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The map label for this gene is xseA [H]

Identifier: 77460813

GI number: 77460813

Start: 5191474

End: 5192853

Strand: Direct

Name: xseA [H]

Synonym: Pfl01_4592

Alternate gene names: 77460813

Gene position: 5191474-5192853 (Clockwise)

Preceding gene: 77460812

Following gene: 77460814

Centisome position: 80.63

GC content: 65.36

Gene sequence:

>1380_bases
ATGATTAAAGATCCCTTTGCAAGACTCGGCCTCGACCGCGAAGTCCTGACCGTCAGCCAGCTCAACGGCCGCGCGCGGGT
GTTGCTCGAAGACGTGTTCAGCAACATCTGGGTCGAAGGCGAAATCTCCAACCTCGCCCGCCCGGCGTCCGGCCACGTGT
ATTTCACGCTCAAGGACAGCGGCGCGCAGGTGCGTTGCGCACTGTTCCGGCAGAACGCCGCGCGGGTGCGTCAGGCGCTG
AAGGATGGCCTGGCAGTCAAGGTGCGCGGCAAGGTCTCGCTGTTCGAAGGGCGTGGCGACTATCAGCTGATCCTCGACAC
CGTGGAGCCTGCCGGCGACGGTGCGCTGCGCCTTGCTTTCGATGCCCTGAAGGAAAAGCTCAGCGCCGAAGGCCTGTTCA
GTGCCGAGCGCAAGGTGCCGCTGCCGGCCCATCCGCAGCGCATCGGCATCATCAGTTCGCCGACCGGCGCGGTGATTCGC
GACATCATCAGCGTGTTCCGCCGCCGCGCGCCGCAAGTACAACTGACGCTGATTCCCACCGCCGTTCAGGGCCGCGAAGC
CACCGCGCAGATCGTCCGCGCCCTGAAACTGGCCGATGCCCGTGGCTTCGACGCGCTGATCCTGGCCCGTGGCGGCGGCT
CGCTGGAAGACCTGTGGTGCTTCAATGAAGAGGCGGTGGCCCGGGCGGTGGATGCCTGCGTTACGCCGATCGTCAGTGCA
GTCGGGCATGAAACCGATGTGTCGATCAGCGACTTTGTGGCTGACGTGCGCGCGCCTACACCGTCCGCTGCTGCTGAACT
GCTTGCCCCGGATTCCAGCCACCTGATCCGACAGGTCGAAAGCCTGCATCGCCGGCTGGTGATGCGCATGCGTGATCGCC
TGATGCGCGATCGATTGCGCCTCGAAGGCATGACCCGCCGCTTGCGCCATCCCGGCGAACGTCTGCGCCAGCAGGCACAG
CGTCTGGATGACCTGGACATGCGCATGCGCCGCGCTTTCGAGCGCCAGCTCAATACCCGTCGCGAACGCTTGATCCGCCT
GGAAACCCGCCTCGCCGGGCAACATCCGGGACGCCAACTCGCGCTGCTGCGCCAACGCCTCGACAGCCTCGCCGAGCGCC
TGCCACGCGCCATGAACGAAGGCCTGAAACGCCGTCGCCTGCAGTTGCAAAGCCAGATGCAGACCCTGCACGTGGTCAGC
CCGCTGGCGACTCTCGGCCGTGGCTACAGCATTCTGCTGGATGAACGCGGCAACGCGATCCGCAACGCCGCGCAAACTCA
CACCGGTCAGCGCCTCAAGGCCAGACTGGGCGAAGGCGAACTGCAAGTGCGCGTCGAGGACAATCACCTGACGCCCGTCA
CTCTCTCTTTACTGGACTGA

Upstream 100 bases:

>100_bases
TGCCAAAGCACTGTCGCCCTCGCTTCTCGGCAAAATCCCACACCTCTGGTGCAACACTTCCTCCAGACATTCACCGGCGA
ATGCCTTTAAACTGCGCCCC

Downstream 100 bases:

>100_bases
TCCATGCCGCGCTTTCTCGCTCCGCTGCTGTTGCTGTGCCTGACCTTCAACGCTCACGCCGACAGTTACATCACCCGCCT
GCTGAACAAACCGGTGCCGG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MIKDPFARLGLDREVLTVSQLNGRARVLLEDVFSNIWVEGEISNLARPASGHVYFTLKDSGAQVRCALFRQNAARVRQAL
KDGLAVKVRGKVSLFEGRGDYQLILDTVEPAGDGALRLAFDALKEKLSAEGLFSAERKVPLPAHPQRIGIISSPTGAVIR
DIISVFRRRAPQVQLTLIPTAVQGREATAQIVRALKLADARGFDALILARGGGSLEDLWCFNEEAVARAVDACVTPIVSA
VGHETDVSISDFVADVRAPTPSAAAELLAPDSSHLIRQVESLHRRLVMRMRDRLMRDRLRLEGMTRRLRHPGERLRQQAQ
RLDDLDMRMRRAFERQLNTRRERLIRLETRLAGQHPGRQLALLRQRLDSLAERLPRAMNEGLKRRRLQLQSQMQTLHVVS
PLATLGRGYSILLDERGNAIRNAAQTHTGQRLKARLGEGELQVRVEDNHLTPVTLSLLD

Sequences:

>Translated_459_residues
MIKDPFARLGLDREVLTVSQLNGRARVLLEDVFSNIWVEGEISNLARPASGHVYFTLKDSGAQVRCALFRQNAARVRQAL
KDGLAVKVRGKVSLFEGRGDYQLILDTVEPAGDGALRLAFDALKEKLSAEGLFSAERKVPLPAHPQRIGIISSPTGAVIR
DIISVFRRRAPQVQLTLIPTAVQGREATAQIVRALKLADARGFDALILARGGGSLEDLWCFNEEAVARAVDACVTPIVSA
VGHETDVSISDFVADVRAPTPSAAAELLAPDSSHLIRQVESLHRRLVMRMRDRLMRDRLRLEGMTRRLRHPGERLRQQAQ
RLDDLDMRMRRAFERQLNTRRERLIRLETRLAGQHPGRQLALLRQRLDSLAERLPRAMNEGLKRRRLQLQSQMQTLHVVS
PLATLGRGYSILLDERGNAIRNAAQTHTGQRLKARLGEGELQVRVEDNHLTPVTLSLLD
>Mature_459_residues
MIKDPFARLGLDREVLTVSQLNGRARVLLEDVFSNIWVEGEISNLARPASGHVYFTLKDSGAQVRCALFRQNAARVRQAL
KDGLAVKVRGKVSLFEGRGDYQLILDTVEPAGDGALRLAFDALKEKLSAEGLFSAERKVPLPAHPQRIGIISSPTGAVIR
DIISVFRRRAPQVQLTLIPTAVQGREATAQIVRALKLADARGFDALILARGGGSLEDLWCFNEEAVARAVDACVTPIVSA
VGHETDVSISDFVADVRAPTPSAAAELLAPDSSHLIRQVESLHRRLVMRMRDRLMRDRLRLEGMTRRLRHPGERLRQQAQ
RLDDLDMRMRRAFERQLNTRRERLIRLETRLAGQHPGRQLALLRQRLDSLAERLPRAMNEGLKRRRLQLQSQMQTLHVVS
PLATLGRGYSILLDERGNAIRNAAQTHTGQRLKARLGEGELQVRVEDNHLTPVTLSLLD

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=445, Percent_Identity=44.9438202247191, Blast_Score=359, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 51327; Mature: 51327

Theoretical pI: Translated: 11.31; Mature: 11.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKDPFARLGLDREVLTVSQLNGRARVLLEDVFSNIWVEGEISNLARPASGHVYFTLKDS
CCCCCHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCEECCCHHHCCCCCCCEEEEEEECC
GAQVRCALFRQNAARVRQALKDGLAVKVRGKVSLFEGRGDYQLILDTVEPAGDGALRLAF
CCEEEHHHHHHHHHHHHHHHHCCCEEEEECEEEEEECCCCEEEEEECCCCCCCCHHHHHH
DALKEKLSAEGLFSAERKVPLPAHPQRIGIISSPTGAVIRDIISVFRRRAPQVQLTLIPT
HHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECC
AVQGREATAQIVRALKLADARGFDALILARGGGSLEDLWCFNEEAVARAVDACVTPIVSA
CCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHHHH
VGHETDVSISDFVADVRAPTPSAAAELLAPDSSHLIRQVESLHRRLVMRMRDRLMRDRLR
HCCCCCCCHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEGMTRRLRHPGERLRQQAQRLDDLDMRMRRAFERQLNTRRERLIRLETRLAGQHPGRQL
HHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
ALLRQRLDSLAERLPRAMNEGLKRRRLQLQSQMQTLHVVSPLATLGRGYSILLDERGNAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHH
RNAAQTHTGQRLKARLGEGELQVRVEDNHLTPVTLSLLD
HHHHHHCCCHHHHHHCCCCEEEEEEECCCCCEEEEEECC
>Mature Secondary Structure
MIKDPFARLGLDREVLTVSQLNGRARVLLEDVFSNIWVEGEISNLARPASGHVYFTLKDS
CCCCCHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCEECCCHHHCCCCCCCEEEEEEECC
GAQVRCALFRQNAARVRQALKDGLAVKVRGKVSLFEGRGDYQLILDTVEPAGDGALRLAF
CCEEEHHHHHHHHHHHHHHHHCCCEEEEECEEEEEECCCCEEEEEECCCCCCCCHHHHHH
DALKEKLSAEGLFSAERKVPLPAHPQRIGIISSPTGAVIRDIISVFRRRAPQVQLTLIPT
HHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECC
AVQGREATAQIVRALKLADARGFDALILARGGGSLEDLWCFNEEAVARAVDACVTPIVSA
CCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHHHH
VGHETDVSISDFVADVRAPTPSAAAELLAPDSSHLIRQVESLHRRLVMRMRDRLMRDRLR
HCCCCCCCHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEGMTRRLRHPGERLRQQAQRLDDLDMRMRRAFERQLNTRRERLIRLETRLAGQHPGRQL
HHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
ALLRQRLDSLAERLPRAMNEGLKRRRLQLQSQMQTLHVVSPLATLGRGYSILLDERGNAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHH
RNAAQTHTGQRLKARLGEGELQVRVEDNHLTPVTLSLLD
HHHHHHCCCHHHHHHCCCCEEEEEEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA