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The map label for this gene is tas [H]

Identifier: 77460916

GI number: 77460916

Start: 5296657

End: 5297697

Strand: Direct

Name: tas [H]

Synonym: Pfl01_4695

Alternate gene names: 77460916

Gene position: 5296657-5297697 (Clockwise)

Preceding gene: 77460908

Following gene: 77460918

Centisome position: 82.27

GC content: 60.81

Gene sequence:

>1041_bases
ATGGACTATCGCCAGCTAGGCCGTACCGACCTGAACGTGAGTGCAATCTGCCTCGGCACCATGACCTGGGGCGAGCAAAA
CACTGAAGCTGAAGCCTTCGCCCAGATCGAACGGGCAAAAGAGGCCGGGATCAATTTCCTCGACACTGCCGAAATGTACC
CGGTGCCGCCAAAAGCCGACACCTACGCCACCACCGAGCGCTACATCGGCAATTACTTCAAGAGCCGTGGCGACCGCGCC
GACTGGATTCTCGCCAGCAAGATCGCCGGCCCCGGCAACACCATCGACTACATCCGCGACAAGAACCTGCGCCACAACCG
CCAGCACATCACCGAGGCCGTGGACGCCAGCCTCAAGCGCCTGCAGACCGACTACATCGACCTCTACCAGTTGCACTGGC
CGGAGCGCAGCACCAACTTTTTCGGACAGCTGGGCTACAAGCACCAGACCGAAGCCAACCTGACGCCGCTCGAAGACACC
CTTGAGGCGCTCGATGAGCAAGTGAAGGCCGGCAAGATCCGCCACATCGGTTTGTCCAACGAAACGCCGTGGGGCACCAT
GCGATTTCTCGCCCTGGCCGAAGCCCGTGGCTGGCCGCGCGCTGTCTCGATCCAGAACCCGTACAACCTGCTCAACCGCA
GTTTCGAGATCGGTCTGGCGGAAATCGCCATCCGTGAACAATGCGGCCTGCTCGCCTATTCGCCGCTGGCGTTCGGTTTC
CTGTCGGGCAAGTACGAAGGTGGGGCGCGTCCACCGAAAGGCCGCCTGAGCCTCTACAGCCGTTTCAGCCGCTATTTCAA
CCCGCAATCGGAAGCAGCATGCAGCCGTTACGTGGCGCTGGCCCGTGAACACGGCCTGGATCCGGCACAAATGGCCCTGG
CCTTTGTGAATCAGCAACCGTTCGTCACCAGCAACATCATCGGGGCGACGACGCTGGAACAGCTGGACAGCAACATTGCG
AGCTACGAGCTGAAACTGTCGAAGGAAGTGCTGGAAGGGATCGAAGCGATTCACAAGGATTATCCGAACCCGGCGCCGTG
A

Upstream 100 bases:

>100_bases
GCGGGGCATCACTTCCACTGCAGAAAGAGGTCGGCAATTATGCAGATTGCGAAAAAAATTTCAACCTGCTTTTATGCTTG
TTTTGCCCAAGGAGCACCCG

Downstream 100 bases:

>100_bases
TCAGCCGCTAAAAGCTTCGCGACCAGGCTCGCTCCCACAGGTACAGCGTGATGATTGTGGGAGCGAGCCTGCTCGCGAAG
GGGCCAGTCAACTCACTGCA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MDYRQLGRTDLNVSAICLGTMTWGEQNTEAEAFAQIERAKEAGINFLDTAEMYPVPPKADTYATTERYIGNYFKSRGDRA
DWILASKIAGPGNTIDYIRDKNLRHNRQHITEAVDASLKRLQTDYIDLYQLHWPERSTNFFGQLGYKHQTEANLTPLEDT
LEALDEQVKAGKIRHIGLSNETPWGTMRFLALAEARGWPRAVSIQNPYNLLNRSFEIGLAEIAIREQCGLLAYSPLAFGF
LSGKYEGGARPPKGRLSLYSRFSRYFNPQSEAACSRYVALAREHGLDPAQMALAFVNQQPFVTSNIIGATTLEQLDSNIA
SYELKLSKEVLEGIEAIHKDYPNPAP

Sequences:

>Translated_346_residues
MDYRQLGRTDLNVSAICLGTMTWGEQNTEAEAFAQIERAKEAGINFLDTAEMYPVPPKADTYATTERYIGNYFKSRGDRA
DWILASKIAGPGNTIDYIRDKNLRHNRQHITEAVDASLKRLQTDYIDLYQLHWPERSTNFFGQLGYKHQTEANLTPLEDT
LEALDEQVKAGKIRHIGLSNETPWGTMRFLALAEARGWPRAVSIQNPYNLLNRSFEIGLAEIAIREQCGLLAYSPLAFGF
LSGKYEGGARPPKGRLSLYSRFSRYFNPQSEAACSRYVALAREHGLDPAQMALAFVNQQPFVTSNIIGATTLEQLDSNIA
SYELKLSKEVLEGIEAIHKDYPNPAP
>Mature_346_residues
MDYRQLGRTDLNVSAICLGTMTWGEQNTEAEAFAQIERAKEAGINFLDTAEMYPVPPKADTYATTERYIGNYFKSRGDRA
DWILASKIAGPGNTIDYIRDKNLRHNRQHITEAVDASLKRLQTDYIDLYQLHWPERSTNFFGQLGYKHQTEANLTPLEDT
LEALDEQVKAGKIRHIGLSNETPWGTMRFLALAEARGWPRAVSIQNPYNLLNRSFEIGLAEIAIREQCGLLAYSPLAFGF
LSGKYEGGARPPKGRLSLYSRFSRYFNPQSEAACSRYVALAREHGLDPAQMALAFVNQQPFVTSNIIGATTLEQLDSNIA
SYELKLSKEVLEGIEAIHKDYPNPAP

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=353, Percent_Identity=28.328611898017, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI4504825, Length=351, Percent_Identity=28.2051282051282, Blast_Score=118, Evalue=7e-27,
Organism=Homo sapiens, GI27436964, Length=355, Percent_Identity=27.0422535211268, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI27436962, Length=353, Percent_Identity=26.628895184136, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI27436966, Length=355, Percent_Identity=26.7605633802817, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI27436971, Length=358, Percent_Identity=25.9776536312849, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI41152114, Length=234, Percent_Identity=28.2051282051282, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI41327764, Length=331, Percent_Identity=27.4924471299094, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI223718702, Length=343, Percent_Identity=26.530612244898, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1789199, Length=346, Percent_Identity=54.3352601156069, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI87081735, Length=351, Percent_Identity=31.0541310541311, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1789375, Length=334, Percent_Identity=29.3413173652695, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788070, Length=340, Percent_Identity=27.9411764705882, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1788081, Length=336, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325169, Length=358, Percent_Identity=25.4189944134078, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6319958, Length=320, Percent_Identity=26.25, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6323998, Length=348, Percent_Identity=25.2873563218391, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319951, Length=345, Percent_Identity=23.4782608695652, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322615, Length=268, Percent_Identity=23.5074626865672, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24646159, Length=187, Percent_Identity=29.9465240641711, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 38904; Mature: 38904

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYRQLGRTDLNVSAICLGTMTWGEQNTEAEAFAQIERAKEAGINFLDTAEMYPVPPKAD
CCHHHHCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCC
TYATTERYIGNYFKSRGDRADWILASKIAGPGNTIDYIRDKNLRHNRQHITEAVDASLKR
CHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHH
LQTDYIDLYQLHWPERSTNFFGQLGYKHQTEANLTPLEDTLEALDEQVKAGKIRHIGLSN
HHHHHHHHHHEECCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCC
ETPWGTMRFLALAEARGWPRAVSIQNPYNLLNRSFEIGLAEIAIREQCGLLAYSPLAFGF
CCCCHHHHHHHHHHCCCCCCEEECCCHHHHHCCCHHHHHHHHHHHHHCCCEEECHHHHHH
LSGKYEGGARPPKGRLSLYSRFSRYFNPQSEAACSRYVALAREHGLDPAQMALAFVNQQP
HCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCC
FVTSNIIGATTLEQLDSNIASYELKLSKEVLEGIEAIHKDYPNPAP
CCHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDYRQLGRTDLNVSAICLGTMTWGEQNTEAEAFAQIERAKEAGINFLDTAEMYPVPPKAD
CCHHHHCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCC
TYATTERYIGNYFKSRGDRADWILASKIAGPGNTIDYIRDKNLRHNRQHITEAVDASLKR
CHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHH
LQTDYIDLYQLHWPERSTNFFGQLGYKHQTEANLTPLEDTLEALDEQVKAGKIRHIGLSN
HHHHHHHHHHEECCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCC
ETPWGTMRFLALAEARGWPRAVSIQNPYNLLNRSFEIGLAEIAIREQCGLLAYSPLAFGF
CCCCHHHHHHHHHHCCCCCCEEECCCHHHHHCCCHHHHHHHHHHHHHCCCEEECHHHHHH
LSGKYEGGARPPKGRLSLYSRFSRYFNPQSEAACSRYVALAREHGLDPAQMALAFVNQQP
HCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCC
FVTSNIIGATTLEQLDSNIASYELKLSKEVLEGIEAIHKDYPNPAP
CCHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]