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The map label for this gene is rhtC [H]

Identifier: 77460931

GI number: 77460931

Start: 5318913

End: 5319542

Strand: Reverse

Name: rhtC [H]

Synonym: Pfl01_4710

Alternate gene names: 77460931

Gene position: 5319542-5318913 (Counterclockwise)

Preceding gene: 77460935

Following gene: 77460930

Centisome position: 82.62

GC content: 62.22

Gene sequence:

>630_bases
ATGTACTGGACCGAATTCTTGACCGTTGCCCTGATCCACCTGCTGGCCGTCGCCAGCCCCGGTCCTGATTTCGCCGTGGT
GGTGCGCGAAAGCGTGACCCATGGTCGACGCGCCGGGACCTGGACCGCGTTGGGCGTGGGCACGGCGATTTTCCTGCACG
TGGGTTATTCGCTGCTAGGGATCGGGCTGATCGTTTCCCAATCGATCGTGTTGTTCAACGCCCTTAAATGGGCCGCCGCC
GCTTATCTGCTGTACATCGGCTTCAAGGCCCTGCGCGCGCAACCGGCGAAAACCGTCACCGATGATCTGCACAAAGAGGT
CGGCGAACGCACCGCTCGTGGCGCGTTCACCTCGGGTTTCGTGACCAACGGCCTGAACCCGAAAGCCACGCTGTTCTTCC
TGTCGCTGTTCACCGTGGTGATCAACCCGCACACCCCGCTGACAGTCCAGGCTGGTTACGGGATCTATCTGGCTGTCGCG
ACCGCGACCTGGTTCTGCCTGGTGGCCATGTTGTTCAGCCAGCAGCGCGTGCGCGCCGGTTTCGCCCGTATGGGCCACTG
GTTCGACCGCACCATGGGCGCTGTACTGATCGCGATTGGCGTGAAACTCGCGTTCACCGAGATGCACTGA

Upstream 100 bases:

>100_bases
GTTCGTCATCAACTGTACCTGTTGTGCTTTGAAGGGAAGGCGTAATCTGCCGAGCCTACCAGATGAAACAACTCGTTACG
CTTGGCCGAAAGGAGCCCCC

Downstream 100 bases:

>100_bases
TCCTTCTGCGCTGTCATCTGTTTCGGCAAATGCTGGCGCAAAGCTAGCATTTGTACGGCTCTGCAAATCATTCCTTTGGC
TGATTTGGCTGACGTATAAG

Product: lysine exporter protein LysE/YggA

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MYWTEFLTVALIHLLAVASPGPDFAVVVRESVTHGRRAGTWTALGVGTAIFLHVGYSLLGIGLIVSQSIVLFNALKWAAA
AYLLYIGFKALRAQPAKTVTDDLHKEVGERTARGAFTSGFVTNGLNPKATLFFLSLFTVVINPHTPLTVQAGYGIYLAVA
TATWFCLVAMLFSQQRVRAGFARMGHWFDRTMGAVLIAIGVKLAFTEMH

Sequences:

>Translated_209_residues
MYWTEFLTVALIHLLAVASPGPDFAVVVRESVTHGRRAGTWTALGVGTAIFLHVGYSLLGIGLIVSQSIVLFNALKWAAA
AYLLYIGFKALRAQPAKTVTDDLHKEVGERTARGAFTSGFVTNGLNPKATLFFLSLFTVVINPHTPLTVQAGYGIYLAVA
TATWFCLVAMLFSQQRVRAGFARMGHWFDRTMGAVLIAIGVKLAFTEMH
>Mature_209_residues
MYWTEFLTVALIHLLAVASPGPDFAVVVRESVTHGRRAGTWTALGVGTAIFLHVGYSLLGIGLIVSQSIVLFNALKWAAA
AYLLYIGFKALRAQPAKTVTDDLHKEVGERTARGAFTSGFVTNGLNPKATLFFLSLFTVVINPHTPLTVQAGYGIYLAVA
TATWFCLVAMLFSQQRVRAGFARMGHWFDRTMGAVLIAIGVKLAFTEMH

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=202, Percent_Identity=30.6930693069307, Blast_Score=110, Evalue=5e-26,
Organism=Escherichia coli, GI1786522, Length=202, Percent_Identity=30.1980198019802, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI48994979, Length=149, Percent_Identity=30.8724832214765, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788099, Length=215, Percent_Identity=27.906976744186, Blast_Score=67, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22706; Mature: 22706

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYWTEFLTVALIHLLAVASPGPDFAVVVRESVTHGRRAGTWTALGVGTAIFLHVGYSLLG
CCHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
IGLIVSQSIVLFNALKWAAAAYLLYIGFKALRAQPAKTVTDDLHKEVGERTARGAFTSGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHCCC
VTNGLNPKATLFFLSLFTVVINPHTPLTVQAGYGIYLAVATATWFCLVAMLFSQQRVRAG
CCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
FARMGHWFDRTMGAVLIAIGVKLAFTEMH
HHHHHHHHHHHHHHHHHHHHHHHEEECCC
>Mature Secondary Structure
MYWTEFLTVALIHLLAVASPGPDFAVVVRESVTHGRRAGTWTALGVGTAIFLHVGYSLLG
CCHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
IGLIVSQSIVLFNALKWAAAAYLLYIGFKALRAQPAKTVTDDLHKEVGERTARGAFTSGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHCCC
VTNGLNPKATLFFLSLFTVVINPHTPLTVQAGYGIYLAVATATWFCLVAMLFSQQRVRAG
CCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
FARMGHWFDRTMGAVLIAIGVKLAFTEMH
HHHHHHHHHHHHHHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]