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The map label for this gene is argF [H]

Identifier: 77460748

GI number: 77460748

Start: 5100992

End: 5101915

Strand: Direct

Name: argF [H]

Synonym: Pfl01_4527

Alternate gene names: 77460748

Gene position: 5100992-5101915 (Clockwise)

Preceding gene: 77460744

Following gene: 77460749

Centisome position: 79.23

GC content: 62.23

Gene sequence:

>924_bases
ATGATGAGCGCAAGGCACTTTCTCTCCCTGATGGATTGCACGCCCGAAGAGCTGGTCAGCGTGATCCGTCGAGGCGTTGA
GCTCAAGGACCTGCGTAACCGCGGCGTACTGTTCGAGCCTCTGAAAAACCGCGTCCTGGGGATGATCTTCGAGAAATCCT
CGACCCGTACCCGGATCTCCTTCGAGGCCGGCATGATCCAGCTCGGCGGCCAGGCGATCTTCCTGTCGCCGCGCGACACC
CAACTGGGTCGTGGCGAGCCGATCGGCGACTGCGCCATCGTCATGTCGAGCATGCTCGACGCAGTGATGATCCGTACCTT
TGCCCACAGCACCCTGACCGAATTCGCTGCCAACTCCCGCGTGCCGGTGATCAACGGCCTGTCCGATGACCTGCATCCGT
GTCAGTTGCTGGCCGACATGCAGACCTTCCTCGAACACCGCGGCTCCATCCAGGGCAAGACCGTGGCCTGGATCGGCGAC
GGCAACAACATGTGCAACAGCTATATAGAAGCGGCGATCCAGTTCGACTTCCAGTTGCGCGTGGCCTGCCCGGAAGGCTA
TGAGCCAAACCCTGAATTCGTGGCCAAGGCCGGTGACCGCGTGACCATCGTCCGCGACCCGAAAGACGCCGTGCGCGGCG
CGCATCTGGTGAGCACCGACGTCTGGACCTCCATGGGGCAGGAAGAGGAAACCGCCAAGCGCCTCAAACTGTTCGCGCCG
TTTCAGGTCAACCGCGCCCTGCTCGACCTGGCTGCCGATGACGTGCTATTCATGCACTGCCTGCCCGCTCACCGCGGTGA
GGAAATCAGCCTCGACCTGCTCGATGATCCGCGCTCCGTCGCCTGGGATCAGGCAGAAAACCGTCTCCACGCACAGAAGG
CCCTGCTCGAGTTCCTCGTCGAACCGGCATATCACCACGCATGA

Upstream 100 bases:

>100_bases
CCTATTTCGTCGCCCCCGTGCGGCTTACGCCGCAGGTCTCGCCCGTTGTTCCGATAAACAAGGCTTTGAGCATCTGCGGT
TTGTAGCAAAAAGGTAGTCA

Downstream 100 bases:

>100_bases
GTCATGAATTACTGCTGAACCTGCGCAACCTCGCTTGCGGCTATCAAGATCAACGTGTGGTGCAGAACCTCAACCTGCAC
CTCAACGCCGGTGACATTGG

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase 1; SOCT [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MMSARHFLSLMDCTPEELVSVIRRGVELKDLRNRGVLFEPLKNRVLGMIFEKSSTRTRISFEAGMIQLGGQAIFLSPRDT
QLGRGEPIGDCAIVMSSMLDAVMIRTFAHSTLTEFAANSRVPVINGLSDDLHPCQLLADMQTFLEHRGSIQGKTVAWIGD
GNNMCNSYIEAAIQFDFQLRVACPEGYEPNPEFVAKAGDRVTIVRDPKDAVRGAHLVSTDVWTSMGQEEETAKRLKLFAP
FQVNRALLDLAADDVLFMHCLPAHRGEEISLDLLDDPRSVAWDQAENRLHAQKALLEFLVEPAYHHA

Sequences:

>Translated_307_residues
MMSARHFLSLMDCTPEELVSVIRRGVELKDLRNRGVLFEPLKNRVLGMIFEKSSTRTRISFEAGMIQLGGQAIFLSPRDT
QLGRGEPIGDCAIVMSSMLDAVMIRTFAHSTLTEFAANSRVPVINGLSDDLHPCQLLADMQTFLEHRGSIQGKTVAWIGD
GNNMCNSYIEAAIQFDFQLRVACPEGYEPNPEFVAKAGDRVTIVRDPKDAVRGAHLVSTDVWTSMGQEEETAKRLKLFAP
FQVNRALLDLAADDVLFMHCLPAHRGEEISLDLLDDPRSVAWDQAENRLHAQKALLEFLVEPAYHHA
>Mature_307_residues
MMSARHFLSLMDCTPEELVSVIRRGVELKDLRNRGVLFEPLKNRVLGMIFEKSSTRTRISFEAGMIQLGGQAIFLSPRDT
QLGRGEPIGDCAIVMSSMLDAVMIRTFAHSTLTEFAANSRVPVINGLSDDLHPCQLLADMQTFLEHRGSIQGKTVAWIGD
GNNMCNSYIEAAIQFDFQLRVACPEGYEPNPEFVAKAGDRVTIVRDPKDAVRGAHLVSTDVWTSMGQEEETAKRLKLFAP
FQVNRALLDLAADDVLFMHCLPAHRGEEISLDLLDDPRSVAWDQAENRLHAQKALLEFLVEPAYHHA

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=295, Percent_Identity=41.0169491525424, Blast_Score=236, Evalue=2e-62,
Organism=Homo sapiens, GI18105007, Length=305, Percent_Identity=28.1967213114754, Blast_Score=100, Evalue=1e-21,
Organism=Escherichia coli, GI1786469, Length=325, Percent_Identity=35.3846153846154, Blast_Score=198, Evalue=5e-52,
Organism=Escherichia coli, GI1790703, Length=325, Percent_Identity=35.3846153846154, Blast_Score=197, Evalue=5e-52,
Organism=Escherichia coli, GI2367364, Length=308, Percent_Identity=27.9220779220779, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI48994908, Length=313, Percent_Identity=26.1980830670927, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193204318, Length=308, Percent_Identity=26.9480519480519, Blast_Score=74, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6322373, Length=320, Percent_Identity=33.4375, Blast_Score=183, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6322331, Length=313, Percent_Identity=27.4760383386581, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24642586, Length=286, Percent_Identity=27.972027972028, Blast_Score=90, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 34249; Mature: 34249

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSARHFLSLMDCTPEELVSVIRRGVELKDLRNRGVLFEPLKNRVLGMIFEKSSTRTRIS
CCCHHHHHHHHCCCHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHEEECCCCCEEEE
FEAGMIQLGGQAIFLSPRDTQLGRGEPIGDCAIVMSSMLDAVMIRTFAHSTLTEFAANSR
EECCEEEECCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VPVINGLSDDLHPCQLLADMQTFLEHRGSIQGKTVAWIGDGNNMCNSYIEAAIQFDFQLR
CCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHEEEEEEE
VACPEGYEPNPEFVAKAGDRVTIVRDPKDAVRGAHLVSTDVWTSMGQEEETAKRLKLFAP
EECCCCCCCCHHHHHCCCCEEEEEECCHHHHCCCHHHHHHHHHHCCCHHHHHHHHEEECC
FQVNRALLDLAADDVLFMHCLPAHRGEEISLDLLDDPRSVAWDQAENRLHAQKALLEFLV
HHHHHHHHHHHHHHHHEEHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
EPAYHHA
CHHHCCC
>Mature Secondary Structure
MMSARHFLSLMDCTPEELVSVIRRGVELKDLRNRGVLFEPLKNRVLGMIFEKSSTRTRIS
CCCHHHHHHHHCCCHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHEEECCCCCEEEE
FEAGMIQLGGQAIFLSPRDTQLGRGEPIGDCAIVMSSMLDAVMIRTFAHSTLTEFAANSR
EECCEEEECCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VPVINGLSDDLHPCQLLADMQTFLEHRGSIQGKTVAWIGDGNNMCNSYIEAAIQFDFQLR
CCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHEEEEEEE
VACPEGYEPNPEFVAKAGDRVTIVRDPKDAVRGAHLVSTDVWTSMGQEEETAKRLKLFAP
EECCCCCCCCHHHHHCCCCEEEEEECCHHHHCCCHHHHHHHHHHCCCHHHHHHHHEEECC
FQVNRALLDLAADDVLFMHCLPAHRGEEISLDLLDDPRSVAWDQAENRLHAQKALLEFLV
HHHHHHHHHHHHHHHHEEHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
EPAYHHA
CHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1522066 [H]