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The map label for this gene is zurA [H]

Identifier: 77460149

GI number: 77460149

Start: 4442805

End: 4443548

Strand: Direct

Name: zurA [H]

Synonym: Pfl01_3928

Alternate gene names: 77460149

Gene position: 4442805-4443548 (Clockwise)

Preceding gene: 77460148

Following gene: 77460150

Centisome position: 69.0

GC content: 66.67

Gene sequence:

>744_bases
ATGACAGCTCAGGAAAACCTGTCGATAGCCAGCAGCGGCCCGACCCTGGATTTCGCTGACATCAGCCTGACCCTCGGCCG
CACGACGATTCTGGACAAGGTCACCTTCCAGGTGCAGCCCGGCAGCGTGCATGCGCTGGTCGGTCCCAACGGCGGCGGCA
AGAGTTCGCTGATCAAGACCCTGCTCGGGCAGATGCCCCATCAGGGCCGGCTCAGCCTGCAATGGCCCGGCGAGCCCGGC
ACCATCGGTTACGTGCCGCAGGCGCTGGAGTTCGATCGGGGCCTGCCGATGACCGTCGACGATTTCATGGCTGCCATGTG
CCAGCGCCGCCCGGCCTTTCTCGGCCTGAGCAAACGCTACGCCGGCGCTATCGGTGATGCGCTGGAGCGGGTCGGTATGC
AGGACAAGCGCAAGCGCCGGATGGGTGCGCTGTCCGGTGGCGAACGCCAGCGGGTATTGCTCGCCCAGGGCCTGATTCCG
GCGCCGCAACTGCTGGTGCTGGATGAACCGATGTCGGCCCTCGACGAAGCCGGAATCCAGGTGTTCGAGCGTTTGCTGGG
TGACTGGCGCGCGGCGGGCATCACCGTGCTGTGGATCGAGCACGATCTGGAAGCGGTCGGGCGTCTGGCCAATCGCGTCA
CCGGCCTCAACCGCCGGGTGCTGTTCGACGCCTCGCCGCAACAGGCCCTGACCCCGGAACGTCTGCTGACCCTGTTCTCG
ACCCATCCACGGAGCGCTGCCTGA

Upstream 100 bases:

>100_bases
TGTCGCACATTTCCTACGGCGAATACACCGCCGACAAGTACGAAAAGGAAATGACCGGCAACCTCAACACCGTGGTTCGG
GCGATTCAGGAGTCCGGCGC

Downstream 100 bases:

>100_bases
TGAGTTACGAAGCCTTTCGTTTGATGGTGCAAGGCTGGGCTTCCTCCGGTTACCTGCCGGAAGCCCTGGCCTACGGGTTT
GTGGTCAATGCGCTGCTCGC

Product: ABC transporter-like protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MTAQENLSIASSGPTLDFADISLTLGRTTILDKVTFQVQPGSVHALVGPNGGGKSSLIKTLLGQMPHQGRLSLQWPGEPG
TIGYVPQALEFDRGLPMTVDDFMAAMCQRRPAFLGLSKRYAGAIGDALERVGMQDKRKRRMGALSGGERQRVLLAQGLIP
APQLLVLDEPMSALDEAGIQVFERLLGDWRAAGITVLWIEHDLEAVGRLANRVTGLNRRVLFDASPQQALTPERLLTLFS
THPRSAA

Sequences:

>Translated_247_residues
MTAQENLSIASSGPTLDFADISLTLGRTTILDKVTFQVQPGSVHALVGPNGGGKSSLIKTLLGQMPHQGRLSLQWPGEPG
TIGYVPQALEFDRGLPMTVDDFMAAMCQRRPAFLGLSKRYAGAIGDALERVGMQDKRKRRMGALSGGERQRVLLAQGLIP
APQLLVLDEPMSALDEAGIQVFERLLGDWRAAGITVLWIEHDLEAVGRLANRVTGLNRRVLFDASPQQALTPERLLTLFS
THPRSAA
>Mature_246_residues
TAQENLSIASSGPTLDFADISLTLGRTTILDKVTFQVQPGSVHALVGPNGGGKSSLIKTLLGQMPHQGRLSLQWPGEPGT
IGYVPQALEFDRGLPMTVDDFMAAMCQRRPAFLGLSKRYAGAIGDALERVGMQDKRKRRMGALSGGERQRVLLAQGLIPA
PQLLVLDEPMSALDEAGIQVFERLLGDWRAAGITVLWIEHDLEAVGRLANRVTGLNRRVLFDASPQQALTPERLLTLFST
HPRSAA

Specific function: Involved in a zinc uptake transport system (Probable) [H]

COG id: COG1121

COG function: function code P; ABC-type Mn/Zn transport systems, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1788165, Length=234, Percent_Identity=35.042735042735, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789873, Length=203, Percent_Identity=32.512315270936, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1790739, Length=251, Percent_Identity=29.8804780876494, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788053, Length=200, Percent_Identity=35, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87081791, Length=220, Percent_Identity=30, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789891, Length=201, Percent_Identity=34.3283582089552, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788761, Length=235, Percent_Identity=28.5106382978723, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790544, Length=243, Percent_Identity=27.1604938271605, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87081834, Length=206, Percent_Identity=32.0388349514563, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788472, Length=257, Percent_Identity=23.3463035019455, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787041, Length=197, Percent_Identity=29.4416243654822, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786803, Length=232, Percent_Identity=26.7241379310345, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786563, Length=229, Percent_Identity=31.4410480349345, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787759, Length=237, Percent_Identity=30.8016877637131, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1786345, Length=257, Percent_Identity=29.1828793774319, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1787164, Length=212, Percent_Identity=30.6603773584906, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1787089, Length=213, Percent_Identity=30.0469483568075, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1789864, Length=239, Percent_Identity=26.7782426778243, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1789593, Length=222, Percent_Identity=25.6756756756757, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788002, Length=237, Percent_Identity=29.1139240506329, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788506, Length=209, Percent_Identity=33.4928229665072, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1786319, Length=208, Percent_Identity=26.9230769230769, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1786975, Length=190, Percent_Identity=30, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693107, Length=231, Percent_Identity=30.7359307359307, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787370, Length=227, Percent_Identity=26.431718061674, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790190, Length=195, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788210, Length=213, Percent_Identity=26.7605633802817, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI48994943, Length=234, Percent_Identity=26.9230769230769, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788897, Length=203, Percent_Identity=28.0788177339901, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1787758, Length=206, Percent_Identity=27.6699029126214, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87081709, Length=224, Percent_Identity=24.1071428571429, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI48995001, Length=200, Percent_Identity=27.5, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787792, Length=199, Percent_Identity=26.6331658291457, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI87082267, Length=202, Percent_Identity=28.2178217821782, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789751, Length=186, Percent_Identity=31.1827956989247, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI2367384, Length=204, Percent_Identity=25.4901960784314, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790467, Length=212, Percent_Identity=24.0566037735849, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788450, Length=227, Percent_Identity=25.5506607929515, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1787182, Length=201, Percent_Identity=31.3432835820896, Blast_Score=61, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17569145, Length=227, Percent_Identity=32.5991189427313, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24662800, Length=220, Percent_Identity=28.6363636363636, Blast_Score=71, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 26730; Mature: 26599

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAQENLSIASSGPTLDFADISLTLGRTTILDKVTFQVQPGSVHALVGPNGGGKSSLIKT
CCCCCCCEEECCCCCEEEEEEEEECCCCEEEEEEEEEECCCCEEEEECCCCCCHHHHHHH
LLGQMPHQGRLSLQWPGEPGTIGYVPQALEFDRGLPMTVDDFMAAMCQRRPAFLGLSKRY
HHHCCCCCCCEEEECCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHH
AGAIGDALERVGMQDKRKRRMGALSGGERQRVLLAQGLIPAPQLLVLDEPMSALDEAGIQ
HHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEHEECCCCCCCCEEEECCCHHHHHHHHHH
VFERLLGDWRAAGITVLWIEHDLEAVGRLANRVTGLNRRVLFDASPQQALTPERLLTLFS
HHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCHHCCHHHHHHHHH
THPRSAA
CCCCCCC
>Mature Secondary Structure 
TAQENLSIASSGPTLDFADISLTLGRTTILDKVTFQVQPGSVHALVGPNGGGKSSLIKT
CCCCCCEEECCCCCEEEEEEEEECCCCEEEEEEEEEECCCCEEEEECCCCCCHHHHHHH
LLGQMPHQGRLSLQWPGEPGTIGYVPQALEFDRGLPMTVDDFMAAMCQRRPAFLGLSKRY
HHHCCCCCCCEEEECCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHH
AGAIGDALERVGMQDKRKRRMGALSGGERQRVLLAQGLIPAPQLLVLDEPMSALDEAGIQ
HHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEHEECCCCCCCCEEEECCCHHHHHHHHHH
VFERLLGDWRAAGITVLWIEHDLEAVGRLANRVTGLNRRVLFDASPQQALTPERLLTLFS
HHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCHHCCHHHHHHHHH
THPRSAA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]