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The map label for this gene is argG [H]

Identifier: 77460738

GI number: 77460738

Start: 5091522

End: 5092739

Strand: Reverse

Name: argG [H]

Synonym: Pfl01_4517

Alternate gene names: 77460738

Gene position: 5092739-5091522 (Counterclockwise)

Preceding gene: 77460739

Following gene: 77460736

Centisome position: 79.1

GC content: 60.67

Gene sequence:

>1218_bases
ATGGCGGACGTAAACAAGGTCGTTCTGGCGTATTCCGGCGGCCTGGACACTTCGGTGATCCTCAAGTGGCTGCAGGATAC
TTATAACTGTGAAGTCGTGACCTTCACCGCTGACCTGGGTCAGGGCGAAGAGGTCGAGCCGGCTCGCGCCAAGGCGCAGG
CCATGGGCGTCAAAGAAATCTACATCGACGACCTGCGCGAAGAATTCGTGCGTGACTTCGTGTTCCCGATGTTCCGCGCC
AACACCGTTTACGAAGGCGAGTACCTGCTGGGTACTTCCATTGCGCGTCCGCTGATCGCCAAGCGTCTGATCGAAATCGC
CAACGAAACCGGCGCCGACGCCATTTCCCACGGCGCAACCGGCAAGGGCAACGACCAGGTGCGTTTCGAACTGGGTGCCT
ACGCGCTCAAGCCAGGCGTGAAAGTGATCGCCCCTTGGCGCGAGTGGGACCTGCTGTCCCGCGAGAAACTGATGGACTAC
GCCGAGAAGCACGCGATCCCGATCGAGCGTCACGGCAAGAAGAAATCCCCGTACTCGATGGACGCCAACCTGCTGCACAT
CTCCTATGAAGGCGGCGTGCTGGAAGACACCTGGACCGAGCACGAAGAAGACATGTGGCGCTGGACCGTCTCCCCGGAGA
AGGCTCCCGACACCCCGCAATACCTGGAACTGACCTACCGCAACGGCGACATCGTCGCGCTGGACGGCGTCGAAATGACT
CCGGCCACCGTACTGGCGACCCTGAACAGGATCGGTGGCGAGCACGGCATCGGCCGTCTGGACATCGTCGAGAACCGTTA
TGTCGGCATGAAGTCCCGTGGCTGCTACGAAACCCCGGGCGGCACCATCATGCTGCGCGCTCACCGCGCCATCGAATCGA
TCACCCTGGACCGCGAAGTCGCTCACCTCAAAGACGAGCTGATGCCGAAGTACGCCAGCCTGATCTACACCGGTTACTGG
TGGAGCCCTGAGCGTCTGATGCTGCAACAGATGATCGACGCTTCTCAGGTCAACGTGAACGGCGTTGTGCGCCTTAAGCT
GTACAAGGGCAACGTGATCGTGACCGGCCGCAAGTCCGACGATTCGCTGTTCGACGCCAACATCGCGACCTTCGAAGAAG
ACGGCGGCGCCTACAACCAGGCCGACGCGGCGGGCTTCATCAAGCTCAACGCACTGCGCATGCGTATTGCTGCCAACAAG
GGCCGCAAGTTGTTCTAA

Upstream 100 bases:

>100_bases
ATTCTGTCGCTTTGTCGTCTTAAGCTGTCGCGCCTCTGTAAATTATCGCGTTTGAGCGGTAGACTCCTCGGCTTTCCGTA
GAACCCCGTGGAGTGATGGC

Downstream 100 bases:

>100_bases
GTTCTTCGGGCCTGATGGAAAGAACGGCCTTGTCGTAGCGACAAGGCCGTTTTTTTTTTGGAGCGGGGGCTCGTTTGACT
TGATAGGTACCTGTCAGCGT

Product: argininosuccinate synthase

Products: NA

Alternate protein names: Citrulline--aspartate ligase [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MADVNKVVLAYSGGLDTSVILKWLQDTYNCEVVTFTADLGQGEEVEPARAKAQAMGVKEIYIDDLREEFVRDFVFPMFRA
NTVYEGEYLLGTSIARPLIAKRLIEIANETGADAISHGATGKGNDQVRFELGAYALKPGVKVIAPWREWDLLSREKLMDY
AEKHAIPIERHGKKKSPYSMDANLLHISYEGGVLEDTWTEHEEDMWRWTVSPEKAPDTPQYLELTYRNGDIVALDGVEMT
PATVLATLNRIGGEHGIGRLDIVENRYVGMKSRGCYETPGGTIMLRAHRAIESITLDREVAHLKDELMPKYASLIYTGYW
WSPERLMLQQMIDASQVNVNGVVRLKLYKGNVIVTGRKSDDSLFDANIATFEEDGGAYNQADAAGFIKLNALRMRIAANK
GRKLF

Sequences:

>Translated_405_residues
MADVNKVVLAYSGGLDTSVILKWLQDTYNCEVVTFTADLGQGEEVEPARAKAQAMGVKEIYIDDLREEFVRDFVFPMFRA
NTVYEGEYLLGTSIARPLIAKRLIEIANETGADAISHGATGKGNDQVRFELGAYALKPGVKVIAPWREWDLLSREKLMDY
AEKHAIPIERHGKKKSPYSMDANLLHISYEGGVLEDTWTEHEEDMWRWTVSPEKAPDTPQYLELTYRNGDIVALDGVEMT
PATVLATLNRIGGEHGIGRLDIVENRYVGMKSRGCYETPGGTIMLRAHRAIESITLDREVAHLKDELMPKYASLIYTGYW
WSPERLMLQQMIDASQVNVNGVVRLKLYKGNVIVTGRKSDDSLFDANIATFEEDGGAYNQADAAGFIKLNALRMRIAANK
GRKLF
>Mature_404_residues
ADVNKVVLAYSGGLDTSVILKWLQDTYNCEVVTFTADLGQGEEVEPARAKAQAMGVKEIYIDDLREEFVRDFVFPMFRAN
TVYEGEYLLGTSIARPLIAKRLIEIANETGADAISHGATGKGNDQVRFELGAYALKPGVKVIAPWREWDLLSREKLMDYA
EKHAIPIERHGKKKSPYSMDANLLHISYEGGVLEDTWTEHEEDMWRWTVSPEKAPDTPQYLELTYRNGDIVALDGVEMTP
ATVLATLNRIGGEHGIGRLDIVENRYVGMKSRGCYETPGGTIMLRAHRAIESITLDREVAHLKDELMPKYASLIYTGYWW
SPERLMLQQMIDASQVNVNGVVRLKLYKGNVIVTGRKSDDSLFDANIATFEEDGGAYNQADAAGFIKLNALRMRIAANKG
RKLF

Specific function: Arginine biosynthesis; seventh step. [C]

COG id: COG0137

COG function: function code E; Argininosuccinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the argininosuccinate synthase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI53759107, Length=404, Percent_Identity=46.7821782178218, Blast_Score=364, Evalue=1e-101,
Organism=Homo sapiens, GI16950633, Length=404, Percent_Identity=46.7821782178218, Blast_Score=364, Evalue=1e-101,
Organism=Escherichia coli, GI1789563, Length=367, Percent_Identity=26.9754768392371, Blast_Score=105, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6324514, Length=405, Percent_Identity=45.4320987654321, Blast_Score=348, Evalue=8e-97,
Organism=Drosophila melanogaster, GI21358151, Length=402, Percent_Identity=45.5223880597015, Blast_Score=342, Evalue=2e-94,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001518
- InterPro:   IPR018223
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00764 Arginosuc_synth [H]

EC number: =6.3.4.5 [H]

Molecular weight: Translated: 45420; Mature: 45289

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00564 ARGININOSUCCIN_SYN_1 ; PS00565 ARGININOSUCCIN_SYN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADVNKVVLAYSGGLDTSVILKWLQDTYNCEVVTFTADLGQGEEVEPARAKAQAMGVKEI
CCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHCCHHHH
YIDDLREEFVRDFVFPMFRANTVYEGEYLLGTSIARPLIAKRLIEIANETGADAISHGAT
HHHHHHHHHHHHHHHHHHHCCEEECCCEEECHHHHHHHHHHHHHHHHCCCCCHHHHCCCC
GKGNDQVRFELGAYALKPGVKVIAPWREWDLLSREKLMDYAEKHAIPIERHGKKKSPYSM
CCCCCEEEEEECCEEECCCCEEEECCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCC
DANLLHISYEGGVLEDTWTEHEEDMWRWTVSPEKAPDTPQYLELTYRNGDIVALDGVEMT
CCEEEEEEECCCEECCCCCCCCCCCEEEECCCCCCCCCCCEEEEEEECCCEEEECCCCCC
PATVLATLNRIGGEHGIGRLDIVENRYVGMKSRGCYETPGGTIMLRAHRAIESITLDREV
HHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCEECCCCEEEEEEHHHHHHHHHHHHH
AHLKDELMPKYASLIYTGYWWSPERLMLQQMIDASQVNVNGVVRLKLYKGNVIVTGRKSD
HHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHCCCCCCCCEEEEEEEEECCEEEEECCCC
DSLFDANIATFEEDGGAYNQADAAGFIKLNALRMRIAANKGRKLF
CCEEECCCEEEECCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCC
>Mature Secondary Structure 
ADVNKVVLAYSGGLDTSVILKWLQDTYNCEVVTFTADLGQGEEVEPARAKAQAMGVKEI
CCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHCCHHHH
YIDDLREEFVRDFVFPMFRANTVYEGEYLLGTSIARPLIAKRLIEIANETGADAISHGAT
HHHHHHHHHHHHHHHHHHHCCEEECCCEEECHHHHHHHHHHHHHHHHCCCCCHHHHCCCC
GKGNDQVRFELGAYALKPGVKVIAPWREWDLLSREKLMDYAEKHAIPIERHGKKKSPYSM
CCCCCEEEEEECCEEECCCCEEEECCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCC
DANLLHISYEGGVLEDTWTEHEEDMWRWTVSPEKAPDTPQYLELTYRNGDIVALDGVEMT
CCEEEEEEECCCEECCCCCCCCCCCEEEECCCCCCCCCCCEEEEEEECCCEEEECCCCCC
PATVLATLNRIGGEHGIGRLDIVENRYVGMKSRGCYETPGGTIMLRAHRAIESITLDREV
HHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCEECCCCEEEEEEHHHHHHHHHHHHH
AHLKDELMPKYASLIYTGYWWSPERLMLQQMIDASQVNVNGVVRLKLYKGNVIVTGRKSD
HHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHCCCCCCCCEEEEEEEEECCEEEEECCCC
DSLFDANIATFEEDGGAYNQADAAGFIKLNALRMRIAANKGRKLF
CCEEECCCEEEECCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA