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The map label for this gene is cmoA [H]

Identifier: 77460803

GI number: 77460803

Start: 5178780

End: 5179523

Strand: Direct

Name: cmoA [H]

Synonym: Pfl01_4582

Alternate gene names: 77460803

Gene position: 5178780-5179523 (Clockwise)

Preceding gene: 77460802

Following gene: 77460804

Centisome position: 80.44

GC content: 61.29

Gene sequence:

>744_bases
GTGAGCAAAGAACCCGATCGCATTTTCGCCCAGCCGATGGCCCAGGTGCCTGACTTCGCCTTCAACGAAGACGTGGTGCG
GGTGTTCCCGGACATGATCAAGCGCTCGGTGCCGGGTTATCCGACCATCGTCGAAAATCTCGGCGTGCTCGCGGCACAAT
TTGCTCAGCCGAACAGCGTGCTCTACGACCTCGGCGCCTCCCTCGGAGCGGTGACCCAGGCATTACGTCGCCACGTGCGC
ACCGACGGTTGCCGGGTGATCGCGGTGGATAACTCGGCGGCGATGGTCGAGCGCTGCCGCGAGTACCTCAACGGTCAGGA
TTCGATGTTCCAGGAGTTGCTGCCGGTCGAGGTGATCGAAGGCGACATCCTCGCCCTCGACTTCAAACCGGCCTCGGTGG
TGGCGCTGAACTTCACCCTGCAATTCATCGCTCCGGATCAGCGTACGGCATTGCTGTCGCGCATTCGCCAATCATTGTTG
CCGGGCGGCGCGCTGATTCTGTCGGAGAAGCTGCGCTTCAACGATGCCGAAGAACATGCGCTGCTGACCGATCTGCACGT
CGCGTTCAAGCGCGCCAACGGTTACAGCGAACTGGAAATCGCCCAGAAGCGCAGCGCCATCGAAAACGTCATGAAGCCCG
ACAGCCTCGAAGAACACCGCGAGCGCCTGCTGGCCGCCGGGTTCTCGAAGGTCGTGCCGTGGTTCCAGTGTCTTAACTTT
GCCTCGTTGATTGCCTTGCCATGA

Upstream 100 bases:

>100_bases
CGTCCGGAGCTTTGAACCAGCGGTTTATCAGACAACCCGCGCATCTGCGCGCCAGTTTGGCTAAAATGCCGGCCTTTTCA
TCGACACCGCCGGAACCGCC

Downstream 100 bases:

>100_bases
TTGATCTGTCCCCCCTCGCCCGCCGTCTGGCCGGCACGCCGCTGGCCGAATGGGCCAACACCCTGCAAGTGCAGCTCGAC
AAAAAAATGGAGAAAGGCCA

Product: methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MSKEPDRIFAQPMAQVPDFAFNEDVVRVFPDMIKRSVPGYPTIVENLGVLAAQFAQPNSVLYDLGASLGAVTQALRRHVR
TDGCRVIAVDNSAAMVERCREYLNGQDSMFQELLPVEVIEGDILALDFKPASVVALNFTLQFIAPDQRTALLSRIRQSLL
PGGALILSEKLRFNDAEEHALLTDLHVAFKRANGYSELEIAQKRSAIENVMKPDSLEEHRERLLAAGFSKVVPWFQCLNF
ASLIALP

Sequences:

>Translated_247_residues
MSKEPDRIFAQPMAQVPDFAFNEDVVRVFPDMIKRSVPGYPTIVENLGVLAAQFAQPNSVLYDLGASLGAVTQALRRHVR
TDGCRVIAVDNSAAMVERCREYLNGQDSMFQELLPVEVIEGDILALDFKPASVVALNFTLQFIAPDQRTALLSRIRQSLL
PGGALILSEKLRFNDAEEHALLTDLHVAFKRANGYSELEIAQKRSAIENVMKPDSLEEHRERLLAAGFSKVVPWFQCLNF
ASLIALP
>Mature_246_residues
SKEPDRIFAQPMAQVPDFAFNEDVVRVFPDMIKRSVPGYPTIVENLGVLAAQFAQPNSVLYDLGASLGAVTQALRRHVRT
DGCRVIAVDNSAAMVERCREYLNGQDSMFQELLPVEVIEGDILALDFKPASVVALNFTLQFIAPDQRTALLSRIRQSLLP
GGALILSEKLRFNDAEEHALLTDLHVAFKRANGYSELEIAQKRSAIENVMKPDSLEEHRERLLAAGFSKVVPWFQCLNFA
SLIALP

Specific function: Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. CmoA family [H]

Homologues:

Organism=Escherichia coli, GI1788177, Length=241, Percent_Identity=54.356846473029, Blast_Score=275, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR005271 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 27453; Mature: 27322

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKEPDRIFAQPMAQVPDFAFNEDVVRVFPDMIKRSVPGYPTIVENLGVLAAQFAQPNSV
CCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHH
LYDLGASLGAVTQALRRHVRTDGCRVIAVDNSAAMVERCREYLNGQDSMFQELLPVEVIE
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCHHHHHHHHCCHHHCC
GDILALDFKPASVVALNFTLQFIAPDQRTALLSRIRQSLLPGGALILSEKLRFNDAEEHA
CCEEEEECCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEHHHHCCCCCHHHH
LLTDLHVAFKRANGYSELEIAQKRSAIENVMKPDSLEEHRERLLAAGFSKVVPWFQCLNF
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ASLIALP
HHHHCCC
>Mature Secondary Structure 
SKEPDRIFAQPMAQVPDFAFNEDVVRVFPDMIKRSVPGYPTIVENLGVLAAQFAQPNSV
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHH
LYDLGASLGAVTQALRRHVRTDGCRVIAVDNSAAMVERCREYLNGQDSMFQELLPVEVIE
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCHHHHHHHHCCHHHCC
GDILALDFKPASVVALNFTLQFIAPDQRTALLSRIRQSLLPGGALILSEKLRFNDAEEHA
CCEEEEECCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEHHHHCCCCCHHHH
LLTDLHVAFKRANGYSELEIAQKRSAIENVMKPDSLEEHRERLLAAGFSKVVPWFQCLNF
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ASLIALP
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA