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The map label for this gene is serC [H]

Identifier: 77460298

GI number: 77460298

Start: 4606535

End: 4607626

Strand: Reverse

Name: serC [H]

Synonym: Pfl01_4077

Alternate gene names: 77460298

Gene position: 4607626-4606535 (Counterclockwise)

Preceding gene: 77460299

Following gene: 77460297

Centisome position: 71.56

GC content: 61.17

Gene sequence:

>1092_bases
GTGGATGTGAGCAAACGAGCCTTTAACTTCTGCGCAGGTCCCGCTGCGCTGCCTGAAGCTGTCCTGTTGCGTGCCCAGTC
CGAGATGCTCGACTGGCACGGCAAGGGTCTGTCGGTCATGGAAATGAGCCATCGCAGTGATGACTACGTGGCCATCGCCG
AGAAGGCCGAACAAGACCTGCGCGACCTGCTGTCCATCCCCTCCAATTACAAAGTGCTGTTCCTGCAGGGCGGTGCGAGC
CAACAGTTCGCCGAGATTCCGCTGAACCTGCTGCCTGAGAACGGCACTGCCGACTATGTCGAAACCGGCATCTGGTCGAA
GAAAGCCATCGAGGAAGCGCGTCGCTTCGGCAACATCAACGTTGCTGCCAGCGCCAAGCCTTATGACTACCTGGCCATCC
CTGGCCAGAACGAGTGGAAGCTGACCCCGGGTGCGGCCTATCTGCACTACGCATCCAACGAAACCATCGGCGGCCTGCAG
TTCGACTGGGTTCCCGAGGCCGGTGACGTTCCGCTGGTGGTCGACATGTCCTCCGATATCCTCTCGCGTCCGATCGATGT
GTCGCAGTACGGCCTGATCTACGCCGGCGCGCAAAAGAACATCGGCCCGAGCGGTCTGGTGGTAGTGATCGTCCGTGAAG
ACCTGCTGGGCCGCGCCCGCAGTTCGTGCCCGACCATGCTCGACTACAAGATCTCGGCCGATAACGGTTCGATGTACAAC
ACCCCGGCCACCTATTCCTGGTACCTCTCGGGTCTCGTCTTCGAATGGCTCAAGGAGCAGGGCGGCGTCGCCGCGATGGA
GCAGCGCAACAAGGCGAAGAAAGATCGCCTGTACGCCTTCATCGACAACAGCGACTTCTATACCAACCCGATCAGCGTCA
ACGCCCGTTCGTGGATGAACGTGCCGTTCCGCCTGGCTGACGAGCGTCTGGACAAGGCGTTCCTGGCCGGCGCCGACGCC
CGTGGCCTGCTCAACCTCAAGGGTCATCGTTCGGTCGGCGGCATGCGTGCCTCGATCTACAACGCCCTGGGTCTGGACGC
CGTCGAAGCGCTGGTCGGCTACATGGCTGAATTCGAGAAGGAGCATTCCTGA

Upstream 100 bases:

>100_bases
CTGCAGGCGGACGCCGCAGACGAAGAAGAGTCGCAAGACTAACCAAATCGTAGCAGGGCAGAGTGTTTGCTCTGTCCGCT
ACCGTGATTGCATAGCGAGA

Downstream 100 bases:

>100_bases
TGTCCGAGCAGGAGCTCAAGGCGCTGCGCGTTCGCATCGATAACCTGGATGAGAAGATCCTCCAGCTGATCAGCGATCGC
GCGCGCTGCGCCGAAGAAGT

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MDVSKRAFNFCAGPAALPEAVLLRAQSEMLDWHGKGLSVMEMSHRSDDYVAIAEKAEQDLRDLLSIPSNYKVLFLQGGAS
QQFAEIPLNLLPENGTADYVETGIWSKKAIEEARRFGNINVAASAKPYDYLAIPGQNEWKLTPGAAYLHYASNETIGGLQ
FDWVPEAGDVPLVVDMSSDILSRPIDVSQYGLIYAGAQKNIGPSGLVVVIVREDLLGRARSSCPTMLDYKISADNGSMYN
TPATYSWYLSGLVFEWLKEQGGVAAMEQRNKAKKDRLYAFIDNSDFYTNPISVNARSWMNVPFRLADERLDKAFLAGADA
RGLLNLKGHRSVGGMRASIYNALGLDAVEALVGYMAEFEKEHS

Sequences:

>Translated_363_residues
MDVSKRAFNFCAGPAALPEAVLLRAQSEMLDWHGKGLSVMEMSHRSDDYVAIAEKAEQDLRDLLSIPSNYKVLFLQGGAS
QQFAEIPLNLLPENGTADYVETGIWSKKAIEEARRFGNINVAASAKPYDYLAIPGQNEWKLTPGAAYLHYASNETIGGLQ
FDWVPEAGDVPLVVDMSSDILSRPIDVSQYGLIYAGAQKNIGPSGLVVVIVREDLLGRARSSCPTMLDYKISADNGSMYN
TPATYSWYLSGLVFEWLKEQGGVAAMEQRNKAKKDRLYAFIDNSDFYTNPISVNARSWMNVPFRLADERLDKAFLAGADA
RGLLNLKGHRSVGGMRASIYNALGLDAVEALVGYMAEFEKEHS
>Mature_363_residues
MDVSKRAFNFCAGPAALPEAVLLRAQSEMLDWHGKGLSVMEMSHRSDDYVAIAEKAEQDLRDLLSIPSNYKVLFLQGGAS
QQFAEIPLNLLPENGTADYVETGIWSKKAIEEARRFGNINVAASAKPYDYLAIPGQNEWKLTPGAAYLHYASNETIGGLQ
FDWVPEAGDVPLVVDMSSDILSRPIDVSQYGLIYAGAQKNIGPSGLVVVIVREDLLGRARSSCPTMLDYKISADNGSMYN
TPATYSWYLSGLVFEWLKEQGGVAAMEQRNKAKKDRLYAFIDNSDFYTNPISVNARSWMNVPFRLADERLDKAFLAGADA
RGLLNLKGHRSVGGMRASIYNALGLDAVEALVGYMAEFEKEHS

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=369, Percent_Identity=49.8644986449864, Blast_Score=381, Evalue=1e-106,
Organism=Homo sapiens, GI10863955, Length=365, Percent_Identity=44.9315068493151, Blast_Score=326, Evalue=2e-89,
Organism=Escherichia coli, GI1787136, Length=357, Percent_Identity=57.9831932773109, Blast_Score=424, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI17506897, Length=370, Percent_Identity=43.5135135135135, Blast_Score=326, Evalue=9e-90,
Organism=Saccharomyces cerevisiae, GI6324758, Length=386, Percent_Identity=39.119170984456, Blast_Score=255, Evalue=1e-68,
Organism=Drosophila melanogaster, GI21356589, Length=361, Percent_Identity=50.6925207756233, Blast_Score=372, Evalue=1e-103,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 39970; Mature: 39970

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVSKRAFNFCAGPAALPEAVLLRAQSEMLDWHGKGLSVMEMSHRSDDYVAIAEKAEQDL
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEHHHHHHHH
RDLLSIPSNYKVLFLQGGASQQFAEIPLNLLPENGTADYVETGIWSKKAIEEARRFGNIN
HHHHHCCCCCEEEEEECCCCCCHHHCCCEEECCCCCHHHHHHCCCCHHHHHHHHHCCCEE
VAASAKPYDYLAIPGQNEWKLTPGAAYLHYASNETIGGLQFDWVPEAGDVPLVVDMSSDI
EEECCCCCEEEEECCCCCEEECCCCEEEEECCCCCCCCEEEEECCCCCCCCEEEECCHHH
LSRPIDVSQYGLIYAGAQKNIGPSGLVVVIVREDLLGRARSSCPTMLDYKISADNGSMYN
HHCCCCCCCCCEEEECCCCCCCCCCEEEEEEECHHHHHHHHCCCCEEEEEEECCCCCEEC
TPATYSWYLSGLVFEWLKEQGGVAAMEQRNKAKKDRLYAFIDNSDFYTNPISVNARSWMN
CCCHHHHHHHHHHHHHHHHCCCEEHHHHHHHHCCCCEEEEECCCCCCCCCEEECCHHHCC
VPFRLADERLDKAFLAGADARGLLNLKGHRSVGGMRASIYNALGLDAVEALVGYMAEFEK
CCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHH
EHS
CCC
>Mature Secondary Structure
MDVSKRAFNFCAGPAALPEAVLLRAQSEMLDWHGKGLSVMEMSHRSDDYVAIAEKAEQDL
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEHHHHHHHH
RDLLSIPSNYKVLFLQGGASQQFAEIPLNLLPENGTADYVETGIWSKKAIEEARRFGNIN
HHHHHCCCCCEEEEEECCCCCCHHHCCCEEECCCCCHHHHHHCCCCHHHHHHHHHCCCEE
VAASAKPYDYLAIPGQNEWKLTPGAAYLHYASNETIGGLQFDWVPEAGDVPLVVDMSSDI
EEECCCCCEEEEECCCCCEEECCCCEEEEECCCCCCCCEEEEECCCCCCCCEEEECCHHH
LSRPIDVSQYGLIYAGAQKNIGPSGLVVVIVREDLLGRARSSCPTMLDYKISADNGSMYN
HHCCCCCCCCCEEEECCCCCCCCCCEEEEEEECHHHHHHHHCCCCEEEEEEECCCCCEEC
TPATYSWYLSGLVFEWLKEQGGVAAMEQRNKAKKDRLYAFIDNSDFYTNPISVNARSWMN
CCCHHHHHHHHHHHHHHHHCCCEEHHHHHHHHCCCCEEEEECCCCCCCCCEEECCHHHCC
VPFRLADERLDKAFLAGADARGLLNLKGHRSVGGMRASIYNALGLDAVEALVGYMAEFEK
CCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHH
EHS
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA