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The map label for this gene is zraR [H]

Identifier: 77461029

GI number: 77461029

Start: 5423593

End: 5425029

Strand: Direct

Name: zraR [H]

Synonym: Pfl01_4808

Alternate gene names: 77461029

Gene position: 5423593-5425029 (Clockwise)

Preceding gene: 77461028

Following gene: 77461030

Centisome position: 84.24

GC content: 61.73

Gene sequence:

>1437_bases
ATGCCGCACATTTTGATCGTCGAAGACGAAACCATTATCCGCTCCGCCTTGCGCCGCCTGCTGGAACGCAACCAGTACCA
GGTCAGCGAAGCCGGTTCAGTGCAGGAAGCACAAGAACGCTTCAGTATTCCCACATTCGATCTGATCGTCAGCGACCTGC
GTCTGCCGGGTGCTCCGGGCACCGAGCTGATCAAGCTCGGCCAGGGCACGCCGGTGCTGATCATGACCAGCTACGCCAGC
CTGCGCTCGGCGGTCGACTCGATGAAGATGGGCGCGGTGGATTACATCGCCAAGCCTTTCGACCACGATGAAATGCTTCA
GGCTGTCGCGCGGATCCTGCGCGATCGCCAGTCGGCGCCTGCTGCCGGCGAAGCAGCTCCCGCGAAATCGGCCAATGGCA
GCGGCAAATCCGCCATCGACAACAGCAATGGCGAGATCGGCATCATCGGTTCGTGTCCGCCGATGCAGGATCTTTACGGC
AAGATCCGTAAAGTCGCGCCGACCGATTCCAACGTATTGATCCAGGGTGAGTCCGGTACCGGTAAAGAGCTGGTGGCCCG
TGCCCTGCACAACCTGTCGAAACGCGCCAAGGCACCGATGATCTCGGTGAACTGCGCCGCCATTCCGGAAAGCCTGATCG
AGTCCGAACTGTTCGGCCACGAGAAAGGCGCGTTCACCGGTGCCAGCGCCGGTCGCGCCGGTCTGGTGGAAGCGGCGGAC
GGCGGCACGCTGTTCCTCGACGAAATTGGCGAGTTGCCACTGGAAGCTCAGGCTCGTTTGCTGCGTGTCTTGCAGGAAGG
CGAAATTCGCCGGGTTGGCTCGGTTCAGTCGCAGAAAGTCGATGTCCGGTTGATCGCCGCGACCCACCGCGACCTCAAGA
GCCTGGCGAAAATCGGCCAGTTCCGTGAAGACTTGTACTACCGCCTCCATGTGATCGCGTTGAAACTGCCGGCCCTGCGC
GAGCGAGGCGCCGACGTCAACGAAATCGCCAATGCGTTCCTTGCTCGCCAGAGCGCACGCATCAACCGCACCGACCTGAA
ATTTGCCGCCGATGCCGAACAGGCGATCCGGCACTATTCCTGGCCGGGTAACGTACGGGAGCTGGAAAACGCCGTCGAGC
GCGCCGTGATTCTGAGCGAAAGCCCGGAAATCTCTGCCGACCTGCTGGGCATCGACATCGAGCTGGGTGATCTGGAGGAC
GACGAATTCATCGGCCTGCCGGCGCAACCGGCCGGTAACGCCAGCAACAGCAGCCACGAGCCGACCGAAGACCTATCACT
GGAAGACTACTTCCAGCATTTCGTGCTCGAGCATCAGGATCACATGACCGAGACCGAACTGGCGCGCAAACTGGGCGTCA
GCCGCAAATGCCTGTGGGAGCGTCGTCAGCGTCTGGGCATTCCACGGCGCAAGACCGGGGTCGCCAGCGAGAGCTGA

Upstream 100 bases:

>100_bases
GATGTTCAGAGCCAGCGCGGCACCCGTATCCGGGTGACATTGCCGCGCCATGTCGAAGCGACGTCCGCTGTGAACTGAGA
CCGTCGAGAGTATCGAATCA

Downstream 100 bases:

>100_bases
ACGTTACCTGTCGAGTGTGCGGGTTACCGTTGAAGAGGTGAAAAAACTGTTACCTCAGTCTTTTCACGTAACAGAAGCCG
GGGTTATCGGTAACGAAACC

Product: two-component response regulator CbrB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MPHILIVEDETIIRSALRRLLERNQYQVSEAGSVQEAQERFSIPTFDLIVSDLRLPGAPGTELIKLGQGTPVLIMTSYAS
LRSAVDSMKMGAVDYIAKPFDHDEMLQAVARILRDRQSAPAAGEAAPAKSANGSGKSAIDNSNGEIGIIGSCPPMQDLYG
KIRKVAPTDSNVLIQGESGTGKELVARALHNLSKRAKAPMISVNCAAIPESLIESELFGHEKGAFTGASAGRAGLVEAAD
GGTLFLDEIGELPLEAQARLLRVLQEGEIRRVGSVQSQKVDVRLIAATHRDLKSLAKIGQFREDLYYRLHVIALKLPALR
ERGADVNEIANAFLARQSARINRTDLKFAADAEQAIRHYSWPGNVRELENAVERAVILSESPEISADLLGIDIELGDLED
DEFIGLPAQPAGNASNSSHEPTEDLSLEDYFQHFVLEHQDHMTETELARKLGVSRKCLWERRQRLGIPRRKTGVASES

Sequences:

>Translated_478_residues
MPHILIVEDETIIRSALRRLLERNQYQVSEAGSVQEAQERFSIPTFDLIVSDLRLPGAPGTELIKLGQGTPVLIMTSYAS
LRSAVDSMKMGAVDYIAKPFDHDEMLQAVARILRDRQSAPAAGEAAPAKSANGSGKSAIDNSNGEIGIIGSCPPMQDLYG
KIRKVAPTDSNVLIQGESGTGKELVARALHNLSKRAKAPMISVNCAAIPESLIESELFGHEKGAFTGASAGRAGLVEAAD
GGTLFLDEIGELPLEAQARLLRVLQEGEIRRVGSVQSQKVDVRLIAATHRDLKSLAKIGQFREDLYYRLHVIALKLPALR
ERGADVNEIANAFLARQSARINRTDLKFAADAEQAIRHYSWPGNVRELENAVERAVILSESPEISADLLGIDIELGDLED
DEFIGLPAQPAGNASNSSHEPTEDLSLEDYFQHFVLEHQDHMTETELARKLGVSRKCLWERRQRLGIPRRKTGVASES
>Mature_477_residues
PHILIVEDETIIRSALRRLLERNQYQVSEAGSVQEAQERFSIPTFDLIVSDLRLPGAPGTELIKLGQGTPVLIMTSYASL
RSAVDSMKMGAVDYIAKPFDHDEMLQAVARILRDRQSAPAAGEAAPAKSANGSGKSAIDNSNGEIGIIGSCPPMQDLYGK
IRKVAPTDSNVLIQGESGTGKELVARALHNLSKRAKAPMISVNCAAIPESLIESELFGHEKGAFTGASAGRAGLVEAADG
GTLFLDEIGELPLEAQARLLRVLQEGEIRRVGSVQSQKVDVRLIAATHRDLKSLAKIGQFREDLYYRLHVIALKLPALRE
RGADVNEIANAFLARQSARINRTDLKFAADAEQAIRHYSWPGNVRELENAVERAVILSESPEISADLLGIDIELGDLEDD
EFIGLPAQPAGNASNSSHEPTEDLSLEDYFQHFVLEHQDHMTETELARKLGVSRKCLWERRQRLGIPRRKTGVASES

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=466, Percent_Identity=42.274678111588, Blast_Score=331, Evalue=5e-92,
Organism=Escherichia coli, GI1788550, Length=475, Percent_Identity=41.2631578947368, Blast_Score=330, Evalue=8e-92,
Organism=Escherichia coli, GI1790299, Length=479, Percent_Identity=40.5010438413361, Blast_Score=303, Evalue=2e-83,
Organism=Escherichia coli, GI1788905, Length=392, Percent_Identity=42.8571428571429, Blast_Score=291, Evalue=8e-80,
Organism=Escherichia coli, GI87082117, Length=344, Percent_Identity=45.0581395348837, Blast_Score=254, Evalue=8e-69,
Organism=Escherichia coli, GI1789087, Length=242, Percent_Identity=52.4793388429752, Blast_Score=252, Evalue=4e-68,
Organism=Escherichia coli, GI87082152, Length=234, Percent_Identity=54.7008547008547, Blast_Score=248, Evalue=9e-67,
Organism=Escherichia coli, GI1789233, Length=238, Percent_Identity=49.1596638655462, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1786524, Length=331, Percent_Identity=41.6918429003021, Blast_Score=219, Evalue=4e-58,
Organism=Escherichia coli, GI87081872, Length=286, Percent_Identity=42.6573426573427, Blast_Score=211, Evalue=7e-56,
Organism=Escherichia coli, GI1787583, Length=330, Percent_Identity=36.969696969697, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1789828, Length=257, Percent_Identity=36.1867704280156, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI87081858, Length=222, Percent_Identity=35.5855855855856, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786599, Length=117, Percent_Identity=34.1880341880342, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786911, Length=125, Percent_Identity=37.6, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 52172; Mature: 52041

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHILIVEDETIIRSALRRLLERNQYQVSEAGSVQEAQERFSIPTFDLIVSDLRLPGAPG
CCCEEEECCHHHHHHHHHHHHHCCCEEHHHCCCHHHHHHHHCCCHHHHHHHHHCCCCCCC
TELIKLGQGTPVLIMTSYASLRSAVDSMKMGAVDYIAKPFDHDEMLQAVARILRDRQSAP
HHHEEECCCCCEEEEECHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
AAGEAAPAKSANGSGKSAIDNSNGEIGIIGSCPPMQDLYGKIRKVAPTDSNVLIQGESGT
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCEEEECCCCC
GKELVARALHNLSKRAKAPMISVNCAAIPESLIESELFGHEKGAFTGASAGRAGLVEAAD
CHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECC
GGTLFLDEIGELPLEAQARLLRVLQEGEIRRVGSVQSQKVDVRLIAATHRDLKSLAKIGQ
CCEEEHHHHCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHH
FREDLYYRLHVIALKLPALRERGADVNEIANAFLARQSARINRTDLKFAADAEQAIRHYS
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHCC
WPGNVRELENAVERAVILSESPEISADLLGIDIELGDLEDDEFIGLPAQPAGNASNSSHE
CCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCEECCCCCCCCCCCCCCCC
PTEDLSLEDYFQHFVLEHQDHMTETELARKLGVSRKCLWERRQRLGIPRRKTGVASES
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHCCCCCHHCCCCCCC
>Mature Secondary Structure 
PHILIVEDETIIRSALRRLLERNQYQVSEAGSVQEAQERFSIPTFDLIVSDLRLPGAPG
CCEEEECCHHHHHHHHHHHHHCCCEEHHHCCCHHHHHHHHCCCHHHHHHHHHCCCCCCC
TELIKLGQGTPVLIMTSYASLRSAVDSMKMGAVDYIAKPFDHDEMLQAVARILRDRQSAP
HHHEEECCCCCEEEEECHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
AAGEAAPAKSANGSGKSAIDNSNGEIGIIGSCPPMQDLYGKIRKVAPTDSNVLIQGESGT
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCEEEECCCCC
GKELVARALHNLSKRAKAPMISVNCAAIPESLIESELFGHEKGAFTGASAGRAGLVEAAD
CHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECC
GGTLFLDEIGELPLEAQARLLRVLQEGEIRRVGSVQSQKVDVRLIAATHRDLKSLAKIGQ
CCEEEHHHHCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHH
FREDLYYRLHVIALKLPALRERGADVNEIANAFLARQSARINRTDLKFAADAEQAIRHYS
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHCC
WPGNVRELENAVERAVILSESPEISADLLGIDIELGDLEDDEFIGLPAQPAGNASNSSHE
CCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCEECCCCCCCCCCCCCCCC
PTEDLSLEDYFQHFVLEHQDHMTETELARKLGVSRKCLWERRQRLGIPRRKTGVASES
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]