Click here to switch to the map view.

The map label for this gene is pyrG [H]

Identifier: 77460532

GI number: 77460532

Start: 4868219

End: 4868926

Strand: Direct

Name: pyrG [H]

Synonym: Pfl01_4311

Alternate gene names: 77460532

Gene position: 4868219-4868926 (Clockwise)

Preceding gene: 77460530

Following gene: 77460533

Centisome position: 75.61

GC content: 62.15

Gene sequence:

>708_bases
ATGGAATCCAGAGCCCTGCGCATCGCCCTGATCGGTGACTTCGACCCGCAAGTTACTGCCCACCAAGCCATCCCGGTCGC
CCTCGGAATGGCGGCGGAACACCTTCGTTGTCCGGTCGATTTCGAATGGTTGGCCACCGACCGAATCCTGCCCGAGACAC
CGCTGGAACCTTTCGACGGCTTCTGGTGTGTCCCGGCCAGCCCTTATATAAGCGAAGTCGGTGCCTTGCGAGCCATCCGC
TTTGCCCGCGAGCGGCAGCGCCCTTTCCTCGGCACCTGCGGCGGTTTTCAACATGCCGTGCTGGAGTTTTCCCGCCACGT
GCTGGGCTGGACCGATGCCGAGCACGGCGAAACCTCGCCAGACGCCAGCCGCGCGGTACTCACGCCGCTGACCTGCTCGC
TGGTGGAAGCGGTGGACAGCATTCATCTGGTGCACGGTTCGTTGATCGCCAGTGCGTACGAAACGTCGGAAATTCGTGAA
GGCTATCGCTGCCGCTACGGTGTGAATCCGCAATTCGAACGGGAGTTGCTGACCCATGACCTGCACGCCGTGGGTCACGA
TTCGTCAGGCGACTTGCGCGCCATTGAACTGAAAAACCATGTGTTCTTCGTCGCCACACTGTTCCAGCCGGAACGCGCAG
CGCTCAAGGGGCAATTGCCGCCACTGGTGCGGGCGTTTGTCGAAGCCTGTGTCGAGGCGCGGGCATGA

Upstream 100 bases:

>100_bases
ATTGCGTGGTTGCATTGATCACTTGGGCAAACGCCGATTTAGAGTGCGTGAACGCCAATCTATAGTGAGCTTCATCCCTC
AACAAGCACAGTGAGTACTC

Downstream 100 bases:

>100_bases
TCGCCGAAACACCGAAAGCGCCGTACTACGCAGTGATCTTCACTTCAAACCGCACCGATGGTGATCAGGGCTACGCTGAA
GCCGCTGAACGCATGCTGGA

Product: hypothetical protein

Products: NA

Alternate protein names: CTP synthetase; UTP--ammonia ligase [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MESRALRIALIGDFDPQVTAHQAIPVALGMAAEHLRCPVDFEWLATDRILPETPLEPFDGFWCVPASPYISEVGALRAIR
FARERQRPFLGTCGGFQHAVLEFSRHVLGWTDAEHGETSPDASRAVLTPLTCSLVEAVDSIHLVHGSLIASAYETSEIRE
GYRCRYGVNPQFERELLTHDLHAVGHDSSGDLRAIELKNHVFFVATLFQPERAALKGQLPPLVRAFVEACVEARA

Sequences:

>Translated_235_residues
MESRALRIALIGDFDPQVTAHQAIPVALGMAAEHLRCPVDFEWLATDRILPETPLEPFDGFWCVPASPYISEVGALRAIR
FARERQRPFLGTCGGFQHAVLEFSRHVLGWTDAEHGETSPDASRAVLTPLTCSLVEAVDSIHLVHGSLIASAYETSEIRE
GYRCRYGVNPQFERELLTHDLHAVGHDSSGDLRAIELKNHVFFVATLFQPERAALKGQLPPLVRAFVEACVEARA
>Mature_235_residues
MESRALRIALIGDFDPQVTAHQAIPVALGMAAEHLRCPVDFEWLATDRILPETPLEPFDGFWCVPASPYISEVGALRAIR
FARERQRPFLGTCGGFQHAVLEFSRHVLGWTDAEHGETSPDASRAVLTPLTCSLVEAVDSIHLVHGSLIASAYETSEIRE
GYRCRYGVNPQFERELLTHDLHAVGHDSSGDLRAIELKNHVFFVATLFQPERAALKGQLPPLVRAFVEACVEARA

Specific function: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen [H]

COG id: COG0504

COG function: function code F; CTP synthase (UTP-ammonia lyase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI148491070, Length=150, Percent_Identity=34.6666666666667, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI28559085, Length=154, Percent_Identity=34.4155844155844, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI28559083, Length=154, Percent_Identity=34.4155844155844, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI221316689, Length=154, Percent_Identity=34.4155844155844, Blast_Score=82, Evalue=3e-16,
Organism=Escherichia coli, GI1789142, Length=251, Percent_Identity=26.6932270916335, Blast_Score=77, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319432, Length=238, Percent_Identity=28.1512605042017, Blast_Score=84, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21357815, Length=150, Percent_Identity=34, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24664469, Length=150, Percent_Identity=34, Blast_Score=78, Evalue=4e-15,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004468
- InterPro:   IPR017456
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF06418 CTP_synth_N; PF00117 GATase [H]

EC number: =6.3.4.2 [H]

Molecular weight: Translated: 26022; Mature: 26022

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESRALRIALIGDFDPQVTAHQAIPVALGMAAEHLRCPVDFEWLATDRILPETPLEPFDG
CCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCC
FWCVPASPYISEVGALRAIRFARERQRPFLGTCGGFQHAVLEFSRHVLGWTDAEHGETSP
EEECCCCHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHCCCCCCCCCCCC
DASRAVLTPLTCSLVEAVDSIHLVHGSLIASAYETSEIREGYRCRYGVNPQFERELLTHD
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHH
LHAVGHDSSGDLRAIELKNHVFFVATLFQPERAALKGQLPPLVRAFVEACVEARA
HHHCCCCCCCCEEEEEECCCEEEEEEECCCHHHHHCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MESRALRIALIGDFDPQVTAHQAIPVALGMAAEHLRCPVDFEWLATDRILPETPLEPFDG
CCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCC
FWCVPASPYISEVGALRAIRFARERQRPFLGTCGGFQHAVLEFSRHVLGWTDAEHGETSP
EEECCCCHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHCCCCCCCCCCCC
DASRAVLTPLTCSLVEAVDSIHLVHGSLIASAYETSEIREGYRCRYGVNPQFERELLTHD
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHH
LHAVGHDSSGDLRAIELKNHVFFVATLFQPERAALKGQLPPLVRAFVEACVEARA
HHHCCCCCCCCEEEEEECCCEEEEEEECCCHHHHHCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA