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The map label for this gene is argJ

Identifier: 77460648

GI number: 77460648

Start: 4984211

End: 4985428

Strand: Reverse

Name: argJ

Synonym: Pfl01_4427

Alternate gene names: 77460648

Gene position: 4985428-4984211 (Counterclockwise)

Preceding gene: 255961263

Following gene: 77460647

Centisome position: 77.43

GC content: 63.55

Gene sequence:

>1218_bases
ATGGCTGTTGGTCTTGGTCCTTTGCCAACGTTGCACCCGGTTGCCGGTTTTGAACTCGGTATTGCTTCGGCCGGTATCAA
ACGCCCGGGGCGCAAGGATGTCGTCGTGATGCGTTGCGCCGAAGGTTCCACCGTGGCGGGCGTGTTTACGTTGAACGCTT
TCTGTGCAGCGCCGGTGATCCTGGCCAAGAAGCGCGTGCAGAACGCTGTGCGCTACCTGTTGACCAACACCGGCAACGCC
AACGCGGGCACCGGCGAGCCGGGCCTGGCCGCCGCCGAGCGTACGACCGCGAAGCTGGCCGAGCTGACCGGCGTCGATGC
CAGCCAGATTCTGCCGTACTCCACCGGCGTGATCGGCGAGCCGCTGCCGGTCGAGAAGATCGAAGGCGCCTTGCAAGCCG
CGCTGGACGATCTGTCGGAAAACAACTGGGAAGCTGCCGCCACTGGCATCATGACCACCGACACACTGCCAAAAGGCGCG
AGCCGCCAGTTCCAGCATGACGGCGTGACCATCACCGTCACCGGCATCAGCAAGGGTGCAGGCATGATTCGTCCGAACAT
GGCGACCATGCTCGGCTACATCGCCACCGACGCCAAAGTCTCTCGCGACGTGCTGCAAAACCTGATGCTGGACGGCGCCA
ACAAGTCGTTCAACCGCATCACTATCGACGGCGACACCTCGACCAACGACTGCTGCATGCTGATCGCTACCGGCAAGGCC
GCACTGCCGGAAATCAACCGCGCCGAAGGCGAACTGTTCGCCAAGCTGAAACAGGCCGTGTTTGAGGTGTGCATGGACGT
GGCCCAGGCCATCGTGCGTGACGGCGAAGGCGCGACCAAGTTCGTGACCGTTGAAGTCAACGGCGGCGGCAATCACCAGG
AATGCCTGGACGTCGGCTACACCGTGGCCCACTCGCCGCTGATCAAGACCGCGCTGTTCGCCTCGGACCCGAACTGGGGT
CGCATCCTCGCCGCTGTCGGCCGTGCCGGCGTGCCGGACCTGGATGTGAGCAAGATCGACGTGTTCCTCGGCGAGGTGTG
CATCGCCAGCCGTGGCGCGCGCGCCGCGACCTACACCGAAGCCCAGGGCTCGGCGGTGATGCAGCAGGAAGAAATCACCA
TCCGTATCGAACTGGGTCGCGGCGATTGCAGCGAAACCATCTGGACCACCGACCTGTCCCACGAGTACGTGAAGATCAAC
GCCGAATACCGCACCTGA

Upstream 100 bases:

>100_bases
ACCCGCGCCGCGACCGGCACCAGCCGTCGCGGCGTTTTGCCATTTACACCACCGTCACTACGCTTGGCGGTGCTGACATC
ATTGAGTAAGGAGCGCATTC

Downstream 100 bases:

>100_bases
TCCCTGCTGAAGAGGGAGGTCTGCGGACCTCCTTTTCTTCTGTCCCATGAAAGGACCCGAACATGAGCCTTCACCTGATC
ATCGGCGACAAACTGCTTTC

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MAVGLGPLPTLHPVAGFELGIASAGIKRPGRKDVVVMRCAEGSTVAGVFTLNAFCAAPVILAKKRVQNAVRYLLTNTGNA
NAGTGEPGLAAAERTTAKLAELTGVDASQILPYSTGVIGEPLPVEKIEGALQAALDDLSENNWEAAATGIMTTDTLPKGA
SRQFQHDGVTITVTGISKGAGMIRPNMATMLGYIATDAKVSRDVLQNLMLDGANKSFNRITIDGDTSTNDCCMLIATGKA
ALPEINRAEGELFAKLKQAVFEVCMDVAQAIVRDGEGATKFVTVEVNGGGNHQECLDVGYTVAHSPLIKTALFASDPNWG
RILAAVGRAGVPDLDVSKIDVFLGEVCIASRGARAATYTEAQGSAVMQQEEITIRIELGRGDCSETIWTTDLSHEYVKIN
AEYRT

Sequences:

>Translated_405_residues
MAVGLGPLPTLHPVAGFELGIASAGIKRPGRKDVVVMRCAEGSTVAGVFTLNAFCAAPVILAKKRVQNAVRYLLTNTGNA
NAGTGEPGLAAAERTTAKLAELTGVDASQILPYSTGVIGEPLPVEKIEGALQAALDDLSENNWEAAATGIMTTDTLPKGA
SRQFQHDGVTITVTGISKGAGMIRPNMATMLGYIATDAKVSRDVLQNLMLDGANKSFNRITIDGDTSTNDCCMLIATGKA
ALPEINRAEGELFAKLKQAVFEVCMDVAQAIVRDGEGATKFVTVEVNGGGNHQECLDVGYTVAHSPLIKTALFASDPNWG
RILAAVGRAGVPDLDVSKIDVFLGEVCIASRGARAATYTEAQGSAVMQQEEITIRIELGRGDCSETIWTTDLSHEYVKIN
AEYRT
>Mature_404_residues
AVGLGPLPTLHPVAGFELGIASAGIKRPGRKDVVVMRCAEGSTVAGVFTLNAFCAAPVILAKKRVQNAVRYLLTNTGNAN
AGTGEPGLAAAERTTAKLAELTGVDASQILPYSTGVIGEPLPVEKIEGALQAALDDLSENNWEAAATGIMTTDTLPKGAS
RQFQHDGVTITVTGISKGAGMIRPNMATMLGYIATDAKVSRDVLQNLMLDGANKSFNRITIDGDTSTNDCCMLIATGKAA
LPEINRAEGELFAKLKQAVFEVCMDVAQAIVRDGEGATKFVTVEVNGGGNHQECLDVGYTVAHSPLIKTALFASDPNWGR
ILAAVGRAGVPDLDVSKIDVFLGEVCIASRGARAATYTEAQGSAVMQQEEITIRIELGRGDCSETIWTTDLSHEYVKINA
EYRT

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=413, Percent_Identity=37.772397094431, Blast_Score=259, Evalue=6e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGJ_PSEPF (Q3K7U0)

Other databases:

- EMBL:   CP000094
- RefSeq:   YP_350155.1
- ProteinModelPortal:   Q3K7U0
- SMR:   Q3K7U0
- STRING:   Q3K7U0
- MEROPS:   T05.001
- World-2DPAGE:   0008:Q3K7U0
- GeneID:   3713466
- GenomeReviews:   CP000094_GR
- KEGG:   pfo:Pfl01_4427
- eggNOG:   COG1364
- HOGENOM:   HBG284202
- OMA:   QNRFCAA
- ProtClustDB:   PRK05388
- BioCyc:   PFLU205922:PFL_4427-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01106
- InterPro:   IPR002813
- InterPro:   IPR016117
- PANTHER:   PTHR23100
- TIGRFAMs:   TIGR00120

Pfam domain/function: PF01960 ArgJ; SSF56266 Pept_S58_DmpA/Arg_biosyn_ArgJ

EC number: =2.3.1.35; =2.3.1.1

Molecular weight: Translated: 42598; Mature: 42467

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVGLGPLPTLHPVAGFELGIASAGIKRPGRKDVVVMRCAEGSTVAGVFTLNAFCAAPVI
CCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCEEEEEECCCCEEEEEEEHHHHHHHHHH
LAKKRVQNAVRYLLTNTGNANAGTGEPGLAAAERTTAKLAELTGVDASQILPYSTGVIGE
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCCCC
PLPVEKIEGALQAALDDLSENNWEAAATGIMTTDTLPKGASRQFQHDGVTITVTGISKGA
CCCHHHHHHHHHHHHHHHCCCCCCHHHCCEEEECCCCCCCCCCCCCCCEEEEEEECCCCC
GMIRPNMATMLGYIATDAKVSRDVLQNLMLDGANKSFNRITIDGDTSTNDCCMLIATGKA
CCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEEEECCCC
ALPEINRAEGELFAKLKQAVFEVCMDVAQAIVRDGEGATKFVTVEVNGGGNHQECLDVGY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHCH
TVAHSPLIKTALFASDPNWGRILAAVGRAGVPDLDVSKIDVFLGEVCIASRGARAATYTE
HHHCCHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEC
AQGSAVMQQEEITIRIELGRGDCSETIWTTDLSHEYVKINAEYRT
CCCCEEEEECEEEEEEEECCCCCCCCEEEECCCCEEEEEEEEECC
>Mature Secondary Structure 
AVGLGPLPTLHPVAGFELGIASAGIKRPGRKDVVVMRCAEGSTVAGVFTLNAFCAAPVI
CCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCEEEEEECCCCEEEEEEEHHHHHHHHHH
LAKKRVQNAVRYLLTNTGNANAGTGEPGLAAAERTTAKLAELTGVDASQILPYSTGVIGE
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCCCC
PLPVEKIEGALQAALDDLSENNWEAAATGIMTTDTLPKGASRQFQHDGVTITVTGISKGA
CCCHHHHHHHHHHHHHHHCCCCCCHHHCCEEEECCCCCCCCCCCCCCCEEEEEEECCCCC
GMIRPNMATMLGYIATDAKVSRDVLQNLMLDGANKSFNRITIDGDTSTNDCCMLIATGKA
CCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEEEECCCC
ALPEINRAEGELFAKLKQAVFEVCMDVAQAIVRDGEGATKFVTVEVNGGGNHQECLDVGY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHCH
TVAHSPLIKTALFASDPNWGRILAAVGRAGVPDLDVSKIDVFLGEVCIASRGARAATYTE
HHHCCHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEC
AQGSAVMQQEEITIRIELGRGDCSETIWTTDLSHEYVKINAEYRT
CCCCEEEEECEEEEEEEECCCCCCCCEEEECCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA