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The map label for this gene is mdtA [H]

Identifier: 77460882

GI number: 77460882

Start: 5258469

End: 5259629

Strand: Direct

Name: mdtA [H]

Synonym: Pfl01_4661

Alternate gene names: 77460882

Gene position: 5258469-5259629 (Clockwise)

Preceding gene: 77460878

Following gene: 77460883

Centisome position: 81.67

GC content: 62.7

Gene sequence:

>1161_bases
ATGCAAATCCAGAAGAAAAAGGCCCTGCTCGCCACCCTGCTGATCGCCCTCGCAGCCGCCGGTCTGTGGTACGCATACAA
ACCCGCCCCGGCCAAACTCGCCGGCCCCACCGCCATCCCGGTGCGAGTCGTCGCCGTCAGCGAAAAAGACGTCCCCCGCT
ACACCAGCGGCATCGGCTCGGTCCTCTCGTTGCACAGCGTCGTGGTGCGCCCACAGATCGACGGCATCCTCACCAAGCTC
TTGGTCAAAGAGGGTCAGCTGGTGAAACAGGGCGACCTGCTCGCCACCATCGACGACCGCTCGATCCGCGCCAGCCTCGA
CCAGGCCCGGGCGCAACTGGGCGAAAGCCAGGCGCAACTGCAAGTCGCTTTGGTCAACCTCAAGCGCTACAAACTGCTCA
GCGTCGACGACGGTGTATCGAAGCAGACCTACGACCAGCAGCAGGCACTGGTCAACCAGCTCAAAGCCACCGCCCAGGGC
AATCAGGCCGCGATTGACGCGGCACAGGTACAACTTTCCTACACCCAGATTCGTTCCCCGGTCACCGGCCGCGTCGGGAT
TCGCACGGTCGACGAAGGCAACTTCCTGCGCATGACCGACACCCAGGGTCTGTTCACCGTGACCCAGATCGACCCGATCG
CCGTCGAGTTTTCCCTGCCCCAGCAAATGCTGCCGACCCTGCAAGGCCTGATCAGCGACCCGCAGCGCGCGCAGGTCAAG
GCCTACATCGGCGCCGACACCGATGGCGAAACCGGCAACCTGCTCGGCGAAGGTCACCTGACCCTGATCGACAACCAGAT
CAACGCCAACACCGGCACCATCCGCGCCAAGGCTGAGTTCGACAATCCCAACCAGAAGCTCTGGCCCGGCCTGCTGGTGA
CGGTAAAGATTCAGACAGCGCTGGATAAAGATGCACTGGTGGTCCCGCCCACTGTCGTACAACGCGGACTCGATCAGCAC
TTCGTGTACCGGGTCAACGGCGACAAGGTTGAAGCGGTGCAGGTGCAAATGGTTTATCAGGGCAGCGGTCAGGACATCAT
CAAAGGCGTGAAACCCGGCGACGTATTGGTCAGTGACGGCCAGTCGCGGCTCAAGCCCGGTTCGACCGTGCAGGTCATGA
GCGAACCGCCGCAGGTGGTGCAAGCGGAGCCCAAGCCATGA

Upstream 100 bases:

>100_bases
AACTGACAGCGCCGTCAGCCAGCCGTCACCCTCCTGACCCCCAAACAAGTTTATAAAGAACCAACCTGCCCAAACCCCGT
CCCCCTGGCGCCCCACAAGC

Downstream 100 bases:

>100_bases
AGCAGCACAAAGGCGTTTCGACCTGGTGCATCGATCACCCGGTGGCGACGATTCTGCTGACCATCGCGCTGGTGCTGGTC
GGGGTGATTGCCTTCCCGCG

Product: secretion protein HlyD

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MQIQKKKALLATLLIALAAAGLWYAYKPAPAKLAGPTAIPVRVVAVSEKDVPRYTSGIGSVLSLHSVVVRPQIDGILTKL
LVKEGQLVKQGDLLATIDDRSIRASLDQARAQLGESQAQLQVALVNLKRYKLLSVDDGVSKQTYDQQQALVNQLKATAQG
NQAAIDAAQVQLSYTQIRSPVTGRVGIRTVDEGNFLRMTDTQGLFTVTQIDPIAVEFSLPQQMLPTLQGLISDPQRAQVK
AYIGADTDGETGNLLGEGHLTLIDNQINANTGTIRAKAEFDNPNQKLWPGLLVTVKIQTALDKDALVVPPTVVQRGLDQH
FVYRVNGDKVEAVQVQMVYQGSGQDIIKGVKPGDVLVSDGQSRLKPGSTVQVMSEPPQVVQAEPKP

Sequences:

>Translated_386_residues
MQIQKKKALLATLLIALAAAGLWYAYKPAPAKLAGPTAIPVRVVAVSEKDVPRYTSGIGSVLSLHSVVVRPQIDGILTKL
LVKEGQLVKQGDLLATIDDRSIRASLDQARAQLGESQAQLQVALVNLKRYKLLSVDDGVSKQTYDQQQALVNQLKATAQG
NQAAIDAAQVQLSYTQIRSPVTGRVGIRTVDEGNFLRMTDTQGLFTVTQIDPIAVEFSLPQQMLPTLQGLISDPQRAQVK
AYIGADTDGETGNLLGEGHLTLIDNQINANTGTIRAKAEFDNPNQKLWPGLLVTVKIQTALDKDALVVPPTVVQRGLDQH
FVYRVNGDKVEAVQVQMVYQGSGQDIIKGVKPGDVLVSDGQSRLKPGSTVQVMSEPPQVVQAEPKP
>Mature_386_residues
MQIQKKKALLATLLIALAAAGLWYAYKPAPAKLAGPTAIPVRVVAVSEKDVPRYTSGIGSVLSLHSVVVRPQIDGILTKL
LVKEGQLVKQGDLLATIDDRSIRASLDQARAQLGESQAQLQVALVNLKRYKLLSVDDGVSKQTYDQQQALVNQLKATAQG
NQAAIDAAQVQLSYTQIRSPVTGRVGIRTVDEGNFLRMTDTQGLFTVTQIDPIAVEFSLPQQMLPTLQGLISDPQRAQVK
AYIGADTDGETGNLLGEGHLTLIDNQINANTGTIRAKAEFDNPNQKLWPGLLVTVKIQTALDKDALVVPPTVVQRGLDQH
FVYRVNGDKVEAVQVQMVYQGSGQDIIKGVKPGDVLVSDGQSRLKPGSTVQVMSEPPQVVQAEPKP

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=342, Percent_Identity=38.0116959064327, Blast_Score=214, Evalue=9e-57,
Organism=Escherichia coli, GI1789665, Length=314, Percent_Identity=30.5732484076433, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1789929, Length=391, Percent_Identity=26.3427109974425, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786668, Length=310, Percent_Identity=31.9354838709677, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI87081951, Length=196, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87081796, Length=391, Percent_Identity=25.0639386189258, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41584; Mature: 41584

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIQKKKALLATLLIALAAAGLWYAYKPAPAKLAGPTAIPVRVVAVSEKDVPRYTSGIGS
CCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHH
VLSLHSVVVRPQIDGILTKLLVKEGQLVKQGDLLATIDDRSIRASLDQARAQLGESQAQL
HHHHHHHEECCCHHHHHHHHHHHCCCEEECCCEEEEECCCHHHHHHHHHHHHHCCCHHHE
QVALVNLKRYKLLSVDDGVSKQTYDQQQALVNQLKATAQGNQAAIDAAQVQLSYTQIRSP
EEEEEEHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHEEEHHHEEEEHHHHCCC
VTGRVGIRTVDEGNFLRMTDTQGLFTVTQIDPIAVEFSLPQQMLPTLQGLISDPQRAQVK
CCCCCEEEEECCCCEEEEECCCCEEEEEECCCEEEEECCCHHHHHHHHHHHCCCCCCEEE
AYIGADTDGETGNLLGEGHLTLIDNQINANTGTIRAKAEFDNPNQKLWPGLLVTVKIQTA
EEECCCCCCCCCCEEECCCEEEEECEECCCCCEEEEEEECCCCCCEECCCEEEEEEEEEC
LDKDALVVPPTVVQRGLDQHFVYRVNGDKVEAVQVQMVYQGSGQDIIKGVKPGDVLVSDG
CCCCCEEECHHHHHCCCCCEEEEEECCCEEEEEEEEEEEECCCHHHHCCCCCCCEEEECC
QSRLKPGSTVQVMSEPPQVVQAEPKP
HHHCCCCCEEEEECCCCHHEECCCCC
>Mature Secondary Structure
MQIQKKKALLATLLIALAAAGLWYAYKPAPAKLAGPTAIPVRVVAVSEKDVPRYTSGIGS
CCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHH
VLSLHSVVVRPQIDGILTKLLVKEGQLVKQGDLLATIDDRSIRASLDQARAQLGESQAQL
HHHHHHHEECCCHHHHHHHHHHHCCCEEECCCEEEEECCCHHHHHHHHHHHHHCCCHHHE
QVALVNLKRYKLLSVDDGVSKQTYDQQQALVNQLKATAQGNQAAIDAAQVQLSYTQIRSP
EEEEEEHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHEEEHHHEEEEHHHHCCC
VTGRVGIRTVDEGNFLRMTDTQGLFTVTQIDPIAVEFSLPQQMLPTLQGLISDPQRAQVK
CCCCCEEEEECCCCEEEEECCCCEEEEEECCCEEEEECCCHHHHHHHHHHHCCCCCCEEE
AYIGADTDGETGNLLGEGHLTLIDNQINANTGTIRAKAEFDNPNQKLWPGLLVTVKIQTA
EEECCCCCCCCCCEEECCCEEEEECEECCCCCEEEEEEECCCCCCEECCCEEEEEEEEEC
LDKDALVVPPTVVQRGLDQHFVYRVNGDKVEAVQVQMVYQGSGQDIIKGVKPGDVLVSDG
CCCCCEEECHHHHHCCCCCEEEEEECCCEEEEEEEEEEEECCCHHHHCCCCCCCEEEECC
QSRLKPGSTVQVMSEPPQVVQAEPKP
HHHCCCCCEEEEECCCCHHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA