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The map label for this gene is 77460227

Identifier: 77460227

GI number: 77460227

Start: 4532975

End: 4533928

Strand: Reverse

Name: 77460227

Synonym: Pfl01_4006

Alternate gene names: NA

Gene position: 4533928-4532975 (Counterclockwise)

Preceding gene: 77460228

Following gene: 77460226

Centisome position: 70.42

GC content: 62.05

Gene sequence:

>954_bases
ATGGGAGCAGTGAAAAAACCGGTGGTGGGGATTATCGGCACCGGCGCCATCGGAGGGTTCTACGGGGTGATGCTGGCCCG
GGCCGGGTTCGATGTGCACTTTTTGTTGCGCAGTGAATTTTCCGCAGTCGCCGAGCGCGGCTTGCAAGTGGACAGTGCTG
TGCATGGCGCATTGGCGCTGAACCCGGTGCAGGCTTATTCGTCGGCTGAAGACATGCCGCCCTGCGACTGGCTGCTGGTT
GGCGCCAAGACCACCAGCAATGCCGGGTTGGCGCCGTCGATCATTCAGGCGGCGAAGCCCGACGCGAAAGTGCTGGTGCT
GCAAAACGGCCTCGACGTCGAAGACAGTTTGCGTGCGTTGCTGCCCGATTCCCTGCATTTGCTGGGCGGCTTGTGCCTGA
TTTGCGTTCATCGCGAGGGGCCGGGCCAGATCACCCACCAGGCGCTGGGCGCAGTGAACGTCGGCTATCACAGCGGCCCG
GCAGCGGATGACGCGGCGCGCATGGCAATCGTCGAAGAGGGCGCCAGCCTGTTCCGCGCCGCCGGTCTTGATTCCCAGGC
GATGCCGAACCTGCATCAGGCGCGCTGGCAGAAACTGGTGTGGAACATTCCCTACAACGGCCTTTCGGTGTTGCTAGGCG
CCGGCACCACGCCGTTGATGGCCGACACGGACAGCCGCGCATTGATTCAGGCGCTGATGGCTGAAGTGGTGCAGGGCGCC
AAGGCCTGCGGCCACGACATGCCACCCGGTTACGCCGAATACCTGTTCATGATGACCGAGAAAATGCCCGATTATTGGCC
GAGCATGTACCACGACTTTTTACACAAGCGACCGCTGGAGCTGGAGGCGATCTACGCTCGTCCTTTGGCGGCGGCGAAAG
CGGCAGGCTGCGAGTTGCCGCGAATCGAATCGTTGTATCGCACATTGAGCTTTATCGACCGGCGCAACGTTTAA

Upstream 100 bases:

>100_bases
ACGGCGAGTTCTTTGGGGCTGTGCACACGCGTCTGAATGTCGATGAGCTGAATGCAGCCGTGACGCAGGCGCTAGGTCGA
ATTGCAGAGGAGTTGCCGTG

Downstream 100 bases:

>100_bases
ACCGGTCGCACTGGGGGAAAGGCATGGCCAAGAACATCGATGACAAACTGGTGCTGGCGATCTCGTCCCGTGCCCTGTTC
GACCTGAGCGAAAGCCACAA

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MGAVKKPVVGIIGTGAIGGFYGVMLARAGFDVHFLLRSEFSAVAERGLQVDSAVHGALALNPVQAYSSAEDMPPCDWLLV
GAKTTSNAGLAPSIIQAAKPDAKVLVLQNGLDVEDSLRALLPDSLHLLGGLCLICVHREGPGQITHQALGAVNVGYHSGP
AADDAARMAIVEEGASLFRAAGLDSQAMPNLHQARWQKLVWNIPYNGLSVLLGAGTTPLMADTDSRALIQALMAEVVQGA
KACGHDMPPGYAEYLFMMTEKMPDYWPSMYHDFLHKRPLELEAIYARPLAAAKAAGCELPRIESLYRTLSFIDRRNV

Sequences:

>Translated_317_residues
MGAVKKPVVGIIGTGAIGGFYGVMLARAGFDVHFLLRSEFSAVAERGLQVDSAVHGALALNPVQAYSSAEDMPPCDWLLV
GAKTTSNAGLAPSIIQAAKPDAKVLVLQNGLDVEDSLRALLPDSLHLLGGLCLICVHREGPGQITHQALGAVNVGYHSGP
AADDAARMAIVEEGASLFRAAGLDSQAMPNLHQARWQKLVWNIPYNGLSVLLGAGTTPLMADTDSRALIQALMAEVVQGA
KACGHDMPPGYAEYLFMMTEKMPDYWPSMYHDFLHKRPLELEAIYARPLAAAKAAGCELPRIESLYRTLSFIDRRNV
>Mature_316_residues
GAVKKPVVGIIGTGAIGGFYGVMLARAGFDVHFLLRSEFSAVAERGLQVDSAVHGALALNPVQAYSSAEDMPPCDWLLVG
AKTTSNAGLAPSIIQAAKPDAKVLVLQNGLDVEDSLRALLPDSLHLLGGLCLICVHREGPGQITHQALGAVNVGYHSGPA
ADDAARMAIVEEGASLFRAAGLDSQAMPNLHQARWQKLVWNIPYNGLSVLLGAGTTPLMADTDSRALIQALMAEVVQGAK
ACGHDMPPGYAEYLFMMTEKMPDYWPSMYHDFLHKRPLELEAIYARPLAAAKAAGCELPRIESLYRTLSFIDRRNV

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320057, Length=332, Percent_Identity=21.9879518072289, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 33899; Mature: 33767

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAVKKPVVGIIGTGAIGGFYGVMLARAGFDVHFLLRSEFSAVAERGLQVDSAVHGALAL
CCCCCCCCEEEEECCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCCHHHHHHHHHEE
NPVQAYSSAEDMPPCDWLLVGAKTTSNAGLAPSIIQAAKPDAKVLVLQNGLDVEDSLRAL
CHHHHHCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHCCCCCEEEEEECCCCHHHHHHHH
LPDSLHLLGGLCLICVHREGPGQITHQALGAVNVGYHSGPAADDAARMAIVEEGASLFRA
CCHHHHHHHCEEEEEEECCCCCHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHH
AGLDSQAMPNLHQARWQKLVWNIPYNGLSVLLGAGTTPLMADTDSRALIQALMAEVVQGA
CCCCCHHCCCHHHHHHHHHHHCCCCCCHHEEECCCCCCCEECCCHHHHHHHHHHHHHHHH
KACGHDMPPGYAEYLFMMTEKMPDYWPSMYHDFLHKRPLELEAIYARPLAAAKAAGCELP
HHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHCHHHHHHHCCCCCH
RIESLYRTLSFIDRRNV
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GAVKKPVVGIIGTGAIGGFYGVMLARAGFDVHFLLRSEFSAVAERGLQVDSAVHGALAL
CCCCCCCEEEEECCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCCHHHHHHHHHEE
NPVQAYSSAEDMPPCDWLLVGAKTTSNAGLAPSIIQAAKPDAKVLVLQNGLDVEDSLRAL
CHHHHHCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHCCCCCEEEEEECCCCHHHHHHHH
LPDSLHLLGGLCLICVHREGPGQITHQALGAVNVGYHSGPAADDAARMAIVEEGASLFRA
CCHHHHHHHCEEEEEEECCCCCHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHH
AGLDSQAMPNLHQARWQKLVWNIPYNGLSVLLGAGTTPLMADTDSRALIQALMAEVVQGA
CCCCCHHCCCHHHHHHHHHHHCCCCCCHHEEECCCCCCCEECCCHHHHHHHHHHHHHHHH
KACGHDMPPGYAEYLFMMTEKMPDYWPSMYHDFLHKRPLELEAIYARPLAAAKAAGCELP
HHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHCHHHHHHHCCCCCH
RIESLYRTLSFIDRRNV
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]