTCCTCGAGCATGACGACGCCAACCGTGCGTTGATGGGTTCGAACATGCAGCGTCAGG
CTGTACCAACCCTGCGTGCTGACAAGCCGCTGGTCGGTACCGGCATGGAGCGTAACGTGGCTCGCGACTCCGGCGTTTGC
GTCGTGGCTCGTCGTGGCGGCGTGATCGACTCCGTTGATGCCAGCCGTATCGTGGTTCGTGTTGCTGATGACGAAGTTGA
AACCGGCGAAGCTGGTGTCGACATCTACAACCTGACCAAATACACCCGCTCGAACCAGAACACCTGCATCAACCAGCGTC
CGCTGGTGAGCAAAGGTGATCGCGTTCAGCGTAGCGACATCATGGCCGACGGCCCGTCCACCGACATGGGTGAGCTGGCT
CTGGGTCAGAACATGCGCATCGCGTTCATGGCATGGAACGGCTTCAACTTCGAAGACTCCATCTGCCTTTCCGAGCGTGT
GGTGCAGGAAGACCGCTTCACCACGATCCACATTCAGGAACTGACCTGTGTGGCCCGTGACACCAAGCTTGGCCCAGAGG
AAATCACTGCGGACATCCCGAACGTGGGTGAAGCTGCGCTGAACAAGCTGGACGAAGCCGGTATCGTTTACGTAGGTGCT
GAAGTTGGCGCAGGCGACATCCTGGTAGGCAAGGTCACTCCGAAAGGCGAGACCCAACTGACTCCGGAAGAAAAACTGCT
GCGCGCAATCTTCGGTGAAAAAGCCAGCGACGTTAAAGACACTTCCCTGCGCGTGCCAACGGGCACCAAAGGCACTGTCA
TCGACGTACAGGTCTTCACGCGTGACGGCGTTGAGCGTGATGCTCGTGCACTGTCGATCGAGAAGTCCCAGCTGGACGAG
ATCCGCAAGGATCTGAACGAAGAGTTCCGCATCGTTGAAGGCGCGACCTTCGAGCGTCTGCGTTCCGCTCTGGTAGGCCA
CAAGGCTGAAGGCGGCGCCGGCCTGAAGAAAGGTCAGGACATCACCGACGAAGTACTCGACGGTCTTGAGCATGGTCAGT
GGTTCAAACTGCGCATGGCTGAAGATGCTCTGAACGAGCAGCTCGAGAAGGCTCAGGCCTACATCGTTGATCGTCGCCGT
CTGCTGGACGACAAGTTCGAAGACAAGAAGCGCAAACTGCAGCAGGGCGATGACCTGGCTCCAGGCGTGCTGAAGATCGT
CAAGGTTTACCTGGCAATCCGTCGTCGCATCCAGCCGGGCGACAAGATGGCCGGTCGTCACGGTAACAAAGGTGTGGTCT
CCGTGATCATGCCGGTTGAAGACATGCCGCACGATGCCAATGGCACCCCGGTCGACGTGGTCCTCAACCCGCTGGGCGTA
CCTTCGCGTATGAACGTTGGTCAGATCCTTGAAACCCACCTGGGCCTCGCGGCCAAAGGTCTGGGCGAGAAGATCAACCG
GATGGTCGAAGAGCAGCGCAAAGTCGCTGAACTGCGTACCTTCCTGGACGAGATCTACAACCAGATCGGCGGTCGTAACG
AAGATCTGGACAGCTTCTCCGATCAGGAAATCCTGGATCTGGCGAAGAACCTGCGTGGCGGTGTTCCAATGGCCACTCCA
GTGTTCGACGGTGCCAAGGAAAGCGAAATCAAGGCCATGCTGAAACTGGCAGACCTGCCAGAAAGCGGCCAGATGCAGCT
GACCGACGGCCGTACCGGCAACAAGTTCGAGCGTCCAGTTACCGTTGGCTACATGTACATGCTGAAGCTGAACCACTTGG
TAGACGACAAGATGCACGCGCGTTCTACCGGTTCGTACAGCCTGGTTACCCAGCAGCCGCTGGGTGGTAAGGCGCAGTTC
GGTGGTCAGCGTTTCGGGGAGATGGAGGTCTGGGCACTGGAAGCATACGGTGCTGCTTACACTCTGCAAGAAATGCTCAC
AGTGAAGTCGGACGATGTGAACGGCCGGACCAAGATGTACAAAAACATCGTGGACGGCGATCACCGTATGGAGCCGGGCA
TGCCCGAGTCCTTCAACGTGTTGATCAAGGAAATTCGTTCCCTCGGCATCGATATCGATCTGGAAACCGAATAA

Upstream 100 bases:

>100_bases
CCACCCGATGCGGTGGCGCAAACCATGGGGTTTGCACGATTTTCTGGCTGCTCCCGTCGGGAGGGGCCAAACAAGCAGGT
GACCAAGCTGGGGAACGCTG

Downstream 100 bases:

>100_bases
CACGTGACGCGATCGAGAGCGGGGCAGGATTGCCCGCTCTCTGCTCCGCCAGGAGGAAAGGCCTTGAAAGACCTACTGAA
TTTGCTGAAAAACCAGGGTC

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]

Number of amino acids: Translated: 1357; Mature: 1356

Protein sequence:

>1357_residues
MAYSYTEKKRIRKDFSKLPDVMDVPYLLAIQLDSYREFLQAGATKDQFRDVGLHAAFKSVFPIISYSGNAALEYVGYRLG
EPAFDVKECVLRGVTFAVPLRVKVRLIIFDKESSNKAIKDIKEQEVYMGEIPLMTENGTFVINGTERVIVSQLHRSPGVF
FDHDRGKTHSSGKLLYSARIIPYRGSWLDFEFDPKDCVFVRIDRRRKLPASVLLRALGYTTEEVLDAFYTTNVFHVKGEG
LSLELVPQRLRGEVAVLDIQDDKGKVIVEQGRRITARHINQLEKAGIKELDVPLDYVLGRTTAKAIVHPATGEILAECNT
ELSTEILAKIAKAGVVRIETLYTNDIDCGPFVSDTLKIDSTSNQLEALVEIYRMMRPGEPPTKDAAETLFNNLFFSPERY
DLSAVGRMKFNRRIGRTEIEGSGVLCKEDIVAVLKTLVDIRNGKGIVDDIDHLGNRRVRCVGEMAENQFRVGLVRVERAV
KERLSMAESEGLMPQDLINAKPVAAAVKEFFGSSQLSQFMDQNNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHY
GRVCPIETPEGPNIGLINSLAAYARTNQYGFLESPYRVVKEGVVTDDIVFLSAIEEADHVIAQASATMNEQKVLIDELVA
VRHLNEFTVKAPEDVTLMDVSPKQVVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLRADKPLVGTGMERNVARDSGVC
VVARRGGVIDSVDASRIVVRVADDEVETGEAGVDIYNLTKYTRSNQNTCINQRPLVSKGDRVQRSDIMADGPSTDMGELA
LGQNMRIAFMAWNGFNFEDSICLSERVVQEDRFTTIHIQELTCVARDTKLGPEEITADIPNVGEAALNKLDEAGIVYVGA
EVGAGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPTGTKGTVIDVQVFTRDGVERDARALSIEKSQLDE
IRKDLNEEFRIVEGATFERLRSALVGHKAEGGAGLKKGQDITDEVLDGLEHGQWFKLRMAEDALNEQLEKAQAYIVDRRR
LLDDKFEDKKRKLQQGDDLAPGVLKIVKVYLAIRRRIQPGDKMAGRHGNKGVVSVIMPVEDMPHDANGTPVDVVLNPLGV
PSRMNVGQILETHLGLAAKGLGEKINRMVEEQRKVAELRTFLDEIYNQIGGRNEDLDSFSDQEILDLAKNLRGGVPMATP
VFDGAKESEIKAMLKLADLPESGQMQLTDGRTGNKFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQF
GGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGDHRMEPGMPESFNVLIKEIRSLGIDIDLETE

Sequences:

>Translated_1357_residues
MAYSYTEKKRIRKDFSKLPDVMDVPYLLAIQLDSYREFLQAGATKDQFRDVGLHAAFKSVFPIISYSGNAALEYVGYRLG
EPAFDVKECVLRGVTFAVPLRVKVRLIIFDKESSNKAIKDIKEQEVYMGEIPLMTENGTFVINGTERVIVSQLHRSPGVF
FDHDRGKTHSSGKLLYSARIIPYRGSWLDFEFDPKDCVFVRIDRRRKLPASVLLRALGYTTEEVLDAFYTTNVFHVKGEG
LSLELVPQRLRGEVAVLDIQDDKGKVIVEQGRRITARHINQLEKAGIKELDVPLDYVLGRTTAKAIVHPATGEILAECNT
ELSTEILAKIAKAGVVRIETLYTNDIDCGPFVSDTLKIDSTSNQLEALVEIYRMMRPGEPPTKDAAETLFNNLFFSPERY
DLSAVGRMKFNRRIGRTEIEGSGVLCKEDIVAVLKTLVDIRNGKGIVDDIDHLGNRRVRCVGEMAENQFRVGLVRVERAV
KERLSMAESEGLMPQDLINAKPVAAAVKEFFGSSQLSQFMDQNNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHY
GRVCPIETPEGPNIGLINSLAAYARTNQYGFLESPYRVVKEGVVTDDIVFLSAIEEADHVIAQASATMNEQKVLIDELVA
VRHLNEFTVKAPEDVTLMDVSPKQVVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLRADKPLVGTGMERNVARDSGVC
VVARRGGVIDSVDASRIVVRVADDEVETGEAGVDIYNLTKYTRSNQNTCINQRPLVSKGDRVQRSDIMADGPSTDMGELA
LGQNMRIAFMAWNGFNFEDSICLSERVVQEDRFTTIHIQELTCVARDTKLGPEEITADIPNVGEAALNKLDEAGIVYVGA
EVGAGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPTGTKGTVIDVQVFTRDGVERDARALSIEKSQLDE
IRKDLNEEFRIVEGATFERLRSALVGHKAEGGAGLKKGQDITDEVLDGLEHGQWFKLRMAEDALNEQLEKAQAYIVDRRR
LLDDKFEDKKRKLQQGDDLAPGVLKIVKVYLAIRRRIQPGDKMAGRHGNKGVVSVIMPVEDMPHDANGTPVDVVLNPLGV
PSRMNVGQILETHLGLAAKGLGEKINRMVEEQRKVAELRTFLDEIYNQIGGRNEDLDSFSDQEILDLAKNLRGGVPMATP
VFDGAKESEIKAMLKLADLPESGQMQLTDGRTGNKFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQF
GGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGDHRMEPGMPESFNVLIKEIRSLGIDIDLETE
>Mature_1356_residues
AYSYTEKKRIRKDFSKLPDVMDVPYLLAIQLDSYREFLQAGATKDQFRDVGLHAAFKSVFPIISYSGNAALEYVGYRLGE
PAFDVKECVLRGVTFAVPLRVKVRLIIFDKESSNKAIKDIKEQEVYMGEIPLMTENGTFVINGTERVIVSQLHRSPGVFF
DHDRGKTHSSGKLLYSARIIPYRGSWLDFEFDPKDCVFVRIDRRRKLPASVLLRALGYTTEEVLDAFYTTNVFHVKGEGL
SLELVPQRLRGEVAVLDIQDDKGKVIVEQGRRITARHINQLEKAGIKELDVPLDYVLGRTTAKAIVHPATGEILAECNTE
LSTEILAKIAKAGVVRIETLYTNDIDCGPFVSDTLKIDSTSNQLEALVEIYRMMRPGEPPTKDAAETLFNNLFFSPERYD
LSAVGRMKFNRRIGRTEIEGSGVLCKEDIVAVLKTLVDIRNGKGIVDDIDHLGNRRVRCVGEMAENQFRVGLVRVERAVK
ERLSMAESEGLMPQDLINAKPVAAAVKEFFGSSQLSQFMDQNNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHYG
RVCPIETPEGPNIGLINSLAAYARTNQYGFLESPYRVVKEGVVTDDIVFLSAIEEADHVIAQASATMNEQKVLIDELVAV
RHLNEFTVKAPEDVTLMDVSPKQVVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLRADKPLVGTGMERNVARDSGVCV
VARRGGVIDSVDASRIVVRVADDEVETGEAGVDIYNLTKYTRSNQNTCINQRPLVSKGDRVQRSDIMADGPSTDMGELAL
GQNMRIAFMAWNGFNFEDSICLSERVVQEDRFTTIHIQELTCVARDTKLGPEEITADIPNVGEAALNKLDEAGIVYVGAE
VGAGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPTGTKGTVIDVQVFTRDGVERDARALSIEKSQLDEI
RKDLNEEFRIVEGATFERLRSALVGHKAEGGAGLKKGQDITDEVLDGLEHGQWFKLRMAEDALNEQLEKAQAYIVDRRRL
LDDKFEDKKRKLQQGDDLAPGVLKIVKVYLAIRRRIQPGDKMAGRHGNKGVVSVIMPVEDMPHDANGTPVDVVLNPLGVP
SRMNVGQILETHLGLAAKGLGEKINRMVEEQRKVAELRTFLDEIYNQIGGRNEDLDSFSDQEILDLAKNLRGGVPMATPV
FDGAKESEIKAMLKLADLPESGQMQLTDGRTGNKFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFG
GQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGDHRMEPGMPESFNVLIKEIRSLGIDIDLETE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family [H]

Homologues:

Organism=Homo sapiens, GI33469941, Length=258, Percent_Identity=31.0077519379845, Blast_Score=118, Evalue=5e-26,
Organism=Homo sapiens, GI212286172, Length=258, Percent_Identity=31.0077519379845, Blast_Score=118, Evalue=5e-26,
Organism=Homo sapiens, GI238908503, Length=296, Percent_Identity=30.7432432432432, Blast_Score=118, Evalue=5e-26,
Organism=Homo sapiens, GI238908505, Length=296, Percent_Identity=30.7432432432432, Blast_Score=117, Evalue=5e-26,
Organism=Homo sapiens, GI4505941, Length=302, Percent_Identity=28.1456953642384, Blast_Score=108, Evalue=3e-23,
Organism=Escherichia coli, GI1790419, Length=1360, Percent_Identity=71.7647058823529, Blast_Score=2038, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17552304, Length=247, Percent_Identity=30.3643724696356, Blast_Score=110, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI25144348, Length=247, Percent_Identity=31.1740890688259, Blast_Score=108, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324781, Length=246, Percent_Identity=32.520325203252, Blast_Score=117, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6324725, Length=248, Percent_Identity=32.6612903225806, Blast_Score=115, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6325267, Length=248, Percent_Identity=31.4516129032258, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI17647877, Length=246, Percent_Identity=32.1138211382114, Blast_Score=112, Evalue=1e-24,
Organism=Drosophila melanogaster, GI17136444, Length=247, Percent_Identity=29.5546558704453, Blast_Score=104, Evalue=4e-22,
Organism=Drosophila melanogaster, GI17136446, Length=260, Percent_Identity=30.3846153846154, Blast_Score=102, Evalue=2e-21,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724 [H]

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 150673; Mature: 150542

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYSYTEKKRIRKDFSKLPDVMDVPYLLAIQLDSYREFLQAGATKDQFRDVGLHAAFKSV
CCCCHHHHHHHHHHHHHCCCHHCCCEEEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHH
FPIISYSGNAALEYVGYRLGEPAFDVKECVLRGVTFAVPLRVKVRLIIFDKESSNKAIKD
HHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEEEEEEEEEEECCCCCHHHHH
IKEQEVYMGEIPLMTENGTFVINGTERVIVSQLHRSPGVFFDHDRGKTHSSGKLLYSARI
HHHHHHEECCCCEEECCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEEE
IPYRGSWLDFEFDPKDCVFVRIDRRRKLPASVLLRALGYTTEEVLDAFYTTNVFHVKGEG
EEECCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHCCEEEEECCC
LSLELVPQRLRGEVAVLDIQDDKGKVIVEQGRRITARHINQLEKAGIKELDVPLDYVLGR
EEEEECCHHHCCCEEEEEEECCCCCEEEECCCEEHHHHHHHHHHCCCCCCCCCHHHHHCC
TTAKAIVHPATGEILAECNTELSTEILAKIAKAGVVRIETLYTNDIDCGPFVSDTLKIDS
HHHHHEECCCCCHHHHHCCCHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCCEEECC
TSNQLEALVEIYRMMRPGEPPTKDAAETLFNNLFFSPERYDLSAVGRMKFNRRIGRTEIE
CHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEC
GSGVLCKEDIVAVLKTLVDIRNGKGIVDDIDHLGNRRVRCVGEMAENQFRVGLVRVERAV
CCCCEEHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEHHHHHCCCHHHHHHHHHHHH
KERLSMAESEGLMPQDLINAKPVAAAVKEFFGSSQLSQFMDQNNPLSEITHKRRVSALGP
HHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHCCCC
GGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLAAYARTNQYGFLESPYRVVK
CCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHH
EGVVTDDIVFLSAIEEADHVIAQASATMNEQKVLIDELVAVRHLNEFTVKAPEDVTLMDV
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHEECCCCCEEEEEC
SPKQVVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLRADKPLVGTGMERNVARDSGVC
CHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCEE
VVARRGGVIDSVDASRIVVRVADDEVETGEAGVDIYNLTKYTRSNQNTCINQRPLVSKGD
EEEECCCCEECCCCCEEEEEEECCCCCCCCCCCEEEEHHHHHCCCCCCCCCCCCCCCCCC
RVQRSDIMADGPSTDMGELALGQNMRIAFMAWNGFNFEDSICLSERVVQEDRFTTIHIQE
CCCHHCCCCCCCCCCCHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEH
LTCVARDTKLGPEEITADIPNVGEAALNKLDEAGIVYVGAEVGAGDILVGKVTPKGETQL
HEEEHHCCCCCHHHHHCCCCCCCHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCCCCC
TPEEKLLRAIFGEKASDVKDTSLRVPTGTKGTVIDVQVFTRDGVERDARALSIEKSQLDE
CHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCEEEEEEEECCCCHHHHHHHCCCHHHHHH
IRKDLNEEFRIVEGATFERLRSALVGHKAEGGAGLKKGQDITDEVLDGLEHGQWFKLRMA
HHHHHCHHEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEH
EDALNEQLEKAQAYIVDRRRLLDDKFEDKKRKLQQGDDLAPGVLKIVKVYLAIRRRIQPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
DKMAGRHGNKGVVSVIMPVEDMPHDANGTPVDVVLNPLGVPSRMNVGQILETHLGLAAKG
HHHCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
LGEKINRMVEEQRKVAELRTFLDEIYNQIGGRNEDLDSFSDQEILDLAKNLRGGVPMATP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
VFDGAKESEIKAMLKLADLPESGQMQLTDGRTGNKFERPVTVGYMYMLKLNHLVDDKMHA
CCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCEEHHHHHHHHHHHHHCCHHHH
RSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMY
CCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHH
KNIVDGDHRMEPGMPESFNVLIKEIRSLGIDIDLETE
HHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCC
>Mature Secondary Structure 
AYSYTEKKRIRKDFSKLPDVMDVPYLLAIQLDSYREFLQAGATKDQFRDVGLHAAFKSV
CCCHHHHHHHHHHHHHCCCHHCCCEEEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHH
FPIISYSGNAALEYVGYRLGEPAFDVKECVLRGVTFAVPLRVKVRLIIFDKESSNKAIKD
HHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEEEEEEEEEEECCCCCHHHHH
IKEQEVYMGEIPLMTENGTFVINGTERVIVSQLHRSPGVFFDHDRGKTHSSGKLLYSARI
HHHHHHEECCCCEEECCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEEE
IPYRGSWLDFEFDPKDCVFVRIDRRRKLPASVLLRALGYTTEEVLDAFYTTNVFHVKGEG
EEECCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHCCEEEEECCC
LSLELVPQRLRGEVAVLDIQDDKGKVIVEQGRRITARHINQLEKAGIKELDVPLDYVLGR
EEEEECCHHHCCCEEEEEEECCCCCEEEECCCEEHHHHHHHHHHCCCCCCCCCHHHHHCC
TTAKAIVHPATGEILAECNTELSTEILAKIAKAGVVRIETLYTNDIDCGPFVSDTLKIDS
HHHHHEECCCCCHHHHHCCCHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCCEEECC
TSNQLEALVEIYRMMRPGEPPTKDAAETLFNNLFFSPERYDLSAVGRMKFNRRIGRTEIE
CHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEC
GSGVLCKEDIVAVLKTLVDIRNGKGIVDDIDHLGNRRVRCVGEMAENQFRVGLVRVERAV
CCCCEEHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEHHHHHCCCHHHHHHHHHHHH
KERLSMAESEGLMPQDLINAKPVAAAVKEFFGSSQLSQFMDQNNPLSEITHKRRVSALGP
HHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHCCCC
GGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLAAYARTNQYGFLESPYRVVK
CCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHH
EGVVTDDIVFLSAIEEADHVIAQASATMNEQKVLIDELVAVRHLNEFTVKAPEDVTLMDV
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHEECCCCCEEEEEC
SPKQVVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLRADKPLVGTGMERNVARDSGVC
CHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCEE
VVARRGGVIDSVDASRIVVRVADDEVETGEAGVDIYNLTKYTRSNQNTCINQRPLVSKGD
EEEECCCCEECCCCCEEEEEEECCCCCCCCCCCEEEEHHHHHCCCCCCCCCCCCCCCCCC
RVQRSDIMADGPSTDMGELALGQNMRIAFMAWNGFNFEDSICLSERVVQEDRFTTIHIQE
CCCHHCCCCCCCCCCCHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEH
LTCVARDTKLGPEEITADIPNVGEAALNKLDEAGIVYVGAEVGAGDILVGKVTPKGETQL
HEEEHHCCCCCHHHHHCCCCCCCHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCCCCC
TPEEKLLRAIFGEKASDVKDTSLRVPTGTKGTVIDVQVFTRDGVERDARALSIEKSQLDE
CHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCEEEEEEEECCCCHHHHHHHCCCHHHHHH
IRKDLNEEFRIVEGATFERLRSALVGHKAEGGAGLKKGQDITDEVLDGLEHGQWFKLRMA
HHHHHCHHEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEH
EDALNEQLEKAQAYIVDRRRLLDDKFEDKKRKLQQGDDLAPGVLKIVKVYLAIRRRIQPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
DKMAGRHGNKGVVSVIMPVEDMPHDANGTPVDVVLNPLGVPSRMNVGQILETHLGLAAKG
HHHCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
LGEKINRMVEEQRKVAELRTFLDEIYNQIGGRNEDLDSFSDQEILDLAKNLRGGVPMATP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
VFDGAKESEIKAMLKLADLPESGQMQLTDGRTGNKFERPVTVGYMYMLKLNHLVDDKMHA
CCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCEEHHHHHHHHHHHHHCCHHHH
RSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMY
CCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHH
KNIVDGDHRMEPGMPESFNVLIKEIRSLGIDIDLETE
HHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA