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The map label for this gene is iorB [H]

Identifier: 77460390

GI number: 77460390

Start: 4706684

End: 4709005

Strand: Reverse

Name: iorB [H]

Synonym: Pfl01_4169

Alternate gene names: 77460390

Gene position: 4709005-4706684 (Counterclockwise)

Preceding gene: 77460391

Following gene: 77460389

Centisome position: 73.14

GC content: 63.57

Gene sequence:

>2322_bases
ATGAGCCGTCTACCGAACGATTTCGCCCTGAGCAACCTGAGCCGTCGGGGCTTCCTCAAGGGCGTCGGCGCCACCGGGGC
GTTGGTGCTGGCGGCGAGCTGGGGCTGGCAGGGTGCGCTGGCCGAAGACAAACCGAAGCAGTTCGGCGCCGACGGCATGC
CCAACGGCTGGATCGACGATCCGAAGGTCTACGTCAGCATTGCCGCCGACGGCACGGTGACCGTGGTCTGTAACCGTTCG
GAAATGGGCCAGGGCGTGCGCACCAGCCTGACCATGGTGATTGCCGATGAGCTGGAAGCCGACTGGGCGCACGTCAAGGT
TCAGCAGGCGCCGGGTGATGAAGTGCGCTTCGGCAACCAGGACACTGACGGCTCGCGCAGCATGCGTCACTGGTACGAAC
CGATGCGCCGTTGCGGCGCCGCCGCCCGGATCATGCTGGAACAAGCGGCCGCCGCCCAGTGGAAGGTGCCGGTCGGCGAA
TGCCGCGCGCAACTGCATAAAGTCATTCACACACCGTCCGGACGCGAGCTGGGTTACGGTGAGCTGGCCGCTGCGGCCAG
TGCGCTGACGGTGCCGGCCCGTGACAGCCTGCGGCTCAAGCAGCCGTCGGAATTCCGCTATATCGGCAAGCAAGGTACCA
AAGCCATCGACGGTGCCGACATCGTCAATGGTCGCGCGGTTTACGGGGCTGACGTGCATTTCGACGGCATGCTGTTTGCG
GTGATTGCGCGTCCGGCGGTGTACGGTGGCAAGGTCAAATCGGTGGACGACAGCGCCGCGCTGAAAGTGCCGGGCGTCCT
CAAAGTCATCCAGATCGAGCCTCGGCCATTGCCTTCCGAATTCCAGCCGTTAGGCGGCGTGGCCGTGGTGGCCAGCAACA
CCTGGGCGGCATTGAAGGGCCGTGAAGCGCTGAAGATCGAGTGGGACGATGGCCCGAACGCCACTTATGACTCGGTCGCC
TATCGCAAAGAGATCGAAGCCGCTTCGCTGAAACCGGGCAAAGTGGTGCGCAATACCGGCGACATCGACAAGGCCATCGG
CAGCGCCGCCAGCACGCTGGAAGCCTCTTATTACTTGCCGCATCTGGCCCAGGCACCGATGGAGCCGATGGTCGCCATCG
CCCGTTACAAGGATGACACCTGCGAGGCCTGGGCACCGAGCCAGGCGCCGCAGGTCACCCGCGAGCGGATCGCCGAACGC
CTGGGGCTGCCGTTCGATAACGTCACCTTCAATGTCACGCTGTTGGGCGGTGGTTTCGGGCGCAAGTCCAAACCGGACTT
CGTCGTTGAAGCGGCCGTGCTCGCCAAGGAATTCCCTGGCAAGGCAGTGCGCGTGCAATGGACCCGGGAAGACGATATCC
ACAACTCGTATTTCCACACTGTGTCCGCCGAATACCTCAAGGCCGGCGTCGGCAAGGACGGCTTGCCGTCTGCCTGGTTG
CACCGCACGGTGGCGCCGAGCATCACCGCGCTGTTTGCGCCGGGCATGAACCACGAGGCCGCATTCGAACTGGGCATGGG
CTTTACCAACATGGCCTACGCGATTCCCAACGTGCGCCTGGAAAACCCTGAAGCCACGGTTCATACGCGGGTGGGCTGGT
ATCGCTCGGTGTCGAATATTCCCCATGGTTTTGCGATCCAGAGTTTCGTCGATGAACTGGCGCACAAAGCCAAGGAAGAT
CCGCTCAAGTACCAGATCAAATTGCTCGGCCCGGATCGGCAGATCGACCCACGCACGCTCAGTGAAGAATGGAATTACGG
CGAATCCCCCGAGCGTTATCCGATCGACACCGGGCGCATGCGCACCGTGCTGGAAACGGCAGCCAAGGCGGCGGGTTGGG
GTCGTCAACTGCCCAAGGGTCGTGGTCTCGGATTGGCCGTGCATTACAGCTTCGTCACCTACGTGGCGGCGGTGATCGAA
GTCGAGGTCAAGGACGACGGCACGCTGATCGTGCACAAGGCCGATATCGCCGTGGATTGCGGCCCGCAGATCAACCCCGA
GCGCATCCGTTCGCAGTTCGAAGGCGCTTGTGTGATGGGCCTGGGCAACGCCGTGTGGGGCGAAATCAGCTTCAAGGACG
GCAAGGTGCAGCAAGACAACTTCCATATGTATGAAGTGGCGCGCATGTCGCTGGCGCCGAAGGAAGTTGCGGTGCATCTG
GTGACGCCGCCGGGCGAGGTGCCGTTGGGCGGTGTCGGTGAGCCGGGCGTGCCGCCGATTGCGCCGGCGCTGTGCAACGC
GATCTTCGCCGCCACCGGTCAGCGCATTCGCAACCTGCCGGTGCGCTACCAGTTGCAGGGCTGGCAAAAGGCGCAAGCGT
GA

Upstream 100 bases:

>100_bases
TCGAAGAAGCGATGGTCGGCAACATCTGCCGCTGCGGCACCTACAACCGGATCAAGACCGCGATCCGTCAGGCATCCACT
CACCTGAAGGAGGCCAAGGC

Downstream 100 bases:

>100_bases
TGGACAGCGCCGATCTGAATGTCCTGCGCAGTGTGCTCGAATGGCGTCGCGCCGGGCAGCGAGTGATGTTGTTCAGCGTG
GTGCAGACCTGGGGCACCGC

Product: twin-arginine translocation pathway signal protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 773; Mature: 772

Protein sequence:

>773_residues
MSRLPNDFALSNLSRRGFLKGVGATGALVLAASWGWQGALAEDKPKQFGADGMPNGWIDDPKVYVSIAADGTVTVVCNRS
EMGQGVRTSLTMVIADELEADWAHVKVQQAPGDEVRFGNQDTDGSRSMRHWYEPMRRCGAAARIMLEQAAAAQWKVPVGE
CRAQLHKVIHTPSGRELGYGELAAAASALTVPARDSLRLKQPSEFRYIGKQGTKAIDGADIVNGRAVYGADVHFDGMLFA
VIARPAVYGGKVKSVDDSAALKVPGVLKVIQIEPRPLPSEFQPLGGVAVVASNTWAALKGREALKIEWDDGPNATYDSVA
YRKEIEAASLKPGKVVRNTGDIDKAIGSAASTLEASYYLPHLAQAPMEPMVAIARYKDDTCEAWAPSQAPQVTRERIAER
LGLPFDNVTFNVTLLGGGFGRKSKPDFVVEAAVLAKEFPGKAVRVQWTREDDIHNSYFHTVSAEYLKAGVGKDGLPSAWL
HRTVAPSITALFAPGMNHEAAFELGMGFTNMAYAIPNVRLENPEATVHTRVGWYRSVSNIPHGFAIQSFVDELAHKAKED
PLKYQIKLLGPDRQIDPRTLSEEWNYGESPERYPIDTGRMRTVLETAAKAAGWGRQLPKGRGLGLAVHYSFVTYVAAVIE
VEVKDDGTLIVHKADIAVDCGPQINPERIRSQFEGACVMGLGNAVWGEISFKDGKVQQDNFHMYEVARMSLAPKEVAVHL
VTPPGEVPLGGVGEPGVPPIAPALCNAIFAATGQRIRNLPVRYQLQGWQKAQA

Sequences:

>Translated_773_residues
MSRLPNDFALSNLSRRGFLKGVGATGALVLAASWGWQGALAEDKPKQFGADGMPNGWIDDPKVYVSIAADGTVTVVCNRS
EMGQGVRTSLTMVIADELEADWAHVKVQQAPGDEVRFGNQDTDGSRSMRHWYEPMRRCGAAARIMLEQAAAAQWKVPVGE
CRAQLHKVIHTPSGRELGYGELAAAASALTVPARDSLRLKQPSEFRYIGKQGTKAIDGADIVNGRAVYGADVHFDGMLFA
VIARPAVYGGKVKSVDDSAALKVPGVLKVIQIEPRPLPSEFQPLGGVAVVASNTWAALKGREALKIEWDDGPNATYDSVA
YRKEIEAASLKPGKVVRNTGDIDKAIGSAASTLEASYYLPHLAQAPMEPMVAIARYKDDTCEAWAPSQAPQVTRERIAER
LGLPFDNVTFNVTLLGGGFGRKSKPDFVVEAAVLAKEFPGKAVRVQWTREDDIHNSYFHTVSAEYLKAGVGKDGLPSAWL
HRTVAPSITALFAPGMNHEAAFELGMGFTNMAYAIPNVRLENPEATVHTRVGWYRSVSNIPHGFAIQSFVDELAHKAKED
PLKYQIKLLGPDRQIDPRTLSEEWNYGESPERYPIDTGRMRTVLETAAKAAGWGRQLPKGRGLGLAVHYSFVTYVAAVIE
VEVKDDGTLIVHKADIAVDCGPQINPERIRSQFEGACVMGLGNAVWGEISFKDGKVQQDNFHMYEVARMSLAPKEVAVHL
VTPPGEVPLGGVGEPGVPPIAPALCNAIFAATGQRIRNLPVRYQLQGWQKAQA
>Mature_772_residues
SRLPNDFALSNLSRRGFLKGVGATGALVLAASWGWQGALAEDKPKQFGADGMPNGWIDDPKVYVSIAADGTVTVVCNRSE
MGQGVRTSLTMVIADELEADWAHVKVQQAPGDEVRFGNQDTDGSRSMRHWYEPMRRCGAAARIMLEQAAAAQWKVPVGEC
RAQLHKVIHTPSGRELGYGELAAAASALTVPARDSLRLKQPSEFRYIGKQGTKAIDGADIVNGRAVYGADVHFDGMLFAV
IARPAVYGGKVKSVDDSAALKVPGVLKVIQIEPRPLPSEFQPLGGVAVVASNTWAALKGREALKIEWDDGPNATYDSVAY
RKEIEAASLKPGKVVRNTGDIDKAIGSAASTLEASYYLPHLAQAPMEPMVAIARYKDDTCEAWAPSQAPQVTRERIAERL
GLPFDNVTFNVTLLGGGFGRKSKPDFVVEAAVLAKEFPGKAVRVQWTREDDIHNSYFHTVSAEYLKAGVGKDGLPSAWLH
RTVAPSITALFAPGMNHEAAFELGMGFTNMAYAIPNVRLENPEATVHTRVGWYRSVSNIPHGFAIQSFVDELAHKAKEDP
LKYQIKLLGPDRQIDPRTLSEEWNYGESPERYPIDTGRMRTVLETAAKAAGWGRQLPKGRGLGLAVHYSFVTYVAAVIEV
EVKDDGTLIVHKADIAVDCGPQINPERIRSQFEGACVMGLGNAVWGEISFKDGKVQQDNFHMYEVARMSLAPKEVAVHLV
TPPGEVPLGGVGEPGVPPIAPALCNAIFAATGQRIRNLPVRYQLQGWQKAQA

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789230, Length=409, Percent_Identity=24.4498777506112, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1786478, Length=394, Percent_Identity=25.6345177664975, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1789246, Length=536, Percent_Identity=23.3208955223881, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 83843; Mature: 83712

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLPNDFALSNLSRRGFLKGVGATGALVLAASWGWQGALAEDKPKQFGADGMPNGWIDD
CCCCCCHHHHHHHHHCCCEECCCCCCEEEEEECCCCCCCCCCCCCHHCCCCCCCCCCCCC
PKVYVSIAADGTVTVVCNRSEMGQGVRTSLTMVIADELEADWAHVKVQQAPGDEVRFGNQ
CEEEEEEECCCEEEEEECCHHHCCCHHHEEEEEEECCCCCCEEEEEEECCCCCCCCCCCC
DTDGSRSMRHWYEPMRRCGAAARIMLEQAAAAQWKVPVGECRAQLHKVIHTPSGRELGYG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCH
ELAAAASALTVPARDSLRLKQPSEFRYIGKQGTKAIDGADIVNGRAVYGADVHFDGMLFA
HHHHHHHHEECCCCCCCCCCCCCHHEEECCCCCCCCCCCCCCCCCEEEECCCCCCCHHHH
VIARPAVYGGKVKSVDDSAALKVPGVLKVIQIEPRPLPSEFQPLGGVAVVASNTWAALKG
HHHCCHHCCCEECCCCCCCEEECCCEEEEEEECCCCCCCCCCCCCCEEEEECCCEEEECC
REALKIEWDDGPNATYDSVAYRKEIEAASLKPGKVVRNTGDIDKAIGSAASTLEASYYLP
CEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHCCC
HLAQAPMEPMVAIARYKDDTCEAWAPSQAPQVTRERIAERLGLPFDNVTFNVTLLGGGFG
HHHHCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCC
RKSKPDFVVEAAVLAKEFPGKAVRVQWTREDDIHNSYFHTVSAEYLKAGVGKDGLPSAWL
CCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHH
HRTVAPSITALFAPGMNHEAAFELGMGFTNMAYAIPNVRLENPEATVHTRVGWYRSVSNI
HHHHCCCHHHEECCCCCCCHHHHHCCCHHHHHEECCCCEECCCCCEEEEEHHHHHHHHCC
PHGFAIQSFVDELAHKAKEDPLKYQIKLLGPDRQIDPRTLSEEWNYGESPERYPIDTGRM
CCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHCCCCCCCCCCCCCCCHHH
RTVLETAAKAAGWGRQLPKGRGLGLAVHYSFVTYVAAVIEVEVKDDGTLIVHKADIAVDC
HHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHEEEEECCCCEEEEEECCEEEEC
GPQINPERIRSQFEGACVMGLGNAVWGEISFKDGKVQQDNFHMYEVARMSLAPKEVAVHL
CCCCCHHHHHHHHCCEEEEECCCCEEEEEEECCCCEECCCCCHHHHHHHHCCCCCEEEEE
VTPPGEVPLGGVGEPGVPPIAPALCNAIFAATGQRIRNLPVRYQLQGWQKAQA
ECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHCCCEEEEECCCCCCCC
>Mature Secondary Structure 
SRLPNDFALSNLSRRGFLKGVGATGALVLAASWGWQGALAEDKPKQFGADGMPNGWIDD
CCCCCHHHHHHHHHCCCEECCCCCCEEEEEECCCCCCCCCCCCCHHCCCCCCCCCCCCC
PKVYVSIAADGTVTVVCNRSEMGQGVRTSLTMVIADELEADWAHVKVQQAPGDEVRFGNQ
CEEEEEEECCCEEEEEECCHHHCCCHHHEEEEEEECCCCCCEEEEEEECCCCCCCCCCCC
DTDGSRSMRHWYEPMRRCGAAARIMLEQAAAAQWKVPVGECRAQLHKVIHTPSGRELGYG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCH
ELAAAASALTVPARDSLRLKQPSEFRYIGKQGTKAIDGADIVNGRAVYGADVHFDGMLFA
HHHHHHHHEECCCCCCCCCCCCCHHEEECCCCCCCCCCCCCCCCCEEEECCCCCCCHHHH
VIARPAVYGGKVKSVDDSAALKVPGVLKVIQIEPRPLPSEFQPLGGVAVVASNTWAALKG
HHHCCHHCCCEECCCCCCCEEECCCEEEEEEECCCCCCCCCCCCCCEEEEECCCEEEECC
REALKIEWDDGPNATYDSVAYRKEIEAASLKPGKVVRNTGDIDKAIGSAASTLEASYYLP
CEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHCCC
HLAQAPMEPMVAIARYKDDTCEAWAPSQAPQVTRERIAERLGLPFDNVTFNVTLLGGGFG
HHHHCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCC
RKSKPDFVVEAAVLAKEFPGKAVRVQWTREDDIHNSYFHTVSAEYLKAGVGKDGLPSAWL
CCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHH
HRTVAPSITALFAPGMNHEAAFELGMGFTNMAYAIPNVRLENPEATVHTRVGWYRSVSNI
HHHHCCCHHHEECCCCCCCHHHHHCCCHHHHHEECCCCEECCCCCEEEEEHHHHHHHHCC
PHGFAIQSFVDELAHKAKEDPLKYQIKLLGPDRQIDPRTLSEEWNYGESPERYPIDTGRM
CCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHCCCCCCCCCCCCCCCHHH
RTVLETAAKAAGWGRQLPKGRGLGLAVHYSFVTYVAAVIEVEVKDDGTLIVHKADIAVDC
HHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHEEEEECCCCEEEEEECCEEEEC
GPQINPERIRSQFEGACVMGLGNAVWGEISFKDGKVQQDNFHMYEVARMSLAPKEVAVHL
CCCCCHHHHHHHHCCEEEEECCCCEEEEEEECCCCEECCCCCHHHHHHHHCCCCCEEEEE
VTPPGEVPLGGVGEPGVPPIAPALCNAIFAATGQRIRNLPVRYQLQGWQKAQA
ECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]