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The map label for this gene is ltrA [H]

Identifier: 77460407

GI number: 77460407

Start: 4723678

End: 4724673

Strand: Reverse

Name: ltrA [H]

Synonym: Pfl01_4186

Alternate gene names: 77460407

Gene position: 4724673-4723678 (Counterclockwise)

Preceding gene: 77460413

Following gene: 77460404

Centisome position: 73.38

GC content: 60.84

Gene sequence:

>996_bases
GTGAGCATAAATCTTCCACTGCCGCTGCTCGGTGAAATGGCGATTTTCGTCAAGGTCGTAGAGACCGGAAGCTTCTCCGA
AGCCGCTCGCCAATTGGGCTCATCGCCATCGGCAGTCAGCCGCAGCATTTCCCGGCTGGAGAAGGCGCTGGCCACGCGGC
TGCTGCAACGCACCACGCGCAAACTGCGCTTGAGCGATGGCGGGGAAGAGGTGTTCAAACGCTGTCAGGAAATGGTCAGC
GCGGCGAAGTCGGTAATGGAGATCAGCGGCCAGTTCACCCACGAAGCCGAGGGGCTGGTGCGGGTCAGCGTGCCGAAAGC
GGTTGGGCGCTTCGTGATTCATCCGCACATGCCGGAGTTTCTGCGGCGCTATCCGAAGGTCGACGTGGAGCTGTTGCTGG
AGGACCGCCAGGTCGATCTTATCGACGACCATGTCGACCTGGCCATTCGCATCACGGACCGTCCACCGGCTGGACTGGTG
GGACGACAACTGTTGACCATCGACCATTTGCTCTGCGCGACGCCGCAGTATCTGGCCGAACACGGGACGCCGACTCATCC
CCATGACTTGCTTAACCACAGTTGCATTTACCTGGGCGAAACCCCGAGCGATGCGCGCTGGAAATTCAAGAAAGGCACGA
AAGCCGTCACTGTCGGCGTGCGCGGGCGGTATGCCGCCAATCACACCGGCGTGCGTCTGGGTGCGGTGTTGCAGCACATC
GGTATCGGCAGCCTGCCGTATTTCACCGCGCGTTATGCGCTTGAGCAGGGGCTGATCGTGCAGGTGCTGCCGGAATGGAC
ATTCCTGGCCTCGTACCACGGCGGATTGTGGTTGCTGCACTCGCCGACGCGCTATCTGCCGCCGAAGCTGCGGGTGTTCA
TTGACTATCTGGTGGAGTGCCTGGAGAAAGAGCCGACCCTGAGCAAACCGGGAAAGTCTGGCGGTGCAAAACCGTTGGCC
GAGTACGAATTGCCCGAGAGTGAAGGGTTGCTTTGA

Upstream 100 bases:

>100_bases
GAAGCGTCATATTCCATGCCCTTATTAAAGTTTCTTTTTTAATTATATGAATCGTGCAATAACGTGATAATCCGTTCAAA
CATCAAAGGACTGTTGCGCT

Downstream 100 bases:

>100_bases
CCTGATAAAAAAAGGCCCGCATGGATCACCGTGCGGGCCTTTTTTTATCGGGCGAAAATCAGTGCTTGCTGTCCTGGGCG
GACATCGCCAGCAGCTGTTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSINLPLPLLGEMAIFVKVVETGSFSEAARQLGSSPSAVSRSISRLEKALATRLLQRTTRKLRLSDGGEEVFKRCQEMVS
AAKSVMEISGQFTHEAEGLVRVSVPKAVGRFVIHPHMPEFLRRYPKVDVELLLEDRQVDLIDDHVDLAIRITDRPPAGLV
GRQLLTIDHLLCATPQYLAEHGTPTHPHDLLNHSCIYLGETPSDARWKFKKGTKAVTVGVRGRYAANHTGVRLGAVLQHI
GIGSLPYFTARYALEQGLIVQVLPEWTFLASYHGGLWLLHSPTRYLPPKLRVFIDYLVECLEKEPTLSKPGKSGGAKPLA
EYELPESEGLL

Sequences:

>Translated_331_residues
MSINLPLPLLGEMAIFVKVVETGSFSEAARQLGSSPSAVSRSISRLEKALATRLLQRTTRKLRLSDGGEEVFKRCQEMVS
AAKSVMEISGQFTHEAEGLVRVSVPKAVGRFVIHPHMPEFLRRYPKVDVELLLEDRQVDLIDDHVDLAIRITDRPPAGLV
GRQLLTIDHLLCATPQYLAEHGTPTHPHDLLNHSCIYLGETPSDARWKFKKGTKAVTVGVRGRYAANHTGVRLGAVLQHI
GIGSLPYFTARYALEQGLIVQVLPEWTFLASYHGGLWLLHSPTRYLPPKLRVFIDYLVECLEKEPTLSKPGKSGGAKPLA
EYELPESEGLL
>Mature_330_residues
SINLPLPLLGEMAIFVKVVETGSFSEAARQLGSSPSAVSRSISRLEKALATRLLQRTTRKLRLSDGGEEVFKRCQEMVSA
AKSVMEISGQFTHEAEGLVRVSVPKAVGRFVIHPHMPEFLRRYPKVDVELLLEDRQVDLIDDHVDLAIRITDRPPAGLVG
RQLLTIDHLLCATPQYLAEHGTPTHPHDLLNHSCIYLGETPSDARWKFKKGTKAVTVGVRGRYAANHTGVRLGAVLQHIG
IGSLPYFTARYALEQGLIVQVLPEWTFLASYHGGLWLLHSPTRYLPPKLRVFIDYLVECLEKEPTLSKPGKSGGAKPLAE
YELPESEGLL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=306, Percent_Identity=31.0457516339869, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI87081978, Length=304, Percent_Identity=29.2763157894737, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1787128, Length=296, Percent_Identity=29.0540540540541, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI145693193, Length=298, Percent_Identity=30.8724832214765, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1786401, Length=304, Percent_Identity=32.5657894736842, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1789639, Length=295, Percent_Identity=28.4745762711864, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787589, Length=292, Percent_Identity=25.3424657534247, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788706, Length=295, Percent_Identity=25.0847457627119, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788748, Length=127, Percent_Identity=34.6456692913386, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789173, Length=237, Percent_Identity=28.2700421940928, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790011, Length=259, Percent_Identity=23.1660231660232, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI157672245, Length=140, Percent_Identity=30.7142857142857, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788481, Length=310, Percent_Identity=24.1935483870968, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36707; Mature: 36576

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSINLPLPLLGEMAIFVKVVETGSFSEAARQLGSSPSAVSRSISRLEKALATRLLQRTTR
CCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KLRLSDGGEEVFKRCQEMVSAAKSVMEISGQFTHEAEGLVRVSVPKAVGRFVIHPHMPEF
HEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHCCEEECCCCHHH
LRRYPKVDVELLLEDRQVDLIDDHVDLAIRITDRPPAGLVGRQLLTIDHLLCATPQYLAE
HHHCCCCCEEEEEECCCCEEEECCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHH
HGTPTHPHDLLNHSCIYLGETPSDARWKFKKGTKAVTVGVRGRYAANHTGVRLGAVLQHI
CCCCCCHHHHHCCCEEEECCCCCCCCEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHC
GIGSLPYFTARYALEQGLIVQVLPEWTFLASYHGGLWLLHSPTRYLPPKLRVFIDYLVEC
CCCCCHHHHHHHHHHCCCEEEECCCHHEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHH
LEKEPTLSKPGKSGGAKPLAEYELPESEGLL
HHCCCCCCCCCCCCCCCCCHHCCCCCCCCCC
>Mature Secondary Structure 
SINLPLPLLGEMAIFVKVVETGSFSEAARQLGSSPSAVSRSISRLEKALATRLLQRTTR
CCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KLRLSDGGEEVFKRCQEMVSAAKSVMEISGQFTHEAEGLVRVSVPKAVGRFVIHPHMPEF
HEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHCCEEECCCCHHH
LRRYPKVDVELLLEDRQVDLIDDHVDLAIRITDRPPAGLVGRQLLTIDHLLCATPQYLAE
HHHCCCCCEEEEEECCCCEEEECCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHH
HGTPTHPHDLLNHSCIYLGETPSDARWKFKKGTKAVTVGVRGRYAANHTGVRLGAVLQHI
CCCCCCHHHHHCCCEEEECCCCCCCCEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHC
GIGSLPYFTARYALEQGLIVQVLPEWTFLASYHGGLWLLHSPTRYLPPKLRVFIDYLVEC
CCCCCHHHHHHHHHHCCCEEEECCCHHEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHH
LEKEPTLSKPGKSGGAKPLAEYELPESEGLL
HHCCCCCCCCCCCCCCCCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]