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The map label for this gene is oprB [H]

Identifier: 77460587

GI number: 77460587

Start: 4918743

End: 4920089

Strand: Reverse

Name: oprB [H]

Synonym: Pfl01_4366

Alternate gene names: 77460587

Gene position: 4920089-4918743 (Counterclockwise)

Preceding gene: 77460588

Following gene: 77460586

Centisome position: 76.42

GC content: 57.39

Gene sequence:

>1347_bases
ATGAAGAAGAACAACAACGCTCAGCGAATCGGCCAGTTGTCAGCGGTTGCGGCAATGATGCTGGCCGGCAGCGTCCACGC
GGCTGACGCGTTCAGCTCCGATTCGGAGTGGATGACCGGGGACTGGGGTGGCGAACGTACCAAGCTGATCGAGCAGGGTA
TCGACATCAAGATGGACTACGTCGGTGAGGTGGGCGGCAACCTGCACGGCGGCTACAACAACGACAAGACGGCGCGTTAC
TCCGACCAGTTCGGTCTGGGCGTGGCGCTGGACCTGCAAAAACTGTGGGGCTGGGACAACACCCAGGCCAAGATCCAGCT
GACCAACCGTAATGGCGAAAACATTTCCAACGATCGTGTTGGCGATCCGCGTGCCGGCACACTCAGCTCCTCGCAGGAAG
TCTACGGTCGTGGCCACATGGTGCGTCTGACCCAGTTGTGGATCAAACACCAGTTCTTCGACAACAAGCTCGACGTCAAG
GCCGGTTACTTCGGCGAAGGCGAAGACTTCAACACCTTCCCGTGCGAGTTCCAGAACCTGGCGTTCTGCGGTTCGCAAGT
GGGTAACTGGGCGACCAACATCTGGTACAACTGGCCAGTCAGCCAGGCGGCGATTCGCGTCAAGTACAACATCAACGACG
AGCTCTACGCGCAGATCGGTGCGTACAACCAGAACCCGTCGCAACTGGAACACGGCAACGGCTTCAAGTTGAGCGGCAGC
GGCACCAAAGGCACCGTGTTGCCAGTGGAACTGGTCTGGTCGCCTAACCCGAACGGCCTGCCGGGCGAATACCGTGTCGG
TTACTACAAGAGCACGGCCGATGCCGACGACGTTCGCGAAGACGTCAACGGTTTCGACGCTGCGACCACCGGTGATGCCT
ACCGTACCCACAGCAGCAAGCACGGTTACTGGTTCGTTGCACAGCAGCAACTCACCAGCCACAACGGTGACAAGAGCCGT
GGTCTGAGCATTGCTGCCAACGCTACGTTCCACGACAAGGACACCAACTTCATCGACAACTATCAGTCCGTGATGTTTGT
GTACAAAGGCCCGTTCGATGCGCGTCCGAAGGATGACTTCGGTATTGGTGCTGCGCGTATTCACGTCAACGATGACGTGA
AGAAAAACGCCGAACTGCTCAACGTCTCCAACGGTGTTTCGGACTACGACAATCCGGTGTTCGCGCCGATTCGTGAAACC
GAATACAACTACGAGATCAACTACGGCTTCCATGTGACCAACTGGCTGACCGTACGCCCGAACCTGCAATACATCACTCA
TCCGGGCGGTGTGGATGAAGTGGATAACGCTTTGGTCGCTGGCCTGAAAATTCAGTCTACGTTCTGA

Upstream 100 bases:

>100_bases
CGCAGGGAGCACGCGGTGCGTGGCCTGTCGCGCGCCGCATCAGATGTAAACCGCGTTAGATAAGAAGAACAGTTAATAAC
AATAAAACGAGGATGTAGGG

Downstream 100 bases:

>100_bases
CGCGTCTGCGATAAGCTCCTCTCTATGTGCGCATATTTGCGGACAGCCAAGGCTGTCCGCTTTTTTTTGGACAGGGGTGT
CGCAGCCCATGAAAGTTGAT

Product: carbohydrate-selective porin OprB

Products: NA

Alternate protein names: Glucose porin; Outer membrane protein D1 [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MKKNNNAQRIGQLSAVAAMMLAGSVHAADAFSSDSEWMTGDWGGERTKLIEQGIDIKMDYVGEVGGNLHGGYNNDKTARY
SDQFGLGVALDLQKLWGWDNTQAKIQLTNRNGENISNDRVGDPRAGTLSSSQEVYGRGHMVRLTQLWIKHQFFDNKLDVK
AGYFGEGEDFNTFPCEFQNLAFCGSQVGNWATNIWYNWPVSQAAIRVKYNINDELYAQIGAYNQNPSQLEHGNGFKLSGS
GTKGTVLPVELVWSPNPNGLPGEYRVGYYKSTADADDVREDVNGFDAATTGDAYRTHSSKHGYWFVAQQQLTSHNGDKSR
GLSIAANATFHDKDTNFIDNYQSVMFVYKGPFDARPKDDFGIGAARIHVNDDVKKNAELLNVSNGVSDYDNPVFAPIRET
EYNYEINYGFHVTNWLTVRPNLQYITHPGGVDEVDNALVAGLKIQSTF

Sequences:

>Translated_448_residues
MKKNNNAQRIGQLSAVAAMMLAGSVHAADAFSSDSEWMTGDWGGERTKLIEQGIDIKMDYVGEVGGNLHGGYNNDKTARY
SDQFGLGVALDLQKLWGWDNTQAKIQLTNRNGENISNDRVGDPRAGTLSSSQEVYGRGHMVRLTQLWIKHQFFDNKLDVK
AGYFGEGEDFNTFPCEFQNLAFCGSQVGNWATNIWYNWPVSQAAIRVKYNINDELYAQIGAYNQNPSQLEHGNGFKLSGS
GTKGTVLPVELVWSPNPNGLPGEYRVGYYKSTADADDVREDVNGFDAATTGDAYRTHSSKHGYWFVAQQQLTSHNGDKSR
GLSIAANATFHDKDTNFIDNYQSVMFVYKGPFDARPKDDFGIGAARIHVNDDVKKNAELLNVSNGVSDYDNPVFAPIRET
EYNYEINYGFHVTNWLTVRPNLQYITHPGGVDEVDNALVAGLKIQSTF
>Mature_448_residues
MKKNNNAQRIGQLSAVAAMMLAGSVHAADAFSSDSEWMTGDWGGERTKLIEQGIDIKMDYVGEVGGNLHGGYNNDKTARY
SDQFGLGVALDLQKLWGWDNTQAKIQLTNRNGENISNDRVGDPRAGTLSSSQEVYGRGHMVRLTQLWIKHQFFDNKLDVK
AGYFGEGEDFNTFPCEFQNLAFCGSQVGNWATNIWYNWPVSQAAIRVKYNINDELYAQIGAYNQNPSQLEHGNGFKLSGS
GTKGTVLPVELVWSPNPNGLPGEYRVGYYKSTADADDVREDVNGFDAATTGDAYRTHSSKHGYWFVAQQQLTSHNGDKSR
GLSIAANATFHDKDTNFIDNYQSVMFVYKGPFDARPKDDFGIGAARIHVNDDVKKNAELLNVSNGVSDYDNPVFAPIRET
EYNYEINYGFHVTNWLTVRPNLQYITHPGGVDEVDNALVAGLKIQSTF

Specific function: Substrate-selective channel for a variety of different sugars. Could potentially facilitate the diffusion of diverse compounds, dependent on the presence of a hydroxyl group, but is presumably restricted to carbohydrates. Involved in the transport of gluc

COG id: COG3659

COG function: function code M; Carbohydrate-selective porin

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oprB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007049 [H]

Pfam domain/function: PF04966 OprB [H]

EC number: NA

Molecular weight: Translated: 49770; Mature: 49770

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNNNAQRIGQLSAVAAMMLAGSVHAADAFSSDSEWMTGDWGGERTKLIEQGIDIKMDY
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEECCCCCHHHHHHHCCCCEEEEE
VGEVGGNLHGGYNNDKTARYSDQFGLGVALDLQKLWGWDNTQAKIQLTNRNGENISNDRV
ECCCCCCCCCCCCCCCCEEECCCCCCEEEEEHHHHCCCCCCEEEEEEECCCCCCCCCCCC
GDPRAGTLSSSQEVYGRGHMVRLTQLWIKHQFFDNKLDVKAGYFGEGEDFNTFPCEFQNL
CCCCCCCCCCCHHHHCCCCEEEHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCHH
AFCGSQVGNWATNIWYNWPVSQAAIRVKYNINDELYAQIGAYNQNPSQLEHGNGFKLSGS
HHHHHHHCCEEEEEEEECCCCCEEEEEEECCCHHHHHEECCCCCCHHHCCCCCCEEEECC
GTKGTVLPVELVWSPNPNGLPGEYRVGYYKSTADADDVREDVNGFDAATTGDAYRTHSSK
CCCCEEEEEEEEECCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCCHHCCCCCC
HGYWFVAQQQLTSHNGDKSRGLSIAANATFHDKDTNFIDNYQSVMFVYKGPFDARPKDDF
CCEEEEEEHHHHCCCCCCCCCEEEEECCEEECCCCCHHHCCEEEEEEEECCCCCCCCCCC
GIGAARIHVNDDVKKNAELLNVSNGVSDYDNPVFAPIRETEYNYEINYGFHVTNWLTVRP
CCEEEEEEECCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCEEEEECEEEEEEEEECC
NLQYITHPGGVDEVDNALVAGLKIQSTF
CCEEEECCCCCCHHHHHEEECEEEEECC
>Mature Secondary Structure
MKKNNNAQRIGQLSAVAAMMLAGSVHAADAFSSDSEWMTGDWGGERTKLIEQGIDIKMDY
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEECCCCCHHHHHHHCCCCEEEEE
VGEVGGNLHGGYNNDKTARYSDQFGLGVALDLQKLWGWDNTQAKIQLTNRNGENISNDRV
ECCCCCCCCCCCCCCCCEEECCCCCCEEEEEHHHHCCCCCCEEEEEEECCCCCCCCCCCC
GDPRAGTLSSSQEVYGRGHMVRLTQLWIKHQFFDNKLDVKAGYFGEGEDFNTFPCEFQNL
CCCCCCCCCCCHHHHCCCCEEEHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCHH
AFCGSQVGNWATNIWYNWPVSQAAIRVKYNINDELYAQIGAYNQNPSQLEHGNGFKLSGS
HHHHHHHCCEEEEEEEECCCCCEEEEEEECCCHHHHHEECCCCCCHHHCCCCCCEEEECC
GTKGTVLPVELVWSPNPNGLPGEYRVGYYKSTADADDVREDVNGFDAATTGDAYRTHSSK
CCCCEEEEEEEEECCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCCHHCCCCCC
HGYWFVAQQQLTSHNGDKSRGLSIAANATFHDKDTNFIDNYQSVMFVYKGPFDARPKDDF
CCEEEEEEHHHHCCCCCCCCCEEEEECCEEECCCCCHHHCCEEEEEEEECCCCCCCCCCC
GIGAARIHVNDDVKKNAELLNVSNGVSDYDNPVFAPIRETEYNYEINYGFHVTNWLTVRP
CCEEEEEEECCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCEEEEECEEEEEEEEECC
NLQYITHPGGVDEVDNALVAGLKIQSTF
CCEEEECCCCCCHHHHHEEECEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8125108; 10984043; 2450582; 8132494; 7768797 [H]