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The map label for this gene is argD2 [H]

Identifier: 77460857

GI number: 77460857

Start: 5234753

End: 5235940

Strand: Reverse

Name: argD2 [H]

Synonym: Pfl01_4636

Alternate gene names: 77460857

Gene position: 5235940-5234753 (Counterclockwise)

Preceding gene: 77460864

Following gene: 77460852

Centisome position: 81.32

GC content: 63.64

Gene sequence:

>1188_bases
ATGACCGCCGCCCTGATGAACACCTATCAACCGCTGGACTTGAGCTTCATCAAAGGCCTGGGCACCCGACTCTGGGATCT
GTCGGGCCGCGAGTATCTGGACGCGGTGGCGGGCGTGGCGGTGACCAATGTCGGCCACTCGCACCCACGCATCGTGTCGG
CGATCAGCGAGCAGGCGGGATTGCTGCTGCACACCTCCAACCTCTACAGCATCGACTGGCAACAGTCGCTGGCGCGGAAG
CTGACGCAGCTGGCGGGGATGGAGCGGGCGTTCTTCAACAACTCCGGTGCCGAGGCCAATGAAACCGCGCTAAAACTGGC
GCGTCTGTACGGCTGGCACAAAGGCATCGAGCAGCCGCTGGTGGTGGTGATGGCCAACGCGTTTCATGGCCGTACCCTTG
GCACCTTGTCCGCCAGCGATGGCCCGGCGGTGCGCCTGGGTTTCAATGAGTTGCCCGGGGATTTTGTCAAGGTGCCGTTC
GGCGATCTTGAGGCGCTGGAGCAAGTGCAGCGCAAGCATGGCCAGCGGATCGTGGCGATTCTGGTCGAGCCGATCCAGGG
TGAAAGCGGCGTGCAACTGGCGCCTCCCGGCTACCTCAAGGCCCTGCGTGAATTGTGCAACCGCCACGCCTGGCTGTTGA
TGCTCGACGAAATTCAGACCGGCATCGGTCGCACCGGTCGCTGGTTCGCGTTTCAGCACGAAGGCATCGTTCCCGACGTC
ATGACCCTCGCCAAGGGCCTGGGTAATGGCGTGCCGATCGGTGCCTGCCTGGCACGGGGCCGGGCGGCCGATCTGTTCAC
CCCCGGCAGCCATGGCAGCACCTTCGGCGGTAATCCACTGGCGTGCCGGGTGGGTTGCACCGTGCTCGAGATCATCGAAG
AACAGGGCCTGCTGGAAAATGCCAGGGTCCAGGGCGAGCGCCTGCTGACCCGCCTGCGTGCAGAGCTGGCGGACAATCCG
AATGTGCTGGCGATTCGTGGGCAAGGGCTGATGATCGGCATCGAACTCAAGCAGCCGATCCGCGACCTGACACTGATTGC
GGCACGGGATCATGGACTGCTGATCAACGTCACGCGCGGCAAGACGATCCGGCTGCTGCCGCCGCTGACGATTGATGAGC
GGGAGGTGGGGATGATTGTCAGAGGTGTTGGCCGTTCCCTGAGCCATGTCTCATCCCTCGGTCAGTAG

Upstream 100 bases:

>100_bases
TCAAGCCCGGCTTTTAAATGATTGAAGTTTTGCCGAGTTTATCCAGTTCAGGTGGATAACCATACTGCCAGCACCTCTCA
CCTCGCTGGAGTTTGCCGAC

Downstream 100 bases:

>100_bases
TGAAATCTGCAAGTTATGACGCAGATTTCGCCGTCTACGATCGCATAGACCAAGCGATGCTCGGCAGTTATCCGCCGTGA
CCAGAAGCCGCTCATGTTGT

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT 2 [H]

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MTAALMNTYQPLDLSFIKGLGTRLWDLSGREYLDAVAGVAVTNVGHSHPRIVSAISEQAGLLLHTSNLYSIDWQQSLARK
LTQLAGMERAFFNNSGAEANETALKLARLYGWHKGIEQPLVVVMANAFHGRTLGTLSASDGPAVRLGFNELPGDFVKVPF
GDLEALEQVQRKHGQRIVAILVEPIQGESGVQLAPPGYLKALRELCNRHAWLLMLDEIQTGIGRTGRWFAFQHEGIVPDV
MTLAKGLGNGVPIGACLARGRAADLFTPGSHGSTFGGNPLACRVGCTVLEIIEEQGLLENARVQGERLLTRLRAELADNP
NVLAIRGQGLMIGIELKQPIRDLTLIAARDHGLLINVTRGKTIRLLPPLTIDEREVGMIVRGVGRSLSHVSSLGQ

Sequences:

>Translated_395_residues
MTAALMNTYQPLDLSFIKGLGTRLWDLSGREYLDAVAGVAVTNVGHSHPRIVSAISEQAGLLLHTSNLYSIDWQQSLARK
LTQLAGMERAFFNNSGAEANETALKLARLYGWHKGIEQPLVVVMANAFHGRTLGTLSASDGPAVRLGFNELPGDFVKVPF
GDLEALEQVQRKHGQRIVAILVEPIQGESGVQLAPPGYLKALRELCNRHAWLLMLDEIQTGIGRTGRWFAFQHEGIVPDV
MTLAKGLGNGVPIGACLARGRAADLFTPGSHGSTFGGNPLACRVGCTVLEIIEEQGLLENARVQGERLLTRLRAELADNP
NVLAIRGQGLMIGIELKQPIRDLTLIAARDHGLLINVTRGKTIRLLPPLTIDEREVGMIVRGVGRSLSHVSSLGQ
>Mature_394_residues
TAALMNTYQPLDLSFIKGLGTRLWDLSGREYLDAVAGVAVTNVGHSHPRIVSAISEQAGLLLHTSNLYSIDWQQSLARKL
TQLAGMERAFFNNSGAEANETALKLARLYGWHKGIEQPLVVVMANAFHGRTLGTLSASDGPAVRLGFNELPGDFVKVPFG
DLEALEQVQRKHGQRIVAILVEPIQGESGVQLAPPGYLKALRELCNRHAWLLMLDEIQTGIGRTGRWFAFQHEGIVPDVM
TLAKGLGNGVPIGACLARGRAADLFTPGSHGSTFGGNPLACRVGCTVLEIIEEQGLLENARVQGERLLTRLRAELADNPN
VLAIRGQGLMIGIELKQPIRDLTLIAARDHGLLINVTRGKTIRLLPPLTIDEREVGMIVRGVGRSLSHVSSLGQ

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=391, Percent_Identity=39.6419437340153, Blast_Score=268, Evalue=8e-72,
Organism=Homo sapiens, GI284507298, Length=304, Percent_Identity=42.4342105263158, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI13994255, Length=412, Percent_Identity=32.0388349514563, Blast_Score=175, Evalue=6e-44,
Organism=Homo sapiens, GI37574042, Length=402, Percent_Identity=28.1094527363184, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI24119277, Length=351, Percent_Identity=32.1937321937322, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI226442709, Length=382, Percent_Identity=27.4869109947644, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI226442705, Length=402, Percent_Identity=27.1144278606965, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI188536080, Length=417, Percent_Identity=26.378896882494, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI38679950, Length=417, Percent_Identity=26.378896882494, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI38679946, Length=417, Percent_Identity=26.378896882494, Blast_Score=116, Evalue=3e-26,
Organism=Escherichia coli, GI1789759, Length=380, Percent_Identity=41.5789473684211, Blast_Score=293, Evalue=1e-80,
Organism=Escherichia coli, GI1788044, Length=396, Percent_Identity=39.1414141414141, Blast_Score=275, Evalue=4e-75,
Organism=Escherichia coli, GI145693181, Length=385, Percent_Identity=38.1818181818182, Blast_Score=238, Evalue=4e-64,
Organism=Escherichia coli, GI1787560, Length=392, Percent_Identity=34.4387755102041, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1789016, Length=384, Percent_Identity=32.5520833333333, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1786991, Length=398, Percent_Identity=29.1457286432161, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786349, Length=308, Percent_Identity=30.1948051948052, Blast_Score=117, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI25144271, Length=375, Percent_Identity=36, Blast_Score=255, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI32564660, Length=433, Percent_Identity=34.1801385681293, Blast_Score=211, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI25144274, Length=261, Percent_Identity=37.5478927203065, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI71992977, Length=417, Percent_Identity=30.4556354916067, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71981843, Length=176, Percent_Identity=30.6818181818182, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17541228, Length=432, Percent_Identity=23.6111111111111, Blast_Score=99, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6323470, Length=406, Percent_Identity=36.9458128078818, Blast_Score=248, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6324432, Length=389, Percent_Identity=37.5321336760925, Blast_Score=243, Evalue=5e-65,
Organism=Saccharomyces cerevisiae, GI6324386, Length=316, Percent_Identity=26.5822784810127, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6321456, Length=433, Percent_Identity=24.2494226327945, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21357415, Length=385, Percent_Identity=37.9220779220779, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI28574759, Length=401, Percent_Identity=31.4214463840399, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI161085790, Length=406, Percent_Identity=31.0344827586207, Blast_Score=171, Evalue=9e-43,
Organism=Drosophila melanogaster, GI21356575, Length=426, Percent_Identity=29.3427230046948, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI281366494, Length=425, Percent_Identity=25.1764705882353, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24667139, Length=425, Percent_Identity=25.1764705882353, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24667143, Length=425, Percent_Identity=25.1764705882353, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42748; Mature: 42617

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAALMNTYQPLDLSFIKGLGTRLWDLSGREYLDAVAGVAVTNVGHSHPRIVSAISEQAG
CCCCCCCCCCCCCHHHHHHCCHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
LLLHTSNLYSIDWQQSLARKLTQLAGMERAFFNNSGAEANETALKLARLYGWHKGIEQPL
EEEEECCEEEECHHHHHHHHHHHHHCHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCE
VVVMANAFHGRTLGTLSASDGPAVRLGFNELPGDFVKVPFGDLEALEQVQRKHGQRIVAI
EEEEECCCCCCEEEEEECCCCCEEEECHHHCCCCEEECCCCHHHHHHHHHHHCCCEEEEE
LVEPIQGESGVQLAPPGYLKALRELCNRHAWLLMLDEIQTGIGRTGRWFAFQHEGIVPDV
EEECCCCCCCCEECCCHHHHHHHHHHCCCEEEEEHHHHHHCCCCCCCEEEEECCCCCHHH
MTLAKGLGNGVPIGACLARGRAADLFTPGSHGSTFGGNPLACRVGCTVLEIIEEQGLLEN
HHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCHHH
ARVQGERLLTRLRAELADNPNVLAIRGQGLMIGIELKQPIRDLTLIAARDHGLLINVTRG
HHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEECCCCHHHEEEEEECCCCEEEEEECC
KTIRLLPPLTIDEREVGMIVRGVGRSLSHVSSLGQ
CEEEECCCCCCCCHHHHHHHHHHCHHHHHHHHCCC
>Mature Secondary Structure 
TAALMNTYQPLDLSFIKGLGTRLWDLSGREYLDAVAGVAVTNVGHSHPRIVSAISEQAG
CCCCCCCCCCCCHHHHHHCCHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
LLLHTSNLYSIDWQQSLARKLTQLAGMERAFFNNSGAEANETALKLARLYGWHKGIEQPL
EEEEECCEEEECHHHHHHHHHHHHHCHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCE
VVVMANAFHGRTLGTLSASDGPAVRLGFNELPGDFVKVPFGDLEALEQVQRKHGQRIVAI
EEEEECCCCCCEEEEEECCCCCEEEECHHHCCCCEEECCCCHHHHHHHHHHHCCCEEEEE
LVEPIQGESGVQLAPPGYLKALRELCNRHAWLLMLDEIQTGIGRTGRWFAFQHEGIVPDV
EEECCCCCCCCEECCCHHHHHHHHHHCCCEEEEEHHHHHHCCCCCCCEEEEECCCCCHHH
MTLAKGLGNGVPIGACLARGRAADLFTPGSHGSTFGGNPLACRVGCTVLEIIEEQGLLEN
HHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCHHH
ARVQGERLLTRLRAELADNPNVLAIRGQGLMIGIELKQPIRDLTLIAARDHGLLINVTRG
HHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEECCCCHHHEEEEEECCCCEEEEEECC
KTIRLLPPLTIDEREVGMIVRGVGRSLSHVSSLGQ
CEEEECCCCCCCCHHHHHHHHHHCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]