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The map label for this gene is aroF [H]

Identifier: 77460230

GI number: 77460230

Start: 4534887

End: 4535963

Strand: Direct

Name: aroF [H]

Synonym: Pfl01_4009

Alternate gene names: 77460230

Gene position: 4534887-4535963 (Clockwise)

Preceding gene: 77460229

Following gene: 77460232

Centisome position: 70.43

GC content: 60.82

Gene sequence:

>1077_bases
ATGGCTGATTTACCGATCAACGACCTGAACGTCGCTTCCAACGAGACCCTGATCACTCCCGATCAGCTCAAGCGTGATAT
CCCTCTGAGCGACGCTGCCCTGCGCACCGTCACAAAGGGTCGCGAGGTCATCCGCAACATTCTCGATGGCACCGACCATC
GTCTGTTCGTGGTGATCGGCCCCTGCTCGATCCACGACATCAAGGCTGCCCACGAATATGCCGATCGCCTGAAGGTGCTG
GCGGCAGAAGTCTCGGACACCCTGTATCTGGTCATGCGCGTGTATTTCGAGAAACCACGGACCACCGTCGGCTGGAAAGG
CCTTATCAACGACCCGTACCTGGATGACTCGTTCAAAATCCAGGACGGTCTGCACATCGGTCGCCAGTTGCTGCTGGACC
TGGCCGAGAAAGGCCTGCCGACCGCAACCGAAGCCCTCGACCCGATCTCCCCGCAGTATCTGCAGGACCTGATCAGCTGG
TCGGCCATCGGCGCCCGTACCACCGAATCCCAGACCCACCGCGAGATGGCTTCCGGCCTGTCTTCGGCGGTCGGCTTCAA
GAACGGCACCGACGGCGGCCTGACTGTGGCGATCAACGCCTTGCAGTCGGTTTCCAGCCCGCACCGTTTCCTGGGTATCA
ACCAGGAAGGTGGCGTGTCGATCGTCACCACCAAAGGCAACGCCTACGGTCATGTGGTGCTGCGCGGCGGCAACGGCAAG
CCGAACTACGACTCGGTCAGCGTCGCCCTGTGCGAGCAGGCGCTGAACAAGGCGAAGATCAAGCCGAACATCATGGTCGA
CTGCAGCCACGCCAACTCCAACAAGGATCCGGCCCTGCAACCGTTGGTGATGGAGAACGTCGCCAACCAGATCCTCGAAG
GCAACCAGTCGATCATCGGCCTGATGGTCGAAAGTCACCTGAACTGGGGCTGCCAGGCGATCCCGAAAGACCTCGCCGAC
CTGCAATACGGCGTGTCGATCACCGATGCGTGCATCGACTGGTCCGCTACCGAAAACACCTTGCGCAGCATGCACGCCAA
GCTCAAGGATGTCCTGCCGAAACGTCAGCGCGGCTGA

Upstream 100 bases:

>100_bases
CTAACGCGATAAGGTTCGGCTCCCCGACGCGCTTAAATCCGCTGTGCTCCGCCGCGCGGGGATCGCTGGCGGCCGGCACC
CGTGACCTGACGAGTAAACG

Downstream 100 bases:

>100_bases
CAGGCGTTTCGCAGGCATAAAAAAACGCCGGGCATTGCCCGGCGTTTTTGTGTGTGCGGTGAGGTCAGTCAGATCTTGGC
GGTGCGCCGCTGATGACGCT

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MADLPINDLNVASNETLITPDQLKRDIPLSDAALRTVTKGREVIRNILDGTDHRLFVVIGPCSIHDIKAAHEYADRLKVL
AAEVSDTLYLVMRVYFEKPRTTVGWKGLINDPYLDDSFKIQDGLHIGRQLLLDLAEKGLPTATEALDPISPQYLQDLISW
SAIGARTTESQTHREMASGLSSAVGFKNGTDGGLTVAINALQSVSSPHRFLGINQEGGVSIVTTKGNAYGHVVLRGGNGK
PNYDSVSVALCEQALNKAKIKPNIMVDCSHANSNKDPALQPLVMENVANQILEGNQSIIGLMVESHLNWGCQAIPKDLAD
LQYGVSITDACIDWSATENTLRSMHAKLKDVLPKRQRG

Sequences:

>Translated_358_residues
MADLPINDLNVASNETLITPDQLKRDIPLSDAALRTVTKGREVIRNILDGTDHRLFVVIGPCSIHDIKAAHEYADRLKVL
AAEVSDTLYLVMRVYFEKPRTTVGWKGLINDPYLDDSFKIQDGLHIGRQLLLDLAEKGLPTATEALDPISPQYLQDLISW
SAIGARTTESQTHREMASGLSSAVGFKNGTDGGLTVAINALQSVSSPHRFLGINQEGGVSIVTTKGNAYGHVVLRGGNGK
PNYDSVSVALCEQALNKAKIKPNIMVDCSHANSNKDPALQPLVMENVANQILEGNQSIIGLMVESHLNWGCQAIPKDLAD
LQYGVSITDACIDWSATENTLRSMHAKLKDVLPKRQRG
>Mature_357_residues
ADLPINDLNVASNETLITPDQLKRDIPLSDAALRTVTKGREVIRNILDGTDHRLFVVIGPCSIHDIKAAHEYADRLKVLA
AEVSDTLYLVMRVYFEKPRTTVGWKGLINDPYLDDSFKIQDGLHIGRQLLLDLAEKGLPTATEALDPISPQYLQDLISWS
AIGARTTESQTHREMASGLSSAVGFKNGTDGGLTVAINALQSVSSPHRFLGINQEGGVSIVTTKGNAYGHVVLRGGNGKP
NYDSVSVALCEQALNKAKIKPNIMVDCSHANSNKDPALQPLVMENVANQILEGNQSIIGLMVESHLNWGCQAIPKDLADL
QYGVSITDACIDWSATENTLRSMHAKLKDVLPKRQRG

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=350, Percent_Identity=58.5714285714286, Blast_Score=427, Evalue=1e-121,
Organism=Escherichia coli, GI1786969, Length=343, Percent_Identity=53.6443148688047, Blast_Score=355, Evalue=3e-99,
Organism=Escherichia coli, GI1787996, Length=338, Percent_Identity=47.0414201183432, Blast_Score=314, Evalue=5e-87,
Organism=Saccharomyces cerevisiae, GI6319726, Length=343, Percent_Identity=50.4373177842566, Blast_Score=342, Evalue=4e-95,
Organism=Saccharomyces cerevisiae, GI6320240, Length=342, Percent_Identity=49.1228070175439, Blast_Score=337, Evalue=2e-93,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38937; Mature: 38806

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLPINDLNVASNETLITPDQLKRDIPLSDAALRTVTKGREVIRNILDGTDHRLFVVIG
CCCCCCCCCCCCCCCCEECHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
PCSIHDIKAAHEYADRLKVLAAEVSDTLYLVMRVYFEKPRTTVGWKGLINDPYLDDSFKI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEE
QDGLHIGRQLLLDLAEKGLPTATEALDPISPQYLQDLISWSAIGARTTESQTHREMASGL
HHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
SSAVGFKNGTDGGLTVAINALQSVSSPHRFLGINQEGGVSIVTTKGNAYGHVVLRGGNGK
HHHCCCCCCCCCCHHEEHHHHHHCCCCCCEEECCCCCCEEEEEECCCCEEEEEEECCCCC
PNYDSVSVALCEQALNKAKIKPNIMVDCSHANSNKDPALQPLVMENVANQILEGNQSIIG
CCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCHHEE
LMVESHLNWGCQAIPKDLADLQYGVSITDACIDWSATENTLRSMHAKLKDVLPKRQRG
HHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ADLPINDLNVASNETLITPDQLKRDIPLSDAALRTVTKGREVIRNILDGTDHRLFVVIG
CCCCCCCCCCCCCCCEECHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
PCSIHDIKAAHEYADRLKVLAAEVSDTLYLVMRVYFEKPRTTVGWKGLINDPYLDDSFKI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEE
QDGLHIGRQLLLDLAEKGLPTATEALDPISPQYLQDLISWSAIGARTTESQTHREMASGL
HHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
SSAVGFKNGTDGGLTVAINALQSVSSPHRFLGINQEGGVSIVTTKGNAYGHVVLRGGNGK
HHHCCCCCCCCCCHHEEHHHHHHCCCCCCEEECCCCCCEEEEEECCCCEEEEEEECCCCC
PNYDSVSVALCEQALNKAKIKPNIMVDCSHANSNKDPALQPLVMENVANQILEGNQSIIG
CCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCHHEE
LMVESHLNWGCQAIPKDLADLQYGVSITDACIDWSATENTLRSMHAKLKDVLPKRQRG
HHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]