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The map label for this gene is 77461139

Identifier: 77461139

GI number: 77461139

Start: 5540845

End: 5541765

Strand: Direct

Name: 77461139

Synonym: Pfl01_4918

Alternate gene names: NA

Gene position: 5540845-5541765 (Clockwise)

Preceding gene: 77461135

Following gene: 77461140

Centisome position: 86.06

GC content: 63.52

Gene sequence:

>921_bases
ATGCCATTGCCGTTGATCTACCACGAAGACTACAGCCCCGAGTTTCCGGCGGATCACCGCTTTCCCATGGACAAGTTCCG
CCTGCTGCGCGATCACCTGGTGGACAGCGGCCTGACCCGCGACGAAGACCTGCTGCGCCCTGAACTGTGCCCTGCCGACA
TTCTCGCCCTGGCCCATGACCGCAGTTATATCGAGCGCTACATGAGTGGCGAGTTGTCCCGCGAAGACCAGCGGCGCCTC
GGTCTGCCGTGGAACGAAGCGCTGGCGCGACGCACGGTGCGGGCGGTCGGCGGTTCGATTCTGGCAGCGGAAAAAGCCCT
GGAACATGGCCTGGCCTGTCACCTCGCCGGCGGCACCCATCACGCCCACTACGACTACCCCGCCGGGTTCTGCATCTTCA
ATGACCTGGCGATCATCAGCCACTACCTGCTGCAAAGCGGCCGGGTGAACCGGGTGCTGATCTTCGACTGCGACGTGCAT
CAGGGCGACGGCACTGCACGAATTCTGCACAACACCCCGGAAGCGATCACCGTTTCCCTGCACTGCGAGAAGAACTTTCC
TGCACGCAAGGCCGAAAGCGACTGGGACATTCCGCTGCCCAACGGCATGGGCGACGCCGACTACTTGAAGGTTGTCGATG
ACGCGCTCAACTATCTGCTGCCGCTGTATCAGCCGGATCTGGTGCTGTACGACGCCGGCGTCGACGTGCACAAGGACGAC
GCCCTCGGTTATCTGCAACTGACCGACGAAGGCGTCGCCGCCCGCGATGAAAGCGTGATGCGCCACTGCCTGGGCCGCGA
CATCCCGGTGGTCGGGGTGATCGGCGGTGGTTACAGCAAGGATCGCCACGCCCTCGCCCGCCGTCACGGGATCCTGCATC
ACAGTGCGCAGCGCGTCTGGCAGTCATCGGGTTGTCATTGA

Upstream 100 bases:

>100_bases
TCAAGTATCGGCTCCATCGTGCCCCTCCGTTTCCATGCCGCAAGTCTACATCGCTGGTAGGCTTTGCACTCTTTCCTACA
GCCTTTATGAATAGTCCGCC

Downstream 100 bases:

>100_bases
GTTGTGCTGCGTTACCCACAATGGCTGTGGAACGGCCTGTGGATAACCTGAGCGAAAGGGACTACAGCCCATGCTGAACA
TGGCCTGCAGCGCACTGGTT

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MPLPLIYHEDYSPEFPADHRFPMDKFRLLRDHLVDSGLTRDEDLLRPELCPADILALAHDRSYIERYMSGELSREDQRRL
GLPWNEALARRTVRAVGGSILAAEKALEHGLACHLAGGTHHAHYDYPAGFCIFNDLAIISHYLLQSGRVNRVLIFDCDVH
QGDGTARILHNTPEAITVSLHCEKNFPARKAESDWDIPLPNGMGDADYLKVVDDALNYLLPLYQPDLVLYDAGVDVHKDD
ALGYLQLTDEGVAARDESVMRHCLGRDIPVVGVIGGGYSKDRHALARRHGILHHSAQRVWQSSGCH

Sequences:

>Translated_306_residues
MPLPLIYHEDYSPEFPADHRFPMDKFRLLRDHLVDSGLTRDEDLLRPELCPADILALAHDRSYIERYMSGELSREDQRRL
GLPWNEALARRTVRAVGGSILAAEKALEHGLACHLAGGTHHAHYDYPAGFCIFNDLAIISHYLLQSGRVNRVLIFDCDVH
QGDGTARILHNTPEAITVSLHCEKNFPARKAESDWDIPLPNGMGDADYLKVVDDALNYLLPLYQPDLVLYDAGVDVHKDD
ALGYLQLTDEGVAARDESVMRHCLGRDIPVVGVIGGGYSKDRHALARRHGILHHSAQRVWQSSGCH
>Mature_305_residues
PLPLIYHEDYSPEFPADHRFPMDKFRLLRDHLVDSGLTRDEDLLRPELCPADILALAHDRSYIERYMSGELSREDQRRLG
LPWNEALARRTVRAVGGSILAAEKALEHGLACHLAGGTHHAHYDYPAGFCIFNDLAIISHYLLQSGRVNRVLIFDCDVHQ
GDGTARILHNTPEAITVSLHCEKNFPARKAESDWDIPLPNGMGDADYLKVVDDALNYLLPLYQPDLVLYDAGVDVHKDDA
LGYLQLTDEGVAARDESVMRHCLGRDIPVVGVIGGGYSKDRHALARRHGILHHSAQRVWQSSGCH

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI217272877, Length=297, Percent_Identity=28.2828282828283, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI209862883, Length=272, Percent_Identity=29.7794117647059, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI13128860, Length=277, Percent_Identity=28.5198555956679, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI293336691, Length=251, Percent_Identity=28.6852589641434, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI13128864, Length=177, Percent_Identity=34.4632768361582, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI8923769, Length=295, Percent_Identity=24.7457627118644, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI148539870, Length=175, Percent_Identity=30.8571428571429, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI169234807, Length=175, Percent_Identity=30.8571428571429, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI13128862, Length=283, Percent_Identity=27.9151943462898, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI62750347, Length=174, Percent_Identity=31.6091954022989, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI62750349, Length=174, Percent_Identity=31.6091954022989, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI17158039, Length=174, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI30795204, Length=174, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI30795202, Length=174, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI153085395, Length=175, Percent_Identity=29.7142857142857, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI20070354, Length=192, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI262073092, Length=229, Percent_Identity=26.2008733624454, Blast_Score=65, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI193207430, Length=308, Percent_Identity=27.2727272727273, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17537347, Length=264, Percent_Identity=30.6818181818182, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17508561, Length=282, Percent_Identity=26.9503546099291, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17561978, Length=277, Percent_Identity=25.9927797833935, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17540332, Length=176, Percent_Identity=30.6818181818182, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193206283, Length=176, Percent_Identity=30.6818181818182, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17540334, Length=176, Percent_Identity=30.6818181818182, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193209491, Length=218, Percent_Identity=26.605504587156, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17534739, Length=197, Percent_Identity=29.4416243654822, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25154020, Length=201, Percent_Identity=28.8557213930348, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25154022, Length=273, Percent_Identity=27.1062271062271, Blast_Score=71, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6321244, Length=288, Percent_Identity=28.125, Blast_Score=90, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6323999, Length=289, Percent_Identity=26.643598615917, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6324307, Length=244, Percent_Identity=27.0491803278689, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6325325, Length=182, Percent_Identity=27.4725274725275, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24649807, Length=292, Percent_Identity=29.7945205479452, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI281360899, Length=277, Percent_Identity=28.8808664259928, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24642142, Length=270, Percent_Identity=29.2592592592593, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24642144, Length=270, Percent_Identity=29.2592592592593, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24642146, Length=270, Percent_Identity=29.2592592592593, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24657891, Length=277, Percent_Identity=28.8808664259928, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644244, Length=290, Percent_Identity=26.551724137931, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI281360801, Length=204, Percent_Identity=27.4509803921569, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24641720, Length=202, Percent_Identity=27.7227722772277, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI281360799, Length=202, Percent_Identity=27.7227722772277, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 34289; Mature: 34158

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLPLIYHEDYSPEFPADHRFPMDKFRLLRDHLVDSGLTRDEDLLRPELCPADILALAHD
CCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHH
RSYIERYMSGELSREDQRRLGLPWNEALARRTVRAVGGSILAAEKALEHGLACHLAGGTH
HHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEECCCCC
HAHYDYPAGFCIFNDLAIISHYLLQSGRVNRVLIFDCDVHQGDGTARILHNTPEAITVSL
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEECCCCEEEEEE
HCEKNFPARKAESDWDIPLPNGMGDADYLKVVDDALNYLLPLYQPDLVLYDAGVDVHKDD
EECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEECCC
ALGYLQLTDEGVAARDESVMRHCLGRDIPVVGVIGGGYSKDRHALARRHGILHHSAQRVW
CEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
QSSGCH
HHCCCC
>Mature Secondary Structure 
PLPLIYHEDYSPEFPADHRFPMDKFRLLRDHLVDSGLTRDEDLLRPELCPADILALAHD
CCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHH
RSYIERYMSGELSREDQRRLGLPWNEALARRTVRAVGGSILAAEKALEHGLACHLAGGTH
HHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEECCCCC
HAHYDYPAGFCIFNDLAIISHYLLQSGRVNRVLIFDCDVHQGDGTARILHNTPEAITVSL
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEECCCCEEEEEE
HCEKNFPARKAESDWDIPLPNGMGDADYLKVVDDALNYLLPLYQPDLVLYDAGVDVHKDD
EECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEECCC
ALGYLQLTDEGVAARDESVMRHCLGRDIPVVGVIGGGYSKDRHALARRHGILHHSAQRVW
CEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
QSSGCH
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7678591 [H]