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The map label for this gene is sdaA [H]

Identifier: 77460614

GI number: 77460614

Start: 4954353

End: 4955729

Strand: Direct

Name: sdaA [H]

Synonym: Pfl01_4393

Alternate gene names: 77460614

Gene position: 4954353-4955729 (Clockwise)

Preceding gene: 77460613

Following gene: 77460615

Centisome position: 76.95

GC content: 63.62

Gene sequence:

>1377_bases
ATGTCGTTAAGCGTGTTCGACCTGTTCAAGATTGGCATCGGCCCCTCCAGCTCCCACACCGTCGGCCCGATGCGCGCAGC
TGCGCGCTTCGTGGAAGGTCTGCGCCGGGAAAACCTGTTGTCGGCCACCACCAGCGTCAGGGTCGAGTTGTATGGATCCC
TCGGCGCCACGGGCAAGGGTCACGGCAGCGACAAGGCCGTGCTGCTGGGCCTGGAAGGTGAACACCCGGACACCGTGGAT
ACTGAAACCGTCGCCGCCCGTCTCGCGGAGATTCGTGGCAACGGGCGTTTGATCCTGCTCGGTGAACACAGCATTGCGTT
CAACGAGAAAGAACACCTGGCAATGATCCGCAAGCCGTTGGCCTATCACCCCAACGGCATGATCTTCCGCGCCTTCGATG
CGGCGGGATTGCAGATCCGCAGCCGCGAGTACTACTCGGTCGGCGGTGGGTTTGTGGTCGACGAAGACGCGGCCGGCGCC
GACCGGATCGTCGAAGACGCCACCCCGCTGACCTTCCCGTTCAAAAGTGCCAAGGACTTGCTCGGTCATTGCGCCACCTA
TGGTCTGTCGATCAGTCAGGTGATGCTGGCCAACGAAAGCGCCTGGCGCCCGGAGGCGGAAACCCGTGCCGGCCTGCTGA
AAATCTGGCAAGTGATGCAGGACTGTGTGGCCGCCGGCTGTCGCAACGAAGGCATTCTGCCGGGTGGCCTCAAGGTCAAG
CGGCGGGCGGCGGCGTTGCACCGGCAACTGTGCAAGAACCCGGAATCGTCGCTGCGCGATCCGCTGTCGGTGCTGGACTG
GGTCAACCTCTACGCCCTCGCTGTCAACGAAGAAAACGCCAACGGCGGGCGCGTGGTCACGGCACCGACCAACGGCGCGG
CGGGGATCATTCCTGCGGTGCTGCATTACTACATGCGCTTCATTCCCGGCGCGAACGATGACGGCGTGGTGCGTTTCCTG
CTCACCGCCGCGGCCATCGGCATTCTGTACAAGGAAAACGCCTCGATTTCCGGTGCCGAAGTCGGCTGTCAGGGCGAGGT
CGGCGTGGCCTGTTCGATGGCGGCCGGCGCGTTGTGCGAAGTCCTCGGCGGCAGCGTGCAACAAGTGGAAAACGCCGCCG
AAATCGGCATGGAACACAACCTCGGCCTGACCTGCGACCCGATTGGCGGACTGGTGCAAGTGCCGTGCATCGAGCGCAAC
GCCATGGGTTCGGTCAAGGCGATCAACGCCGTGCGCATGGCCATGCGCGGAGACGGGCAGCACTTCGTCTCCCTCGACAA
GGTCATCCGCACCATGCGCCAGACCGGCGCCGACATGAAAAGCAAATACAAGGAGACCGCCCGTGGCGGTCTGGCGGTCA
ACATTATCGAGTGCTGA

Upstream 100 bases:

>100_bases
CACAGTTCCCCATGTGGGAGCGGGCTTGCTCGCTCCCACAAGGAAATGCATCAAGCCTGAAATCCCGCCAATTCCTATAA
CAAGAAACCGGAGAACAACC

Downstream 100 bases:

>100_bases
TCGCGCCATAAACTCGCTCTCCCTTTGGGAGAGAACACAAAACTGGCCCCCTCTCCCTCCGGGAGAGGGTTGGTGTGAAT
CAAGGAGTCACGCATGTCCA

Product: L-serine ammonia-lyase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MSLSVFDLFKIGIGPSSSHTVGPMRAAARFVEGLRRENLLSATTSVRVELYGSLGATGKGHGSDKAVLLGLEGEHPDTVD
TETVAARLAEIRGNGRLILLGEHSIAFNEKEHLAMIRKPLAYHPNGMIFRAFDAAGLQIRSREYYSVGGGFVVDEDAAGA
DRIVEDATPLTFPFKSAKDLLGHCATYGLSISQVMLANESAWRPEAETRAGLLKIWQVMQDCVAAGCRNEGILPGGLKVK
RRAAALHRQLCKNPESSLRDPLSVLDWVNLYALAVNEENANGGRVVTAPTNGAAGIIPAVLHYYMRFIPGANDDGVVRFL
LTAAAIGILYKENASISGAEVGCQGEVGVACSMAAGALCEVLGGSVQQVENAAEIGMEHNLGLTCDPIGGLVQVPCIERN
AMGSVKAINAVRMAMRGDGQHFVSLDKVIRTMRQTGADMKSKYKETARGGLAVNIIEC

Sequences:

>Translated_458_residues
MSLSVFDLFKIGIGPSSSHTVGPMRAAARFVEGLRRENLLSATTSVRVELYGSLGATGKGHGSDKAVLLGLEGEHPDTVD
TETVAARLAEIRGNGRLILLGEHSIAFNEKEHLAMIRKPLAYHPNGMIFRAFDAAGLQIRSREYYSVGGGFVVDEDAAGA
DRIVEDATPLTFPFKSAKDLLGHCATYGLSISQVMLANESAWRPEAETRAGLLKIWQVMQDCVAAGCRNEGILPGGLKVK
RRAAALHRQLCKNPESSLRDPLSVLDWVNLYALAVNEENANGGRVVTAPTNGAAGIIPAVLHYYMRFIPGANDDGVVRFL
LTAAAIGILYKENASISGAEVGCQGEVGVACSMAAGALCEVLGGSVQQVENAAEIGMEHNLGLTCDPIGGLVQVPCIERN
AMGSVKAINAVRMAMRGDGQHFVSLDKVIRTMRQTGADMKSKYKETARGGLAVNIIEC
>Mature_457_residues
SLSVFDLFKIGIGPSSSHTVGPMRAAARFVEGLRRENLLSATTSVRVELYGSLGATGKGHGSDKAVLLGLEGEHPDTVDT
ETVAARLAEIRGNGRLILLGEHSIAFNEKEHLAMIRKPLAYHPNGMIFRAFDAAGLQIRSREYYSVGGGFVVDEDAAGAD
RIVEDATPLTFPFKSAKDLLGHCATYGLSISQVMLANESAWRPEAETRAGLLKIWQVMQDCVAAGCRNEGILPGGLKVKR
RAAALHRQLCKNPESSLRDPLSVLDWVNLYALAVNEENANGGRVVTAPTNGAAGIIPAVLHYYMRFIPGANDDGVVRFLL
TAAAIGILYKENASISGAEVGCQGEVGVACSMAAGALCEVLGGSVQQVENAAEIGMEHNLGLTCDPIGGLVQVPCIERNA
MGSVKAINAVRMAMRGDGQHFVSLDKVIRTMRQTGADMKSKYKETARGGLAVNIIEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1789161, Length=459, Percent_Identity=54.2483660130719, Blast_Score=486, Evalue=1e-138,
Organism=Escherichia coli, GI1788116, Length=454, Percent_Identity=54.1850220264317, Blast_Score=482, Evalue=1e-137,
Organism=Escherichia coli, GI48994925, Length=455, Percent_Identity=54.9450549450549, Blast_Score=479, Evalue=1e-136,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 48702; Mature: 48570

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSVFDLFKIGIGPSSSHTVGPMRAAARFVEGLRRENLLSATTSVRVELYGSLGATGKG
CCCCCEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCC
HGSDKAVLLGLEGEHPDTVDTETVAARLAEIRGNGRLILLGEHSIAFNEKEHLAMIRKPL
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHCH
AYHPNGMIFRAFDAAGLQIRSREYYSVGGGFVVDEDAAGADRIVEDATPLTFPFKSAKDL
HCCCCCCEEEEECCCCCEEECCEEEECCCCEEEECCCCCHHHHHHCCCCCEECCHHHHHH
LGHCATYGLSISQVMLANESAWRPEAETRAGLLKIWQVMQDCVAAGCRNEGILPGGLKVK
HHHHHHHCCCHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
RRAAALHRQLCKNPESSLRDPLSVLDWVNLYALAVNEENANGGRVVTAPTNGAAGIIPAV
HHHHHHHHHHHCCCHHHHHCHHHHHHHHHEEEEEEECCCCCCCEEEECCCCCCCHHHHHH
LHYYMRFIPGANDDGVVRFLLTAAAIGILYKENASISGAEVGCQGEVGVACSMAAGALCE
HHHHHHHCCCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
VLGGSVQQVENAAEIGMEHNLGLTCDPIGGLVQVPCIERNAMGSVKAINAVRMAMRGDGQ
HHCCHHHHHHHHHHCCCCCCCCEEECCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCCH
HFVSLDKVIRTMRQTGADMKSKYKETARGGLAVNIIEC
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEEC
>Mature Secondary Structure 
SLSVFDLFKIGIGPSSSHTVGPMRAAARFVEGLRRENLLSATTSVRVELYGSLGATGKG
CCCCEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCC
HGSDKAVLLGLEGEHPDTVDTETVAARLAEIRGNGRLILLGEHSIAFNEKEHLAMIRKPL
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHCH
AYHPNGMIFRAFDAAGLQIRSREYYSVGGGFVVDEDAAGADRIVEDATPLTFPFKSAKDL
HCCCCCCEEEEECCCCCEEECCEEEECCCCEEEECCCCCHHHHHHCCCCCEECCHHHHHH
LGHCATYGLSISQVMLANESAWRPEAETRAGLLKIWQVMQDCVAAGCRNEGILPGGLKVK
HHHHHHHCCCHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
RRAAALHRQLCKNPESSLRDPLSVLDWVNLYALAVNEENANGGRVVTAPTNGAAGIIPAV
HHHHHHHHHHHCCCHHHHHCHHHHHHHHHEEEEEEECCCCCCCEEEECCCCCCCHHHHHH
LHYYMRFIPGANDDGVVRFLLTAAAIGILYKENASISGAEVGCQGEVGVACSMAAGALCE
HHHHHHHCCCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
VLGGSVQQVENAAEIGMEHNLGLTCDPIGGLVQVPCIERNAMGSVKAINAVRMAMRGDGQ
HHCCHHHHHHHHHHCCCCCCCCEEECCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCCH
HFVSLDKVIRTMRQTGADMKSKYKETARGGLAVNIIEC
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]