Click here to switch to the map view.

The map label for this gene is pabC [H]

Identifier: 77460375

GI number: 77460375

Start: 4691575

End: 4692390

Strand: Reverse

Name: pabC [H]

Synonym: Pfl01_4154

Alternate gene names: 77460375

Gene position: 4692390-4691575 (Counterclockwise)

Preceding gene: 255961264

Following gene: 77460374

Centisome position: 72.88

GC content: 62.01

Gene sequence:

>816_bases
ATGGACTGCTGGGTCGACGGTCTGCCGGCTGACGCTCTGTCGCTGAAAGATCGCGGCCTGGCTTACGGCGACGGTCTGTT
CGAGACCATCGCCGTGCGAGGTGGCCAGCCATTGCTGCTGGATCGGCATCTGACGCGTCTGGCCGACGGCTGTGCACGTC
TGGCCATTGCCGCCGACATCGAGCGGGTTCGCCATGAGCTGCAATCCTATGCCGCCGCGATGGGTGAGGGCGTGCTCAAA
CTCATCCTCACCCGTGGCGACGGATTGCGCGGTTATGCACCGGATCCTTCGGCGCAGGGCCGACGCATTCTGCAAGGCAA
TCCTCCCGCCGCTTACCCGGCTGCCTACGCCGAGCAGGGCGTTCGCCTTTTCCCGTGCAGCACGCGTTTGTCGATTCAGC
CGTTGCTTGCCGGGCTCAAACACCTCAATCGACTGGAGCAGGTCATTGCCCGCGCCGAATGGCAGGACAGTGAGCATGCC
GAAGGTTTGATGCTCGACCAGGCCGGTCGGGTAATCGAAGGTGTGTTCAGCAATCTGTTTCTGGTGCGTGACGGTGTGCT
GATCACGGCGGACCTGAAACGCTGCGGCGTAGCCGGTGTGATGCGCGCAGAAATATTGTTTCAGGCCAAGTCCCTGGGCA
TTCCCGTACAAATCACCGACATCCCCCTCGAACAGCTGCAATGGGCCGATGAAGTCTTTGTCTGCAATAGCGTGTATGGC
GTCTGGCCGGTACGCGCCTGTGCTGCTCTGAGCTGGCCGGTTGGCCCGCTCACCCGTAAACTGCAAACCATTGCCCGCGC
GCTACTGGATGCCTGA

Upstream 100 bases:

>100_bases
CGCACACCGCGCGCAATATGGATATCGATGTCGTGCTGTCCAACTCGTTCGGGTTTGGCGGCACCAACGGCACGCTGGCG
TTCCGTCGGTTCGCCGGCTG

Downstream 100 bases:

>100_bases
TTCGTGAGACGTAAACTTTTGCTGCTGCTGGAAACCGGACTGGTTCTGGCAGGGCTGCTGTTGGGCGCCAGCGCCTGGAA
GATTCATTCGGCACTGGAAC

Product: 4-amino-4-deoxychorismate lyase

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MDCWVDGLPADALSLKDRGLAYGDGLFETIAVRGGQPLLLDRHLTRLADGCARLAIAADIERVRHELQSYAAAMGEGVLK
LILTRGDGLRGYAPDPSAQGRRILQGNPPAAYPAAYAEQGVRLFPCSTRLSIQPLLAGLKHLNRLEQVIARAEWQDSEHA
EGLMLDQAGRVIEGVFSNLFLVRDGVLITADLKRCGVAGVMRAEILFQAKSLGIPVQITDIPLEQLQWADEVFVCNSVYG
VWPVRACAALSWPVGPLTRKLQTIARALLDA

Sequences:

>Translated_271_residues
MDCWVDGLPADALSLKDRGLAYGDGLFETIAVRGGQPLLLDRHLTRLADGCARLAIAADIERVRHELQSYAAAMGEGVLK
LILTRGDGLRGYAPDPSAQGRRILQGNPPAAYPAAYAEQGVRLFPCSTRLSIQPLLAGLKHLNRLEQVIARAEWQDSEHA
EGLMLDQAGRVIEGVFSNLFLVRDGVLITADLKRCGVAGVMRAEILFQAKSLGIPVQITDIPLEQLQWADEVFVCNSVYG
VWPVRACAALSWPVGPLTRKLQTIARALLDA
>Mature_271_residues
MDCWVDGLPADALSLKDRGLAYGDGLFETIAVRGGQPLLLDRHLTRLADGCARLAIAADIERVRHELQSYAAAMGEGVLK
LILTRGDGLRGYAPDPSAQGRRILQGNPPAAYPAAYAEQGVRLFPCSTRLSIQPLLAGLKHLNRLEQVIARAEWQDSEHA
EGLMLDQAGRVIEGVFSNLFLVRDGVLITADLKRCGVAGVMRAEILFQAKSLGIPVQITDIPLEQLQWADEVFVCNSVYG
VWPVRACAALSWPVGPLTRKLQTIARALLDA

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=264, Percent_Identity=37.5, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI48994963, Length=264, Percent_Identity=26.8939393939394, Blast_Score=74, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017824
- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 29428; Mature: 29428

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDCWVDGLPADALSLKDRGLAYGDGLFETIAVRGGQPLLLDRHLTRLADGCARLAIAADI
CCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ERVRHELQSYAAAMGEGVLKLILTRGDGLRGYAPDPSAQGRRILQGNPPAAYPAAYAEQG
HHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHCC
VRLFPCSTRLSIQPLLAGLKHLNRLEQVIARAEWQDSEHAEGLMLDQAGRVIEGVFSNLF
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHH
LVRDGVLITADLKRCGVAGVMRAEILFQAKSLGIPVQITDIPLEQLQWADEVFVCNSVYG
HHCCCEEEEECHHHCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHEEECCCCC
VWPVRACAALSWPVGPLTRKLQTIARALLDA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDCWVDGLPADALSLKDRGLAYGDGLFETIAVRGGQPLLLDRHLTRLADGCARLAIAADI
CCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ERVRHELQSYAAAMGEGVLKLILTRGDGLRGYAPDPSAQGRRILQGNPPAAYPAAYAEQG
HHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHCC
VRLFPCSTRLSIQPLLAGLKHLNRLEQVIARAEWQDSEHAEGLMLDQAGRVIEGVFSNLF
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHH
LVRDGVLITADLKRCGVAGVMRAEILFQAKSLGIPVQITDIPLEQLQWADEVFVCNSVYG
HHCCCEEEEECHHHCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHEEECCCCC
VWPVRACAALSWPVGPLTRKLQTIARALLDA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]