Click here to switch to the map view.

The map label for this gene is pilC [H]

Identifier: 77461042

GI number: 77461042

Start: 5441417

End: 5442634

Strand: Direct

Name: pilC [H]

Synonym: Pfl01_4821

Alternate gene names: 77461042

Gene position: 5441417-5442634 (Clockwise)

Preceding gene: 77461041

Following gene: 77461043

Centisome position: 84.51

GC content: 61.49

Gene sequence:

>1218_bases
ATGGCCGTCAAGGCAGCGAAAATCAGTGTCTATGCCTGGGAAGGCACGGACCGCAAAGGCAGCAAGGTGACCGGCGAGCT
GAGCGGCCAGAACCCCGCGCTGGTCAAGGCCCAATTGCGCAAGCAGGGCATCAACCCCGGCAAGGTGCGCAAGAAATCCG
CCTCGTTGCTGAGCTTCGGCAAGCGCATCAAGGCCCAGGACATTGCCCTCTTCACCCGGCAGATGGCGACCATGATGAAG
GCCGGCGTGCCGCTGTTGCAGTCGTTCGACATCATTGGCGAAGGCTTCGAAAACCCGGCCATGCGCAAGCTGGTCGACGA
GGTGAAACAGGAGGTCGCCGCCGGTAACAGTTTCGCCGCCGCGCTGCGCAAGAAACCGCAATATTTCGACGAGTTGTACT
GCAACCTGGTGGATGCCGGCGAGCAGTCCGGCGCCCTCGACACCCTGCTGGAGCGGGTCGCGACCTACAAAGAAAAGAGC
GAAAGCCTCAAGGCCAAGATCAAGAAGGCCATGACCTACCCGTCGGCCGTGGTGCTGGTGGCAGCGGTGGTTACCGGGAT
TCTGCTGGTCAAGGTGGTGCCGCAGTTCCAGTCGGTGTTCTCTGGCTTCGGTGCCGAACTGCCAGCCTTCACGTTGATGG
TGATCAGCCTGTCCGAATTCATGCAGCAATGGTGGTGGGCGATTCTCGGTTTGCTGGTGGCCAGTTTTTTCGGCACCCGC
CATGCCCTGAAAAAATCCCAGGCGCTGCGCGACCGGCGTGACGCCTGGTTTCTCAAGCTGCCGCTGGTGGGCACATTGAT
GTACAAGTCCGCCGTGGCGCGGTTTGCCCGGACCCTGTCGACCACCTTCGCGGCCGGCGTGCCACTGGTGGAAGCACTGG
ATTCGGTGGCCGGGGCCACCGGCAACGTAGTGTTCAAGCGCGCCGTGTTGCGCATCCGTCAGGACGTTTCCACCGGCATG
CAGCTGAATTTCTCGATGCGCTCCACCGGCATCTTTCCGAACATGGCGGTGCAGATGACCGCCATCGGCGAAGAGTCCGG
CGCACTGGACGAGATGCTCGACAAGGTCGCAGGTTTCTATGAGGACGAGGTGGACAACATGGTCGACAACCTCACCAGCC
TGATGGAGCCGTTCATCATGGTGGTGCTCGGGGTGATCGTCGGCGGTCTGGTGGTGGCGATGTACCTGCCGATCTTCCAA
CTCGGCTCAGCGATCTGA

Upstream 100 bases:

>100_bases
GCCGGGACGGCTTCAACGACCTGCGCACCTCGGGCCTGATCAAAGCCATGCAAGGCATCACCAGCCTTGAAGAAATCAAC
CGGGTCACCAAGGACTGAAC

Downstream 100 bases:

>100_bases
CATGCCTATCGACGAACTCTTCAGCCTGTATCCGCTGGCCTTTGTCTTCACCGCCCTGCTGCTGGGGCTGGTGGTCGGCA
GTTTCCTCAACGTGTTGATC

Product: type II secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MAVKAAKISVYAWEGTDRKGSKVTGELSGQNPALVKAQLRKQGINPGKVRKKSASLLSFGKRIKAQDIALFTRQMATMMK
AGVPLLQSFDIIGEGFENPAMRKLVDEVKQEVAAGNSFAAALRKKPQYFDELYCNLVDAGEQSGALDTLLERVATYKEKS
ESLKAKIKKAMTYPSAVVLVAAVVTGILLVKVVPQFQSVFSGFGAELPAFTLMVISLSEFMQQWWWAILGLLVASFFGTR
HALKKSQALRDRRDAWFLKLPLVGTLMYKSAVARFARTLSTTFAAGVPLVEALDSVAGATGNVVFKRAVLRIRQDVSTGM
QLNFSMRSTGIFPNMAVQMTAIGEESGALDEMLDKVAGFYEDEVDNMVDNLTSLMEPFIMVVLGVIVGGLVVAMYLPIFQ
LGSAI

Sequences:

>Translated_405_residues
MAVKAAKISVYAWEGTDRKGSKVTGELSGQNPALVKAQLRKQGINPGKVRKKSASLLSFGKRIKAQDIALFTRQMATMMK
AGVPLLQSFDIIGEGFENPAMRKLVDEVKQEVAAGNSFAAALRKKPQYFDELYCNLVDAGEQSGALDTLLERVATYKEKS
ESLKAKIKKAMTYPSAVVLVAAVVTGILLVKVVPQFQSVFSGFGAELPAFTLMVISLSEFMQQWWWAILGLLVASFFGTR
HALKKSQALRDRRDAWFLKLPLVGTLMYKSAVARFARTLSTTFAAGVPLVEALDSVAGATGNVVFKRAVLRIRQDVSTGM
QLNFSMRSTGIFPNMAVQMTAIGEESGALDEMLDKVAGFYEDEVDNMVDNLTSLMEPFIMVVLGVIVGGLVVAMYLPIFQ
LGSAI
>Mature_404_residues
AVKAAKISVYAWEGTDRKGSKVTGELSGQNPALVKAQLRKQGINPGKVRKKSASLLSFGKRIKAQDIALFTRQMATMMKA
GVPLLQSFDIIGEGFENPAMRKLVDEVKQEVAAGNSFAAALRKKPQYFDELYCNLVDAGEQSGALDTLLERVATYKEKSE
SLKAKIKKAMTYPSAVVLVAAVVTGILLVKVVPQFQSVFSGFGAELPAFTLMVISLSEFMQQWWWAILGLLVASFFGTRH
ALKKSQALRDRRDAWFLKLPLVGTLMYKSAVARFARTLSTTFAAGVPLVEALDSVAGATGNVVFKRAVLRIRQDVSTGMQ
LNFSMRSTGIFPNMAVQMTAIGEESGALDEMLDKVAGFYEDEVDNMVDNLTSLMEPFIMVVLGVIVGGLVVAMYLPIFQL
GSAI

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=396, Percent_Identity=30.050505050505, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1786295, Length=407, Percent_Identity=28.2555282555283, Blast_Score=169, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 44105; Mature: 43974

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVKAAKISVYAWEGTDRKGSKVTGELSGQNPALVKAQLRKQGINPGKVRKKSASLLSFG
CCCEEEEEEEEEECCCCCCCCCCEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHH
KRIKAQDIALFTRQMATMMKAGVPLLQSFDIIGEGFENPAMRKLVDEVKQEVAAGNSFAA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHH
ALRKKPQYFDELYCNLVDAGEQSGALDTLLERVATYKEKSESLKAKIKKAMTYPSAVVLV
HHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
AAVVTGILLVKVVPQFQSVFSGFGAELPAFTLMVISLSEFMQQWWWAILGLLVASFFGTR
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HALKKSQALRDRRDAWFLKLPLVGTLMYKSAVARFARTLSTTFAAGVPLVEALDSVAGAT
HHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
GNVVFKRAVLRIRQDVSTGMQLNFSMRSTGIFPNMAVQMTAIGEESGALDEMLDKVAGFY
CHHHHHHHHHHHHHHHHCCCEEEEEHHCCCCCCCHHEEEEECCCCCCCHHHHHHHHHHHH
EDEVDNMVDNLTSLMEPFIMVVLGVIVGGLVVAMYLPIFQLGSAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AVKAAKISVYAWEGTDRKGSKVTGELSGQNPALVKAQLRKQGINPGKVRKKSASLLSFG
CCEEEEEEEEEECCCCCCCCCCEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHH
KRIKAQDIALFTRQMATMMKAGVPLLQSFDIIGEGFENPAMRKLVDEVKQEVAAGNSFAA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHH
ALRKKPQYFDELYCNLVDAGEQSGALDTLLERVATYKEKSESLKAKIKKAMTYPSAVVLV
HHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
AAVVTGILLVKVVPQFQSVFSGFGAELPAFTLMVISLSEFMQQWWWAILGLLVASFFGTR
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HALKKSQALRDRRDAWFLKLPLVGTLMYKSAVARFARTLSTTFAAGVPLVEALDSVAGAT
HHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
GNVVFKRAVLRIRQDVSTGMQLNFSMRSTGIFPNMAVQMTAIGEESGALDEMLDKVAGFY
CHHHHHHHHHHHHHHHHCCCEEEEEHHCCCCCCCHHEEEEECCCCCCCHHHHHHHHHHHH
EDEVDNMVDNLTSLMEPFIMVVLGVIVGGLVVAMYLPIFQLGSAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]