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The map label for this gene is hlyB [H]

Identifier: 77460936

GI number: 77460936

Start: 5323594

End: 5325735

Strand: Direct

Name: hlyB [H]

Synonym: Pfl01_4715

Alternate gene names: 77460936

Gene position: 5323594-5325735 (Clockwise)

Preceding gene: 77460934

Following gene: 77460940

Centisome position: 82.68

GC content: 61.11

Gene sequence:

>2142_bases
ATGAAGTTCAAGTCGATCCAGTTTTCCGTGGCAGCCCTGGCCGGCGCCATCGTGCTCAGCGTAGTCGCTGCGCTGGTGCT
GTATGCGCTGTTCTCCGGTGCCCGCACCCAGGAAATGGTCCAGCAACGGACTCAGGCCCAGTTCGAGCAAGTCATCGAAC
AGCGCCTGACGTCGCTGGCGCAGACTCAGGTCAGCCAGATCCAGCGCGAACTGGAAGCGCCGCTGCTGATTGCCGGCGGA
CTGGTGCGCGTCAACGCCCTGCTCGGCACACCGGGCGCCGACGGCCAGCCACGCCTGAACGTCAGCCGCGAGCAACTGAT
CAGCCTGATCAAGGAAAACGTCGAGAAGAATCCGAAGATTCTCGGCACCTACATCGGCTGGGAAAAGAACGCACTGGACC
ACAATGACGCGGCCTACGTCGGCACTCAGGTTGTCGGGATCGATCCCGCCAACGGGCGCTTCCTGCCGTGGTGGTTCCGC
AACGACGACGGCACCCTGGGCCTGGACAAACTGGTGGACGTCGACGACCAGAAAGTCCTGTCCACCGGCGTGCGCGCCAG
CGAGTACTACCTGTGCTCGAAAGAAACCAAAAAGTCCTGCGTGATCGATCCCGCCCCGTACAAGGTCGGCGACAAGATCG
TCATGCTCGCCTCCTTTATTGAACCGATCATGCTCAACGGCGCCTTCCAGGGCATCGTCGGCGCCGACCTGTCGGTGAAC
TTCATCCAGGAAATGCTCCTGGGCGCTAACCAAAAGCTGTACAGCGGCGCCGGGCAAATGGCCCTGATCGGCAGCAACGG
CCGGATCGTCGCCTATACCAAGGACCCGGGCAAATTCGGCGAGAAGGTCAGCGACATTCTCGACGCCCAACAGATTGCCA
ACATGGCCAATCTCAAGCGCGGCGAAGTGACTTACACCGTCAATAAAGAGCAAGGCCGGATCGAGTTGTATCTGCCGTTC
GGCATCGGCCAGACCGACGCGCGCTGGACACTGATGCTGCAACTGCCGCTAGACGCGGTGATGGCTGATCTGCAAAAGCT
GCAAGGCGACCTCGATGCCCAGCGCAAATCCGACACCTTCGGCATGGCCATGGTCGGCCTGATCATCGCCGGCCTCGGCC
TGCTGGTGATCTGGCTGGTGGGCCACGGCATCGCCCGTCCGCTGAAGCAAATGGTGACCATGCTCGATGACATCGCTCAG
GGCGAAGGTGACCTGACCCGTCGTTTGACCAGTGATCGCAAAGACGAACTCGGCTCCATCGCCAAAGGCTTCAATACCTT
CCTCGCCAAATTGCAGGGGATGATCACGCAGGTGGTGGCGTCGGTACAGAGCGTCAGCGATTCCTCGGAACACACCGCGG
ACATCGCGATCCGTACCAATATCGGCATACAGAAACAGATGGCCGAGATCGATCAGGTGGCCACCGCCGTGCAGGAAATG
ACCGCCACCGCCCAGGACGTCGCGCGCAACGCGACCCAGGCGGCACAAGCCGCCAGCCATGCCGATCAGGCCGCCAGTCA
GGGCATGCAGATCGTGCGTGACACCTCCAACTCGATTGGCGTGCTGGCCGTGGAAATCGGCAAGGCCGTGAACGTGGTGC
AGACCCTGGCCAAGGACAGCGAAAACATCAACGCGATCCTGATCGCCATTCGCGGGATCGCCGAGCAGACCAACCTGCTG
GCCCTCAACGCGGCGATTGAAGCGGCCCGCGCGGGTGAACAAGGACGCGGTTTTGCGGTGGTGGCCGATGAAGTGCGCAA
CCTGGCGCAGAAAACCCAGCAGGCCACCGAAGAAATCCAGAGCATGATTCAGCAACTGCAACAGGGTACTCGCGATGTAG
TGCGGGTCATGGAAGACAGCCAGAACCGCACCGACGAAAGCGTGCAACACGCGGCCAAGGCAGCCGAAGCGCTGGAAACC
ATCACCCAGGCAGTGTCGGTGATCAACGACATGAACACCCAGATCGCCAGTGCTGCCGAAGAACAGAGCGCGGTGGCCGA
CGACATCAACCGCAACGTGATCAATATCGGTCAGGTGGCCAATGAAGTGGCGGGTGGTGCGGATGAGTCGAGTTCGGCGA
GTGCGGATCTGACCAAACTGGCGGAGCAGCAGCGGCGGTTGATCAATCAGTTCAAGGTGTAA

Upstream 100 bases:

>100_bases
CATTTGCGACATTGCGCTGCAATTACTCTCTCTATACCTCATGGCTCAATAGTGGCTGCCGATACAACAGCGCAGACGTC
CTCTCGCGTGCGGAGCTCCC

Downstream 100 bases:

>100_bases
AGACGCCGGAAGGTCCTTCGGACCTTATCGCGAGCAGCGACACATCAGGCCGGAGTCAGACACTCCGGCCCGTTGAGTTT
CGGATCATTGACCAGATTCG

Product: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 713; Mature: 713

Protein sequence:

>713_residues
MKFKSIQFSVAALAGAIVLSVVAALVLYALFSGARTQEMVQQRTQAQFEQVIEQRLTSLAQTQVSQIQRELEAPLLIAGG
LVRVNALLGTPGADGQPRLNVSREQLISLIKENVEKNPKILGTYIGWEKNALDHNDAAYVGTQVVGIDPANGRFLPWWFR
NDDGTLGLDKLVDVDDQKVLSTGVRASEYYLCSKETKKSCVIDPAPYKVGDKIVMLASFIEPIMLNGAFQGIVGADLSVN
FIQEMLLGANQKLYSGAGQMALIGSNGRIVAYTKDPGKFGEKVSDILDAQQIANMANLKRGEVTYTVNKEQGRIELYLPF
GIGQTDARWTLMLQLPLDAVMADLQKLQGDLDAQRKSDTFGMAMVGLIIAGLGLLVIWLVGHGIARPLKQMVTMLDDIAQ
GEGDLTRRLTSDRKDELGSIAKGFNTFLAKLQGMITQVVASVQSVSDSSEHTADIAIRTNIGIQKQMAEIDQVATAVQEM
TATAQDVARNATQAAQAASHADQAASQGMQIVRDTSNSIGVLAVEIGKAVNVVQTLAKDSENINAILIAIRGIAEQTNLL
ALNAAIEAARAGEQGRGFAVVADEVRNLAQKTQQATEEIQSMIQQLQQGTRDVVRVMEDSQNRTDESVQHAAKAAEALET
ITQAVSVINDMNTQIASAAEEQSAVADDINRNVINIGQVANEVAGGADESSSASADLTKLAEQQRRLINQFKV

Sequences:

>Translated_713_residues
MKFKSIQFSVAALAGAIVLSVVAALVLYALFSGARTQEMVQQRTQAQFEQVIEQRLTSLAQTQVSQIQRELEAPLLIAGG
LVRVNALLGTPGADGQPRLNVSREQLISLIKENVEKNPKILGTYIGWEKNALDHNDAAYVGTQVVGIDPANGRFLPWWFR
NDDGTLGLDKLVDVDDQKVLSTGVRASEYYLCSKETKKSCVIDPAPYKVGDKIVMLASFIEPIMLNGAFQGIVGADLSVN
FIQEMLLGANQKLYSGAGQMALIGSNGRIVAYTKDPGKFGEKVSDILDAQQIANMANLKRGEVTYTVNKEQGRIELYLPF
GIGQTDARWTLMLQLPLDAVMADLQKLQGDLDAQRKSDTFGMAMVGLIIAGLGLLVIWLVGHGIARPLKQMVTMLDDIAQ
GEGDLTRRLTSDRKDELGSIAKGFNTFLAKLQGMITQVVASVQSVSDSSEHTADIAIRTNIGIQKQMAEIDQVATAVQEM
TATAQDVARNATQAAQAASHADQAASQGMQIVRDTSNSIGVLAVEIGKAVNVVQTLAKDSENINAILIAIRGIAEQTNLL
ALNAAIEAARAGEQGRGFAVVADEVRNLAQKTQQATEEIQSMIQQLQQGTRDVVRVMEDSQNRTDESVQHAAKAAEALET
ITQAVSVINDMNTQIASAAEEQSAVADDINRNVINIGQVANEVAGGADESSSASADLTKLAEQQRRLINQFKV
>Mature_713_residues
MKFKSIQFSVAALAGAIVLSVVAALVLYALFSGARTQEMVQQRTQAQFEQVIEQRLTSLAQTQVSQIQRELEAPLLIAGG
LVRVNALLGTPGADGQPRLNVSREQLISLIKENVEKNPKILGTYIGWEKNALDHNDAAYVGTQVVGIDPANGRFLPWWFR
NDDGTLGLDKLVDVDDQKVLSTGVRASEYYLCSKETKKSCVIDPAPYKVGDKIVMLASFIEPIMLNGAFQGIVGADLSVN
FIQEMLLGANQKLYSGAGQMALIGSNGRIVAYTKDPGKFGEKVSDILDAQQIANMANLKRGEVTYTVNKEQGRIELYLPF
GIGQTDARWTLMLQLPLDAVMADLQKLQGDLDAQRKSDTFGMAMVGLIIAGLGLLVIWLVGHGIARPLKQMVTMLDDIAQ
GEGDLTRRLTSDRKDELGSIAKGFNTFLAKLQGMITQVVASVQSVSDSSEHTADIAIRTNIGIQKQMAEIDQVATAVQEM
TATAQDVARNATQAAQAASHADQAASQGMQIVRDTSNSIGVLAVEIGKAVNVVQTLAKDSENINAILIAIRGIAEQTNLL
ALNAAIEAARAGEQGRGFAVVADEVRNLAQKTQQATEEIQSMIQQLQQGTRDVVRVMEDSQNRTDESVQHAAKAAEALET
ITQAVSVINDMNTQIASAAEEQSAVADDINRNVINIGQVANEVAGGADESSSASADLTKLAEQQRRLINQFKV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=319, Percent_Identity=33.8557993730408, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1788195, Length=300, Percent_Identity=35.3333333333333, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1788194, Length=381, Percent_Identity=30.4461942257218, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI1787690, Length=371, Percent_Identity=30.7277628032345, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI1789453, Length=297, Percent_Identity=30.3030303030303, Blast_Score=99, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 76740; Mature: 76740

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFKSIQFSVAALAGAIVLSVVAALVLYALFSGARTQEMVQQRTQAQFEQVIEQRLTSLA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QTQVSQIQRELEAPLLIAGGLVRVNALLGTPGADGQPRLNVSREQLISLIKENVEKNPKI
HHHHHHHHHHHCCCEEEECCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCE
LGTYIGWEKNALDHNDAAYVGTQVVGIDPANGRFLPWWFRNDDGTLGLDKLVDVDDQKVL
EEEECCCCCCCCCCCCCHHHCEEEEEECCCCCCEEEEEEECCCCCCCHHHHCCCCHHHHH
STGVRASEYYLCSKETKKSCVIDPAPYKVGDKIVMLASFIEPIMLNGAFQGIVGADLSVN
HHCCCHHHEEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCHHH
FIQEMLLGANQKLYSGAGQMALIGSNGRIVAYTKDPGKFGEKVSDILDAQQIANMANLKR
HHHHHHHCCCCHHHCCCCCEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCC
GEVTYTVNKEQGRIELYLPFGIGQTDARWTLMLQLPLDAVMADLQKLQGDLDAQRKSDTF
CCEEEEEECCCCEEEEEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHCHHHHHHCCCHH
GMAMVGLIIAGLGLLVIWLVGHGIARPLKQMVTMLDDIAQGEGDLTRRLTSDRKDELGSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHH
AKGFNTFLAKLQGMITQVVASVQSVSDSSEHTADIAIRTNIGIQKQMAEIDQVATAVQEM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHH
TATAQDVARNATQAAQAASHADQAASQGMQIVRDTSNSIGVLAVEIGKAVNVVQTLAKDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCC
ENINAILIAIRGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAQKTQQATEEIQ
CCCCEEEEEEHHHHHHCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
SMIQQLQQGTRDVVRVMEDSQNRTDESVQHAAKAAEALETITQAVSVINDMNTQIASAAE
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQSAVADDINRNVINIGQVANEVAGGADESSSASADLTKLAEQQRRLINQFKV
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFKSIQFSVAALAGAIVLSVVAALVLYALFSGARTQEMVQQRTQAQFEQVIEQRLTSLA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QTQVSQIQRELEAPLLIAGGLVRVNALLGTPGADGQPRLNVSREQLISLIKENVEKNPKI
HHHHHHHHHHHCCCEEEECCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCE
LGTYIGWEKNALDHNDAAYVGTQVVGIDPANGRFLPWWFRNDDGTLGLDKLVDVDDQKVL
EEEECCCCCCCCCCCCCHHHCEEEEEECCCCCCEEEEEEECCCCCCCHHHHCCCCHHHHH
STGVRASEYYLCSKETKKSCVIDPAPYKVGDKIVMLASFIEPIMLNGAFQGIVGADLSVN
HHCCCHHHEEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCHHH
FIQEMLLGANQKLYSGAGQMALIGSNGRIVAYTKDPGKFGEKVSDILDAQQIANMANLKR
HHHHHHHCCCCHHHCCCCCEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCC
GEVTYTVNKEQGRIELYLPFGIGQTDARWTLMLQLPLDAVMADLQKLQGDLDAQRKSDTF
CCEEEEEECCCCEEEEEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHCHHHHHHCCCHH
GMAMVGLIIAGLGLLVIWLVGHGIARPLKQMVTMLDDIAQGEGDLTRRLTSDRKDELGSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHH
AKGFNTFLAKLQGMITQVVASVQSVSDSSEHTADIAIRTNIGIQKQMAEIDQVATAVQEM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHH
TATAQDVARNATQAAQAASHADQAASQGMQIVRDTSNSIGVLAVEIGKAVNVVQTLAKDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCC
ENINAILIAIRGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAQKTQQATEEIQ
CCCCEEEEEEHHHHHHCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
SMIQQLQQGTRDVVRVMEDSQNRTDESVQHAAKAAEALETITQAVSVINDMNTQIASAAE
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQSAVADDINRNVINIGQVANEVAGGADESSSASADLTKLAEQQRRLINQFKV
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]