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The map label for this gene is 77460484

Identifier: 77460484

GI number: 77460484

Start: 4810428

End: 4812062

Strand: Reverse

Name: 77460484

Synonym: Pfl01_4263

Alternate gene names: NA

Gene position: 4812062-4810428 (Counterclockwise)

Preceding gene: 77460485

Following gene: 77460482

Centisome position: 74.74

GC content: 60.24

Gene sequence:

>1635_bases
ATGAGCAGCGATCAATTCGATGCCGATGTGGTGATCATCGGTTCTGGTGTCATGGGCGGTCTGATCGCCACGGGCCTGGC
CAAAGCAAACAAGTCGGTGATCGTGCTCGAGGCCGGGCCTCGGGTGAATCGTCGTGATGTGGTGGAAACGTTCCGCAATG
CGCCGGTGAAACTCTCGCTGGCCAATGCCAAGCTGCAGGGCGCCGGGTCGCCTTATCCGAGCCTGCCCCACGCGCCGTCG
ACCTACGGCGACTATTTGCAGCAGGTAGGGCCGGTGAAATACAACACCTCGTATCTGCGTGTAGTGGGTGGGACCACCTG
GCATTTCGGTTCCTCGCTGTGGCGCATGCTGCCCAATGATTTTCGTCTCAAGTCGCTGTATGGCCGTGGTCGCGACTGGC
CGATCAGTTATGACGAACTCGAACCGTACTACGCTCGGGCTGAAATCGAACTGGGCGTTTCCGGTGTCGACGGCCAGGAC
GAAAGCGGGCAGGGCGGGGACGCCTATCCGCCGCGCTCGATTCCCTATCCGATGGAGGGCCTGAAACCGAGCTACATGTT
CAAGCGCCTTTCCGAATTGCTCAGCAAGGGTGGGTATAACCCGATCCTCGAGCCGAATGGCCGGGCGACCCGCCCCTATG
GCAAGCGGCCTCCCTGCGCTGGCAACAACAACTGCAATCCGGTGTGTCCGATTGCCGCCAAGTACGACGGTTCGATGCAC
ATCGATGAGGCCGAGCGCCATGGCGCCAAGGTGCTGGACAACTCTGTCGTCTACAAGATCGAGGCGGGCGACGACGGCAA
GATCACCGCGATCTGGTACATGCGCCCCGACAAGTCCAAACACAAACTGACCGCCCGGGCCTTTGTACTGGCGGCGTACG
GTATCGAGTCGCCGAAGCTGCTGTTGATGTCGACCTCGGAAAAGTACCCGAACGGGATTGCCAACTCCTCGGATCAGGTC
GGGCGCAACCTGATGGACCACACCGGCATCAGCATGAACGTCATGACCAAGGAAGACATGTGGCCGGGCGAGGGGCCGAC
GCAATTGCTGGTCTATCTGAACAGCCGCGATGGCGCGTTTCGCAACGATTACCCGAGCTACAAGATCAAGGTGCGCAACA
CCGTGCCGACGTCGCAAATCACCTCGAACCTGATCGCCAAAGGTGTCCTGGGCTCGAAGCTCGATGAGCAGATCCGCCTG
CAATCGGCGCGCTCCCTGAACTGGGCTGTCGACTTCGAAACCCTGCCACTGCCGGAAAACCGGGTCACCCCGAGCAAGAC
CAAGTTCGACGCCATCGGTCTGCCGGTTCCCGAGATCTACTACAGCGTTCCCGACTACTGGCACGCCGGTAAAGAGAAGG
CGCTGGAAGACTTCAAACAGTTTGCGAAATTGCTCGACGCCGACATCGTCAGTACGGACACGGGCTTCCAGAACCGTCAG
CACATCATGGGCACCACCATCATGGGCGATGACCCGAAAGACTCGGTGGTGGACCGCGATTGCCGCAGTCACGACCATTC
CAACCTGTTCATCGCTGGCACGAGCGTCATGCCATCGTCCTCCTGCGTGAACCCGACGCTGACGGGTGCGGCGTTGAGTA
TTCGGATTGCCGATGTGTTGGTGGCGGAGGTCTGA

Upstream 100 bases:

>100_bases
TGATGTATCAGCCCACTCACGGCATTCTCATCATTCCAACCTACGGTGGCGGCCCGGATTCATGGGGTCCCAAACCATCA
GTCATTCAGGACTCGACAGT

Downstream 100 bases:

>100_bases
GAAGCGCCCTGAAGTACAAAGCCCCACGCAGAGGTGTCTGGTGGGGCTTTTTTGTGTCTTTCAATCTTGCAGGAGGAAGG
GCTAGAAAATTTCAGCTCCA

Product: glucose-methanol-choline oxidoreductase

Products: NA

Alternate protein names: GA 2-DH dehydrogenase subunit; GADH dehydrogenase subunit [H]

Number of amino acids: Translated: 544; Mature: 543

Protein sequence:

>544_residues
MSSDQFDADVVIIGSGVMGGLIATGLAKANKSVIVLEAGPRVNRRDVVETFRNAPVKLSLANAKLQGAGSPYPSLPHAPS
TYGDYLQQVGPVKYNTSYLRVVGGTTWHFGSSLWRMLPNDFRLKSLYGRGRDWPISYDELEPYYARAEIELGVSGVDGQD
ESGQGGDAYPPRSIPYPMEGLKPSYMFKRLSELLSKGGYNPILEPNGRATRPYGKRPPCAGNNNCNPVCPIAAKYDGSMH
IDEAERHGAKVLDNSVVYKIEAGDDGKITAIWYMRPDKSKHKLTARAFVLAAYGIESPKLLLMSTSEKYPNGIANSSDQV
GRNLMDHTGISMNVMTKEDMWPGEGPTQLLVYLNSRDGAFRNDYPSYKIKVRNTVPTSQITSNLIAKGVLGSKLDEQIRL
QSARSLNWAVDFETLPLPENRVTPSKTKFDAIGLPVPEIYYSVPDYWHAGKEKALEDFKQFAKLLDADIVSTDTGFQNRQ
HIMGTTIMGDDPKDSVVDRDCRSHDHSNLFIAGTSVMPSSSCVNPTLTGAALSIRIADVLVAEV

Sequences:

>Translated_544_residues
MSSDQFDADVVIIGSGVMGGLIATGLAKANKSVIVLEAGPRVNRRDVVETFRNAPVKLSLANAKLQGAGSPYPSLPHAPS
TYGDYLQQVGPVKYNTSYLRVVGGTTWHFGSSLWRMLPNDFRLKSLYGRGRDWPISYDELEPYYARAEIELGVSGVDGQD
ESGQGGDAYPPRSIPYPMEGLKPSYMFKRLSELLSKGGYNPILEPNGRATRPYGKRPPCAGNNNCNPVCPIAAKYDGSMH
IDEAERHGAKVLDNSVVYKIEAGDDGKITAIWYMRPDKSKHKLTARAFVLAAYGIESPKLLLMSTSEKYPNGIANSSDQV
GRNLMDHTGISMNVMTKEDMWPGEGPTQLLVYLNSRDGAFRNDYPSYKIKVRNTVPTSQITSNLIAKGVLGSKLDEQIRL
QSARSLNWAVDFETLPLPENRVTPSKTKFDAIGLPVPEIYYSVPDYWHAGKEKALEDFKQFAKLLDADIVSTDTGFQNRQ
HIMGTTIMGDDPKDSVVDRDCRSHDHSNLFIAGTSVMPSSSCVNPTLTGAALSIRIADVLVAEV
>Mature_543_residues
SSDQFDADVVIIGSGVMGGLIATGLAKANKSVIVLEAGPRVNRRDVVETFRNAPVKLSLANAKLQGAGSPYPSLPHAPST
YGDYLQQVGPVKYNTSYLRVVGGTTWHFGSSLWRMLPNDFRLKSLYGRGRDWPISYDELEPYYARAEIELGVSGVDGQDE
SGQGGDAYPPRSIPYPMEGLKPSYMFKRLSELLSKGGYNPILEPNGRATRPYGKRPPCAGNNNCNPVCPIAAKYDGSMHI
DEAERHGAKVLDNSVVYKIEAGDDGKITAIWYMRPDKSKHKLTARAFVLAAYGIESPKLLLMSTSEKYPNGIANSSDQVG
RNLMDHTGISMNVMTKEDMWPGEGPTQLLVYLNSRDGAFRNDYPSYKIKVRNTVPTSQITSNLIAKGVLGSKLDEQIRLQ
SARSLNWAVDFETLPLPENRVTPSKTKFDAIGLPVPEIYYSVPDYWHAGKEKALEDFKQFAKLLDADIVSTDTGFQNRQH
IMGTTIMGDDPKDSVVDRDCRSHDHSNLFIAGTSVMPSSSCVNPTLTGAALSIRIADVLVAEV

Specific function: Part of the heterotrimer that catalyzes the conversion of D-gluconate to 2-dehydro-D-gluconate. This subunit functions as the dehydrogenase [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.3 [H]

Molecular weight: Translated: 59667; Mature: 59536

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDQFDADVVIIGSGVMGGLIATGLAKANKSVIVLEAGPRVNRRDVVETFRNAPVKLSL
CCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEE
ANAKLQGAGSPYPSLPHAPSTYGDYLQQVGPVKYNTSYLRVVGGTTWHFGSSLWRMLPND
ECCEECCCCCCCCCCCCCCCHHHHHHHHCCCCEECCCEEEEECCCEEHHHHHHHHHCCCC
FRLKSLYGRGRDWPISYDELEPYYARAEIELGVSGVDGQDESGQGGDAYPPRSIPYPMEG
CEEHHHHCCCCCCCCCHHHCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
LKPSYMFKRLSELLSKGGYNPILEPNGRATRPYGKRPPCAGNNNCNPVCPIAAKYDGSMH
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCEEEECCCCEE
IDEAERHGAKVLDNSVVYKIEAGDDGKITAIWYMRPDKSKHKLTARAFVLAAYGIESPKL
CCHHHHCCCEEECCCEEEEEECCCCCCEEEEEEECCCCCCHHHHHHEEEEEEECCCCCEE
LLMSTSEKYPNGIANSSDQVGRNLMDHTGISMNVMTKEDMWPGEGPTQLLVYLNSRDGAF
EEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCC
RNDYPSYKIKVRNTVPTSQITSNLIAKGVLGSKLDEQIRLQSARSLNWAVDFETLPLPEN
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCC
RVTPSKTKFDAIGLPVPEIYYSVPDYWHAGKEKALEDFKQFAKLLDADIVSTDTGFQNRQ
CCCCCCCCCCCCCCCHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHCCHHEECCCCCCCCC
HIMGTTIMGDDPKDSVVDRDCRSHDHSNLFIAGTSVMPSSSCVNPTLTGAALSIRIADVL
EEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEEHHH
VAEV
EECC
>Mature Secondary Structure 
SSDQFDADVVIIGSGVMGGLIATGLAKANKSVIVLEAGPRVNRRDVVETFRNAPVKLSL
CCCCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEE
ANAKLQGAGSPYPSLPHAPSTYGDYLQQVGPVKYNTSYLRVVGGTTWHFGSSLWRMLPND
ECCEECCCCCCCCCCCCCCCHHHHHHHHCCCCEECCCEEEEECCCEEHHHHHHHHHCCCC
FRLKSLYGRGRDWPISYDELEPYYARAEIELGVSGVDGQDESGQGGDAYPPRSIPYPMEG
CEEHHHHCCCCCCCCCHHHCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
LKPSYMFKRLSELLSKGGYNPILEPNGRATRPYGKRPPCAGNNNCNPVCPIAAKYDGSMH
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCEEEECCCCEE
IDEAERHGAKVLDNSVVYKIEAGDDGKITAIWYMRPDKSKHKLTARAFVLAAYGIESPKL
CCHHHHCCCEEECCCEEEEEECCCCCCEEEEEEECCCCCCHHHHHHEEEEEEECCCCCEE
LLMSTSEKYPNGIANSSDQVGRNLMDHTGISMNVMTKEDMWPGEGPTQLLVYLNSRDGAF
EEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCC
RNDYPSYKIKVRNTVPTSQITSNLIAKGVLGSKLDEQIRLQSARSLNWAVDFETLPLPEN
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCC
RVTPSKTKFDAIGLPVPEIYYSVPDYWHAGKEKALEDFKQFAKLLDADIVSTDTGFQNRQ
CCCCCCCCCCCCCCCHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHCCHHEECCCCCCCCC
HIMGTTIMGDDPKDSVVDRDCRSHDHSNLFIAGTSVMPSSSCVNPTLTGAALSIRIADVL
EEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEEHHH
VAEV
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9352901 [H]