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The map label for this gene is 77460408

Identifier: 77460408

GI number: 77460408

Start: 4724764

End: 4725390

Strand: Direct

Name: 77460408

Synonym: Pfl01_4187

Alternate gene names: NA

Gene position: 4724764-4725390 (Clockwise)

Preceding gene: 77460406

Following gene: 77460409

Centisome position: 73.38

GC content: 59.33

Gene sequence:

>627_bases
ATGACGCTTCGCCTCTTTTTCCATAGTGATGACCTCAAGGCCAATGTGGAAGTCCTCGACTGCACGCCCCAAGAGAACGA
ATTCGCCGTTGTGTTGCGCGCCACGCTTTTTCATCCCCAGGGCGGTGGCCAACCCTGTGACACCGGCTGGATTGGCGACA
GCCAAGTGCTGCGGGTCGTCCAGGAACCGGACCGGATCATTCATTTCGTCGATCAACCGATGCCACTGGGCATGACCCAG
ATTCGCGTCGACGAAGAACGCCGCCGCTTCAACACCCGCATGCACTCTGCCGGGCATTTGATCGGCCACTTTGTCCAGGC
CATGGGCTGGATGCCGATCAAGGCACACCACTGGCCGGACGAAGGCCGGGTGCAATTCAAACCCGGTGATTCGGCCCAGG
AAGTCGATGCACAAATCGTTCAATACGGCATCGGCCAATGGATCGAGCACGATCTGCCACGCCTGACGTCTCTGCGCGAA
GGCGCGCGGGAAATCGGTTTCGGTGAACTGCCAGCCTATGGCTGCGGTGGCACCCATGTACGCAGCCTGAAGGATCTGGG
CACAGTCACGATCGCGTCCCTTTCGCAGAAGAAAGGCACGTTGTCCGTCCACTACAGCGTGGATTGA

Upstream 100 bases:

>100_bases
TTATGCTCACAGCGCAACAGTCCTTTGATGTTTGAACGGATTATCACGTTATTGCACGATTCATATAATTAAAAAAGAAA
CTTTAATAAGGGCATGGAAT

Downstream 100 bases:

>100_bases
GGATTTCGGGCGCTGCCAGATGCAGCGTCCGACGCCGGGGGAACCGCATTCGCCGGTTCCGTTGACTATTCGATAGATGG
ACCTGACACCATGATGCTTG

Product: metal-dependent hydrolase

Products: AMP; diphosphate; L-alanyl-tRNA(Ala)

Alternate protein names: Metal-Dependent Hydrolase; Alanyl-TRNA Synthetase; Alanyl-TRNA Synthetase-Related Protein; Alanyl-TRNA Synthetase Domain-Containing Protein; Alanyl-TRNA Synthetase Class IIc-Like Protein; Alanyl-TRNA Synthetase Truncated; Threonyl/Alanyl TRNA Synthetase SAD Protein; Alanyl-TRNA Synthetase Domain Protein; Metal-Dependent Hydrolases

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MTLRLFFHSDDLKANVEVLDCTPQENEFAVVLRATLFHPQGGGQPCDTGWIGDSQVLRVVQEPDRIIHFVDQPMPLGMTQ
IRVDEERRRFNTRMHSAGHLIGHFVQAMGWMPIKAHHWPDEGRVQFKPGDSAQEVDAQIVQYGIGQWIEHDLPRLTSLRE
GAREIGFGELPAYGCGGTHVRSLKDLGTVTIASLSQKKGTLSVHYSVD

Sequences:

>Translated_208_residues
MTLRLFFHSDDLKANVEVLDCTPQENEFAVVLRATLFHPQGGGQPCDTGWIGDSQVLRVVQEPDRIIHFVDQPMPLGMTQ
IRVDEERRRFNTRMHSAGHLIGHFVQAMGWMPIKAHHWPDEGRVQFKPGDSAQEVDAQIVQYGIGQWIEHDLPRLTSLRE
GAREIGFGELPAYGCGGTHVRSLKDLGTVTIASLSQKKGTLSVHYSVD
>Mature_207_residues
TLRLFFHSDDLKANVEVLDCTPQENEFAVVLRATLFHPQGGGQPCDTGWIGDSQVLRVVQEPDRIIHFVDQPMPLGMTQI
RVDEERRRFNTRMHSAGHLIGHFVQAMGWMPIKAHHWPDEGRVQFKPGDSAQEVDAQIVQYGIGQWIEHDLPRLTSLREG
AREIGFGELPAYGCGGTHVRSLKDLGTVTIASLSQKKGTLSVHYSVD

Specific function: Unknown

COG id: COG2872

COG function: function code R; Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI13376886, Length=231, Percent_Identity=29.004329004329, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI217416402, Length=231, Percent_Identity=29.004329004329, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 6.1.1.7

Molecular weight: Translated: 23320; Mature: 23189

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRLFFHSDDLKANVEVLDCTPQENEFAVVLRATLFHPQGGGQPCDTGWIGDSQVLRVV
CEEEEEEECCCCCCCEEEEECCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHH
QEPDRIIHFVDQPMPLGMTQIRVDEERRRFNTRMHSAGHLIGHFVQAMGWMPIKAHHWPD
HCCCCEEHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCC
EGRVQFKPGDSAQEVDAQIVQYGIGQWIEHDLPRLTSLREGAREIGFGELPAYGCGGTHV
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
RSLKDLGTVTIASLSQKKGTLSVHYSVD
HHHHHCCCEEEEECCCCCCEEEEEEECC
>Mature Secondary Structure 
TLRLFFHSDDLKANVEVLDCTPQENEFAVVLRATLFHPQGGGQPCDTGWIGDSQVLRVV
EEEEEEECCCCCCCEEEEECCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHH
QEPDRIIHFVDQPMPLGMTQIRVDEERRRFNTRMHSAGHLIGHFVQAMGWMPIKAHHWPD
HCCCCEEHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCC
EGRVQFKPGDSAQEVDAQIVQYGIGQWIEHDLPRLTSLREGAREIGFGELPAYGCGGTHV
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
RSLKDLGTVTIASLSQKKGTLSVHYSVD
HHHHHCCCEEEEECCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-alanine; tRNA(Ala)

Specific reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA