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The map label for this gene is udg [H]

Identifier: 77460291

GI number: 77460291

Start: 4597099

End: 4598448

Strand: Direct

Name: udg [H]

Synonym: Pfl01_4070

Alternate gene names: 77460291

Gene position: 4597099-4598448 (Clockwise)

Preceding gene: 77460290

Following gene: 77460292

Centisome position: 71.4

GC content: 57.48

Gene sequence:

>1350_bases
ATGCGAGTTACAGTTTTCGGCACCGGGTATGTCGGACTCGTCACGGGCGCTTGCCTTGCAGATGTTGGACATGACGTGAT
GTGTGTCGATGTCGATAACGCGAAAATCGAGAGCTTGAAGCAAGGCATCATCCCGATCTACGAACCGGGACTGGACGCAC
TGGTGGCACAGAACCAACGCGAGGGCCGCCTGCACTTCACAACCGACGCCAGGCAAGCCGTGGACTTTGGCCAATTGCAA
ATGATCGCGGTGGGCACCCCGCCCAACGAGGATGGTTCTGCCGACCTGCAGCATGTGCTGGCCGTCGCTCGCACCATCGG
CGAGTACATGACCGAGCACAAAGTGATCGTGAACAAGTCGACGGTTCCGGTAGGCACTGCCGACAAAGTCAGCCGGACCG
TCGACGCGATCCTGCAGGCCAGAGACGCCGGGCTCGACTTCGATGTCTGTTCCAATCCCGAGTTTCTCAAGGAAGGCTCG
GCCATCGAGGACTTTGCCAAAGGTGCCCGTATTATCGTCGGGACCGAATCCGAAACGGTCAAAGCAATCATGCGCGAGTG
CTACGCACCTTATAGCCGCAACCACGACAAATTGATTTTCATGGATGTGCGCGCCGCCGAACTGACGAAGTATGCGGCCA
ATGCGATGCTGGCGACCAAGATCAGCTTCATGAACGAAATCGCACAGATGGCAGAGCGGCTGGGGGCCGATATCGAACAG
GTCCGGCTGGGTATCGGCTCCGATCCACGTATCGGTTTCCAGTTCATTTACCCCGGTTGTGGATACGGCGGCTCATGCTT
CCCGAAAGACGTTCAGGCGCTCGCCCGCACGGCTCAGGAAATCGGCTATGAGGCGCAACTGTTGAACGCCGTCGAGGCCG
TCAACAACCGCCAGAAGAACGTGATGTTCGAGAAGCTGTCCCTCGCCTTCGATCACGACCTGAAGAACAAGACCATCGCT
GTCTGGGGCTTGTCTTTCAAACCCAACACTGACGACATGCGCGCAGCGCCCAGTCGCAATCTGATCGAAGCAATCTGGGC
GGCAGGTGGAAAAGTCCAGGCATTCGACCCGGCCGCCATGAGCGAGGCCACGCGCATTTACGGAGCACGCGACGATCTGC
AACTGACAGCCAATCGTGAAATGGCACTGGAAGGCGCCGATGCCCTGGTAATTTGCACAGAATGGAAACAATTTCGCACT
GTCGACTTCAAGAAGCTGAAAACCTGCCTTAATTACCCGGTACTGGTCGACGGGCGTAACCTGTTTGACCCTGCCGCGGC
CAAGGAGGCAGGGTTCATGTACTACGCAATCGGTCGTGCTGACTCGCTCATGCCCGTTCTGCAACCTTAA

Upstream 100 bases:

>100_bases
GTACACAAACTGATCAATCGGATCAAATTCGCCTTCTCACGCAGTGATTCTCTTTAATCAGCCCCTTGATAGCGGCCCCG
AATTTATCAGGATGTAAATT

Downstream 100 bases:

>100_bases
GGAGCTGTCCCATGAAGATACTCGTGACTGGCGCAGCCGGTTTCATCGGCTTTCATGTCAGCCAGGCGCTGCTTGCCCGC
GGCGATGAAGTCGTTGGCAT

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MRVTVFGTGYVGLVTGACLADVGHDVMCVDVDNAKIESLKQGIIPIYEPGLDALVAQNQREGRLHFTTDARQAVDFGQLQ
MIAVGTPPNEDGSADLQHVLAVARTIGEYMTEHKVIVNKSTVPVGTADKVSRTVDAILQARDAGLDFDVCSNPEFLKEGS
AIEDFAKGARIIVGTESETVKAIMRECYAPYSRNHDKLIFMDVRAAELTKYAANAMLATKISFMNEIAQMAERLGADIEQ
VRLGIGSDPRIGFQFIYPGCGYGGSCFPKDVQALARTAQEIGYEAQLLNAVEAVNNRQKNVMFEKLSLAFDHDLKNKTIA
VWGLSFKPNTDDMRAAPSRNLIEAIWAAGGKVQAFDPAAMSEATRIYGARDDLQLTANREMALEGADALVICTEWKQFRT
VDFKKLKTCLNYPVLVDGRNLFDPAAAKEAGFMYYAIGRADSLMPVLQP

Sequences:

>Translated_449_residues
MRVTVFGTGYVGLVTGACLADVGHDVMCVDVDNAKIESLKQGIIPIYEPGLDALVAQNQREGRLHFTTDARQAVDFGQLQ
MIAVGTPPNEDGSADLQHVLAVARTIGEYMTEHKVIVNKSTVPVGTADKVSRTVDAILQARDAGLDFDVCSNPEFLKEGS
AIEDFAKGARIIVGTESETVKAIMRECYAPYSRNHDKLIFMDVRAAELTKYAANAMLATKISFMNEIAQMAERLGADIEQ
VRLGIGSDPRIGFQFIYPGCGYGGSCFPKDVQALARTAQEIGYEAQLLNAVEAVNNRQKNVMFEKLSLAFDHDLKNKTIA
VWGLSFKPNTDDMRAAPSRNLIEAIWAAGGKVQAFDPAAMSEATRIYGARDDLQLTANREMALEGADALVICTEWKQFRT
VDFKKLKTCLNYPVLVDGRNLFDPAAAKEAGFMYYAIGRADSLMPVLQP
>Mature_449_residues
MRVTVFGTGYVGLVTGACLADVGHDVMCVDVDNAKIESLKQGIIPIYEPGLDALVAQNQREGRLHFTTDARQAVDFGQLQ
MIAVGTPPNEDGSADLQHVLAVARTIGEYMTEHKVIVNKSTVPVGTADKVSRTVDAILQARDAGLDFDVCSNPEFLKEGS
AIEDFAKGARIIVGTESETVKAIMRECYAPYSRNHDKLIFMDVRAAELTKYAANAMLATKISFMNEIAQMAERLGADIEQ
VRLGIGSDPRIGFQFIYPGCGYGGSCFPKDVQALARTAQEIGYEAQLLNAVEAVNNRQKNVMFEKLSLAFDHDLKNKTIA
VWGLSFKPNTDDMRAAPSRNLIEAIWAAGGKVQAFDPAAMSEATRIYGARDDLQLTANREMALEGADALVICTEWKQFRT
VDFKKLKTCLNYPVLVDGRNLFDPAAAKEAGFMYYAIGRADSLMPVLQP

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=464, Percent_Identity=31.8965517241379, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI296040438, Length=366, Percent_Identity=31.9672131147541, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI296040443, Length=319, Percent_Identity=31.6614420062696, Blast_Score=148, Evalue=8e-36,
Organism=Escherichia coli, GI1788340, Length=362, Percent_Identity=27.9005524861878, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI48994968, Length=417, Percent_Identity=26.378896882494, Blast_Score=127, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17560350, Length=470, Percent_Identity=33.1914893617021, Blast_Score=234, Evalue=5e-62,
Organism=Drosophila melanogaster, GI17136908, Length=467, Percent_Identity=31.6916488222698, Blast_Score=224, Evalue=8e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 49069; Mature: 49069

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVTVFGTGYVGLVTGACLADVGHDVMCVDVDNAKIESLKQGIIPIYEPGLDALVAQNQR
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCEEECCCHHHHHHCCCC
EGRLHFTTDARQAVDFGQLQMIAVGTPPNEDGSADLQHVLAVARTIGEYMTEHKVIVNKS
CCCEEEECCHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECC
TVPVGTADKVSRTVDAILQARDAGLDFDVCSNPEFLKEGSAIEDFAKGARIIVGTESETV
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHCCCEEEEECCHHHH
KAIMRECYAPYSRNHDKLIFMDVRAAELTKYAANAMLATKISFMNEIAQMAERLGADIEQ
HHHHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRLGIGSDPRIGFQFIYPGCGYGGSCFPKDVQALARTAQEIGYEAQLLNAVEAVNNRQKN
HHCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHH
VMFEKLSLAFDHDLKNKTIAVWGLSFKPNTDDMRAAPSRNLIEAIWAAGGKVQAFDPAAM
HHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHHHCCCCCHHHHHHHHCCCEEEECCCHHH
SEATRIYGARDDLQLTANREMALEGADALVICTEWKQFRTVDFKKLKTCLNYPVLVDGRN
HHHHHHHCCCCCEEEECCCEEEECCCCEEEEEECCHHHHCCCHHHHHHHHCCCEEECCCC
LFDPAAAKEAGFMYYAIGRADSLMPVLQP
CCCCCHHHHCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MRVTVFGTGYVGLVTGACLADVGHDVMCVDVDNAKIESLKQGIIPIYEPGLDALVAQNQR
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCEEECCCHHHHHHCCCC
EGRLHFTTDARQAVDFGQLQMIAVGTPPNEDGSADLQHVLAVARTIGEYMTEHKVIVNKS
CCCEEEECCHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECC
TVPVGTADKVSRTVDAILQARDAGLDFDVCSNPEFLKEGSAIEDFAKGARIIVGTESETV
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHCCCEEEEECCHHHH
KAIMRECYAPYSRNHDKLIFMDVRAAELTKYAANAMLATKISFMNEIAQMAERLGADIEQ
HHHHHHHCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRLGIGSDPRIGFQFIYPGCGYGGSCFPKDVQALARTAQEIGYEAQLLNAVEAVNNRQKN
HHCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHH
VMFEKLSLAFDHDLKNKTIAVWGLSFKPNTDDMRAAPSRNLIEAIWAAGGKVQAFDPAAM
HHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHHHCCCCCHHHHHHHHCCCEEEECCCHHH
SEATRIYGARDDLQLTANREMALEGADALVICTEWKQFRTVDFKKLKTCLNYPVLVDGRN
HHHHHHHCCCCCEEEECCCEEEECCCCEEEEEECCHHHHCCCHHHHHHHHCCCEEECCCC
LFDPAAAKEAGFMYYAIGRADSLMPVLQP
CCCCCHHHHCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]